Azelaic Acid Topical |
Azelex; Finacea; Finevin |
Azelaic acid Chemical name nonanedioic acid Other names 1,7-heptanedicarboxylic acid Chemical formula C9H16O4 Molecular mass 188.22 g/mol CAS number [123-99-9] Melting point 98-103 °C Boiling point 237 °C at 20 mmHg SMILES OC(CCCCCCCC(O)=O)=O Disclaimer and references Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast tha ...
Wikipedia - [full article]
Azelaic Acid Topical Clinical Trials
- Comparison of efficacy and safety of Azelaic Acid 15% gel with its vehicle in subjects with mild to moderate acne.
ClinicalTrials.gov Identifier: NCT00031096 - Completed
Acne
- A Study of Azelaic Acid (AzA) 15% in Topical Treatment of Mild to Moderate Perioral Dermatitis
ClinicalTrials.gov Identifier: NCT00403949 - Completed
Perioral Dermatitis
- Photodynamic Therapy Using Topical Aminolevulinic Acid in Treating Patients With Actinic Keratosis
ClinicalTrials.gov Identifier: NCT00524485 - Recruiting
Precancerous/Nonmalignant Condition
- A Study of Azelaic Acid (AzA) 15% Gel in the Treatment of Seborrheic Dermatitis of the Face
ClinicalTrials.gov Identifier: NCT00408330 - Completed
Seborrheic Dermatitis on the Face
- Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer
ClinicalTrials.gov Identifier: NCT00296036 - Recruiting
Breast Cancer; Drug Toxicity; Unspecified Adult Solid Tumor, Protocol Specific
- Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo
ClinicalTrials.gov Identifier: NCT00342303 - Active, not recruiting
Fatty Acid Metabolism
- A study to compare the efficacy of intravenous loading doses followed by maintenance treatment with oral ibandronic acid versus zoledronic acid in patients with skeletal metastases experiencing moderate to severe pain.
ClinicalTrials.gov Identifier: NCT00099177 - Active, not recruiting
Pain; Bone Neoplasms; Neoplasm Metastasis
- Does Topical Steroid Treatment Impair the Adrenal Function?
ClinicalTrials.gov Identifier: NCT00476489 - Recruiting
Hypothalamus-Pituitary-Adrenal Axis Assessement; Topical Steroid Therapy in Chronic Skin Diseases
- A study to compare the efficacy of intravenous loading doses followed by maintenance treatment with intravenous ibandronic acid versus zoledronic acid in patients with skeletal metastases experiencing moderate to severe pain.
ClinicalTrials.gov Identifier: NCT00099203 - Active, not recruiting
Pain; Bone Neoplasms; Neoplasm Metastasis
- Relationship Between Folic Acid and Warfarin Metabolism and Effect
ClinicalTrials.gov Identifier: NCT00162409 - Recruiting
Folic Acid Deficiency
- DHA (Docosahexaenoic Acid), an Omega 3 Fatty Acid, in Slowing the Progression of Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00440050 - Active, not recruiting
Alzheimer's Disease
- Double-Blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)
ClinicalTrials.gov Identifier: NCT00145327 - Active, not recruiting
Osteoporosis
- Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults
ClinicalTrials.gov Identifier: NCT00480207 - Recruiting
Depression
- On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication
ClinicalTrials.gov Identifier: NCT00161096 - Active, not recruiting
Chronic Use of Acid Suppressive Medication; GORD; GERD; Reflux; Peptic Ulcer
- Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes
ClinicalTrials.gov Identifier: NCT00567528 - Recruiting
Soft Tissue Injuries; Comparison of Topical and Oral Ibuprofen
- Study to Compare the Acne Relapse Rate of Oral Minocycline to Oral Minocycline in Combination With Topical Tretinoin, Followed by Topical Tretinoin Alone
ClinicalTrials.gov Identifier: NCT00240513 - Recruiting
Acne Vulgaris
- Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer
ClinicalTrials.gov Identifier: NCT00045006 - Active, not recruiting
Cancer
- Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)
ClinicalTrials.gov Identifier: NCT00000621 - Active, not recruiting
Emphysema; Lung Diseases; Lung Diseases, Obstructive; Chronic Obstructive Pulmonary Disease
- Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress
ClinicalTrials.gov Identifier: NCT00014027 - Recruiting
Healthy
- Efficacy and Safety of Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women with Osteopenia, 45 Years of Age and Older.
