Indinavir |
Crixivan |
Indinavir Systematic (IUPAC) name 1-[2-hydroxy-4- [(2-hydroxy-2,3-dihydro- 1H-inden-1-yl) carbamoyl]-5-phenyl-pentyl]-4- (pyridin-3-ylmethyl)- N-tert-butyl-piperazine-2-carboxamide Identifiers CAS number 150378-17-9 ATC code J05AE02 PubChem 5362440 DrugBank APRD00069 Chemical data Formula C36H47N5O4 Mol. weight 613.79 g/mol Pharmacokinetic data Bioavailability ? Protein binding 60% Metabolism ? Half life 1.8 (± 0.4) hours Excretion ? ...
Wikipedia - [full article]
Indinavir Clinical Trials
- The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment
ClinicalTrials.gov Identifier: NCT00005118 - Active, not recruiting
HIV Infections
- Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00050180 - Active, not recruiting
Healthy; HIV Infections
- Safety and Effectiveness of Giving Indinavir Plus Stavudine Plus Lamivudine to HIV-Infected Children
ClinicalTrials.gov Identifier: NCT00000901 - Active, not recruiting
HIV Infections
- Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00006397 - Active, not recruiting
HIV Infections
- Ritonavir and Indinavir in Children Failing Other Anti-HIV Treatment
ClinicalTrials.gov Identifier: NCT00012519 - Active, not recruiting
HIV Infections
- A Study to Evaluate the Safety and Tolerance of Combination Anti-HIV Drug Therapy (Indinavir, Lamivudine, and Zidovudine) in HIV-Positive Pregnant Women and Their Infants
ClinicalTrials.gov Identifier: NCT00000944 - Active, not recruiting
HIV Infections; Pregnancy
- Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002451 - Active, not recruiting
HIV Infections
- A PK Study of a Combination of Indinavir, Ritonavir and Amprenavir
ClinicalTrials.gov Identifier: NCT00148785 - Recruiting
Antiretroviral drugs
- A Study on the Safety and Effectiveness of L-756423 Plus Indinavir in HIV-Positive Patients Who Have Previously Taken Indinavir
ClinicalTrials.gov Identifier: NCT00002452 - Completed
HIV Infections
- Pharmacokinetic Study of Indinavir Drug Levels When Boosted With Ritonavir in Thailand
ClinicalTrials.gov Identifier: NCT00197639 - Recruiting
HIV Infection
- Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice Daily
ClinicalTrials.gov Identifier: NCT00002241 - Active, not recruiting
HIV Infections
- Treatment with Interleukin-2 (IL-2) Plus Combination Anti-HIV-Drug Therapy (HAART) for Patients Formerly in ACTG 328
ClinicalTrials.gov Identifier: NCT00000923 - Active, not recruiting
HIV Infections
- Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection
ClinicalTrials.gov Identifier: NCT00001644 - Active, not recruiting
HIV Infection
- A Study of Indinavir Taken with or without DMP 266
ClinicalTrials.gov Identifier: NCT00002393 - Completed
HIV Infections
- A Comparison of Two Dose Levels of Indinavir Combined with Two Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs) in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002406 - Completed
HIV Infections
- A Comparison of 141W94 and Indinavir in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002202 - Completed
HIV Infections
- A Randomized Trial of the Efficacy and Safety of a Strategy of Starting with Nelfinavir Versus Ritonavir Added to Background Antiretroviral (AR) Nucleoside Therapy in HIV-Infected Individuals with CD4+ Cell Counts Less than or Equal to 200/mm3
ClinicalTrials.gov Identifier: NCT00000859 - Active, not recruiting
HIV Infections
- Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIV
ClinicalTrials.gov Identifier: NCT00027339 - Active, not recruiting
HIV Infections
- Safety and Tolerance of Indinavir plus Ritonavir in HIV-Positive Patients Failing Therapy with Amprenavir, Nelfinavir, or Saquinavir
ClinicalTrials.gov Identifier: NCT00001133 - Completed
HIV Infections
- Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002375 - Completed
HIV Infections
- Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males with Hemophilia
ClinicalTrials.gov Identifier: NCT00002386 - Completed
HIV Infections; Hemophilia A
- Paclitaxel in Treating Patients With AIDS-Related Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00003008 - Active, not recruiting
epidemic Kaposi's sarcoma; recurrent Kaposi's sarcoma
- A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001084 - Completed
HIV Infections
- Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination with Nucleoside Analogs: A Rollover Study for ACTG 320
ClinicalTrials.gov Identifier: NCT00000885 - Completed
HIV Infections
- The Effectiveness of Indinavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients with No Symptoms of Infection
ClinicalTrials.gov Identifier: NCT00002179 - Completed
HIV Infections
- A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive Patients
ClinicalTrials.gov Identifier: NCT00002236 - Completed
HIV Infections
- A Study of Ritonavir/Indinavir Combination in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002223 - Completed
HIV Infections
- A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 mg q 8 h Versus 1,200 mg q 12 h in Combination with Zidovudine and 3TC
