Alendronate |
Fosamax |
Alendronate Systematic (IUPAC) name sodium [4-amino-1-hydroxy-1-(hydroxy-oxido-phosphoryl)- butyl]phosphonic acid trihydrate Identifiers CAS number 121268-17-5 ATC code M05BA04 PubChem 2088 DrugBank APRD00561 Chemical data Formula C4H18NNaO10P2 Mol. weight 325.124 Pharmacokinetic data Bioavailability 0.6% Metabolism excreted unchanged Half life ? Excretion renal Therapeutic considerations Pregnancy cat. ? Legal status POM (UK) Routes ora ...
Wikipedia - [full article]
Alendronate Clinical Trials
- PaTH Study: Parathyroid Hormone and Alendronate for Osteoporosis
ClinicalTrials.gov Identifier: NCT00005005 - Active, not recruiting
Osteoporosis
- Comparison of Study Drug With Alendronate on How it Effects Glucocorticoid-Induced Osteoporosis
ClinicalTrials.gov Identifier: NCT00051558 - Active, not recruiting
Osteoporosis
- The Effect of Alendronate, Calcium, and Vitamin D on Bone Mineral Density in HIV Infected Patients
ClinicalTrials.gov Identifier: NCT00061256 - Active, not recruiting
HIV Infections
- Efficacy of Alendronate Versus Placebo in the Treatment of HIV-Associated Osteoporosis
ClinicalTrials.gov Identifier: NCT00120757 - Active, not recruiting
Osteoporosis; HIV Infections
- Alendronate to Treat Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome
ClinicalTrials.gov Identifier: NCT00001728 - Active, not recruiting
Polyostotic Fibrous Dysplasia
- Parathyroid Hormone (PTH) with Alendronate for Osteoporosis
ClinicalTrials.gov Identifier: NCT00005006 - Active, not recruiting
Osteoporosis
- Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis Patients
ClinicalTrials.gov Identifier: NCT00157690 - Active, not recruiting
Cystic Fibrosis; Osteoporosis; Bone Diseases, Metabolic
- Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis
ClinicalTrials.gov Identifier: NCT00004489 - Recruiting
Osteoporosis; Cystic Fibrosis
- Study of Transitioning From Alendronate to Denosumab
ClinicalTrials.gov Identifier: NCT00377819 - Active, not recruiting
Postmenopausal Osteoporosis
- Alendronate Prevents Microarchitectural Deterioration of Trabecular Bone in Early Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00504166 - Active, not recruiting
Osteopenia; Osteoporosis
- Phase II Randomized Study of Alendronate Sodium for Osteopenia in Patients with Gaucher's Disease
ClinicalTrials.gov Identifier: NCT00004488 - Recruiting
Gaucher's Disease; Osteopenia
- Safety and Efficacy of Alendronate (Fosamax) in Children With Osteoporosis
ClinicalTrials.gov Identifier: NCT00259857 - Active, not recruiting
Osteoporosis
- Safety/Efficacy of Zoledronic Acid and Alendronate on Bone Metabolism in Post Menopausal Women With Osteoporosis
ClinicalTrials.gov Identifier: NCT00404820 - Active, not recruiting
Osteoporosis
- EVA: Evista Alendronate Comparison
ClinicalTrials.gov Identifier: NCT00035971 - Completed
Osteoporosis
- Alendronate Osteoporosis Study
ClinicalTrials.gov Identifier: NCT00277251 - Active, not recruiting
Glucocorticoid-Associated Osteopenia and Osteoporosis
- A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
ClinicalTrials.gov Identifier: NCT00330460 - Active, not recruiting
Osteoporosis; Osteopenia
- A Multicenter, Randomized Placebo Controlled Pilot MicroCT Study to Estimate the Effect of Treatment With Denosumab (AMG 162) and Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density
ClinicalTrials.gov Identifier: NCT00293813 - Active, not recruiting
Osteoporosis
- Can Alendronate Suppress Calcification and Improve Bone Density in Chronic Peritoneal Dialysis Patients?
ClinicalTrials.gov Identifier: NCT00261625 - Not yet recruiting
End-Stage Renal Disease; Peritoneal Dialysis; Osteoporosis
- The Study of the Early Administration of Alendronate on Prevention of Bone Loss After Hip Fracture.
ClinicalTrials.gov Identifier: NCT00346190 - Recruiting
Osteoporosis
- Treatment of Childhood Osteoporosis with Alendronate (Fosamax)
ClinicalTrials.gov Identifier: NCT00001720 - Completed
Osteoporosis
- Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00019695 - Active, not recruiting
Stage IV Prostate Cancer; Bone Metastases; Adenocarcinoma of the Prostate; Recurrent Prostate Cancer
- Alendronate and/or Parathyroid Hormone for Osteoporosis
ClinicalTrials.gov Identifier: NCT00000400 - Active, not recruiting
Osteoporosis
- Effects of Zoledronic Acid Versu Alendronate on Bone Loss After Kidney and Kidney/Pancreas Transplants
ClinicalTrials.gov Identifier: NCT00580047 - Recruiting
Renal Insufficiency
- The Effects of Alendronate After Cure of Primary Hyperparathyroidism
ClinicalTrials.gov Identifier: NCT00359385 - Recruiting
Hyperparathyroidism
- Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients
ClinicalTrials.gov Identifier: NCT00136058 - Active, not recruiting
Osteoporosis; Hip Fracture
- Effects of Parathyroid Hormone in Men with Osteoporosis
ClinicalTrials.gov Identifier: NCT00000427 - Active, not recruiting
Osteoporosis
- Osteoporosis Prevention With Low Dose Alendronate
ClinicalTrials.gov Identifier: NCT00463268 - Not yet recruiting
Osteopenia
- Study of the Effect of Alendronate on Vascular Calcification and Arterial Stiffness in Chronic Kidney Disease
ClinicalTrials.gov Identifier: NCT00395382 - Recruiting
Vascular Calcification; Arteriosclerosis
- Bisphosphonate and Anastrozole Trial - Bone Maintenance Algorithm Assessment
ClinicalTrials.gov Identifier: NCT00122356 - Recruiting
Breast Cancer
- A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.
