High Cholesterol |
Cholesterol, High Blood; High Blood Cholesterol; Hypercholesterolemia; Hyperlipidemia |
Hypercholesterolemia (literally: high blood cholesterol) is the presence of high levels of cholesterol in the blood. It is not a disease but a metabolic derangement that can be secondary to many diseases and can contribute to many forms of disease, most notably cardiovascular disease. It is closely related to the terms "hyperlipidemia" (elevated levels of lipids) and "hyperlipoproteinemia" (elevated levels of lipoproteins). Signs and symptoms Elevated cholesterol does not lead to specif ...
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High Cholesterol Clinical Trials
- A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease
ClinicalTrials.gov Identifier: NCT00535405 - Recruiting
Hypercholesterolemia
- A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk
ClinicalTrials.gov Identifier: NCT00479713 - Recruiting
Hypercholesterolemia
- The Effect of Plant Sterol Supplement on Blood Cholesterol
ClinicalTrials.gov Identifier: NCT00485095 - Recruiting
High Blood Cholesterol Level
- A Mechanistic Study of the Effects of LY518674 on High-Density Lipoprotein Cholesterol (HDL-C) Metabolism
ClinicalTrials.gov Identifier: NCT00327002 - Active, not recruiting
Metabolic Syndrome X
- Effect of TAK-475 or Placebo on Blood Cholesterol Levels in Subjects co-Administered High-Dose Statin
ClinicalTrials.gov Identifier: NCT00249899 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia
- Effect of TAK-475 in Diabetes Patients Needing to Reduce Their Low-Density Cholesterol (“Bad” Cholesterol).
ClinicalTrials.gov Identifier: NCT00251680 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia
- Effect of TAK-475, When Given With Simvastatin, in Patients Needing to Reduce Their Low-Density Cholesterol (“Bad” Cholesterol).
ClinicalTrials.gov Identifier: NCT00256178 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia
- Effect of Policosanol as Monotherapy and Adjunctive to Statin Therapy
ClinicalTrials.gov Identifier: NCT00510809 - Recruiting
High Cholesterol
- Efficacy and Safety of Colesevelam in Pediatric Patients with Genetic High Cholesterol.
ClinicalTrials.gov Identifier: NCT00145574 - Active, not recruiting
Hypercholesterolemia
- Cardiovascular Evaluation of Patients with High Cholesterol and Normal Volunteers
ClinicalTrials.gov Identifier: NCT00001204 - Active, not recruiting
Atherosclerosis; Hypercholesterolemia
- Effect of TAK-475 With or Without Ezetimibe Versus Ezetimibe Alone in Patients With Primary Dyslipidemia Needing to Reduce Their Low-Density Cholesterol (“Bad” Cholesterol).
ClinicalTrials.gov Identifier: NCT00268697 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia
- A Study to Evaluate the Effects of an Investigational Drug on the Postprandial (following a meal) Lipoprotein Response in Patients with Primary Hypercholesterolemia (high cholesterol)
ClinicalTrials.gov Identifier: NCT00101439 - Active, not recruiting
Hypercholesterolemia
- High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly
ClinicalTrials.gov Identifier: NCT00127218 - Active, not recruiting
Atherosclerosis; Cardiovascular Disease
- Evaluation of Combination Cholesterol Treatments in Patients With High Cholesterol.
