This study will last up to 62 weeks. Subjects will visit the clinic up to 17 times. Certain clinic visits will include a physical examination, medical history review and lung function tests. All study related medications and medical examinations will be provided at no cost to the subject. The drugs used in this study are approved for the age group under study.

Condition	Treatment or Intervention	Phase
Asthma	Drug: fluticasone propionate/salmeterol powder  Drug: fluticasone propionate powder	Phase IV

Ages Eligible for Study:  12 Years   -   65 Years,  Genders Eligible for Study:  Both

Criteria

Inclusion criteria:

• Eligible participants are 12-65 years of age.
• African descent
• Have had asthma for at least 6 months
• Taking a low dose of an inhaled corticosteroid for at least one month before the study (such as fluticasone propionate or budesonide).

Exclusion criteria:

• Have ever had asthma that was life-threatening or were in the hospital for asthma in the 3 months before the study.
• Have a respiratory tract infection, or will not be able to attend all clinic visits for the 62 weeks of the study.
• Have certain conditions that would make study participation unsafe (such as congestive heart failure, uncontrolled hypertension, tuberculosis or certain drug allergies).

The study doctor will evaluate other inclusion and exclusion criteria.

Alabama
      Birmingham,  Alabama,  35205,  United States; Recruiting
      Birmingham,  Alabama,  35209,  United States; Recruiting
      Birmingham,  Alabama,  35294,  United States; Not yet recruiting
      Mobile,  Alabama,  36608,  United States; Recruiting
Arkansas
      Little Rock,  Arkansas,  72205,  United States; Not yet recruiting
California
      Los Angeles,  California,  90048,  United States; Recruiting
      Long Beach,  California,  90806,  United States; Not yet recruiting
      Walnut Creek,  California,  94598,  United States; Recruiting
      Oakland,  California,  94609,  United States; Not yet recruiting
Connecticut
      Hartford,  Connecticut,  06105,  United States; Not yet recruiting
District of Columbia
      Washington,  District of Columbia,  20060,  United States; Not yet recruiting
Florida
      Jacksonville,  Florida,  32205,  United States; Not yet recruiting
      Tallahassee,  Florida,  32308,  United States; Recruiting
Georgia
      Decatur,  Georgia,  30033,  United States; Not yet recruiting
      Atlanta,  Georgia,  30342,  United States; Not yet recruiting
      Martinez,  Georgia,  30907,  United States; Not yet recruiting
      Savannah,  Georgia,  31406,  United States; Recruiting
      Albany,  Georgia,  31707,  United States; Recruiting
      Columbus,  Georgia,  31904,  United States; Recruiting
Illinois
      Maywood,  Illinois,  60153,  United States; Not yet recruiting
      Flossmoor,  Illinois,  60422,  United States; Not yet recruiting
      Chicago,  Illinois,  60637,  United States; Not yet recruiting
Kentucky
      Owensboro,  Kentucky,  42301,  United States; Not yet recruiting
Louisiana
      Lafayette,  Louisiana,  70503,  United States; Recruiting
      Sunset,  Louisiana,  70584,  United States; Recruiting
Maryland
      Bethesda,  Maryland,  20814,  United States; Recruiting
      Wheaton,  Maryland,  20902,  United States; Recruiting
      Baltimore,  Maryland,  21236,  United States; Recruiting
Massachusetts
      Boston,  Massachusetts,  02114,  United States; Not yet recruiting
Michigan
      Detroit,  Michigan,  48201,  United States; Not yet recruiting
Minnesota
      Minneapolis,  Minnesota,  55455,  United States; Not yet recruiting
Mississippi
      Jackson,  Mississippi,  39202,  United States; Not yet recruiting
      Picayune,  Mississippi,  39466,  United States; Not yet recruiting
Missouri
      St. Louis,  Missouri,  63110,  United States; Not yet recruiting
      St. Louis,  Missouri,  63141,  United States; Recruiting
New Jersey
      Verona,  New Jersey,  07044,  United States; Recruiting
New York
      New York,  New York,  10032,  United States; Not yet recruiting
      Brooklyn,  New York,  11215,  United States; Not yet recruiting
      West Sayville,  New York,  11796,  United States; Not yet recruiting
North Carolina
      Winston Salem,  North Carolina,  27157,  United States; Not yet recruiting
      High Point,  North Carolina,  27262,  United States; Recruiting
      Chapel Hill,  North Carolina,  27599,  United States; Not yet recruiting
      Durham,  North Carolina,  27710,  United States; Not yet recruiting
      Elizabeth City,  North Carolina,  27909,  United States; Recruiting
      Charlotte,  North Carolina,  28207,  United States; Not yet recruiting
Ohio
      Sylvania,  Ohio,  43560,  United States; Recruiting
      Cleveland,  Ohio,  44106,  United States; Not yet recruiting
      Cincinnati,  Ohio,  45231,  United States; Recruiting
Oklahoma
      Oklahoma City,  Oklahoma,  73120,  United States; Recruiting
Pennsylvania
      Philadelphia,  Pennsylvania,  19102,  United States; Not yet recruiting
      Philadelphia,  Pennsylvania,  19104,  United States; Not yet recruiting
      Philadelphia,  Pennsylvania,  19107,  United States; Recruiting
South Carolina
      Orangeburg,  South Carolina,  29118,  United States; Not yet recruiting
      Charleston,  South Carolina,  29406,  United States; Recruiting
      Charleston,  South Carolina,  29407,  United States; Recruiting
      Greenville,  South Carolina,  29607,  United States; Recruiting
Tennessee
      Nashville,  Tennessee,  37203,  United States; Not yet recruiting
      Nashville,  Tennessee,  37208,  United States; Not yet recruiting
      Chattanooga,  Tennessee,  37421,  United States; Not yet recruiting
      Knoxville,  Tennessee,  37920,  United States; Not yet recruiting
      Knoxville,  Tennessee,  37922,  United States; Not yet recruiting
Texas
      Dallas,  Texas,  75230,  United States; Not yet recruiting
Virginia
      Richmond,  Virginia,  23225,  United States; Recruiting
      Richmond,  Virginia,  23229,  United States; Not yet recruiting
Wisconsin
      Madison,  Wisconsin,  53792,  United States; Not yet recruiting

Study ID Numbers:  SFA103153
Record last reviewed:  February 2005
Last Updated:  February 1, 2005
Record first received:  February 1, 2005
ClinicalTrials.gov Identifier:  NCT00102765
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-04-08