Sertraline |
Zoloft |
Image:Zoloft.jpg Sertraline Systematic (IUPAC) name (1S)-cis-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydro-N-methyl- 1-naphthalenamine Identifiers CAS number 79617-96-2 ATC code N06AB06 PubChem 68617 DrugBank APRD00175 Chemical data Formula C17H17NCl2 Mol. weight 342.7 Pharmacokinetic data Bioavailability 95% Metabolism N-demethylation (liver) Half life ~26 hours Excretion Urine Therapeutic considerations Pregnancy cat. C Legal status ℞ Pr ...
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Sertraline Clinical Trials
- Treatments for Psychogenic Nonepileptic Seizures (NES)
ClinicalTrials.gov Identifier: NCT00159965 - Recruiting
Convulsion, Non-Epileptic; Conversion Disorder; Depression; Stress Disorders, Post-Traumatic; Sertraline
- Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression
ClinicalTrials.gov Identifier: NCT00340379 - Active, not recruiting
Affective Disorders
- Ziprasidone and Sertraline in PTSD
ClinicalTrials.gov Identifier: NCT00248261 - Recruiting
Post-Traumatic Stress Disorder
- Treatments for Depression: Drug vs. Psychotherapy
ClinicalTrials.gov Identifier: NCT00043550 - Active, not recruiting
Depression
- A Study of Sertraline to Prevent PTSD
ClinicalTrials.gov Identifier: NCT00182078 - Recruiting
Posttraumatic Stress Disorder; Depression
- Effectiveness of Sertraline in Treating Pathological Gamblers With a Diagnosis of Alcohol Dependence - 1
ClinicalTrials.gov Identifier: NCT00249431 - Recruiting
Alcoholism; Gambling
- Drug Therapy for Alcohol Dependence in Alaska Natives (naltrexone/sertraline)
ClinicalTrials.gov Identifier: NCT00000451 - Completed
Alcoholism
- A Study of Sertraline and Early Alprazolam XR Administration Versus Sertraline Only in Panic Disorder Patients
ClinicalTrials.gov Identifier: NCT00198094 - Completed
Panic Disorder
- Improving Hispanic Retention in Antidepressant Therapy
ClinicalTrials.gov Identifier: NCT00057642 - Active, not recruiting
Depression; Depressive Disorder
- Sertraline and Naltrexone for Alcohol Dependence
ClinicalTrials.gov Identifier: NCT00000440 - Completed
Alcoholism
- Antidepressant Treatment of Melancholia in Late Life
ClinicalTrials.gov Identifier: NCT00000378 - Active, not recruiting
Depression; Melancholia
- Child and Adolescent Anxiety Disorders (CAMS)
ClinicalTrials.gov Identifier: NCT00052078 - Active, not recruiting
Anxiety Disorders
- Treatment of Vascular Depression
ClinicalTrials.gov Identifier: NCT00045773 - Active, not recruiting
Depressive Disorder; Depression
- Sertraline for Alcohol Dependence and Depression
ClinicalTrials.gov Identifier: NCT00004554 - Completed
Alcoholism; Depression
- Sertraline for Preventing Post-Stroke Depression and Improving Rehabilitation Outcomes
ClinicalTrials.gov Identifier: NCT00177424 - Recruiting
Cerebrovascular Accident; Depression
- Therapies for Treatment-Resistant Panic Disorder Symptoms
ClinicalTrials.gov Identifier: NCT00118417 - Active, not recruiting
Panic Disorder
- Depression and Health Outcomes in Refractory Epilepsy
ClinicalTrials.gov Identifier: NCT00026637 - Active, not recruiting
Depression; Epilepsy
- Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder
ClinicalTrials.gov Identifier: NCT00048854 - Active, not recruiting
Premenstrual Syndrome
- The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients
ClinicalTrials.gov Identifier: NCT00581009 - Recruiting
Major Depressive Disorder; Bipolar Disorder
- The Depression in Alzheimer's Disease Study (DIADS)
ClinicalTrials.gov Identifier: NCT00009191 - Active, not recruiting
Alzheimer Disease; Depression
- Research Evaluating the Value of Augmenting Medication with Psychotherapy (REVAMP)
ClinicalTrials.gov Identifier: NCT00057551 - Active, not recruiting
Depression; Depressive Disorder
- Tiagabine, Sertraline, or Donepezil for the Treatment of Cocaine Dependence - 9
ClinicalTrials.gov Identifier: NCT00015132 - Completed
Cocaine-Related Disorders
- Sertraline and Habit Reversal in the Treatment of Patients with Trichotillomania
ClinicalTrials.gov Identifier: NCT00118014 - Completed
Impulse Control Disorders
- Sertraline for Alcoholism
ClinicalTrials.gov Identifier: NCT00368550 - Recruiting
Alcoholism; Alcohol Drinking; Alcohol Dependence
- Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder
ClinicalTrials.gov Identifier: NCT00536198 - Recruiting
Premenstrual Dysphoric Disorder
- Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.
