Rofecoxib |
Vioxx; Withdrawn from the market |
Rofecoxib Systematic (IUPAC) name 4-(4-methylsulfonylphenyl)-3-phenyl-5H-furan-2-one Identifiers CAS number 162011-90-7 ATC code M01AH02 PubChem 5090 DrugBank APRD00151 Chemical data Formula C17H14O4S Mol. weight 314.357 g/mol Pharmacokinetic data Bioavailability 93% Protein binding 87% Metabolism hepatic Half life 17 hours Excretion biliary/renal Therapeutic considerations Pregnancy cat. C (Australia) Legal status withdrawn Routes oral Ro ...
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Rofecoxib Clinical Trials
- Rofecoxib After Surgery in Treating Patients With Stage II or Stage III Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00031863 - Active, not recruiting
stage II colon cancer; stage III colon cancer; stage II rectal cancer; stage III rectal cancer
- A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)
ClinicalTrials.gov Identifier: NCT00004845 - Completed
Alzheimer Disease
- A Study to Evaluate Rofecoxib Versus Placebo and Diclofenac in Patients with Acute Painful Rotator Cuff Syndrome
ClinicalTrials.gov Identifier: NCT00140933 - Terminated
Pain
- A Study of Rofecoxib in the Treatment of Post-Operative Pain After Total Knee Joint Replacement.
ClinicalTrials.gov Identifier: NCT00140920 - Terminated
Pain
- A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP)
ClinicalTrials.gov Identifier: NCT00140894 - Terminated
Osteoarthritis; Cancer Pain
- A Study of Rofecoxib Versus Naproxen in the Treatment of Chinese Patient with Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00157872 - Terminated
Rheumatoid Arthritis
- 12-Week No-Rofecoxib Plus Aspirin Endoscopy Study
ClinicalTrials.gov Identifier: NCT00543465 - Completed
Arthritis, Rheumatoid; Osteoarthritis
- A Study to Evaluate the Effect of MK0966 (Rofecoxib) on the Recurrence of Colorectal Adenomas
ClinicalTrials.gov Identifier: NCT00282386 - Completed
Colorectal Adenona
- Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery.
ClinicalTrials.gov Identifier: NCT00390260 - Completed
Pain, Postoperative Arthroscopy.
- Rofecoxib to Prevent Pain after Third Molar (Wisdom Tooth) Extraction
ClinicalTrials.gov Identifier: NCT00026819 - Completed
Pain
- A Four-Week Study Comparing Acetaminophen Extended Release and Rofecoxib in the Treatment of Osteoarthritis of the Knee
ClinicalTrials.gov Identifier: NCT00568295 - Completed
Osteoarthritis of the Knee
- GECO: Study of Rofecoxib and Prolonged Constant Infusion of Gemcitabine in the Polychemotherapy Treatment of Advanced Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00385606 - Completed
Advanced Non-Small Cell Lung Cancer
- Rofecoxib and Bupivacaine to Prevent Pain after Third Molar (Wisdom Tooth) Extraction
ClinicalTrials.gov Identifier: NCT00050362 - Completed
Pain; Tooth Extraction

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