Abacavir tablets |
abacavir sulfate; Ziagen |
Abacavir Systematic (IUPAC) name [(1R)-4-[2-amino- 6-(cyclopropylamino)purin- 9-yl]-1-cyclopent- 2-enyl]methanol Identifiers CAS number ? ATC code J05AF06 PubChem 441300 DrugBank ? Chemical data Formula C14H18N6O Mol. weight 286.333 Pharmacokinetic data Bioavailability Cmax=3.0 ± 0.89 mcg/mL (dose of 300 mg bid, po) Metabolism Liver Half life 1.54 ± 0.63 hours Excretion Urine [1.2% abacavir, 30% 5'-carboxylic acid metabolite, 36% 5'-glucuronide me ...
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Abacavir tablets Clinical Trials
- A Study to Test the Safety, Tolerance, and Metabolism of Abacavir (1592U89, ABC) With Standard Zidovudine (ZDV) Therapy in Newborn Infants Born to HIV-1 Infected Women
ClinicalTrials.gov Identifier: NCT00000864 - Active, not recruiting
HIV Infections
- Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir)
ClinicalTrials.gov Identifier: NCT00004981 - Active, not recruiting
HIV Infections
- Four-Drug Combination Therapy with Zidovudine, Lamivudine, 1592U89 (Abacavir), and 141W94 (Amprenavir) in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00006617 - Active, not recruiting
HIV Infections
- Safety and Effectiveness of TRIZIVIR (Abacavir/Lamivudine/Zidovudine) with Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00011895 - Active, not recruiting
HIV Infections
- Comparison of GW433908/Ritonavir to Nelfinavir When Used with Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs
ClinicalTrials.gov Identifier: NCT00009061 - Active, not recruiting
HIV Infections
- Safety of and Immune Response to Cyclosporine A in Combination with Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in Adults with Acute HIV Infection
ClinicalTrials.gov Identifier: NCT00084149 - Active, not recruiting
HIV Infections
- Efavirenz Or Atazanazir/Ritonavir Given with Emtricitabine/Tenofovir Disoproxil Fumarate Or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
ClinicalTrials.gov Identifier: NCT00118898 - Active, not recruiting
HIV Infections
- Study of the Effectiveness and Tolerability of OROS Hydromorphone HCI SR(Slow-Release) Tablets and Immediate-Release Hydromorphone Tablets in Patients With Chronic Pain
ClinicalTrials.gov Identifier: NCT00410943 - Active, not recruiting
Pain
- D4T or Abacavir Plus Vitamin Enhancement (DAVE)
ClinicalTrials.gov Identifier: NCT00143702 - Recruiting
Elevated Lactic Acid
- HLA-B*5701 And Hypersensitivity To Abacavir
ClinicalTrials.gov Identifier: NCT00373945 - Active, not recruiting
HIV
- PK, PD and Safety of Multiple Doses of V1512 Tablets in PD Patients Compared to Standard Levodopa/Carbidopa Oral Tablets
ClinicalTrials.gov Identifier: NCT00491998 - Recruiting
Parkinson's Disease
- Clinical Utility Of Genetic Screening For HLA-B*5701, On Susceptibility To Abacavir Hypersensitivity
ClinicalTrials.gov Identifier: NCT00340080 - Active, not recruiting
HIV Infections
- Blood Levels of Abacavir in HIV Infected Adolescents
ClinicalTrials.gov Identifier: NCT00087945 - Completed
HIV Infections
- A Randomized, Prospective Study of the Efficacy, Safety and Tolerability of Two Doses of GW433908Ritonavir Given With Abacavir/Lamivudine Fixed Dose Combination
ClinicalTrials.gov Identifier: NCT00335270 - Active, not recruiting
HIV
- Abacavir/Lamivudine Versus Emtricitabine/Tenofovir Both In Combination With Lopinavir/Ritonavir For The Treatment Of HIV
ClinicalTrials.gov Identifier: NCT00244712 - Active, not recruiting
HIV Infections
- Viral Dynamics and Pharmacokinetics of Abacavir and Tenofovir
ClinicalTrials.gov Identifier: NCT00214890 - Recruiting
HIV Infections
- Induction/Simplification With Atazanavir + Ritonavir + Abacavir/Lamivudine Fixed-Dose Combination In HIV-1 Infection
