Factor IX Clinical Trials

• Phase I/II Study of Monoclonal Factor IX Concentrate for Factor IX Deficiency
  ClinicalTrials.gov Identifier: NCT00004801 - Completed
  Hemophilia B; Factor IX Deficiency
  
• Post Marketing Study in Haemophilia B Patients Using Nonafact® (Human Coagulation Factor IX)
  ClinicalTrials.gov Identifier: NCT00139828 - Completed
  Hemophilia B
  
• Gene Transfer for Subjects With Hemophilia B Factor IX Deficiency
  ClinicalTrials.gov Identifier: NCT00515710 - Recruiting
  Hemophilia B
  
• Recombinant Human Factor IX (rFIX; BeneFIX®) in Previously Treated Patients (PTPs) with Hemophilia B
  ClinicalTrials.gov Identifier: NCT00093171 - Active, not recruiting
  Hemophilia B
  
• Factor IX Inhibition in Thrombosis Prevention (the FIXIT Trial)
  ClinicalTrials.gov Identifier: NCT00119457 - Active, not recruiting
  Venous Thromboembolism; Embolism and Thrombosis; Hip Fractures
  
• Cooperative Study of Factor VIII Inhibitors
  ClinicalTrials.gov Identifier: NCT00000582 - Completed
  Blood Coagulation Disorders; Hematologic Diseases; Hemophilia A; Hemorrhagic Disorders
  
• Study to Describe the Allergic Reactions to Factor IX in Patients With Hemophilia B
  ClinicalTrials.gov Identifier: NCT00195221 - Completed
  Hemophilia B; Allergic Reactions
  
• Evaluation of Recombinant Human Factor IX (BeneFIX) and a New Formulation of BeneFIX (rFIX-R) in Previously Treated Patients with Moderate to Severe Hemophilia B
  ClinicalTrials.gov Identifier: NCT00093210 - Completed
  Hemophilia B
  
• Recombinant Human Insulin-Like Growth Factor (rhIGF-1)Treatment of Short Stature Associated with IGF-1 Deficiency
  ClinicalTrials.gov Identifier: NCT00125190 - Active, not recruiting
  Insulin-Like Growth Factor-1 Deficiency; Primary IGF-1 Deficiency; IGF-1
  
• Efficacy and Safety Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Previously Untreated Hemophilia A Patients
  ClinicalTrials.gov Identifier: NCT00157157 - Active, not recruiting
  Hemophilia A
  
• Dose Ranging Study of Recombinant Human Insulin-like Growth Factor I in Children with Hyperinsulinism
  ClinicalTrials.gov Identifier: NCT00004699 - Active, not recruiting
  Hyperinsulinism
  
• Phase II Long Term, Randomized Study of Recombinant Human Insulin-like Growth Factor I in Children with Hyperinsulinism
  ClinicalTrials.gov Identifier: NCT00004700 - Active, not recruiting
  Hyperinsulinism
  
• NGR-TNF in Treating Patients With Advanced Solid Tumors
  ClinicalTrials.gov Identifier: NCT00098943 - Active, not recruiting
  adult solid tumor; Endocrine Cancer; Gastrointestinal Cancer; Head and Neck Cancer; kidney and urinary cancer
  
• Prepubertal Children with Growth Failure Associated with Primary IGF-1 Deficiency
  ClinicalTrials.gov Identifier: NCT00125164 - Active, not recruiting
  Insulin-Like Growth Factor-1 Deficiency; Primary IGF-1 Deficiency
  
• The Serum Tissue Factor Level in Lung Cancer Patients as a Prognostic Factor
  ClinicalTrials.gov Identifier: NCT00257179 - Recruiting
  Lung Cancer
  
• Biological Therapy in Treating Patients With Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00005853 - Active, not recruiting
  Myelodysplastic Syndromes
  
• Biological Therapies Following Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Advanced Breast Cancer
  ClinicalTrials.gov Identifier: NCT00005993 - Active, not recruiting
  Lymphoma; Breast Cancer
  
• Recombinant Human Keratinocyte Growth Factor in Unrelated and Related Transplants
  ClinicalTrials.gov Identifier: NCT00056875 - Active, not recruiting
  Graft Versus Host Disease
  
• Effects of Epidermal Growth Factor Receptor Inhibitors on the Skin of Cancer Patients Receiving Epidermal Growth Factor Receptor Inhibitors
  ClinicalTrials.gov Identifier: NCT00483457 - Recruiting
  Unspecified Adult Solid Tumor, Protocol Specific
  