ClinicalTrials.gov Identifier: NCT00132808 - Active, not recruiting
Osteopenia (osteoporosis prevention)
- Randomized Phase Iii-Study On Valproic Acid In Combination With All-Trans Retinoic Acid, Standard Induction- And Consolidation Therapy In Older Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00151255 - Recruiting
Acute myeloid leukemia, age > 60 years
- Comparison of the Gastric Acid Suppressive Effects of Esomeprazole and Generic Omeprazole
ClinicalTrials.gov Identifier: NCT00542347 - Recruiting
Gastric Acid
- The Effect of Folic Acid on Efficacy of Sulfadoxine-Pyrimethamine in Pregnant Women in Western Kenya
ClinicalTrials.gov Identifier: NCT00130065 - Active, not recruiting
Malaria
- Randomized Phase Ii-Study On Valproic Acid, All-Trans Retinoic Acid And Their Combination In Induction And Consolidation Therapy As Well As Pegfilgrastim After Consolidation Therapy In Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00151242 - Recruiting
Acute Myeloid Leukemia
- A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Solid Tumors
ClinicalTrials.gov Identifier: NCT00127127 - Active, not recruiting
Tumors
- Controlled Trial of 4-Aminosalicylic Acid in Patients with Small Bowel Crohn's Disease
ClinicalTrials.gov Identifier: NCT00004423 - Active, not recruiting
Crohn's Disease
- Study of Docosahexaenoic Acid (DHA) Supplementation in Patients with X-Linked Retinitis Pigmentosa
ClinicalTrials.gov Identifier: NCT00004827 - Active, not recruiting
Retinitis Pigmentosa
- Topical Amethocaine Gel for Intramuscular Injection in Term Neonates
ClinicalTrials.gov Identifier: NCT00267111 - Active, not recruiting
Pain
- An Investigational Drug Study with Suberoylanilide Hydroxamic Acid in Relapsed Diffuse Large B-cell Lymphoma
ClinicalTrials.gov Identifier: NCT00097929 - Active, not recruiting
B-Cell Lymphoma
- An Imaging Trial of the Distribution of Topical Gel Formulations in the Human Vagina
ClinicalTrials.gov Identifier: NCT00214747 - Active, not recruiting
HIV Infections
- Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss
ClinicalTrials.gov Identifier: NCT00418730 - Active, not recruiting
Androgenetic Alopecia
- A Study to Determine the Optimal Tolerated Regime and Safety of PEP005 Topical Gel
ClinicalTrials.gov Identifier: NCT00427050 - Active, not recruiting
Actinic Keratoses
- Safety and Efficacy Trial with Zoledronic Acid for the Treatment of Paget's Disease of Bone
ClinicalTrials.gov Identifier: NCT00103740 - Active, not recruiting
Paget's Disease of Bone
- Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in Infants
ClinicalTrials.gov Identifier: NCT00004410 - Recruiting
Cholestasis
- A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Malignant Lymphoma
ClinicalTrials.gov Identifier: NCT00127140 - Active, not recruiting
Malignant Lymphoma
- Suberoylanilide Hydroxamic Acid in Treating Patients With Relapsed Non-Hodgkin''s Lymphoma
ClinicalTrials.gov Identifier: NCT00124631 - Active, not recruiting
recurrent adult diffuse large cell lymphoma
- High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed
ClinicalTrials.gov Identifier: NCT00002650 - Active, not recruiting
Rectal Cancer; prevention of colorectal cancer; Colon Cancer
- Omega-3 Fatty Acid Status in Morbid Obesity Before and After Surgical Treatment
ClinicalTrials.gov Identifier: NCT00558532 - Recruiting
Morbid Obesity; Cardiovascular Disease; Fatty Acid Levels
- A Phase 4 Trial Assessing CLOBEX Spray, 0.05% When Used as Monotherapy or as Add-on Therapy to Existing Systemic or Topical Anti-Psoriatic Agents.
