Naproxen |
Aleve; Anaprox; Anaprox DS; EC-Naprosyn; Naprelan; Naprosyn |
Naproxen Systematic (IUPAC) name (+)-(S)-2-(6-methoxynaphthalen-2-yl) propanoic acid Identifiers CAS number 22204-53-1 ATC code G02CC02 M01AE02, M02AA12 PubChem 1302 DrugBank APRD01135 Chemical data Formula C14H14O3 Mol. weight 230.259 g/mol Pharmacokinetic data Bioavailability 95% (oral) Protein binding 99% Metabolism Hepatic (to 6-desmethylnaproxen) Half life 12–15 hours Excretion Renal Therapeutic considerations Pregnancy cat. C (Au), B ...
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Naproxen Clinical Trials
- Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PN 200 or Naproxen in Subjects Who Are at Risk for Developing NSAID-Associated Ulcers.
ClinicalTrials.gov Identifier: NCT00367211 - Active, not recruiting
Osteoarthritis; Rheumatoid Arthritis; Ankylosing Spondylitis
- Efficacy of Combination Product (Sumatriptan Succinate/Naproxen Sodium) in Eletriptan Non-Responders.
ClinicalTrials.gov Identifier: NCT00382993 - Recruiting
Migraine
- Efficacy of Combination Product (Sumatriptan Succinate/Naproxen Sodium) in Eletriptan Non-Responders.
ClinicalTrials.gov Identifier: NCT00383162 - Recruiting
Migraine
- An Open-Label, Randomized, Comparative 3-Way Cross-Over Study to Evaluate the Effect of Food on the 24-Hour Intragastric pH at Day 5 After Twice Daily Oral Administration of PN 200 (Omeprazole/Naproxen) in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00442208 - Active, not recruiting
Healthy
- PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs Ibuprofen Or Naproxen
ClinicalTrials.gov Identifier: NCT00346216 - Recruiting
Osteoarthritis; Arthritis, Rheumatoid
- Derris Scandens Benth Extract VS Naproxen in Knee OA
ClinicalTrials.gov Identifier: NCT00503828 - Recruiting
Knee Osteoarthritis
- Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee
ClinicalTrials.gov Identifier: NCT00435292 - Recruiting
Osteoarthritis
- A Phase II Trial of Calcitriol and Naproxen in Patients With Recurrent Prostate Cancer
ClinicalTrials.gov Identifier: NCT00383487 - Recruiting
Prostate Cancer
- A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)
ClinicalTrials.gov Identifier: NCT00004845 - Completed
Alzheimer Disease
- Oral Vs Rectal Admin of Naproxen for Post-Vag Perineal Pain Control
ClinicalTrials.gov Identifier: NCT00222976 - Completed
post-vaginal delivery perineal pain
- Celecoxib Versus Naproxen for Prevention of Recurrent Ulcer Bleeding in Arthritis Patients
ClinicalTrials.gov Identifier: NCT00153660 - Recruiting
Arthritis; Cardiovascular Diseases; Cerebrovascular Disorders
- Study Evaluating the Gastrointestinal Safety of PLA-695 Compared to Placebo and Naproxen
ClinicalTrials.gov Identifier: NCT00366262 - Completed
Healthy
- An Effectiveness and Safety Study of IDEA-033 in Comparison to Oral Naproxen and Placebo for the Treatment of Osteoarthritis of the Knee
ClinicalTrials.gov Identifier: NCT00211549 - Completed
Osteoarthritis, Knee
- A Long-Term Safety Study of IDEA-033 in Comparison to Oral Naproxen for the Treatment of Osteoarthritis of the Knee
ClinicalTrials.gov Identifier: NCT00265304 - Completed
Osteoarthritis, Knee
- Safety and Efficacy of Lumiracoxib Versus Naproxen in Acute Musculoskeletal Pain
ClinicalTrials.gov Identifier: NCT00170898 - Completed
Musculoskeletal Pain
- Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)
ClinicalTrials.gov Identifier: NCT00007189 - Completed
Alzheimer Disease
- Celebrex Los Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population.
ClinicalTrials.gov Identifier: NCT00137033 - Completed
Peptic Ulcers
- Effects of Naproxen on Physical Performance
ClinicalTrials.gov Identifier: NCT00410995 - Terminated
Healthy
- Dental Pain (Following Third Molar Tooth Extraction) Study
ClinicalTrials.gov Identifier: NCT00114049 - Completed
Pain; Postoperative Pain
- A Safety and Effectiveness Study of Acetaminophen (4000 mg/Day) and Naproxen (750 mg/Day) in the Treatment of Osteoarthritis of the Hip or Knee
ClinicalTrials.gov Identifier: NCT00240773 - Completed
Osteoarthritis, Knee; Osteoarthritis, Hip
- A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee
ClinicalTrials.gov Identifier: NCT00396955 - Terminated
Osteoarthritis
- A Study of Rofecoxib Versus Naproxen in the Treatment of Chinese Patient with Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00157872 - Terminated
Rheumatoid Arthritis

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