ClinicalTrials.gov Identifier: NCT00249938 - Completed
Hyperlipidemia; Dyslipidemia
- Safety, Effectiveness, and Tolerability of Ezetimibe Combined with Statins for the Treatment of High Cholesterol in HIV Infected Adults
ClinicalTrials.gov Identifier: NCT00099684 - Active, not recruiting
HIV Infections
- Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy
ClinicalTrials.gov Identifier: NCT00260442 - Recruiting
Sarcopenia; Cardiovascular Disease
- Short-Term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome
ClinicalTrials.gov Identifier: NCT00114634 - Recruiting
- Systematic Management of High Cholesterol Utilizing Computer Monitoring
ClinicalTrials.gov Identifier: NCT00133094 - Recruiting
Hypercholesterolemia
- A Patient-Spouse Intervention for Self-Managing High Cholesterol
ClinicalTrials.gov Identifier: NCT00321789 - Not yet recruiting
Hypercholesterolemia
- Effectiveness of a Vitamin Mineral Supplement
ClinicalTrials.gov Identifier: NCT00153764 - Active, not recruiting
Homocysteine; LDL cholesterol
- Study of High Density Lipoprotein Cholesterol (HDL-C)-Raising Mechanism of Rosuvastatin (CRESTOR™) by Quantifying the Key Steps of Reverse Cholesterol Transport (RCT)
ClinicalTrials.gov Identifier: NCT00240266 - Completed
Metabolic Syndrome; Dyslipidemia
- STOP CAP: Pravastatin and Atorvastatin to Prevent Heart Disease in People With High Cholesterol Level, Diabetes or Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00166036 - Recruiting
Diabetes Mellitus; Metabolic Syndrome X; Hypercholesterolemia
- Study of Drugs for High Blood Pressure and High Cholesterol in American Indians with Type 2 Diabetes at High Risk of Kidney or Heart Disease
ClinicalTrials.gov Identifier: NCT00004266 - Completed
Diabetic Nephropathy
- the Effect of the Alga Dunaliella Bardawil as a Sorce of 9-Cis Retinoic Acid on Lipid Profile in Fibrate Treated Patients.
ClinicalTrials.gov Identifier: NCT00156169 - Recruiting
low HDL Cholesterol
- Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency
ClinicalTrials.gov Identifier: NCT00260299 - Recruiting
Mevalonic Aciduria; Mevalonate Kinase Deficiency; Immune System Diseases; Periodic Fever Syndromes, Hereditary; Lipid Metabolism, Inborn Errors
- Study of an Approved Drug with a Statin (a medication that lowers cholesterol levels) as Compared to Statin Therapy Alone in Patients with High Cholesterol
ClinicalTrials.gov Identifier: NCT00092586 - Completed
Hypercholesterolemia
- A Study To Examine The Effect And Safety Of GW501516 In Subjects Who Have Low Level Of High-Density Lipoprotein Cholesterol (Also Known as "Good Cholesterol")
ClinicalTrials.gov Identifier: NCT00158899 - Completed
Dyslipidaemia
- The Effects of Ezetimibe/Simvastatin Tablet 10/20 mg Versus Doubling the Dose of Simvastatin 20 mg [Simvastatin 40 mg] in High Cholesterol and Coronary Heart Disease (Study P04039)
ClinicalTrials.gov Identifier: NCT00423579 - Recruiting
Hypercholesterolemia; Coronary Disease
- Telemedicine Treatment for Veterans with Gulf War Illness
ClinicalTrials.gov Identifier: NCT00129454 - Active, not recruiting
High utilization
- To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 20 Mg.
ClinicalTrials.gov Identifier: NCT00276458 - Recruiting
Hypercholesterolemia
- To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 Mg.
ClinicalTrials.gov Identifier: NCT00276484 - Recruiting
Hypercholesterolemia
- Midlife Cholesterol Study
ClinicalTrials.gov Identifier: NCT00361075 - Active, not recruiting
Menopause; Postmenopause; Premenopause; Cardiovascular Disease
- Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma
ClinicalTrials.gov Identifier: NCT00006024 - Active, not recruiting
high-grade childhood cerebral astrocytoma
- Effect of TAK-475 and Simvastatin Alone or in Combination on Blood Cholesterol Levels.
ClinicalTrials.gov Identifier: NCT00286481 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia
- Offering Influenza and Pneumococcal Vaccine to Patients Being Evaluated in the Emergency Department
ClinicalTrials.gov Identifier: NCT00380679 - Active, not recruiting
High Risk for Serious Influenza; High Risk for Pneumonia
- Effect of TAK-475 or Placebo on Blood Cholesterol Levels in Subjects co-Administered Rosuvastatin
ClinicalTrials.gov Identifier: NCT00249912 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia
- Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-Cholesterol Levels
ClinicalTrials.gov Identifier: NCT00216463 - Active, not recruiting
Hypercholesterolemia
- To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With High Cholesterol.