ClinicalTrials.gov Identifier: NCT00437216 - Active, not recruiting
Psoriasis
- Suberoylanilide Hydroxamic Acid and Capecitabine in Treating Patients with Metastatic Or Unresectable Solid Tumors
ClinicalTrials.gov Identifier: NCT00121277 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Ketoprofen Topical Patch, 20% in the Treatment of Pain Associated With Osteoarthritis Flare of the Knee
ClinicalTrials.gov Identifier: NCT00365586 - Active, not recruiting
Osteoarthritis
- Valproic Acid in Treating Patients With Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00075777 - Active, not recruiting
recurrent Kaposi's sarcoma; epidemic Kaposi's sarcoma
- Lactic Acid in the Rectum and Life-Threatening Infection.
ClinicalTrials.gov Identifier: NCT00197938 - Recruiting
Septic Shock
- Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy
ClinicalTrials.gov Identifier: NCT00005634 - Active, not recruiting
Leukemia; Lymphoma; Prostate Cancer; Multiple Myeloma; Eye Cancer
- Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail
ClinicalTrials.gov Identifier: NCT00443820 - Active, not recruiting
Onychomycosis
- Efficacy, Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail
ClinicalTrials.gov Identifier: NCT00443898 - Active, not recruiting
Onychomycosis
- Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants
ClinicalTrials.gov Identifier: NCT00433485 - Active, not recruiting
Neoplastic Syndrome; Non-Melanomatous Skin Cancer
- A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand
ClinicalTrials.gov Identifier: NCT00544297 - Active, not recruiting
Actinic Keratosis
- Safety and Efficacy Trial of the Use of A-007 Topical Gel in the Treatment of HSIL of the Cervix
ClinicalTrials.gov Identifier: NCT00285207 - Active, not recruiting
Cervical Intraepithelial Neoplasia; Uterine Cervical Dysplasia
- Topical Sunscreen in Preventing Skin Rash in Patients Receiving Drugs Such as Erlotinib or Cetuximab for Cancer
ClinicalTrials.gov Identifier: NCT00362986 - Active, not recruiting
Dermatologic Complications; Unspecified Adult Solid Tumor, Protocol Specific
- Dimethylxanthenone Acetic Acid in Treating Patients With Solid Tumors
ClinicalTrials.gov Identifier: NCT00003697 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Pilot Study to Evaluate Nucleic Acid Amplification Methods in the Diagnosis and Management of Active TB
ClinicalTrials.gov Identifier: NCT00023439 - Recruiting
Tuberculosis
- Efficacy, Safety and Tolerability of Topical 10% Terbinafine Hydrogen Chloride Versus 5% Amorolfine Nail Lacquer in Patients With Mild to Moderate Toenail Onychomycosis
ClinicalTrials.gov Identifier: NCT00459537 - Active, not recruiting
Onychomycosis
- Study of Treatment and Metabolism in Patients With Urea Cycle Disorders
ClinicalTrials.gov Identifier: NCT00004307 - Recruiting
Amino Acid Metabolism, Inborn Errors
- Study of Zoledronic Acid for Patients With Hormone-Sensitive Bone Metastases From Prostate Cancer
ClinicalTrials.gov Identifier: NCT00242567 - Recruiting
Prostate Cancer
- Efficacy of a New Topical Anesthetic
ClinicalTrials.gov Identifier: NCT00562211 - Recruiting
Pain
- Suberoylanilide Hydroxamic Acid in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancer
ClinicalTrials.gov Identifier: NCT00132067 - Active, not recruiting
recurrent ovarian epithelial cancer; peritoneal cavity cancer
- Higher Frequency Zoledronic Acid in the Treatment of Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00263484 - Recruiting
Multiple Myeloma
- Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain
ClinicalTrials.gov Identifier: NCT00351104 - Active, not recruiting
Sprain; Strain
- Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis
ClinicalTrials.gov Identifier: NCT00352625 - Active, not recruiting
Tendonitis; Bursitis
- Topical Tacrolimus 0.03% Ointment for Intractable Allergic Conjunctivitis: An Open Label Pilot Study
ClinicalTrials.gov Identifier: NCT00443105 - Active, not recruiting
Allergic Conjunctivitis
- Painful HIV Neuropathy and Alpha-Lipoic Acid
ClinicalTrials.gov Identifier: NCT00079807 - Active, not recruiting
HIV; Peripheral Neuropathy
- A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris
ClinicalTrials.gov Identifier: NCT00421993 - Active, not recruiting
Acne Vulgaris
- Efficacy and Safety of Topical Bromfenac Ophthalmic Solution vs. Placebo in Subjects With Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00423007 - Active, not recruiting
Allergic Conjunctivitis
- Ursodesoxycholic Acid in the Treatment of Duodenal Adenomas in FAP Patients.