ClinicalTrials.gov Identifier: NCT00421369 - Not yet recruiting
Major Depressive Disorder
- Sertraline and Cognitive Therapy in Depressed Alcoholics
ClinicalTrials.gov Identifier: NCT00000458 - Completed
Alcoholism; Depression
- Civilian Post-Traumatic Stress Disorder Risperidone Clinical Trial
ClinicalTrials.gov Identifier: NCT00133822 - Active, not recruiting
Post-Traumatic Stress Disorder
- Medication Treatment for Psychotic Depression
ClinicalTrials.gov Identifier: NCT00056472 - Recruiting
Depression; Major Depressive Disorder
- Sertraline vs. Placebo for Symptoms Following Traumatic Brain Injury
ClinicalTrials.gov Identifier: NCT00208585 - Recruiting
Traumatic Brain Injury
- Cognitive Behavioral Therapy Vs. Sertraline in the Treatment of Post-Traumatic Stress Disorder
ClinicalTrials.gov Identifier: NCT00391430 - Recruiting
Post-Traumatic Stress Disorder
- Pharmacologic Treatment of PTSD in Sexually Abused Children
ClinicalTrials.gov Identifier: NCT00078767 - Active, not recruiting
Posttraumatic Stress Disorder; Major Depressive Disorder; Anxiety Disorders
- Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders
ClinicalTrials.gov Identifier: NCT00182533 - Recruiting
Phobia, Social; Panic Disorder; Agoraphobia; Obsessive-Compulsive Disorder; Anxiety Disorders; Major Depressive Disorder
- Treatment of Cholestatic Pruritus With Sertraline
ClinicalTrials.gov Identifier: NCT00058903 - Completed
Pruritus; Liver Cirrhosis, Biliary; Hepatitis C
- Depression in Alzheimer's Disease (DIADS-2)
ClinicalTrials.gov Identifier: NCT00086138 - Recruiting
Alzheimer's Disease; Depression
- Bipolar II Depression: Lithium, SSRI, or the Combination
ClinicalTrials.gov Identifier: NCT00276965 - Recruiting
Bipolar II Depression
- Comparison of Two Treatments for Post-Traumatic Stress Disorder
ClinicalTrials.gov Identifier: NCT00127673 - Recruiting
Post-Traumatic Stress Disorder
- Antidepressant Medication Treatment for Depression in Individuals with Congestive Heart Failure
ClinicalTrials.gov Identifier: NCT00078286 - Recruiting
Heart Failure, Congestive; Depression
- Combined Treatment for Alcohol-Dependent Women With PTSD
ClinicalTrials.gov Identifier: NCT00262223 - Recruiting
Co-Morbid Alcohol and Other Drug Use Disorders (AOD); Post-Tramautic Stress Disorder (PTSD)
- Omega-3 for Depression and Other Cardiac Risk Factors
ClinicalTrials.gov Identifier: NCT00116857 - Recruiting
Cardiovascular Diseases; Depression; Heart Diseases; Myocardial Infarction; Angina, Unstable
- Sertraline Compared With Hypericum Perforatum (St. John's Wort) in Treating Mild to Moderate Depression in Patients With Cancer
ClinicalTrials.gov Identifier: NCT00066859 - Completed
Depression; unspecified adult solid tumor, protocol specific
- Sertraline vs. Venlafaxine XR
ClinicalTrials.gov Identifier: NCT00179283 - Completed
Major Depressive Disorder
- Flushes and Sertraline Trial
ClinicalTrials.gov Identifier: NCT00283192 - Completed
Menopause-Hot Flashes
- Sertraline for the Treatment of Patients with Frontal Lobe Dementia (FLD)
ClinicalTrials.gov Identifier: NCT00001777 - Completed
- The Effectiveness of Sertraline in Patients Who Have Had Inadequate Response to Escitalopram
ClinicalTrials.gov Identifier: NCT00179257 - Completed
Major Depressive Disorder
- Sertraline for the Prevention of Recurrent Postpartum Depression
ClinicalTrials.gov Identifier: NCT00276900 - Completed
Depression
- Sequenced Treatment Alternatives to Relieve Depression (STAR*D)
ClinicalTrials.gov Identifier: NCT00021528 - Completed
Depression
- Treatment of Obsessive-Compulsive Disorder (OCD) in Children
ClinicalTrials.gov Identifier: NCT00000384 - Completed
Obsessive-Compulsive Disorder
- Treatment of Adolescent Suicide Attempters (TASA)
ClinicalTrials.gov Identifier: NCT00080158 - Completed
Major Depressive Disorder; Depressive Disorder not otherwise specified (NOS); Dysthymic Disorder
- Triidothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression.
ClinicalTrials.gov Identifier: NCT00158990 - Completed
Major depression; Bipolar Disorder; Unipolar Depression
- Drug Treatment for Alcoholics with Post-Traumatic Stress Disorder
ClinicalTrials.gov Identifier: NCT00000446 - Completed
Alcoholism; Post-Traumatic Stress Disorder
- Treatment of Major Depression with St. John's Wort (Hypericum)
ClinicalTrials.gov Identifier: NCT00005013 - Completed
Major depression
- Study Of Indiplon/Placebo With Sertraline In Insomnia Co-Existing With Depression
ClinicalTrials.gov Identifier: NCT00232167 - Terminated
Insomnia; Depression
- Phase II Study of Stereotypes and Mental Retardation: Neurobiological Basis
ClinicalTrials.gov Identifier: NCT00004300 - Suspended
stereotyped behavior; Mental Retardation
- A Ten-Week Study Evaluating The Effectiveness And Safety Of Zoloft In Children And Adolescents With A Diagnosis Of PTSD
ClinicalTrials.gov Identifier: NCT00150306 - Terminated
Stress Disorders, Post-Traumatic
- Multicentre Trial to Evaluate the Safety and Efficacy of Investigational Study Drug in Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00143091 - Terminated
Major Depressive Disorder, Recurrent

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