ClinicalTrials.gov Identifier: NCT00271817 - Recruiting
Hypercholesterolemia
- High Carbohydrate Vs. High Fat Diets in the Treatment of Obesity
ClinicalTrials.gov Identifier: NCT00123240 - Active, not recruiting
Overweight,; Obesity
- Effect of Prevention Consultations on High Cardiovascular Risk Patients
ClinicalTrials.gov Identifier: NCT00348855 - Active, not recruiting
High Risk Hypertensive Patients
- Intervention Study to Control High Blood Pressure for Korean American
ClinicalTrials.gov Identifier: NCT00473681 - Active, not recruiting
High Blood Pressure
- Cholesterol and Pharmacogenetic Study
ClinicalTrials.gov Identifier: NCT00451828 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia; Coronary Heart Disease; Cardiovascular Disease
- Comparison of High-Dose Chemotherapy + Rituximab and CHOP + Rituximab in High-Risk Follicular Lymphoma
ClinicalTrials.gov Identifier: NCT00435955 - Active, not recruiting
Follicular Lymphoma
- High-Protein and High-Carbohydrate Diets' Effect on Urinary Concentrating Ability
ClinicalTrials.gov Identifier: NCT00282321 - Recruiting
Healthy
- High-Dose Methylprednisolone and Rituximab in High Risk B-CLL
ClinicalTrials.gov Identifier: NCT00558181 - Recruiting
Chronic B-Lymphocytic Leukemia
- Real-Life EValuation Of High Dose RosUvastatin in High Risk Patients After TitraTION
ClinicalTrials.gov Identifier: NCT00526721 - Recruiting
Hypercholesterolemia
- A 12 Week Study to Assess the Effectiveness of an Investigational Cholesterol-Lowering Drug in Patients That Have Been Hospitalized for a Possible Heart Problem
ClinicalTrials.gov Identifier: NCT00132717 - Active, not recruiting
Hypercholesterolemia
- The Low HDL On Six Weeks Statin Therapy (LOW) Study
ClinicalTrials.gov Identifier: NCT00238004 - Active, not recruiting
HDL Cholesterol; Coronary Arteriosclerosis; Lipoproteins
- Effects of Atorvastatin on Disease Activity and HDL Cholesterol Function in Patients With Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00356473 - Active, not recruiting
Rheumatoid Arthritis
- High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Combination Chemotherapy in Treating Women With High-Risk Breast Cancer
ClinicalTrials.gov Identifier: NCT00002784 - Active, not recruiting
Breast Cancer
- The Effects of ProAlgaZyme on HDL Cholesterol in Individuals With Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00518960 - Active, not recruiting
Metabolic Syndrome; Hyperlipidemia
- Effect of TAK-475 or Placebo co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia
ClinicalTrials.gov Identifier: NCT00263081 - Active, not recruiting
Hypercholesterolemia, Familial
- Guided Care: Integrating High Tech and High Touch
ClinicalTrials.gov Identifier: NCT00121940 - Active, not recruiting
Chronic Disease
- Effects of Rosiglitazone on Blood Vessels in Patients with High Blood Pressure and High Cholesterol
ClinicalTrials.gov Identifier: NCT00006071 - Completed
Hypercholestrolemia; Hypertension
- Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study
ClinicalTrials.gov Identifier: NCT00053599 - Active, not recruiting
Alzheimer Disease
- Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High Cholesterol
ClinicalTrials.gov Identifier: NCT00185107 - Completed
Hypercholesterolemia
- MRI for Detecting Cancer in Women Who Are at High Risk of Developing Breast Cancer
ClinicalTrials.gov Identifier: NCT00003736 - Active, not recruiting
Breast Cancer
- Amlodipine/Atorvastatin Combination To Reduce The Health Risk Of High Blood Pressure And High Cholesterol Levels
ClinicalTrials.gov Identifier: NCT00143234 - Completed
Hypertension; Hyperlipidemia
- High-Dose Intravenous (IV) Cyclophosphamide Versus Monthly IV Cyclophosphamide
ClinicalTrials.gov Identifier: NCT00005778 - Active, not recruiting
Lupus Erythematosus, Systemic
