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Treatment of High Blood Pressure Using Olmesartan with Hydrochlorothiazide Compared to an ACE Inhibitor with a Calcium Channel Blocker - Article


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Quinapril and Hydrochlorothiazide

Accuretic; Quinaretic


Clinical Trial: Treatment of High Blood Pressure Using Olmesartan with Hydrochlorothiazide Compared to an ACE Inhibitor with a Calcium Channel Blocker

This study is not yet open for patient recruitment.
Verified by Sankyo Pharma Development September 2005

Sponsored by: Sankyo Pharma Inc.
Information provided by: Sankyo Pharma Development
ClinicalTrials.gov Identifier: NCT00185120

Purpose

A comparison of 2 different combinations of high blood pressure medications to treat hypertension
Condition Intervention Phase
Hypertension
 Drug: Olmesartan medoxomil
 Drug: Hydroclorothiazide
 Drug: Benazepril
 Drug: Amlodipine
Phase IV

MedlinePlus related topics:  High Blood Pressure

Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Active Control, Parallel Assignment, Safety/Efficacy Study

Official Title: A Study on the Efficacy and Safety of Olmesartan Medoxomil and Its Combination with Hydrochlorothiazide Compared with an ACE Inhibitor and Its Combination with a Calcium Channel Blocker in Patients with Stage 2 Hypertension

Further Study Details: 
Primary Outcomes: Change in systolic blood pressure from the start of the study
Secondary Outcomes: Change in diastolic blood pressure from the start of the study; Percent of patients who achieve target blood pressure goals
Expected Total Enrollment:  152

Study start: September 2005

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Greater than 18 years of age
  • Patients with high blood pressure

Exclusion Criteria:

  • Hypertensive encephalopathy, stroke or transient ischemic attack within the past 6 months
  • History of myocardial infarction, percutaneous transluminal coronary revascularization, coronary artery bypass graft, and/or unstable angina pectoris within the past 6 months
  • Type 1 diabetes mellitus

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00185120


Alabama
      Mobile,  Alabama,  36693,  United States
Afifa Kirolos  2516605244 

California
      Memorial Research Medical Center, Long Beach,  California,  90806,  United States
Betty Gauss  562-595-9366 

      National Research Institute, Los Angeles,  California,  90057,  United States
Jose Garcia  213-413-2500 

      Orange County Research Center, Tustin,  California,  92780,  United States
Veronica Raz  714-532-5327 

      Westlake Medical Center, Westlake Village,  California,  91361,  United States
Jamie Plocky  805-496-3322 

      Apex Research Institute, Santa Ana,  California,  92705,  United States
Tawni Niekirk  714-542-3008 

      Clinical Trials Research, Roseville,  California,  95661,  United States
Becky Allgaier  916-781-6718 

Florida
      SFBC International, Miami,  Florida,  33142,  United States
Marco Ordonez  305-634-0777 

      The Greater Fort Lauderdale Heart Group Research, Fort Lauderdale,  Florida,  33308,  United States
Kay Soderholm  954-561-9151 

      CLIRECO, Inc., Tamarac,  Florida,  33321,  United States
Maria Schwartz  954-724-3232 

      Clinical Research of South Florida, Coral Gables,  Florida,  33134,  United States
Pam Reichert  305-445-5637 

Indiana
      Midwest Institute for Clinical Research, Indianapolis,  Indiana,  46260,  United States
Kristin Chionh  317-705-7050 

Kansas
      Heartland Research Associates, Wichita,  Kansas,  67207,  United States
Brad Bagby  316-689-6635 

Louisiana
      New Orleans Center for Clinical Research, New Orleans,  Louisiana,  70119,  United States
Annette Barnes  504-821-8158 

Maine
      Androscoggin Cardiology Research, Auburn,  Maine,  04210,  United States
Michelle Bergeron, RN  207-782-4022 

North Carolina
      Internal Medicine Associates of Charlotte, Charlotte,  North Carolina,  28211,  United States
Donna Acampora  704-366-0080 

      Piedmont Medical Research Associates, Winston Salem,  North Carolina,  27103,  United States
Joanna Zackamerek  336-768-8062 

Ohio
      The Lindner Clinical Trial Center, Cincinnati,  Ohio,  45319,  United States
Jane Schwartz  513-585-1777 

Rhode Island
      Omega Medical Research, Warwick,  Rhode Island,  02886,  United States
Joy Greer, RN  401-739-9350 

Texas
      Punzi Medical Center, Carrollton,  Texas,  75006,  United States
Connie Punzi  972-478-7700 
Ann Meeks  9724787700 

More Information

Study ID Numbers:  866-447
Last Updated:  September 15, 2005
Record first received:  September 9, 2005
ClinicalTrials.gov Identifier:  NCT00185120
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-09-20


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September 6, 2008



Page Updated: June 1, 2005
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