Mometasone Nasal Spray

Nasonex

Article: Mometasone furoate

Image:Mometasone furoate.png
Mometasone furoate
Systematic (IUPAC) name
9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15, 16-octahydrocyclopenta[a]phenanthren-3-one
Identifiers
CAS number	105102-22-5 83919-23-7 as Furoate
ATC code	D07AC13 D07XC03, R01AD09, R03BA07
PubChem	123620
DrugBank	APRD00289
Chemical data
Formula	C₂₂H₂₈Cl₂O₄ for Mometasone C₂₇H₃₀O₆Cl₂ as Furoate
Mol. weight	427.361 g/mol
Pharmacokinetic data
Bioavailability	Nasal spray is virtually undetectable in plasma
Protein binding	98% to 99%
Metabolism	hepatic
Half life	5.8 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	topical, nasal

Mometasone furoate (also referred to as Mometasone) is a moderately potent glucocorticoid steroid used in the treatment of inflammatory skin disorders (such as eczema and psoriasis) and allergic rhinitis (such as hayfever) unresponsive to less potent corticosteroids. It is marketed by Schering-Plough under the brand names Elocon® as a cream or ointment and as Nasonex® nasal spray.

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Retrieved from "http://en.wikipedia.org/wiki/Mometasone_furoate"

Categories: Glucocorticoids | Pharmacology stubs

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