Aspirin, Butalbital, and Caffeine |
Axotal; B-A-C; Butalbital Compound; Fiorgen PF; Fiorinal; Fiortal; Fortabs; Isollyl Improved; Lanorinal; Marnal |
See also: Fioricet, a more preparation using Acetaminophen instead of acetylsalicylic acid. Fiorinal is a combination analgesic medication consisting of acetylsalicylic acid, the barbiturate butalbital and caffeine. Some formulations also contain the opioid codeine. It is used to treat tension headaches and migraines. The mechanism of action is not well understood. Since butalbital is habit-forming, using fiorinal daily can lead to dependency. Fiorinal #3 contains: 30 mg codeine, 50 mg butal ...
Wikipedia - [full article]
Aspirin, Butalbital, and Caffeine Clinical Trials
- Assessment and Treatment of Caffeine Dependence
ClinicalTrials.gov Identifier: NCT00338195 - Recruiting
Self-Identified Problematic Caffeine Use; DSM-IV Substance Dependence as Applied to Caffeine
- A Randomised, Crossover Study Comparing the Biochemical and Platelet Effects of Modified-Release Dipyridamole/Aspirin (200mg/25 Mg Bd; Asasantin Retard®) with Aspirin (75 Mg Qd) in Coronary Artery Disease Patients with Aspirin Resistance Manifesting
ClinicalTrials.gov Identifier: NCT00129038 - Active, not recruiting
Coronary Arteriosclerosis
- Therapeutic Utility of Xolair in Patients Undergoing Aspirin Desensitization
ClinicalTrials.gov Identifier: NCT00555971 - Recruiting
Aspirin Sensitive Rhinosinusitis/Asthma
- Rivaroxaban in Combination With Aspirin Alone or With Aspirin and a Thienopyridine in Subjects With Acute Coronary Syndromes (The ATLAS ACS TIMI 46 Trial)
ClinicalTrials.gov Identifier: NCT00402597 - Recruiting
Myocardial Ischemia
- Aspirin Dose and Atherosclerosis in Patients With Heart Disease
ClinicalTrials.gov Identifier: NCT00272337 - Active, not recruiting
Cardiovascular Diseases; Atherosclerosis; Myocardial Infarction
- Japanese Primary prevention of atherosclerosis with Aspirin for Diabetes (JPAD) Trial
ClinicalTrials.gov Identifier: NCT00110448 - Active, not recruiting
Coronary Disease; Arteriosclerosis; Diabetes Mellitus, Type 2
- TREXIMA Versus Butalbital-Containing Combination Medications for the Acute Treatment of Migraine in Adults
ClinicalTrials.gov Identifier: NCT00573170 - Not yet recruiting
Migraine
- Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00272311 - Active, not recruiting
Cardiovascular Diseases; Metabolic Syndrome X; Atherosclerosis
- Trial of Aspirin and Vitamin E in Women (Women's Health Study - WHS)
ClinicalTrials.gov Identifier: NCT00000479 - Active, not recruiting
Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Heart Diseases; Myocardial Infarction; Myocardial Ischemia; Vascular Diseases
- Aspirin and/or Folic Acid in Preventing Recurrent Colorectal Polyps
ClinicalTrials.gov Identifier: NCT00033319 - Active, not recruiting
prevention of colorectal cancer; Colon Cancer; Rectal Cancer
- Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans?
