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Clarithromycin |
Biaxin; Biaxin XL |
Clarithromycin Systematic (IUPAC) name 6-(4-dimethylamino-3-hydroxy- 6-methyl-tetrahydropyran-2-yl) oxy-14-ethyl-12,13-dihydroxy- 4-(5-hydroxy-4-methoxy-4,6- dimethyl-tetrahydropyran-2-yl) oxy-7-methoxy-3,5,7,9,11, 13-hexamethyl-1- oxacyclotetradecane-2,10-dione Identifiers CAS number 81103-11-9 ATC code J01FA09 PubChem 84029 DrugBank APRD00181 Chemical data Formula C38H69NO13 Mol. weight 747.953 g/mol Pharmacokinetic data Bioavailability 50% Protein binding ...
Wikipedia - [full article]
Clarithromycin Clinical Trials
- An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.
ClinicalTrials.gov Identifier: NCT00002194 - Completed
HIV Infections
- Chlorambucil Compared With No Further Therapy Following Anti- Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach
ClinicalTrials.gov Identifier: NCT00003617 - Active, not recruiting
stage I gastric cancer
- Chemoprevention Therapy in Treating Patients at High Risk of Developing Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00006219 - Active, not recruiting
Multiple Myeloma
- Phase II Study of Thalidomide, Clarithromycin, Lenalidomide, and Dexamethasone for Newly Diagnosed Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00538733 - Recruiting
Multiple Myeloma
- The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients with Ischemic Heart Disease
ClinicalTrials.gov Identifier: NCT00121550 - Completed
Heart Disease; Cardiovascular Disease
- Phase II Study of Biaxin, Revlimid, and Dexamethasone for Untreated Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00151203 - Active, not recruiting
Multiple Myeloma
- Lenalidomide, Dexamethasone, and Clarithromycin in Treating Patients Who Have Undergone Stem Cell Transplant for Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00445692 - Recruiting
Multiple Myeloma and Plasma Cell Neoplasm
- Phase II Study of Amithiozone (Thiacetazone) for Patients with Mycobacterium Avium Complex Pulmonary Disease
ClinicalTrials.gov Identifier: NCT00004689 - Active, not recruiting
Mycobacterium avium-intracellulare Infection
- Thalidomide, Dexamethasone, and Clarithromycin in Treating Patients Who Have Undergone a Previous Autologous or Syngeneic Bone Marrow or Stem Cell Transplant for Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00182663 - Recruiting
Multiple Myeloma and Plasma Cell Neoplasm
- A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients with AIDS
ClinicalTrials.gov Identifier: NCT00001058 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
ClinicalTrials.gov Identifier: NCT00002682 - Active, not recruiting
mucosa-associated lymphoid tissue; stage I diffuse small lymphocytic/marginal zone lymphoma
- Clarithromycin in Active Crohn's Disease
ClinicalTrials.gov Identifier: NCT00269386 - Recruiting
Crohn's Disease
- The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used with or without Clofazimine in the Treatment of MAC in Patients with AIDS
ClinicalTrials.gov Identifier: NCT00002331 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- Kidney Transplants in People with HIV Infection
ClinicalTrials.gov Identifier: NCT00023478 - Active, not recruiting
HIV Infections; End-Stage Renal Disease
- The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children with AIDS
ClinicalTrials.gov Identifier: NCT00000971 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 mg) or Rifabutin (300 mg) or Placebo
ClinicalTrials.gov Identifier: NCT00002101 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination with Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs Patients
ClinicalTrials.gov Identifier: NCT00002140 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. avium Complex (MAC) Infections in Patients With AIDS
ClinicalTrials.gov Identifier: NCT00000644 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001030 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- The Safety and Effectiveness of Clarithromycin in the Prevention of Mycobacterium avium Complex (MAC) Infection in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002336 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma
ClinicalTrials.gov Identifier: NCT00003151 - Active, not recruiting
contiguous stage II diffuse small lymphocytic/marginal zone lymphoma; stage I diffuse small lymphocytic/marginal zone lymphoma
- The Safety and Effectiveness of Rifabutin, Combined with Clarithromycin or Azithromycin, in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001023 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- Tailored Treatment of H. Pylori Infection Based on SNPs of CYP2C19 and 23S rRNA of H. Pylori
ClinicalTrials.gov Identifier: NCT00149084 - Recruiting
H. pylori infection; Gastritis; Gastric ulcer; Duodenal Ulcer
- Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites
ClinicalTrials.gov Identifier: NCT00000826 - Completed
Bacterial Infections; Mycoses; HIV Infections
- Intravenous Clarithromycin in Septic Syndrome
ClinicalTrials.gov Identifier: NCT00297674 - Completed
Sepsis; Ventilator Associated Pneumonia
- Helicobacter - Lymphoma - Radiation Part I: Eradication, Part II: Radiation
ClinicalTrials.gov Identifier: NCT00154440 - Recruiting
Lymphoma, Mucosa-Associated Lymphoid Tissue; B-cell Non-Hodgkin''y Lymphoma of the stomach, primary gastric
- Selection of Antibiotic Resistance by Azithromycin and Clarithromycin in the Oral Flora
ClinicalTrials.gov Identifier: NCT00354952 - Completed
Healthy Volunteers
- Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the Treatment of Community-Acquired Pneumonia
ClinicalTrials.gov Identifier: NCT00336505 - Completed
Pneumonia
- Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the Treatment of Community-Acquired Pneumonia
ClinicalTrials.gov Identifier: NCT00336544 - Completed
Pneumonia
- Clarithromycin v Ciprofloxacin Added to Rifampicin + Ethambutol, for Opportunist Mycobacterial Pulmonary Disease
ClinicalTrials.gov Identifier: NCT00367913 - Completed
Pulmonary Diseases
- Use of Clarithromycin in Mustard-Induced Bronchiolitis
ClinicalTrials.gov Identifier: NCT00381147 - Completed
Bronchiolitis Obliterans; Acute Obliterating Bronchiolitis
- Pediatric Community-Acquired Pneumonia
ClinicalTrials.gov Identifier: NCT00034736 - Completed
Pneumonia
- Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients with Mycobacterium Avium Complex Bacteremia.
ClinicalTrials.gov Identifier: NCT00002192 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001039 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis
ClinicalTrials.gov Identifier: NCT00000794 - Completed
Toxoplasmosis, Cerebral; HIV Infections
- Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium avium Complex Disease (MAC) Plus AIDS
ClinicalTrials.gov Identifier: NCT00001047 - Terminated
Mycobacterium avium-intracellulare Infection; HIV Infections
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