- Intralumenal Effects on Cholesterol Absorption/Synthesis
ClinicalTrials.gov Identifier: NCT00328211 - Recruiting
Healthy
- Improving Metabolism With HDL Cholesterol
ClinicalTrials.gov Identifier: NCT00395148 - Recruiting
Heart Disease
- UARK 2003-41: A Study of High-Dose Density Therapy in Patients with Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00113932 - Active, not recruiting
Multiple Myeloma
- The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)
ClinicalTrials.gov Identifier: NCT00346970 - Recruiting
Metabolic Syndrome
- CA-125 in Screening Patients at High Risk for Ovarian Cancer
ClinicalTrials.gov Identifier: NCT00080639 - Active, not recruiting
ovarian epithelial cancer
- H.E.L.P. Apheresis Therapy to Compare the Reduction of LDL Cholesterol
ClinicalTrials.gov Identifier: NCT00526058 - Recruiting
Hypercholesterolemia
- The Effect of Dietary Sitosterol on Blood Sugar and Cholesterol
ClinicalTrials.gov Identifier: NCT00531128 - Recruiting
Sitosterolemia
- SEARCH: Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine
ClinicalTrials.gov Identifier: NCT00124072 - Active, not recruiting
Cardiovascular Disease
- Carboplatin, Temozolomide, and Filgrastim in Treating Patients With Newly Diagnosed or Recurrent High-Grade Glioma
ClinicalTrials.gov Identifier: NCT00006263 - Active, not recruiting
adult brain stem glioma; adult glioblastoma multiforme; high-grade childhood cerebral astrocytoma; adult anaplastic astrocytoma; ...
- The Effect of Lapaquistat Acetate on Blood Cholesterol Levels When Given With Statins
ClinicalTrials.gov Identifier: NCT00532311 - Recruiting
Hypercholesterolemia
- Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006)
ClinicalTrials.gov Identifier: NCT00542971 - Recruiting
AML; High-Risk MDS; Acute Myeloid Leukemia; High-Risk Myelodysplastic Disorder
- To Determine If Chromium Nicotinate Supplementation at 400ug/Day for 16 Weeks Will Improve Insulin Resistance in HIV Patients with Metabolic Abnormalities
ClinicalTrials.gov Identifier: NCT00152893 - Recruiting
HIV; blood sugar > 6.1 mmol/l; triglycerides > 2 mmol/l; total cholesterol > 5.5 mmol/l or HDL < 0.9 mmol/l
- Effect of TAK-475 or Placebo on Blood Cholesterol Levels in Subjects That Are Co-Administered Atorvastatin
ClinicalTrials.gov Identifier: NCT00143676 - Active, not recruiting
Hyperlipidemia; Hypercholesterolemia
- Drug Interaction Study of Lopinavir/Ritonavir and Gemfibrozil
ClinicalTrials.gov Identifier: NCT00474201 - Recruiting
HIV Infections; Cholesterol
- High Fat - High Protein Diet in the Treatment of Obesity
ClinicalTrials.gov Identifier: NCT00299273 - Recruiting
Obesity
- The Anti-Diabetic and Cholesterol-Lowering Effects of Cinnamon and Cassia Bark
ClinicalTrials.gov Identifier: NCT00479973 - Recruiting
Type 2 Diabetes; Hypercholesterolemia
- Carotid Plaque Regression With High Dose Atorvastatin Versus Conventional Dose Simvastatin Using High Field MRI
ClinicalTrials.gov Identifier: NCT00388843 - Recruiting
Carotid Atherosclerosis
- Development of a Hospital Service That Uses Critical Pathway (Protocolized) Care Plans to Provide High-Quality, High-Reliability, Evidence-Based Medical Care
ClinicalTrials.gov Identifier: NCT00275587 - Recruiting
Critical Pathways
- High-Dose Quinapril Versus Low-Dose Quinapril Plus Amlodipine in the Treatment of High-Risk Hypertensive Patients
ClinicalTrials.gov Identifier: NCT00313547 - Recruiting
Hypertension
- The Use of Magnesium to Improve Blood Pressure, Cholesterol, and Glucose Control
ClinicalTrials.gov Identifier: NCT00282659 - Recruiting
Coronary Artery Disease; Hypertension; Dyslipidemia; Diabetes
- High-Dose Total-Body Irradiation, Cyclophosphamide, Antithymocyte Globulin, and Autologous Stem Cell Transplant or High-Dose Cyclophosphamide in Treating Patients With Severe Systemic Sclerosis