ClinicalTrials.gov Identifier: NCT00205166 - Recruiting
Coronary Artery Disease
- Dextro-Amphetamine Versus Caffeine in Treatment-Resistant OCD
ClinicalTrials.gov Identifier: NCT00363298 - Recruiting
Obsessive-Compulsive Disorder
- Comparison of Sulindac, Aspirin, and Ursodiol in Preventing Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00062023 - Active, not recruiting
Colorectal Cancer; stage I colon cancer; stage II colon cancer; stage III colon cancer; stage IV colon cancer
- A Parallel Group Study to Compare the Gastroprotective Effects of PA 325 Versus 81 mg Enteric Coated Aspirin
ClinicalTrials.gov Identifier: NCT00441519 - Active, not recruiting
Healthy
- The Effect of Beta-Blockers and Aspirin on Hemostasis and Endothelial Function After Acute Mental Stress
ClinicalTrials.gov Identifier: NCT00174902 - Active, not recruiting
Arteriosclerosis; Stress, Psychological
- Caffeine for Apnea of Prematurity (CAP)
ClinicalTrials.gov Identifier: NCT00182312 - Active, not recruiting
Apnea of Prematurity
- Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Trial
ClinicalTrials.gov Identifier: NCT00041938 - Recruiting
Heart Disease; Stroke; Ischemic Heart Disease; Myocardial Infarction; Atrial Fibrillation
- Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients
ClinicalTrials.gov Identifier: NCT00495092 - Recruiting
Cocaine Related Disorders
- The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease
ClinicalTrials.gov Identifier: NCT00564824 - Recruiting
Coronary Disease
- PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes
ClinicalTrials.gov Identifier: NCT00153062 - Active, not recruiting
Cerebrovascular Accident
- The Effects of Aspirin in Gestation and Reproduction
ClinicalTrials.gov Identifier: NCT00467363 - Recruiting
Birth; Spontaneous Abortion
- Enteric Coating as a Factor in Aspirin Resistance
ClinicalTrials.gov Identifier: NCT00531362 - Recruiting
Cardiovascular Disease
- Aspirin in Treating Patients With Colorectal Cancer That Has Been Surgically Removed
ClinicalTrials.gov Identifier: NCT00002527 - Active, not recruiting
stage I rectal cancer; stage I colon cancer; prevention of colorectal cancer; stage III colon cancer; stage III rectal cancer; stage II colon cancer; ...
- Rabeprazole Protection of Aspirin Induced Gastric Damage.
ClinicalTrials.gov Identifier: NCT00220857 - Recruiting
Normal Subjects
- Aspirin Resistance Following Coronary Bypass Surgery
ClinicalTrials.gov Identifier: NCT00260377 - Recruiting
Ischemic Heart Disease
- Overcome Biochemical Aspirin Resistane Through Cilostazol Combination
ClinicalTrials.gov Identifier: NCT00446641 - Recruiting
Cerebral Infarction
- Effect of Aspirin on Mammogram Density in Healthy Postmenopausal Women With a Moderate or High Level of Breast Density
ClinicalTrials.gov Identifier: NCT00470561 - Active, not recruiting
Breast Cancer; Healthy, no Evidence of Disease
- Japanese Primary Prevention Project With Aspirin
ClinicalTrials.gov Identifier: NCT00225849 - Recruiting
Hypertension; Hyperlipidemia; Diabetes Mellitus
- JASAP: Japanese Aggrenox Stroke Prevention vs. Aspirin Programme
ClinicalTrials.gov Identifier: NCT00311402 - Recruiting
Cerebrovascular Accident
- Clopidogrel and Aspirin Together: The Effect on C-Reactive Protein Trial
ClinicalTrials.gov Identifier: NCT00343876 - Recruiting
Coronary Artery Disease
- Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection
ClinicalTrials.gov Identifier: NCT00265408 - Active, not recruiting
Ischemic Stroke; Cervicocephalic Arterial Dissection
- Coronary Care Caffeine
ClinicalTrials.gov Identifier: NCT00137098 - Completed
Myocardial Infarction
- The Effect of Caffeine on Ischemic Preconditioning
ClinicalTrials.gov Identifier: NCT00184912 - Completed
Caffeine; Ischemic Preconditioning; Ischemia-Reperfusion Injury
- Cilostazol-Aspirin Therapy Against Recurrent Stroke With Intracranial Artery Stenosis
ClinicalTrials.gov Identifier: NCT00333164 - Recruiting
Cerebrovascular Disorders
- Study of Tirofiban Administration in Patients With Aspirin Resistance.
ClinicalTrials.gov Identifier: NCT00398463 - Recruiting
Angioplasty, Transluminal, Percutaneous Coronary
- Aspirin Non-Responsiveness and Clopidogrel Endpoint Trial.