ClinicalTrials.gov Identifier: NCT00002208 - Completed
HIV Infections
- Study of How Indinavir (an Anti-HIV Drug) and Rifabutin (a Drug Used to Treat MAC, an HIV-Associated Disease) Interact in HIV-Positive and HIV-Negative Adults
ClinicalTrials.gov Identifier: NCT00000877 - Completed
HIV Infections
- Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success with Nelfinavir
ClinicalTrials.gov Identifier: NCT00002220 - Completed
HIV Infections
- The Anti-HIV Effects of Saquinavir Soft Gelatin Capsules Versus Indinavir in Patients Who Have Used Saquinavir Hard Gelatin Capsules for One Year
ClinicalTrials.gov Identifier: NCT00000848 - Completed
HIV Infections
- A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors
ClinicalTrials.gov Identifier: NCT00002235 - Completed
HIV Infections
- Virologic and Immunologic Activity of Continued Lamivudine (3TC) vs Delavirdine (DLV) in Combination with Indinavir (IDV) and Zidovudine (ZDV) or Stavudine (d4T) in 3TC-Experienced Subjects
ClinicalTrials.gov Identifier: NCT00000882 - Completed
HIV Infections
- Addition of Efavirenz or Nelfinavir to a Lamivudine/Zidovudine/Indinavir HIV Treatment Regimen
ClinicalTrials.gov Identifier: NCT00000903 - Completed
HIV Infections
- A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More Months
ClinicalTrials.gov Identifier: NCT00000841 - Completed
HIV Infections
- The Safety and Effectiveness of Indinavir Sulfate Plus Efavirenz
ClinicalTrials.gov Identifier: NCT00002387 - Completed
HIV Infections
- The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined with Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002379 - Completed
HIV Infections
- A Study of Indinavir Sulfate Given Together with Stavudine to HIV-Positive Patients
ClinicalTrials.gov Identifier: NCT00002354 - Completed
HIV Infections
- A Study to Compare the Safety and Effectiveness of Indinavir Combined with Stavudine and Lamivudine
ClinicalTrials.gov Identifier: NCT00002424 - Suspended
HIV Infections
- A Study of Abacavir Plus Indinavir Sulfate Plus Efavirenz in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001086 - Completed
HIV Infections
- A Pilot Study of Autologous T-Cell Transplantation with Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas
ClinicalTrials.gov Identifier: NCT00001566 - Recruiting
Ewing's Sarcoma; Rhabdomyosarcoma
- A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV Infection
ClinicalTrials.gov Identifier: NCT00006154 - Not yet recruiting
HIV Infections
- The Addition of Indinavir to Anti-HIV Treatment in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00000861 - Terminated
HIV Infections
- Autologous T-Cell Transplantation, Vaccine Therapy, and Indinavir in Treating Patients With Metastatic Pediatric Sarcomas
ClinicalTrials.gov Identifier: NCT00019266 - Completed
Sarcoma
- A Study of Indinavir Plus Ritonavir Plus Two NRTIs vs. Nelfinavir Plus Two NRTIs in HIV Positive Patients
ClinicalTrials.gov Identifier: NCT00541463 - Completed
HIV Infections
- A Study of 141W94 in Combination with Other Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002372 - Completed
HIV Infections
- A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations
ClinicalTrials.gov Identifier: NCT00002430 - Completed
HIV Infections
- A Study of L-735,524 in HIV-Positive Children and Adolescents
ClinicalTrials.gov Identifier: NCT00002351 - Completed
HIV Infections
- A Study of Three Different Anti-HIV Drug Combinations in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002410 - Completed
HIV Infections
- A Study of Two Anti-HIV Drug Combinations in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002400 - Completed
HIV Infections
- A Comparison of Two Anti-HIV Triple-Drug Combinations in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002168 - Completed
HIV Infections
- The Effectiveness of GM-CSF in HIV-Positive Patients Who Are Also Receiving Anti-HIV Therapy
ClinicalTrials.gov Identifier: NCT00000850 - Completed
HIV Infections
- A Comparison of Epivir Plus Crixivan Combined with Zerit or Retrovir in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002369 - Completed
HIV Infections
- A Study of Three Drug Combination Therapies in HIV-Infected Patients Who Have Never Been Treated with Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002407 - Completed
HIV Infections
- Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment with Protease Inhibitors
ClinicalTrials.gov Identifier: NCT00002361 - Completed
HIV Infections
- The Effectiveness of HIV RNA Viral Load Testing in Determining Treatment Type in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002376 - Completed
HIV Infections
- A Study of the Effectiveness of Different Anti-HIV Treatments in HIV-Positive Individuals Who Have Been on a Protease Inhibitor-Containing Drug Regimen for at Least 16 Weeks
ClinicalTrials.gov Identifier: NCT00000914 - Completed
HIV Infections
- The Effect of Milk Thistle on the Pharmacokinetics of Indinavir
ClinicalTrials.gov Identifier: NCT00011635 - Completed
