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Amoxapine

Asendin

Article: Amoxapine

2042-amoxapine-amoxapine.png
Amoxapine
Systematic (IUPAC) name
 ?
Identifiers
CAS number 14028-44-5
ATC code N06AA17
PubChem 2170
DrugBank APRD00142
Chemical data
Formula C17H16ClN3O
Mol. weight 313.781
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status

?
Routes  ?

Amoxapine (brand-names Asendin®, Asendis®, Defanyl®, Demolox®, Moxadil®) is a tricyclic antidepressant of the dibenzoxazepine class. It is used in the treatment of depression, panic disorders and bipolar disorder.

Amoxapine is a strong reuptake inhibitor of norepinephrine and weak reuptake reuptake inhibitor of serotonin. One of its major metabolites, 7-hydroxyamoxapine, has a dopamine receptor blocking effect.


Monoamine oxidase inhibitors (MAOI): {Harmaline} {Nialamide} {Selegiline} {Isocarboxazid} {Iproniazid} {Iproclozide} {Phenelzine} {Toloxatone} {Tranylcypromine}

Reversible Inhibitor of Monoamine oxidase A (RIMA): {Brofaromine} {Moclobemide}

Dopamine Reuptake Inhibitor (DARI): {Amineptine} {Methylphenidate} {Phenmetrazine} {Vanoxerine} {Nomifensine}

Norepinephrine-dopamine reuptake inhibitors: {Bupropion}

Norepinephrine Reuptake Inhibitor (NRI) or (NARI): {Atomoxetine} {Reboxetine} {Viloxazine} {Maprotiline}

Serotonin-Norepinephrine Reuptake Inhibitor (SNRI): {Desipramine} {Duloxetine} {Milnacipran} {Venlafaxine}

Selective Serotonin Reuptake Inhibitor (SSRI): {Alaproclate} {Etoperidone} {Citalopram} {Escitalopram} {Fluoxetine} {Fluvoxamine} {Paroxetine} {Sertraline} {Zimelidine}

Selective Serotonin Reuptake Enhancer (SSRE): {Tianeptine}

Tricyclic antidepressants (TCA): {Amitriptyline} {Butriptyline} {Clomipramine} {Desipramine} {Dibenzepin} {Dothiepin} {Doxepin} {Imipramine} {Lofepramine} {Nortriptyline} {Protriptyline} {Trimipramine} {Melitracen} {Iprindole} {Opipramol} {Amoxapine}

Tetracyclic antidepressants: {Maprotiline} {Mianserin} {Trazodone} {Nefazodone}

Noradrenergic and Specific Serotonergic Antidepressant (NaSSA): {Mirtazapine}
2043-40px-oblongpills-amoxapine.jpg  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
Retrieved from "http://en.wikipedia.org/wiki/Amoxapine"


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August 21, 2008


Page Updated: July 22, 2006
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