Dactinomycin |
Actinomycin D; Cosmegen |
Image:Actinomycin.png Actinomycin Systematic (IUPAC) name (Dactinomycin ) Identifiers CAS number 50-76-0 ATC code L01DA01 PubChem 2019 DrugBank APRD00124 Chemical data Formula C62H86N12O16 Mol. weight 1255.42 g/mol Pharmacokinetic data Bioavailability ? Protein binding 5% Metabolism ? Half life 36 hours Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Actinomycin is any of a class of polyp ...
Wikipedia - [full article]
Dactinomycin Clinical Trials
- Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia
ClinicalTrials.gov Identifier: NCT00003702 - Active, not recruiting
Hydatidiform Mole; uterine choriocarcinoma; nonmetastatic gestational trophoblastic tumor; good prognosis metastatic gestational trophoblastic tumor
- Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma
ClinicalTrials.gov Identifier: NCT00245089 - Recruiting
Sarcoma
- Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal Rhabdomyosarcoma
ClinicalTrials.gov Identifier: NCT00245141 - Recruiting
Sarcoma
- Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma
ClinicalTrials.gov Identifier: NCT00075582 - Recruiting
adult soft tissue sarcoma; embryonal childhood rhabdomyosarcoma; embryonal-botryoid childhood rhabdomyosarcoma; ...
- Chemotherapy Plus Surgery in Treating Children at Risk of or With Stage I Wilms' Tumor
ClinicalTrials.gov Identifier: NCT00003804 - Active, not recruiting
stage I Wilms' tumor
- Vincristine and Dactinomycin With or Without Doxorubicin and Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor
ClinicalTrials.gov Identifier: NCT00352534 - Recruiting
Kidney Cancer
- Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma
ClinicalTrials.gov Identifier: NCT00002516 - Active, not recruiting
metastatic tumors of the Ewing's family; localized tumors of the Ewing's family
- Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma
ClinicalTrials.gov Identifier: NCT00072280 - Active, not recruiting
childhood fibrosarcoma; nonmetastatic childhood soft tissue sarcoma
- Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma
ClinicalTrials.gov Identifier: NCT00002898 - Active, not recruiting
Ewing's family of tumors; childhood rhabdomyosarcoma; childhood soft tissue sarcoma
- Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma
ClinicalTrials.gov Identifier: NCT00002766 - Active, not recruiting
Philadelphia chromosome positive chronic myelogenous leukemia; adult acute lymphoblastic leukemia; adult lymphoblastic lymphoma; ...
- Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors
ClinicalTrials.gov Identifier: NCT00025441 - Active, not recruiting
childhood rhabdomyosarcoma; childhood soft tissue sarcoma; female reproductive cancer; Gastrointestinal Cancer; musculoskeletal cancer; Osteosarcoma
- Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma
ClinicalTrials.gov Identifier: NCT00003955 - Active, not recruiting
adult soft tissue sarcoma; alveolar childhood rhabdomyosarcoma; childhood malignant mesenchymoma; embryonal childhood rhabdomyosarcoma; ...
- Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor
ClinicalTrials.gov Identifier: NCT00047138 - Recruiting
Wilms' Tumor; Wilms' tumor and other childhood kidney tumors
- Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery
ClinicalTrials.gov Identifier: NCT00004250 - Active, not recruiting
stage III adult soft tissue sarcoma; recurrent adult soft tissue sarcoma; stage III melanoma; Stage IV Melanoma; Recurrent Melanoma; ...
- Intrathecal and Systemic Chemotherapy Combined With Radiation Therapy in Treating Young Patients With Newly Diagnosed Central Nervous System Atypical Teratoid/Rhabdoid Tumors
ClinicalTrials.gov Identifier: NCT00084838 - Recruiting
childhood rhabdoid tumor of the central nervous system
- Dactinomycin in Treating Patients With Persistent or Recurrent Gestational Trophoblastic Neoplasia
ClinicalTrials.gov Identifier: NCT00003688 - Completed
recurrent gestational trophoblastic tumor; nonmetastatic gestational trophoblastic tumor; good prognosis metastatic gestational trophoblastic tumor
- Combination Chemotherapy and Peripheral Stem Cell Transplantation With or Without Radiation Therapy and/or Surgery in Treating Patients With Ewing's Sarcoma
ClinicalTrials.gov Identifier: NCT00020566 - Recruiting
localized tumors of the Ewing's family; metastatic tumors of the Ewing's family
- Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplantation in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney
ClinicalTrials.gov Identifier: NCT00025103 - Recruiting
recurrent Wilms' tumor and other childhood kidney tumors; clear cell sarcoma of the kidney
- Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma
ClinicalTrials.gov Identifier: NCT00003958 - Completed
childhood rhabdomyosarcoma; childhood soft tissue sarcoma; Muscle Cancer
- Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors
ClinicalTrials.gov Identifier: NCT00002610 - Completed
recurrent Wilms' tumor and other childhood kidney tumors; clear cell sarcoma of the kidney; rhabdoid tumor of the kidney
- Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors
ClinicalTrials.gov Identifier: NCT00002489 - Completed
stage IV ovarian germ cell tumor; extragonadal germ cell tumor; stage II ovarian germ cell tumor; stage III ovarian germ cell tumor; ...
- Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
ClinicalTrials.gov Identifier: NCT00002995 - Completed
adult soft tissue sarcoma; childhood malignant mesenchymoma; embryonal childhood rhabdomyosarcoma; embryonal-botryoid childhood rhabdomyosarcoma; ...
- Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer
ClinicalTrials.gov Identifier: NCT00002611 - Completed
stage I Wilms' tumor; stage II Wilms' tumor; stage III Wilms' tumor; stage IV Wilms' tumor; stage V Wilms' tumor; clear cell sarcoma of the kidney

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