ClinicalTrials.gov Identifier: NCT00222261 - Recruiting
Coronary Heart Disease; Angina Pectoris; Atherosclerosis
- A Study of the Onset and Offset of Antiplatelet Effects Comparing AZD6140, Clopidogrel, and Placebo With Aspirin
ClinicalTrials.gov Identifier: NCT00528411 - Recruiting
Coronary Artery Disease
- Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache
ClinicalTrials.gov Identifier: NCT00471952 - Recruiting
Migraine With Aura; Migraine Without Aura
- Randomized Trials of Vitamin Supplements and Eye Disease
ClinicalTrials.gov Identifier: NCT00000161 - Active, not recruiting
Macular Degeneration; Cataract
- Does Caffeine Reduce Rosuvastatin-Induced Protection Against Ischemia-Reperfusion Injury?
ClinicalTrials.gov Identifier: NCT00457652 - Recruiting
Ischemia Reperfusion Injury
- Prevention of Atherosclerosis and Heart Disease in Patients with Systemic Lupus Erythematosis (SLE)
ClinicalTrials.gov Identifier: NCT00054938 - Active, not recruiting
Systemic Lupus Erythematosus; Lupus
- Randomized Trial of Aspirin and Cataracts in U.S. Physicians
ClinicalTrials.gov Identifier: NCT00000157 - Completed
Cataract
- Administration Time-Dependent Antihypertensive Effects of Low Dose Aspirin in Well-Controlled Hypertensive Patients
ClinicalTrials.gov Identifier: NCT00386529 - Recruiting
Well-Controlled Hypertension
- The Study on Profile and Genetic Factors of Aspirin Resistance (ProGEAR Study)
ClinicalTrials.gov Identifier: NCT00250380 - Recruiting
Coronary Disease; Cerebral Infarction; Ischemic Attack, Transient
- The Effect of Serum LDL Lowering on Aspirin Resistance
ClinicalTrials.gov Identifier: NCT00466154 - Completed
Aspirin Resistance; Hypercholesterolemia
- Randomized Trial of Beta-Carotene and Macular Degeneration
ClinicalTrials.gov Identifier: NCT00000152 - Active, not recruiting
Macular Degeneration
- Does Caffeine Help Children With Obstructive Sleep Apnea Recover Faster From Anesthesia and With Less Complication After Tonsillectomy and Adenoidectomy?
ClinicalTrials.gov Identifier: NCT00273754 - Recruiting
Sleep Apnea, Obstructive; Tonsillectomy and Adenoidectomy; Postoperative Complications
- Esomeprazole With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett's Metaplasia
ClinicalTrials.gov Identifier: NCT00357682 - Recruiting
Esophageal Cancer; Precancerous/Nonmalignant Condition
- Esomeprazole With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett Esophagus
ClinicalTrials.gov Identifier: NCT00474903 - Recruiting
Esophageal Cancer; Precancerous/Nonmalignant Condition
- A Study of the Efficacy and Safety of Enteric-Coated Aspirin in Patients at Moderate Risk of Cardiovascular Disease
ClinicalTrials.gov Identifier: NCT00501059 - Recruiting
Moderate Risk of CVD
- Adjunctive Drug Treatment for Ischemic Stroke Patients
ClinicalTrials.gov Identifier: NCT00061373 - Recruiting
Cerebrovascular Accident
- Aspirin and Enalapril in Microalbuminuric Type 2 Diabetes Mellitus Patients
ClinicalTrials.gov Identifier: NCT00427271 - Recruiting
Diabetes Mellitus; Microalbuminuria
- Aspirin for the Prevention of Recurrent Venous Thromboembolism and Cardiovascular Events
ClinicalTrials.gov Identifier: NCT00222677 - Recruiting
Venous Thromboembolism; Deep Venous Thrombosis; Pulmonary Embolism; Atherosclerosis
- A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00384865 - Recruiting
Hypertension, Pulmonary
- Aspirin for Treatment of Multiple Sclerosis-Related Fatigue
ClinicalTrials.gov Identifier: NCT00467584 - Recruiting
Multiple Sclerosis
- Caffeine and Intermittent Claudication
ClinicalTrials.gov Identifier: NCT00388128 - Recruiting
Intermittent Claudication
- Effects of ASA on Prostate Tissue
ClinicalTrials.gov Identifier: NCT00234299 - Recruiting
Prostate Cancer
- The Effect of Low Dose Aspirin on the Pharmacokinetics of Methotrexate
ClinicalTrials.gov Identifier: NCT00464997 - Not yet recruiting
Rheumatoid Arthritis
- Secondary Prevention of Small Subcortical Strokes (SPS3) Trial
ClinicalTrials.gov Identifier: NCT00059306 - Recruiting
Cerebrovascular Accident; Hypertension
- Green Tea Extract (Polyphenon® E) and Low-Dose Aspirin in Preventing Cancer in Women at High Risk For Developing Breast Cancer
ClinicalTrials.gov Identifier: NCT00074061 - No longer recruiting
Breast Cancer
- Cilostazol in Acute Ischemic Stroke Treatment (CAIST)
ClinicalTrials.gov Identifier: NCT00272454 - Recruiting
Cerebral Infarction
- Laboratory Aspirin Resistance in Diabetics and Non-Diabetics
ClinicalTrials.gov Identifier: NCT00563875 - Recruiting
Drug Resistance
- Resistance to Aspirin and/or Clopidogrel Among Patients With PAD.