• Factor V Leiden Mutation and Implantation Failure
  ClinicalTrials.gov Identifier: NCT00194350 - Active, not recruiting
  Infertility
  
• Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00023959 - Active, not recruiting
  Head and Neck Cancer
  
• Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis
  ClinicalTrials.gov Identifier: NCT00089167 - Active, not recruiting
  primary systemic amyloidosis
  
• PEG-Interferon alfa-2b, Sargramostim, and Thalidomide in Treating Patients With Metastatic Kidney Cancer
  ClinicalTrials.gov Identifier: NCT00090870 - Active, not recruiting
  Stage IV Renal Cell Cancer
  
• Prophylaxis Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A
  ClinicalTrials.gov Identifier: NCT00243386 - Recruiting
  Hemophilia A
  
• Combination Chemotherapy With or Without Thalidomide in Treating Patients With Multiple Myeloma
  ClinicalTrials.gov Identifier: NCT00028886 - Active, not recruiting
  stage II multiple myeloma; stage III multiple myeloma
  
• Radiation Therapy in Treating Patients With Prostate Cancer
  ClinicalTrials.gov Identifier: NCT00003290 - Active, not recruiting
  stage II prostate cancer; stage III prostate cancer
  
• SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
  ClinicalTrials.gov Identifier: NCT00026377 - Active, not recruiting
  stage II prostate cancer; stage III prostate cancer; stage IV prostate cancer; adenocarcinoma of the prostate
  
• Vaccine Therapy and GM-CSF in Treating Patients With Prostate Cancer That Progressed After Surgery and/or Radiation Therapy
  ClinicalTrials.gov Identifier: NCT00108732 - Active, not recruiting
  recurrent prostate cancer; stage I prostate cancer; stage II prostate cancer; stage III prostate cancer
  
• Combination Chemotherapy and Filgrastim Followed by Radiation Therapy in Treating Patients With Stage II or Stage IIIA Breast Cancer
  ClinicalTrials.gov Identifier: NCT00007904 - Active, not recruiting
  stage II breast cancer; stage IIIA breast cancer; Male Breast Cancer
  
• Bevacizumab and Combination Chemotherapy in Treating Patients Who Have Undergone Surgery for Breast Cancer That Has Spread to the Lymph Nodes
  ClinicalTrials.gov Identifier: NCT00119262 - Active, not recruiting
  stage II breast cancer; stage IIIA breast cancer; stage IIIB breast cancer; Male Breast Cancer
  
• Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1
  ClinicalTrials.gov Identifier: NCT00577577 - Recruiting
  Myotonic Dystrophy Type 1
  
• A Pilot Study of Nuclear Factor-Kappa B (NFkB) Inhibition During Induction Chemotherapy for Patients with Acute Non-Lymphocytic Leukemia (ANLL)
  ClinicalTrials.gov Identifier: NCT00156299 - Recruiting
  Acute Non-lymphocytic Leukemia
  
• Special Turku Atherosclerosis Risk Factor Intervention Project for Children (STRIP)
  ClinicalTrials.gov Identifier: NCT00223600 - Active, not recruiting
  Atherosclerosis
  
• Thalidomide, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
  ClinicalTrials.gov Identifier: NCT00040937 - Active, not recruiting
  stage I multiple myeloma; stage II multiple myeloma; stage III multiple myeloma
  
• Combination Therapy of Low Doses of rFVIIa and FEIBA for Severe Hemophilia A Patients With an Inhibitor to Factor VIII
  ClinicalTrials.gov Identifier: NCT00284193 - Active, not recruiting
  Hemophilia A
  
• Dose-Response Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A
  ClinicalTrials.gov Identifier: NCT00289536 - Active, not recruiting
  Hemophilia A
  
• Study of Recombinant Human Insulin-Like Growth Factor I in Patients with Severe Insulin Resistance
  ClinicalTrials.gov Identifier: NCT00004419 - Recruiting
  Insulin Resistance; Hyperglycemia
  
• Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma
  ClinicalTrials.gov Identifier: NCT00006113 - Active, not recruiting
  stage III melanoma; Stage IV Melanoma; Recurrent Melanoma
  
