Article: Rabeprazole

Rabeprazole
Systematic (IUPAC) name
2-[(4-(3-methoxypropoxy)- 3-methyl-pyridin-2-yl) methylsulfinyl]- 1H-benzoimidazole
Identifiers
CAS number	117976-89-3
ATC code	A02BC04
PubChem	5029
DrugBank	APRD01212
Chemical data
Formula	C18H21N3O3S
Mol. weight	359.444
Pharmacokinetic data
Bioavailability	52%
Metabolism	Hepatic
Half life	1 - 1.5 hours
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status	?
Routes	Oral

Rabeprazole is a proton pump inhibitor sold (as its sodium salt) under the brand name Aciphex® and Pariet® (distributed by Janssen-Cilag).

It is used in the treatment of gastric ulcers and GERD (or heartburn). It is taken once/day along with a full glass of water (preferable 30 min before breakfast). The duration of treatment is usually 4 weeks but could be longer if the symptoms persist.

Sometimes, one may start feeling better after a few days but it is essential to complete the full course of treatment.

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