ClinicalTrials.gov Identifier: NCT00262561 - Recruiting
Intermittent Claudication
- Aspirin in Preventing Colorectal Cancer in Patients at Increased Risk of Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00468910 - Recruiting
Colorectal Cancer; Precancerous/Nonmalignant Condition
- Comparison of Awakening Versus Bedtime Dosing of Aspirin in Pre-Hypertension or Mild Essential Hypertension
ClinicalTrials.gov Identifier: NCT00449618 - Recruiting
High-Normal Blood Pressure; Mild Essential Hypertension
- A Study of the Effects of Inhibiting Platelet Function on Circulating Cancer Cells in Breast Cancer Patients
ClinicalTrials.gov Identifier: NCT00263211 - Recruiting
Breast Neoplasms
- Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence
ClinicalTrials.gov Identifier: NCT00495183 - Not yet recruiting
Cocaine Dependence
- Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction(SACCESS) Randomized, Double-Blind, Aspirin-Controlled Trial
ClinicalTrials.gov Identifier: NCT00129805 - Completed
Cerebral Infarction
- CVD Risk and Prevention in Early Glucose Intolerance
ClinicalTrials.gov Identifier: NCT00122447 - Recruiting
Impaired Glucose Tolerance (IGT)
- The Effect of Caffeine in Elderly Citizens
ClinicalTrials.gov Identifier: NCT00117520 - Completed
Healthy elderly citizens
- Caffeine in the Prevention of Post-Operative Nausea and Vomiting
ClinicalTrials.gov Identifier: NCT00130026 - Completed
POSTOP NAUSEA VOMITING
- Warfarin Versus Aspirin Recurrent Stroke Study
ClinicalTrials.gov Identifier: NCT00027066 - Completed
Stroke
- Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00152724 - Recruiting
Healthy volunteers
- Low Dose Aspirin and Statins for Primary Prevention of Atherosclerosis and Arterial Thromboembolism in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00371501 - Recruiting
Atherosclerosis; Thromboembolism; Systemic Lupus Erythematosus
- Caffeine for Excessive Daytime Somnolence in Parkinson's Disease
ClinicalTrials.gov Identifier: NCT00459420 - Recruiting
Parkinson's Disease; Excessive Daytime Somnolence
- Does Aspirin Have a Protective Role Against Chemotherapeutically Induced Ototoxicity?