• Open-Label Trial of Imatinib Mesylate in Patients With Unresectable Recurrent Glioblastoma Multiforme Expressing PDGFR (Platelet Derived Growth Factor Receptors)
  ClinicalTrials.gov Identifier: NCT00171938 - Active, not recruiting
  Glioblastoma
  
• Combination Chemotherapy, Peripheral Stem Cell Transplantation, Biological Therapy, Pamidronate and Thalidomide in Treating Patients With Multiple Myeloma
  ClinicalTrials.gov Identifier: NCT00004088 - Active, not recruiting
  stage I multiple myeloma; stage II multiple myeloma; stage III multiple myeloma
  
• Colony-Stimulating Factor-1 (CSF-1) and Other Cytokines in Human Endometrial Carcinogenesis
  ClinicalTrials.gov Identifier: NCT00250770 - Active, not recruiting
  Uterine Neoplasms; Endometrial Neoplasms
  
• Family Health Study (Validation of a Family History of Cancer Questionnaire for Risk Factor Surveillance)
  ClinicalTrials.gov Identifier: NCT00341757 - Active, not recruiting
  Cancer
  
• DNA Changes as a Risk Factor for Barrett's Esophagus in Patients With Barrett's Esophagus, Gastroesophageal Reflux, or Gastrointestinal Bleeding
  ClinicalTrials.gov Identifier: NCT00445653 - Active, not recruiting
  Precancerous/Nonmalignant Condition
  
• Safety and Tolerability of Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Neovascular Age-Related Macular Degeneration (AMD)
  ClinicalTrials.gov Identifier: NCT00320775 - Active, not recruiting
  Macular Degeneration
  
• Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD)
  ClinicalTrials.gov Identifier: NCT00320788 - Active, not recruiting
  Macular Degeneration
  
• A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers
  ClinicalTrials.gov Identifier: NCT00351767 - Active, not recruiting
  Diabetic Foot Ulcers
  
• Tandem Autologous Stem Cell Transplantation With or Without Maintenance Therapy After the Second Transplantation Compared With Autologous Stem Cell Transplantation Followed By Matched Sibling Allogeneic Stem Cell Transplantation in Patients With Stage II
  ClinicalTrials.gov Identifier: NCT00075829 - Active, not recruiting
  stage II multiple myeloma; stage III multiple myeloma; refractory plasma cell neoplasm
  
• Safety of a New Type of Treatment Called Gene Transfer for the Treatment of Severe Hemophilia B
  ClinicalTrials.gov Identifier: NCT00076557 - Terminated
  Hemophilia B
  
• A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring Insulin-Like Growth Factor-1 (IGF-1) Levels in Blood
  ClinicalTrials.gov Identifier: NCT00212758 - Active, not recruiting
  Kidney Failure, Chronic; Growth
  
• Preoperative Thalidomide With Radiation Therapy for Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy, Doxorubicin, Ifosfamide, and Dacarbazine for Patients with High or Intermediate Grade Primary Soft Tissue Sarcom
  ClinicalTrials.gov Identifier: NCT00089544 - Active, not recruiting
  stage I adult soft tissue sarcoma; stage II adult soft tissue sarcoma; stage III adult soft tissue sarcoma; recurrent adult soft tissue sarcoma
  
• Effect of OPC Factor on Energy Levels
  ClinicalTrials.gov Identifier: NCT00318019 - Recruiting
  Healthy
  
• Genetic Susceptibility to Factor VIII Inhibitors
  ClinicalTrials.gov Identifier: NCT00344435 - Recruiting
  Hemophilia
  
• Severe Pregnancy Complications Are Associated With Elevated Factor VIII Plasma Activity
  ClinicalTrials.gov Identifier: NCT00573118 - Active, not recruiting
  Pregnancy Complications; Preeclampsia; Placental Abruption; Intrauterine Fetal Growth Restriction; Intrauterine Fetal Death
  
• Trial of Rituximab Versus Oral Cyclophosphamide to Eradicate or Suppress Autoimmune Anti-Factor VIII Antibodies in Patients With Acquired Hemophilia A
  ClinicalTrials.gov Identifier: NCT00306670 - Not yet recruiting
  Acquired Hemophilia A Pts Who Have Developed Anti-Factor VIII Antibodies.
  
