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Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients with Normal Creatinine Or Reduced Renal Function - Article


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Creatinine Clearance


Clinical Trial: Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients with Normal Creatinine Or Reduced Renal Function

This study is currently recruiting patients.

Sponsored by: University Hospital Ghent
Information provided by: University Hospital Ghent

Purpose

The purpose of this study is to evaluate the renal perfusion depending on the MAP.
Condition Intervention
Kidney Failure, Acute
 Procedure: controlling the MAP

MedlinePlus related topics:  Kidney Failure

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Uncontrolled, Crossover Assignment, Efficacy Study

Official Title: MAP and Renal Perfusion: Evaluation of Critically Ill Patients with Normal Creatinine Or Reduced Renal Function

Further Study Details: 
Primary Outcomes: creatinine clearance after 4 hours
Secondary Outcomes: resistance index; diuresis; urinary indices of renal function
Expected Total Enrollment:  60

Study start: February 2003
Last follow-up: May 2005

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Over 18 years old
  • Intensive care patient
  • Treated with vasopressor
  • Given informed consent
  • Arterial infusion
  • A bladder catheter

Exclusion Criteria:

  • Anamneses of hypertension
  • Neurological trauma
  • Acute renal insufficiency other than prerenal or acute tubular necrosis etiology
  • Hepatorenal syndrome
  • Treated with diuretics
  • Mechanical ventilation and unstable

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00117416

Eric Hoste, MD, PhD      0032/9/240.41.97    eric.hoste@UGent.be

Belgium
      University Hospital Ghent, Ghent,  9000,  Belgium; Recruiting
Eric Hoste, MD, PhD  0032/9/240.41.97    eric.hoste@UGent.be 
Eric Hoste, MD, PhD,  Principal Investigator

Study chairs or principal investigators

Eric Hoste, MD, PhD,  Principal Investigator,  University Hospital Ghent   

More Information

Study ID Numbers:  2002/382
Record last reviewed:  May 2005
Last Updated:  July 25, 2005
Record first received:  July 6, 2005
ClinicalTrials.gov Identifier:  NCT00117416
Health Authority: Belgium: Directorate general for the protection of Public health: Medicines
ClinicalTrials.gov processed this record on 2005-07-26


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October 11, 2008



Page Updated: June 1, 2005
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