Tramadol |
Ultram |
Tramadol Systematic (IUPAC) name rac-(1R,2R)-2-(dimethylaminomethyl)-1- (3-methoxyphenyl)-cyclohexanol Identifiers CAS number 27203-92-5 ATC code N02AX02 PubChem 33741 DrugBank APRD00028 Chemical data Formula C16H25NO2 Mol. weight 263.4 g/mol Pharmacokinetic data Bioavailability 68-72% Increases with repeated dosing. Metabolism Hepatic demethylated & glucuronidated Half life 5-7 hours Excretion Renal Therapeutic considerations Pregnancy cat. ...
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Tramadol Clinical Trials
- Opioid Withdrawal Suppression with Tramadol - 1
ClinicalTrials.gov Identifier: NCT00142896 - Active, not recruiting
Opioid Dependence
- Pain Relief - Tramadol versus Ibuprofen
ClinicalTrials.gov Identifier: NCT00111046 - Active, not recruiting
Choroidal melanoma; Melanoma; Eye Neoplasms
- An Open Label Study to Evaluate Safety, Tolerability and Clinical Utility of ULTRACET® (37.5mg Tramadol Hydrochloride/325mg Acetaminophen) for the Treatment of Breakthrough Pain in Cancer Patients
ClinicalTrials.gov Identifier: NCT00576173 - Active, not recruiting
Pain
- Comparison of Tramadol Vs Remifentanyl Patient Controlled Analgesia for Second Trimester Abortions
ClinicalTrials.gov Identifier: NCT00361686 - Recruiting
Abortion,Induced
- Comparison Between Tramadol Hcl and Other Analgesics in the Treatment of Renal Colic
ClinicalTrials.gov Identifier: NCT00310908 - Recruiting
Renal Calculus
- Assessment of Tramadol as a Treatment for Opioid Addiction
ClinicalTrials.gov Identifier: NCT00301210 - Recruiting
Opioid-Related Disorders
- A Comparison of the Effectiveness and Safety of ULTRACET® (Tramadol Hydrochloride/Acetaminophen) Versus ULTRAM® (Tramadol Hydrochloride) Versus Placebo in Patients With Pain After Oral Surgery
ClinicalTrials.gov Identifier: NCT00236483 - Completed
Pain, Postoperative; Surgery, Oral
- Tramadol iv. : Influence of Dose and Dose Intervals on Therapeutic Accuracy and Side Effects When Used for Postoperative Pain Relief in Ambulatory Surgery
ClinicalTrials.gov Identifier: NCT00333346 - Recruiting
Ambulatory Surgery
- RCT on Ketorolac and Tramadol in Bone Fractures Pain of Child
ClinicalTrials.gov Identifier: NCT00560443 - Not yet recruiting
Fracture; Pain
- Norspan® Patches Versus Tramadol in Subjects With Chronic, Moderate to Severe Osteoarthritis Pain in the Hip and/or Knee
ClinicalTrials.gov Identifier: NCT00426647 - Not yet recruiting
Osteoarthritis; Pain
- Tramadol and Pain Sensitization
ClinicalTrials.gov Identifier: NCT00487175 - Not yet recruiting
Pain
- Comparison of Butorphanol and Tramadol Associated PCA After Hysterectomy
ClinicalTrials.gov Identifier: NCT00510666 - Completed
Postoperative Pain
- The Discriminative Effects of Tramadol in Humans
ClinicalTrials.gov Identifier: NCT00499746 - Not yet recruiting
Opioid Abuse; Opioid Addiction; Stimulant Abuse; Stimulant Addiction
- A Randomised Open Controlled Parallel Group Study Comparing Norspan and Tramadol
ClinicalTrials.gov Identifier: NCT00399178 - Completed
Osteoarthritis
- A Study Comparing the Effectiveness and Safety of Extended Release Tramadol Versus Placebo for the Treatment of Osteoarthritis (OA) of the Knee
ClinicalTrials.gov Identifier: NCT00348010 - Completed
Chronic Pain
- A Study Comparing the Effectiveness and Safety of Tramadol HCl/Acetaminophen Versus Placebo for the Treatment of Painful Neuropathy in Diabetic Patients
ClinicalTrials.gov Identifier: NCT00210847 - Completed
Diabetic Neuropathies
- A Study Comparing the Effectiveness and Safety of Extended-Release Tramadol Versus Placebo in the Treatment of Chronic Low Back Pain
ClinicalTrials.gov Identifier: NCT00347724 - Completed
Chronic Pain
- A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 Mg) of Extended-Release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or Hip
ClinicalTrials.gov Identifier: NCT00325858 - Completed
Chronic Pain
- A One-Year, Open-Label Study to Assess the Safety and Effectiveness of Extended Release Tramadol HCl in the Treatment of Chronic, Non-Malignant Pain.
ClinicalTrials.gov Identifier: NCT00347685 - Completed
Chronic Pain
- ULTRACET® (Tramadol Hydrochloride and Acetaminophen) for the Treatment of Rheumatoid Arthritis Pain.
ClinicalTrials.gov Identifier: NCT00246168 - Completed
Arthritis, Rheumatoid
- Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy
ClinicalTrials.gov Identifier: NCT00564603 - Completed
Postoperative Pain; Post Operative Analgesia; Patient-Controlled Analgesia; Abdominal Surgeries
- Celebrex vs Tramadol in the Treatment of Chronic Lower Back Pain.
ClinicalTrials.gov Identifier: NCT00290901 - Completed
Back Pain
- A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament
ClinicalTrials.gov Identifier: NCT00236535 - Completed
Pain; Sprains and Strains
- A Study Comparing the Effectiveness and Safety of ULTRACET® (Tramadol HCl/Acetaminophen) Versus Placebo for the Treatment of Acute Pain From a Migraine Headache
ClinicalTrials.gov Identifier: NCT00297375 - Completed
Head Pain; Headache; Migraine
- A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 Mg, 200 Mg and 300 Mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)
ClinicalTrials.gov Identifier: NCT00348452 - Completed
Chronic Pain
- A Study of the Effectiveness and Safety of Tramadol HCl/Acetaminophen Compared to Placebo in Treating Acute Low Back Pain
ClinicalTrials.gov Identifier: NCT00210561 - Terminated
Low Back Pain; Back Pain

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