ClinicalTrials.gov Identifier: NCT00578760 - Not yet recruiting
Hearing Loss; Ototoxicity
- Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting: The PAPA CABG Study
ClinicalTrials.gov Identifier: NCT00330772 - Recruiting
Coronary Artery Disease; Coronary Artery Bypass Grafting
- Aspirin Prophylaxis in Sickle Cell Disease
ClinicalTrials.gov Identifier: NCT00178464 - Recruiting
Sickle Cell Disease
- Aspirin in Patients With Myocardial Infarction and Thrombocytopenia
ClinicalTrials.gov Identifier: NCT00501345 - Recruiting
Thrombocytopenia; Myocardial Infarction
- ASCEND: A Study of Cardiovascular Events iN Diabetes
ClinicalTrials.gov Identifier: NCT00135226 - Recruiting
Type 1 Diabetes Mellitus; Type 2 Diabetes Mellitus
- A Study of Aspirin and Clopidogrel in Patients with Idiopathic Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00105209 - Completed
Hypertension, Pulmonary
- TRIAL OF ASPIRIN AND ARGININE RESTRICTION IN FAMILIAL COLON CANCER
ClinicalTrials.gov Identifier: NCT00578721 - Not yet recruiting
Colon Cancer
- Cilostazol in Acute Ischemic Stroke Treatment (CAIST)
ClinicalTrials.gov Identifier: NCT00272129 - Not yet recruiting
Cerebral Infarction
- Intravenous Pantoloc In Aspirin-Induced Ulcer Bleeding
ClinicalTrials.gov Identifier: NCT00153725 - Completed
Cardiovascular Disease; Cerebrovascular Disorders
- Experimental Studies of the Effects of Caffeine on Glucose Regulation
ClinicalTrials.gov Identifier: NCT00432887 - Completed
Diabetes Mellitus, Type 2
- Effects of Low Doses of Caffeine on Mood, Physiology and Mental Function
ClinicalTrials.gov Identifier: NCT00487227 - Completed
Healthy
- Aspirin in Treating Patients With Dukes Stage C or High-Risk Dukes Stage B Colorectal Cancer That Has Been Completely Removed by Surgery
ClinicalTrials.gov Identifier: NCT00565708 - Not yet recruiting
Colorectal Cancer
- Study of Aspirin and TPA in Acute Ischemic Stroke
ClinicalTrials.gov Identifier: NCT00417898 - Not yet recruiting
Acute Ischemic Stroke
- ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial
ClinicalTrials.gov Identifier: NCT00161070 - Completed
Brain Ischemia; TIA (Transient Ischemic Attack); Prevention & Control; Arteriosclerosis
- Effects of Kava on the Body's Elimination of Caffeine and Dextromethorphan
ClinicalTrials.gov Identifier: NCT00009542 - Completed
Healthy
- Platelet Inhibition by Aspirin, Acetaminophen and NSAID
ClinicalTrials.gov Identifier: NCT00536068 - Completed
Hemostasis
- Determining the Risk Factors such as Smoking, Alcohol, and Caffeine and their Association with Osteoporosis in Men
ClinicalTrials.gov Identifier: NCT00011323 - Completed
Osteoporosis
- 12-Week No-Rofecoxib Plus Aspirin Endoscopy Study
ClinicalTrials.gov Identifier: NCT00543465 - Completed
Arthritis, Rheumatoid; Osteoarthritis
- Celecoxib, Ibuprofen and the Antiplatelet Effect of Aspirin
ClinicalTrials.gov Identifier: NCT00565500 - Completed
Ischemic Heart Disease; Osteoarthritis
- Aspirin-Myocardial Infarction Study (AMIS)
ClinicalTrials.gov Identifier: NCT00000491 - Completed
Cardiovascular Diseases; Coronary Disease; Heart Diseases; Myocardial Infarction; Myocardial Ischemia
- To Compare the Gastroprotective Effects and Pharmacokinetic Profile of PA Versus Enteric-Coated Aspirin
ClinicalTrials.gov Identifier: NCT00442052 - Completed
Healthy
- Are Aspirin, Warfarin, and Clopidogrel Equally Effective in the Treatment of Patients With Symptomatic CHF and Reduced Ejection Fraction?
ClinicalTrials.gov Identifier: NCT00007683 - Completed
NYHA Class II, III or IV CHF; Left ventricular ejection fraction less than or equal to 35%
- Effect of Fluvastatin on Top of Clopidogrel and Aspirin in Patients After DES Implantation on Platelet Aggregation
ClinicalTrials.gov Identifier: NCT00465322 - Completed
Drug-Interactions
- AGN 201904 Versus Esomeprazole in the Prevention of Aspirin-Induced Stomach or Upper Intestinal Damage in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00325715 - Completed
Peptic Ulcer
- Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury?
ClinicalTrials.gov Identifier: NCT00430170 - Completed
Cardiovascular Disease; Ischemia-Reperfusion Injury

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