ClinicalTrials.gov Identifier: NCT00440947 - Active, not recruiting
HIV Infection
- SHARE: Simple HAART With Abacavir, Reyataz, and Epivir
ClinicalTrials.gov Identifier: NCT00426296 - Recruiting
HIV Infections; Lipodystrophy
- Treatment with Combinations of Several Antiviral Drugs in Infants and Young Children with HIV Infection
ClinicalTrials.gov Identifier: NCT00000872 - Active, not recruiting
HIV Infections
- Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth
ClinicalTrials.gov Identifier: NCT00102960 - Active, not recruiting
HIV Infections
- A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy
ClinicalTrials.gov Identifier: NCT00102206 - Active, not recruiting
HIV Infections
- Anti-HIV Drugs During Pregnancy
ClinicalTrials.gov Identifier: NCT00042289 - Active, not recruiting
HIV Infections
- Oxycodone-Naloxone Prolonged Release Tablets in Relieving Opioid-Related Constipation
ClinicalTrials.gov Identifier: NCT00412100 - Active, not recruiting
Pain
- Evolution of L74V or K65R Mutations in VIremic Subjects on Tenofovir Disoproxil Fumarate (TDF) or Abacavir (ABC) (EVITA)
ClinicalTrials.gov Identifier: NCT00312169 - Recruiting
HIV Infections
- Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected with HIV
ClinicalTrials.gov Identifier: NCT00000940 - Active, not recruiting
HIV Infections
- A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002217 - Completed
HIV Infections
- Effectiveness of the Early Addition of Abacavir to an Anti-HIV Drug Combination
ClinicalTrials.gov Identifier: NCT00001132 - Completed
HIV Infections
- HIV Study Of GW433908 Versus Kaletra, Both With Abacavir/lamivudine In Therapy-Naive Patients
ClinicalTrials.gov Identifier: NCT00085943 - Active, not recruiting
HIV Infections
- Blood Levels of Abacavir after One Dose in HIV-Infected Children and Adolescents
ClinicalTrials.gov Identifier: NCT00011479 - Completed
HIV Infections
- Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy
ClinicalTrials.gov Identifier: NCT00008554 - Active, not recruiting
HIV Infections
- An Open-Label Evaluation of the Dose Proportionality of OROS® Hydromorphone HCL Tablets 8mg, 16mg, 32mg, 64mg
ClinicalTrials.gov Identifier: NCT00398957 - Active, not recruiting
Analgesia
- Comparison of Anti-HIV Drug Combinations to Prevent Mother-to-Child Transmission of HIV
ClinicalTrials.gov Identifier: NCT00086359 - Active, not recruiting
HIV Infections
- Phase III Study to Assess the Long Term Efficacy, Carry-Over Effect and Safety of 300 IR Sublingual Immunotherapy Tablets
ClinicalTrials.gov Identifier: NCT00418379 - Active, not recruiting
Allergy
- Treatment of Hepatitis B Virus (HBV) Before Beginning Anti-HIV Drugs in Patients with Both HBV and HIV
ClinicalTrials.gov Identifier: NCT00051090 - Active, not recruiting
HIV Infections; Hepatitis B
- Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets
ClinicalTrials.gov Identifier: NCT00166842 - Active, not recruiting
Transplantation; Kidney Transplantation; Immunosuppression
- Long-Term Administration Study of SND 919 Tablets in Parkinson's Disease
ClinicalTrials.gov Identifier: NCT00274131 - Active, not recruiting
Parkinson Disease
- Changes in the Immune Response and Skin Reactivity of Grass Pollen Allergic Patients Treated With ALK Grass Tablets
ClinicalTrials.gov Identifier: NCT00413556 - Active, not recruiting
Allergy
- Changing to Nonprotease Inhibitor Treatment to Improve Side Effects
ClinicalTrials.gov Identifier: NCT00021463 - Completed
HIV Infections; Lipodystrophy
- A Study of Relapse Prevention and the Effectiveness of Long-Acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schiozaffective Disorder
ClinicalTrials.gov Identifier: NCT00216476 - Active, not recruiting
Schizophrenia; Psychotic Disorders