ClinicalTrials.gov Identifier: NCT00545038 - Recruiting
Precancerous/Nonmalignant Condition
- A Phase II Study Comparing Low- and High-Dose CAMPATH and High-Dose Rebif in Patients With Early, Active Relapsing-Remitting Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00050778 - Active, not recruiting
Multiple Sclerosis, Relapsing-Remitting
- A Six-Week Randomized Trial of Lipitor(Atorvastatin) for the Treatment of PCOS Women With Elevated LDL Cholesterol
ClinicalTrials.gov Identifier: NCT00529542 - Recruiting
Polycystic Ovary Syndrome
- A Study in People with High Cholesterol
ClinicalTrials.gov Identifier: NCT00133380 - Completed
Hypercholesterolemia
- Modeling DNA Diversity in Reverse Cholesterol Transport
ClinicalTrials.gov Identifier: NCT00064493 - Active, not recruiting
Cardiovascular Diseases; Heart Diseases; Atherosclerosis
- Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome
ClinicalTrials.gov Identifier: NCT00272844 - Enrolling by invitation
Smith-Lemli-Opitz Syndrome
- High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00082797 - Active, not recruiting
adult glioblastoma; adult giant cell glioblastoma; adult gliosarcoma
- Vaccine Therapy in Preventing Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants
ClinicalTrials.gov Identifier: NCT00128661 - Active, not recruiting
Cervical Cancer; high-grade squamous intraepithelial lesion
- Prediction of the Response to Chemotherapy by Tomoscintigraphie the MIBI in the Balance Sheet Pre Hodgkin's Disease and Lymphoma Malins High Grade
ClinicalTrials.gov Identifier: NCT00551798 - Recruiting
Hodgkin's Disease; Malignant Lymphomas High Grade; Chemoresistance
- Sirolimus-Based Immunosuppression in Liver Transplantation for High Risk Hepatocellular Carcinoma Patients
ClinicalTrials.gov Identifier: NCT00328770 - Recruiting
Liver Graft Recipients With High Risk Hepato-Cellular Carcinoma
- A Prospective Comparison of Photorefractive Keratectomy (PRK), PRK With Mitomycin-C and Laser Subepithelial Keratomileusis (LASEK) in the Treatment of Moderate and High Myopia
ClinicalTrials.gov Identifier: NCT00415077 - Recruiting
MODERATE AND HIGH MYOPIA
- Study of Inborn Errors of Cholesterol Synthesis and Related Disorders
ClinicalTrials.gov Identifier: NCT00046202 - Recruiting
Lipoidosis
- Treating Congestive Heart Failure Using a Device to Remove Cholesterol
ClinicalTrials.gov Identifier: NCT00510601 - Recruiting
Heart Decompensation
- Impact of HIV and Its Treatment on Reverse Cholesterol Transport
ClinicalTrials.gov Identifier: NCT00168233 - Recruiting
HIV Infections
- An Investigational Drug Study to Lower Non-Cholesterol Sterol Levels Associated with Sitosterolemia
ClinicalTrials.gov Identifier: NCT00092898 - Active, not recruiting
Lipid Metabolism, Inborn Errors; Heart Disease
- High Legume Diet in Preventing Cancer in Patients at High Risk for Recurrent Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00557063 - Recruiting
Colorectal Cancer
- The Effect of High Dose Vitamin C in Burn Patients
ClinicalTrials.gov Identifier: NCT00350077 - Active, not recruiting
Burns
- Fixation Stability and Bony Healing Following Open Wedge High Tibial Osteotomy
ClinicalTrials.gov Identifier: NCT00284596 - Recruiting
Opening Wedge High Tibial Osteotomy
- High Dose Chemotherapy Followed By PBSC Rescue for HD
ClinicalTrials.gov Identifier: NCT00186251 - Active, not recruiting
Hodgkin Disease
- Gemtuzumab Ozogamicin and High-Dose Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00006265 - Active, not recruiting
recurrent adult acute myeloid leukemia
- Helical Computed Tomography Compared With Chest X-Ray in Screening Individuals at High Risk for Lung Cancer
ClinicalTrials.gov Identifier: NCT00028808 - Active, not recruiting
Small Cell Lung Cancer; Non-small cell lung cancer

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