ClinicalTrials.gov Identifier: NCT00134758 - Recruiting
Adenomatous Polyposis Coli; Adenoma
- Study of Zoledronic Acid Administered Monthly Versus Every 3 Months in Multiple Myeloma and Breast Cancer Patients Who Were Treated With Zoledronic Acid the Prior Year
ClinicalTrials.gov Identifier: NCT00424983 - Recruiting
Multiple Myeloma; Breast Cancer
- Study of a New Dressing for Use With Topical Medications
ClinicalTrials.gov Identifier: NCT00234728 - Recruiting
Psoriasis
- Topical Agent for Treatment of Red Skin
ClinicalTrials.gov Identifier: NCT00279890 - Active, not recruiting
Rosacea; Bilaterally Symmetric Red Skin on Cheeks
- Clinical and Laboratory Study of Methylmalonic Acidemia
ClinicalTrials.gov Identifier: NCT00078078 - Recruiting
Amino Acid Metabolism; Inborn Errors
- Functional and Molecular Characterisation of Oesophageal Distal Epithelium: Correlations With Acid and Non Acid Reflux
ClinicalTrials.gov Identifier: NCT00231881 - Recruiting
Gastro-Oesophageal Reflux
- Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)
ClinicalTrials.gov Identifier: NCT00410566 - Recruiting
Acid Sphingomyelinase Deficiency; Niemann-Pick Disease
- Paclitaxel, Folic Acid, and Lometrexol in Treating Patients With Locally Advanced or Metastatic Solid Tumors
ClinicalTrials.gov Identifier: NCT00024310 - Active, not recruiting
Drug Toxicity; unspecified adult solid tumor, protocol specific
- Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora
ClinicalTrials.gov Identifier: NCT00312338 - Active, not recruiting
Bacterial Conjunctivitis
- Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer
ClinicalTrials.gov Identifier: NCT00132002 - Active, not recruiting
Male Breast Cancer; stage IV breast cancer; recurrent breast cancer
- The Effect of Fatty Acid Composition on Energy Intake and Satiety
ClinicalTrials.gov Identifier: NCT00242021 - Active, not recruiting
Obesity
- Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid
ClinicalTrials.gov Identifier: NCT00295646 - Active, not recruiting
Breast Cancer
- A Study of the Effect of Time on Topical Anesthetic Efficacy.