- A Repeated Dose Study of the Metabolism and Action Evaluation of OROS Hydromorphone HCI (Slow Release) Tablets in Patients With Chronic Pain
ClinicalTrials.gov Identifier: NCT00410878 - Active, not recruiting
Analgesics, Opioid.; Pain
- An Open-Label Study to Evaluate the Efficacy and Safety of Amprenavir (141W94) and Abacavir Combination Therapy in Protease Inhibitor Experienced Subjects with HIV-1 Infection Who Are Failing Their Current Antiretroviral Treatment Regimen
ClinicalTrials.gov Identifier: NCT00002205 - Completed
HIV Infections
- Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients
ClinicalTrials.gov Identifier: NCT00028314 - Active, not recruiting
HIV Infections; Lipodystrophy; Wasting Disease
- Adefovir Dipivoxil Tablets (10mg) In Chinese Subjects With HBe Antigen Negative Chronic Hepatitis B
ClinicalTrials.gov Identifier: NCT00324961 - Active, not recruiting
Chronic Hepatitis B
- A Study of the Efficacy and Safety of Long-Acting Injectable Risperidone and Risperidone Tablets in Patients With Schizophrenia
ClinicalTrials.gov Identifier: NCT00240708 - Active, not recruiting
Schizophrenia
- Conversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial Epilepsy
ClinicalTrials.gov Identifier: NCT00355082 - Active, not recruiting
Epilepsy, Partial
- The STEAL Study
ClinicalTrials.gov Identifier: NCT00192634 - Recruiting
HIV
- Lopinavir Capsules to Kaletra or Invirase Tablets
ClinicalTrials.gov Identifier: NCT00438152 - Recruiting
HIV Infections
- When to Start Anti-HIV Drugs in Children Infected With HIV
ClinicalTrials.gov Identifier: NCT00234091 - Recruiting
HIV Infections
- Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment
ClinicalTrials.gov Identifier: NCT00005017 - Active, not recruiting
HIV Infections
- Clinical Trial to Evaluate the Efficacy and the Safety of Antihypertensive Tablets
ClinicalTrials.gov Identifier: NCT00553865 - Recruiting
Essential Hypertension
- A MULTICENTER, OPEN-LABEL, RANDOMIZED CROSSOVER TRIAL TO ASSESS SUBJECT PREFERENCE FOR ALPRAZOLAM ORALLY DISINTEGRATING TABLETS COMPARED TO CONVENTIONAL ALPRAZOLAM TABLETS IN SUBJECTS WITH ANXIETY
ClinicalTrials.gov Identifier: NCT00139854 - Completed
Anxiety
- A Study to Compare Three Doses of T-20 When Given in Combination with Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected Adults
ClinicalTrials.gov Identifier: NCT00002239 - Completed
HIV Infections
- Safety, Tolerability and Pharmacodynamic Effects of Sublingual Immunotherapy (Tablets) With Recombinant Bet v1
ClinicalTrials.gov Identifier: NCT00396149 - Recruiting
Allergy
- A Long-Term Safety Study to Evaluate Methylphenidate HCL Tablets at Multiple Dose Levels in Adults With Attention Deficit Hyperactivity Disorder
ClinicalTrials.gov Identifier: NCT00326300 - Active, not recruiting
Attention Deficit Hyperactivity Disorder
- A Study of the Safety and Effectiveness of Combination Anti-HIV Therapy in HIV-Infected Adults
ClinicalTrials.gov Identifier: NCT00004585 - Completed
HIV Infections
- Safety and Effectiveness of Giving Adefovir Dipivoxil Plus Abacavir Plus Efavirenz Plus Amprenavir to HIV-Infected Patients Who Have Failed to Respond to Previous Protease Inhibitor Treatment
ClinicalTrials.gov Identifier: NCT00002419 - Completed
HIV Infections
- Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Children Suffering From Grass Pollen Rhinoconjunctivitis
ClinicalTrials.gov Identifier: NCT00409409 - Recruiting
Allergy
- Comparing the Effectiveness of a Triple Nucleoside Reverse Transcriptase Inhibitor Regimen Versus a Protease Inhibitor-Based Regimen In the Prevention of Mother-to-Child Transmission of HIV
ClinicalTrials.gov Identifier: NCT00270296 - Recruiting
HIV Infections
- Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.