ClinicalTrials.gov Identifier: NCT00503113 - Recruiting
Post-Menopausal Osteoporosis
- Alendronate in the Prevention of Collapse of Femoral Head in Non-Traumatic Osteonecrosis
ClinicalTrials.gov Identifier: NCT00265252 - Recruiting
Non-Traumatic Osteonecrosis
- Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Heart Transplantation
ClinicalTrials.gov Identifier: NCT00297830 - Recruiting
Heart Transplantation; Bone Resorption
- Texture Analysis for Postmenopausal Osteoporosis
ClinicalTrials.gov Identifier: NCT00145977 - Recruiting
Osteoporosis; Osteopenia
- Phase II Study of Alendronate Sodium in Children With High-Turnover Idiopathic Juvenile Osteoporosis
ClinicalTrials.gov Identifier: NCT00010439 - Completed
Osteoporosis
- Fosamax Bone Loss Study: Alendronate to Prevent Bone Loss
ClinicalTrials.gov Identifier: NCT00221312 - Recruiting
Perimenopausal Bone Loss
- Alendronate for Vascular Calcification in Peritoneal Dialysis Patients?
ClinicalTrials.gov Identifier: NCT00299572 - Not yet recruiting
Peritoneal Dialysis
- Osteogenesis Imperfecta
ClinicalTrials.gov Identifier: NCT00159419 - Recruiting
Osteogenesis Imperfecta; Osteoporosis; Juvenile Pagets
- Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol.
ClinicalTrials.gov Identifier: NCT00138983 - Completed
Rheumatoid Arthritis; Polymyalgia Rheumatica; Giant Cell Arteritis; Polymyositis; Wegener''s granulomatosis
- Bone Effects of Teriparatide Following Alendronate
ClinicalTrials.gov Identifier: NCT00191893 - Completed
Osteoporosis
- Low-Dose Hormone Replacement Therapy and Alendronate for Osteoporosis
ClinicalTrials.gov Identifier: NCT00000430 - Terminated
Osteopenia; Osteoporosis
- Upper GI Handling of Branded vs. Generic Alendronate
ClinicalTrials.gov Identifier: NCT00400530 - Completed
Osteoporosis
- Evaluation Of Missed Osteoporosis Diagnoses, And Preference Between Once Monthly Ibandronate And Once Weekly Alendronate
ClinicalTrials.gov Identifier: NCT00327990 - Completed
Osteoporosis
- The Change of Bone Markers After Low Dose Alendronate in Postmenopausal Women With Bone Loss
ClinicalTrials.gov Identifier: NCT00460057 - Completed
Osteoporosis
- Pharmacokinetics of a Single 14C-Labeled Dose of Risedronate or Alendronate Followed by Once-a-Week Unlabeled Oral Dose
ClinicalTrials.gov Identifier: NCT00577850 - Completed
Osteopenia; Osteoporosis
- A Comparison Study With Alendronate and Raloxifene in Postmenopausal Women With Osteoporosis
ClinicalTrials.gov Identifier: NCT00389740 - Completed
Osteoporosis, Postmenopausal
- A Study to Compare the Efficacy of Alendronate With and Without Calcium or Calcium Alone In the Treatment of Osteoporosis in Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00398606 - Completed
Osteoporosis, Postmenopausal
- Osteoporosis Prevention After Heart Transplant
ClinicalTrials.gov Identifier: NCT00000412 - Completed
Osteoporosis; Cardiac transplantation
- OPTAMISE: Open-Label Study to Determine How Prior Therapy with Alendronate or Risedronate in Postmenopausal Women with Osteoporosis Influences the Clinical Effectiveness of Teriparatide
ClinicalTrials.gov Identifier: NCT00130403 - Completed
Osteoporosis, Postmenopausal
- Effects of Teriparatide in Postmenopausal Women with Osteoporosis Previously Treated with Alendronate or Raloxifene
ClinicalTrials.gov Identifier: NCT00079924 - Completed
Postmenopausal Osteoporosis
- Bone Loss in Premenopausal Women with Depression
ClinicalTrials.gov Identifier: NCT00006180 - Completed
Depression; Healthy; Osteopenia; Osteoporosis
- Prevention of Osteoporosis in Men with Prostate Cancer
ClinicalTrials.gov Identifier: NCT00048841 - Completed
Prostate Cancer; Osteoporosis; Hypogonadism
- A Randomized Phase II Study of High Dose Ketoconazole Plus Alendronate Versus High Dose Ketoconazole in Patients with Androgen Independent Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00001802 - Completed
Neoplasm Metastasis; Prostatic Neoplasm
- Cancer and Osteoporosis Research With Alendronate and Lupron (C.O.R.A.L )
ClinicalTrials.gov Identifier: NCT00236002 - Terminated
Osteoporosis

Not Signed In -