• Interactive Multirisk-Factor Intervention for HTN Blacks
  ClinicalTrials.gov Identifier: NCT00207194 - Recruiting
  Hypertension
  
• Aorta Calcium Scoring
  ClinicalTrials.gov Identifier: NCT00496717 - Recruiting
  Patients With at Least One Cardiovascular Risk Factor
  
• Enteric Coating as a Factor in Aspirin Resistance
  ClinicalTrials.gov Identifier: NCT00531362 - Recruiting
  Cardiovascular Disease
  
• Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers
  ClinicalTrials.gov Identifier: NCT00189540 - Active, not recruiting
  Arterial Occlusive Disease; Peripheral Vascular Disease; Ischemia; Ulcers
  
• Biological Therapy in Treating Patients Undergoing Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation for Hematologic Cancer
  ClinicalTrials.gov Identifier: NCT00004061 - Active, not recruiting
  Leukemia; Lymphoma
  
• Changes of Transforming Growth Factor b1 and Procollagen III in Patients With Acute Respiratory Distress Syndrome
  ClinicalTrials.gov Identifier: NCT00440882 - Active, not recruiting
  Acute Respiratory Distress Syndrome
  
• Evaluation of Recombinant Factor VIIa in Patients With Severe Bleeding
  ClinicalTrials.gov Identifier: NCT00184548 - Recruiting
  Trauma
  
• Diet, Genetics, and CVD Risk Factor Response in Blacks
  ClinicalTrials.gov Identifier: NCT00079703 - Active, not recruiting
  Cardiovascular Diseases; Heart Diseases
  
• Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population
  ClinicalTrials.gov Identifier: NCT00533754 - Active, not recruiting
  Age-Related Macular Degeneration
  
• Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors
  ClinicalTrials.gov Identifier: NCT00014456 - Active, not recruiting
  Cancer
  
• Oral Combination Chemotherapy in Treating Elderly Patients With Intermediate or High-Grade Non-Hodgkin's Lymphomas
  ClinicalTrials.gov Identifier: NCT00003113 - Active, not recruiting
  Lymphoma
  
• Thalidomide and Docetaxel in Treating Patients With Advanced Cancer
  ClinicalTrials.gov Identifier: NCT00049296 - Active, not recruiting
  Cancer
  
• SU5416 in Treating Children With Recurrent or Progressive Brain Tumors
  ClinicalTrials.gov Identifier: NCT00006247 - Active, not recruiting
  Brain Cancer
  
• Study of Physical Activity as a Risk Factor for Cancer in Chinese Participants
  ClinicalTrials.gov Identifier: NCT00340067 - Recruiting
  Health Status Unknown
  
• A Study to Evaluate the Efficacy and Safety of Palifermin (Recombinant Human Keratinocyte Growth Factor, rHuKGF) for the Reduction of Oral Mucositis in Subjects with Advanced Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00131638 - Active, not recruiting
  Head and Neck Cancer
  
• Thalidomide in Treating Patients With Myelofibrosis
  ClinicalTrials.gov Identifier: NCT00015821 - Active, not recruiting
  Agnogenic Myeloid Metaplasia
  
• A Phase II Study of Implants of Encapsulated Human NTC-201 Cells Releasing Ciliary Neurotrophic Factor (CNTF) in Participants With Visual Acuity Impairment Associated With Atrophic Macular Degeneration
  ClinicalTrials.gov Identifier: NCT00277134 - Active, not recruiting
  Visual Acuity Impairment; Atrophic Macular Degeneration
  
• Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00082823 - Active, not recruiting
  Cancer
  
• Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00083213 - Active, not recruiting
  Cancer
  
• Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption
  ClinicalTrials.gov Identifier: NCT00427804 - Recruiting
  Rheumatoid Arthritis; Crohn's Disease
  
• Efficacy Study of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVF
  ClinicalTrials.gov Identifier: NCT00565747 - Recruiting
  Infertility
  
• Enzastaurin in Treating Patients With Recurrent Gliomas
  ClinicalTrials.gov Identifier: NCT00112788 - Active, not recruiting
  adult brain tumor
  
• Sorafenib in Treating Patients With Extensive Stage Small Cell Lung Cancer
  ClinicalTrials.gov Identifier: NCT00182689 - Active, not recruiting
  Lung Cancer
  
• Cytarabine and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia
  ClinicalTrials.gov Identifier: NCT00023777 - Active, not recruiting
  Myeloid Leukemia
  