ClinicalTrials.gov Identifier: NCT00356915 - Active, not recruiting
Onychomycosis of the Toenail
- Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV Infection
ClinicalTrials.gov Identifier: NCT00013520 - Completed
HIV Infections
- Anti-HIV Drugs for Ugandan Patients With HIV and Tuberculosis
ClinicalTrials.gov Identifier: NCT00078247 - Recruiting
HIV Infections; Tuberculosis
- Efficacy and Safety of Fentanyl Buccal Tablets Compared With Oxycodone for the Management of Break Through Pain
ClinicalTrials.gov Identifier: NCT00463047 - Recruiting
Chronic Pain
- Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients
ClinicalTrials.gov Identifier: NCT00541385 - Recruiting
Malaria
- Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy For Subjects With Mild To Moderate Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00348309 - Recruiting
Alzheimer Disease
- An Observational Study of Olanzapine Coated and Orodispersible Tablets Effectiveness in Schizophrenic and Bipolar Outpatients.
ClinicalTrials.gov Identifier: NCT00510211 - Recruiting
Schizophrenia; Bipolar Disorder
- Factors Predicting Efficacy of Allergen Injection Immunotherapy for Grass Pollen Hayfever: a Pilot Study.
ClinicalTrials.gov Identifier: NCT00135629 - Active, not recruiting
Seasonal Allergic Rhinoconjunctivitis
- Study of AKR-501 Tablets Taken Orally Once Daily for 28 Days in Patients With ITP
ClinicalTrials.gov Identifier: NCT00441090 - Recruiting
Chronic Idiopathic Thrombocytopenic Purpura (ITP)
- A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002362 - Suspended
HIV Infections
- Study of Talabostat and Rituximab in Advanced Chronic Lymphocytic Leukemia (CLL)
ClinicalTrials.gov Identifier: NCT00086203 - Active, not recruiting
Chronic Lymphocytic Leukemia
- A Study of Abacavir Plus Indinavir Sulfate Plus Efavirenz in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001086 - Completed
HIV Infections
- The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Hysterectomized Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00141557 - Recruiting
Menopause
- A Phase 3, Randomized, Open-Label, Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice-Daily Administration, When Co-Administered With NRTIs in Antiretroviral Naive HIV-1 Infected Subjects
ClinicalTrials.gov Identifier: NCT00262522 - Active, not recruiting
HIV Infection
- Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy In Subjects With Mild To Moderate Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00348140 - Recruiting
Alzheimer's Disease
- Rosiglitazone (Extended Release Tablets) Monotherapy In Subjects With Mild To Moderate Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00428090 - Recruiting
Alzheimer's Disease
- A Study of Lopinavir/Ritonavir Tablets Comparing Once-Daily Versus Twice-Daily Dosing in Antiretroviral-Experienced, HIV-1 Infected Subjects
ClinicalTrials.gov Identifier: NCT00358917 - Recruiting
HIV Infection
- TMC278-TiDP6-C215: A Clinical Trial in Treatment naïve HIV-1 Patients Comparing TMC278 to Efavirenz in Combination With Abacavir + Lamivudine
ClinicalTrials.gov Identifier: NCT00543725 - Not yet recruiting
HIV-1; HIV Infections
- The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Non-Hysterectomized Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00141544 - Recruiting
Menopause
- Long-Term Safety Study of Sublingual Fentanyl Tablets in Cancer Patients
ClinicalTrials.gov Identifier: NCT00263575 - Recruiting
Pain; Cancer
- Efficacy and Safety of Sublingual Fentanyl Tablets in Treatment of Breakthrough Pain in Cancer Patients.