ClinicalTrials.gov Identifier: NCT00353041 - Recruiting
Pain
- New Topical Treatment for Continued Pain After Shingles
ClinicalTrials.gov Identifier: NCT00566904 - Recruiting
Postherpetic Neuralgia
- Suberoylanilide Hydroxamic Acid in Treating Patients With Metastatic and/or Locally Advanced or Locally Recurrent Thyroid Cancer
ClinicalTrials.gov Identifier: NCT00134043 - Active, not recruiting
follicular thyroid cancer; insular thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; Thyroid Cancer
- Aspirin and/or Folic Acid in Preventing Recurrent Colorectal Polyps
ClinicalTrials.gov Identifier: NCT00033319 - Active, not recruiting
prevention of colorectal cancer; Colon Cancer; Rectal Cancer
- Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors
ClinicalTrials.gov Identifier: NCT00107458 - Active, not recruiting
childhood brain tumor; childhood meningioma; childhood solid tumor; childhood spinal cord tumors
- 24 Month Extension to Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients(Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients
ClinicalTrials.gov Identifier: NCT00555789 - Recruiting
Kidney Transplantation
- Evaluation of Topical B12 for the Treatment of Childhood Atopic Dermatitis
ClinicalTrials.gov Identifier: NCT00465699 - Recruiting
Eczema
- Nicotinic Acid - Pharmacokinetics, Pharmacodynamics, Receptor Expression
ClinicalTrials.gov Identifier: NCT00176020 - Not yet recruiting
Nicotinic Acid; Flush Symptom; Pharmacodynamic; Pharmacokinetic
- D4T or Abacavir Plus Vitamin Enhancement (DAVE)
ClinicalTrials.gov Identifier: NCT00143702 - Recruiting
Elevated Lactic Acid
- Fatty Acid Binding Protein 2 (FABP2) Ancillary Proposal
ClinicalTrials.gov Identifier: NCT00256633 - Active, not recruiting
Type 2 Diabetes Mellitus
- Efficacy of Weekly Versus Daily Folic Acid Supplementation
ClinicalTrials.gov Identifier: NCT00394862 - Active, not recruiting
Neural Tube Defects
- A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers
ClinicalTrials.gov Identifier: NCT00351767 - Active, not recruiting
Diabetic Foot Ulcers
- Effect of Acid Reflux on Respiratory Physiology During Exercise in Athletes With GER-Response to Acid Suppression
ClinicalTrials.gov Identifier: NCT00444236 - Not yet recruiting
Exercise Triggered Asthma; Gastroesophageal Reflux
- Inhibition of Gastric Acid is the Key to Satisfactory Relief of Symptoms With Esomeprazole in NUD Patients
ClinicalTrials.gov Identifier: NCT00222131 - Active, not recruiting
Indigestion
- Topical Imiquimod in Treating Patients With Recurrent Paget's Disease of the Vulva
ClinicalTrials.gov Identifier: NCT00504023 - Recruiting
Vulvar Cancer
- Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis
ClinicalTrials.gov Identifier: NCT00004441 - Recruiting
Cystic Fibrosis
- Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy and Pharmacokinetics of Myozyme in Patients with Late-Onset Pompe Disease.
ClinicalTrials.gov Identifier: NCT00158600 - Active, not recruiting
Pompe Disease (Late-onset); Glycogen storage disease type II (GSD-II); Acid Maltase Deficiency Disease; Glycogenosis 2
- Suberoylanilide Hydroxamic Acid in Treating Patients With Relapsed or Refractory Advanced Hodgkin''s Lymphoma
ClinicalTrials.gov Identifier: NCT00132028 - Active, not recruiting
recurrent adult Hodgkin''s lymphoma; stage IV adult Hodgkin''s lymphoma; adult lymphocyte depletion Hodgkin''s lymphoma; ...
- Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months), in Renal Transplant Patients
ClinicalTrials.gov Identifier: NCT00403416 - Active, not recruiting
Kidney Transplantation
- PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS
ClinicalTrials.gov Identifier: NCT00439673 - Active, not recruiting
Myelodysplastic Syndromes
- Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule
ClinicalTrials.gov Identifier: NCT00579410 - Active, not recruiting
Esophagitis; Inflammation; Gastritis; Abdominal Pain; Heartburn
- The Purpose of This Study is to Determine Whether Topical Application of PEP005 is Safe for the Treatment of Common Wart(s)
ClinicalTrials.gov Identifier: NCT00546611 - Recruiting
Warts
- Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery
ClinicalTrials.gov Identifier: NCT00320619 - Active, not recruiting
Scoliosis; Kyphosis; Lordosis; Spondylitis; Spinal Stenosis
- An Imaging Trial of the Distribution of Topical Gel in the Human Vagina: Assessment of Bare Spots
ClinicalTrials.gov Identifier: NCT00214812 - Recruiting
HIV Infections

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