• Combination Chemotherapy and Surgery With or Without G-CSF in Treating Patients With Osteosarcoma
  ClinicalTrials.gov Identifier: NCT00002539 - Active, not recruiting
  localized osteosarcoma
  
• AE-941 in Treating Patients With Relapsed or Refractory Multiple Myeloma
  ClinicalTrials.gov Identifier: NCT00022282 - Active, not recruiting
  refractory plasma cell neoplasm
  
• Thalidomide in Treating Patients With Asymptomatic, Indolent Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
  ClinicalTrials.gov Identifier: NCT00052416 - Active, not recruiting
  adult non-Hodgkin's lymphoma
  
• Phase I, Open-Label, Multi-Center, SIngle-Dose, Dose-Escalating, Safety, Tolerability and Pharmacokinetic Study of GC1008 in Patients with IPF
  ClinicalTrials.gov Identifier: NCT00125385 - Active, not recruiting
  Idiopathic Pulmonary Fibrosis; IPF
  
• Multicomponent Risk Factor Intervention for People With a Severe Mental Illness: a Feasibility Study
  ClinicalTrials.gov Identifier: NCT00350311 - Recruiting
  Psychotic Disorder; Obesity; Behavior, Addictive
  
• FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma
  ClinicalTrials.gov Identifier: NCT00104884 - Active, not recruiting
  intraocular melanoma; Melanoma
  
• Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases
  ClinicalTrials.gov Identifier: NCT00033254 - Active, not recruiting
  brain metastases
  
• Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) with Advate (FLrFVIII) in Hemophilia A
  ClinicalTrials.gov Identifier: NCT00141843 - Active, not recruiting
  Hemophilia A
  
• Sorafenib in Treating Patients with Stage IV Melanoma
  ClinicalTrials.gov Identifier: NCT00119249 - Active, not recruiting
  Stage IV Melanoma
  
• Combination Chemotherapy Plus Rituximab in Treating Patients With Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00005959 - Active, not recruiting
  Lymphoma
  
• Covalent Tolerance Induction to Factor VIII-Prediction of Inhibitors in Hemophilia
  ClinicalTrials.gov Identifier: NCT00178607 - Recruiting
  Hemophilia A
  
• Histoblood Group Antigens as a Risk Factor of Asthma
  ClinicalTrials.gov Identifier: NCT00201266 - Recruiting
  Asthma; Lung Diseases
  
• Lenalidomide and Recombinant Human Stem Cell Factor for Treatment of Myelodysplasia
  ClinicalTrials.gov Identifier: NCT00434239 - Recruiting
  Myelodysplasia
  
• Sorafenib in Treating Patients With Advanced Soft Tissue Sarcomas
  ClinicalTrials.gov Identifier: NCT00217620 - Active, not recruiting
  adult soft tissue sarcoma
  
• Combination Chemotherapy Followed By Radiation Therapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00053768 - Active, not recruiting
  adult non-Hodgkin's lymphoma
  
• Thalidomide in Treating Patients With Recurrent or Persistent Cancer of the Uterus
  ClinicalTrials.gov Identifier: NCT00025220 - Active, not recruiting
  recurrent uterine sarcoma; uterine leiomyosarcoma
  
• TIFACT Study – Tissue Factor Expression by Adipose Tissue in Extremely Obese Subjects.
  ClinicalTrials.gov Identifier: NCT00379704 - Recruiting
  Obesity
  
• Role of Placenta Growth Factor in Sickle Acute Chest Syndrome
  ClinicalTrials.gov Identifier: NCT00448370 - Recruiting
  Anemia, Sickle Cell
  
• Tipifarnib in Treating Patients With Metastatic Malignant Melanoma
  ClinicalTrials.gov Identifier: NCT00060125 - Active, not recruiting
  Stage IV Melanoma; Recurrent Melanoma
  
• Carboplatin Plus Paclitaxel With or Without Continued Low-Dose Paclitaxel in Treating Patients With Early-Stage Ovarian Cancer
  ClinicalTrials.gov Identifier: NCT00003644 - Active, not recruiting
  ovarian epithelial cancer
  
• Thalidomide in Treating Patients With Refractory or Resistant Epithelial Ovarian Cancer
  ClinicalTrials.gov Identifier: NCT00016224 - Active, not recruiting
  recurrent ovarian epithelial cancer
  
• Combination Chemotherapy Plus Filgrastim in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00032149 - Active, not recruiting
  AIDS-Related Lymphoma