ClinicalTrials.gov Identifier: NCT00262678 - Recruiting
Pain; Cancer
- Fuzheng Huayu Tablets Against Posthepatitic Cirrhosis
ClinicalTrials.gov Identifier: NCT00543426 - Recruiting
Posthepatitic Cirrhosis
- A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV Infection
ClinicalTrials.gov Identifier: NCT00006154 - Not yet recruiting
HIV Infections
- Post Marketing Surveillance Study to Observe Safety and Efficacy of Champix® Tablets
ClinicalTrials.gov Identifier: NCT00483002 - Not yet recruiting
Smoking Cessation
- Study of Nitazoxanide Tablets in the Treatment of Mild to Moderate Active Crohn''s Disease
ClinicalTrials.gov Identifier: NCT00130390 - Recruiting
Crohn''s Disease
- Effect of Adjuvant Treatment With Compound Cranberry Extract Tablets in Acute Bacterial Cystitis.
ClinicalTrials.gov Identifier: NCT00305071 - Not yet recruiting
Pyuria; Urinary Tract Infections
- Study of TLK199 Tablets in Myelodysplastic Syndrome (MDS)
ClinicalTrials.gov Identifier: NCT00280631 - Recruiting
Myelodysplastic Syndrome (MDS)
- Effects of Cranberry-Containing Products in Women with Recurrent Urinary Tract Infections (UTIs)
ClinicalTrials.gov Identifier: NCT00100061 - Recruiting
Urinary Tract Infection
- A Study To Look At The Starting Dose Of Ropinirole Immediate Release Tablets In Young Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00140712 - Recruiting
Restless Legs Syndrome
- Clinical Evaluation of Ropinirole PR/XR Tablets in Monotherapy for Parkinson's Disease (PD)
ClinicalTrials.gov Identifier: NCT00434304 - Not yet recruiting
Parkinson's Disease
- Antiretroviral Treatment Simplification Study With Efavirenz + Abacavir + 3TC Once Daily
ClinicalTrials.gov Identifier: NCT00314626 - Completed
HIV Infections
- Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches
ClinicalTrials.gov Identifier: NCT00313105 - Not yet recruiting
Tobacco Dependence
- Oral CF101 Tablets and Methotrexate Treatment in Rheumatoid Arthritis Patients
ClinicalTrials.gov Identifier: NCT00556894 - Not yet recruiting
Rheumatoid Arthritis
- A Multicenter, Open-Label Trial to Assess Subject Preference of PARCOPA, Carbidopa/Levodopa Orally Disintegrating Tablets, Compared to Conventional Carbidopa/Levodopa Tablets in Subjects with Stable Parkinson''s Disease
ClinicalTrials.gov Identifier: NCT00139867 - Completed
Parkinson''s Disease
- Compliance With Once-Daily Divalproex Extended-Release Tablets (Depakote-ER) Versus Multiple-Daily Dose Valproic Acid Capsules (Depakene) in Epilepsy:
ClinicalTrials.gov Identifier: NCT00356018 - Not yet recruiting
Epilepsy
- Phase II Comparator Study of Substitution of Tenofovir or Abacavir Receiving Thymidine Analogue as Part of HAART.
ClinicalTrials.gov Identifier: NCT00270556 - Completed
HIV
- Clinical Evaluation of Ropinirole CR-RLS ( SK&F106064)Tablets in Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00530790 - Not yet recruiting
Restless Legs Syndrome
- Mycophenolate Mofetil and Abacavir Treatment in HIV Patients with Failed Anti-HIV Treatment
ClinicalTrials.gov Identifier: NCT00021489 - Terminated
HIV Infections
- Continued Antiretroviral Therapy with Abacavir, Amprenavir and Efavirenz
ClinicalTrials.gov Identifier: NCT00001758 - Completed
HIV Infection
- Comparison of Abacavir Following Once-Daily And Twice-Daily Administration In HIV Infected Subjects
ClinicalTrials.gov Identifier: NCT00320307 - Completed
HIV Infections
- Intravenous azithromycin plus intravenous ceftriaxone followed by oral azithromycin with intravenous levofloxacin followed by oral levofloxacin for the treatment of moderate to severely ill hospitalized patients with community acquired pneumonia.
ClinicalTrials.gov Identifier: NCT00035347 - Completed
Pneumonia
- Drug Interactions Among Anti-HIV Agents
ClinicalTrials.gov Identifier: NCT00001766 - Completed
HIV Infection

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