HIV Infection; Healthy
- A Study of a Combination of Four Drugs in Patients with Recent HIV Infection
ClinicalTrials.gov Identifier: NCT00002233 - Completed
HIV Infections
- A Study of Three Anti-HIV Drug Combinations in Patients Who Have Taken Amprenavir
ClinicalTrials.gov Identifier: NCT00001095 - Completed
HIV Infections
- A Randomized Trial of L-735,524, An Inhibitor of the HIV Protease Enzyme, and Interleukin-2 in Persons Infected With HIV (NOTE: Only For Patients Who Previously Completed NIAID 93 CC-113)
ClinicalTrials.gov Identifier: NCT00000804 - Completed
HIV Infections
- A Study to Compare the Safety and Effectiveness of Two Dosing Schedules of Lamivudine in Combination with Two Other Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002442 - Completed
HIV Infections
- A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir
ClinicalTrials.gov Identifier: NCT00000892 - Completed
HIV Infections
- The Safety and Effectiveness of MK-639 and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002443 - Completed
HIV Infections
- A Study of Delavirdine Used Together with Other Anti-HIV Drugs in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002401 - Completed
HIV Infections
- A Study of 1592U89 in Combination with Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002440 - Completed
HIV Infections
- Comparison of New Anti-HIV Drug Combinations in HIV-Infected Children Who Have Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00001083 - Completed
HIV Infections
- Drug Interactions of Amprenavir and Efavirenz, in Combination with a Second Protease Inhibitor, in HIV-Negative Volunteers
ClinicalTrials.gov Identifier: NCT00005762 - Completed
HIV Infections
- A Study on Amprenavir in Combination with Other Anti-HIV Drugs in HIV-Positive Patients
ClinicalTrials.gov Identifier: NCT00000912 - Completed
HIV Infections
- A Study to Evaluate the Long-Term Effectiveness of Three Anti-HIV Drug Treatments in HIV-Positive Patients Who Have Never Been Exposed to Highly Active Antiretroviral Therapy (HAART)
ClinicalTrials.gov Identifier: NCT00000922 - Completed
HIV Infections
- Effectiveness of Anti-HIV Drugs in Patients Who Have Not Received Previous Anti-HIV Drugs During Different Stages of HIV Infection
ClinicalTrials.gov Identifier: NCT00006443 - Completed
HIV Infections
- Interactions Between HIV Protease Inhibitors and Calcium Channel Blockers
ClinicalTrials.gov Identifier: NCT00039975 - Completed
HIV Infections; Cardiovascular Diseases; Hypertension
- A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination with GM-CSF or IL-12 to HIV-Positive Patients
ClinicalTrials.gov Identifier: NCT00000896 - Completed
HIV Infections
- Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use with Certain Anti-HIV Drugs in HIV-Infected Women
ClinicalTrials.gov Identifier: NCT00016601 - Completed
HIV Infections
- Randomised Trial of Structured Treatment Interruption of HAART in HIV-Infected Adults in Abidjan (ANRS 1269 TRIVACAN)
ClinicalTrials.gov Identifier: NCT00158405 - Completed
HIV Infections
- A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
ClinicalTrials.gov Identifier: NCT00000919 - Completed
HIV Infections
- A Phase II Study of Intermittent Recombinant Human Interleukin-2 (rhIL-2) by Intravenous or Subcutaneous Administration in Subjects With HIV Infection on Highly Active Antiretroviral Therapy (HAART) Compared to HAART Alone
ClinicalTrials.gov Identifier: NCT00000870 - Completed
HIV Infections
- A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure
ClinicalTrials.gov Identifier: NCT00000918 - Completed
HIV Infections
- The Safety and Effectiveness of Lamivudine Plus Stavudine or Zidovudine in HIV-Infected Patients Who Have Taken Zidovudine
ClinicalTrials.gov Identifier: NCT00002371 - Completed
HIV Infections
- A Phase I /II Study of the Protease Inhibitor Indinavir (MK-0639) in Children with HIV Infection
ClinicalTrials.gov Identifier: NCT00001443 - Completed
Acquired Immunodeficiency Syndrome; HIV Infections
- A Phase III Randomized Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of 3TC/ZDV/1592U89 and 3TC/ZDV/IDV in HIV-1 Infected Antiretroviral Therapy-Naive Subjects.
ClinicalTrials.gov Identifier: NCT00002199 - Completed
HIV Infections
- Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected with HIV
ClinicalTrials.gov Identifier: NCT00001119 - Completed
HIV Infections
- A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients with AIDS
ClinicalTrials.gov Identifier: NCT00001058 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- A Six-Month Safety and Antiviral Study in HIV-1 Seropositive, AZT-Experienced Patients With CD4 Counts Less Than or Equal to 50 Cells/mm3 to Evaluate MK-639 Alone Versus Zidovudine (AZT) and 3TC Versus the Combination of MK-639 With AZT/3TC
ClinicalTrials.gov Identifier: NCT00002155 - Completed
HIV Infections
- A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir
ClinicalTrials.gov Identifier: NCT00002423 - Completed
HIV Infections
- Evaluation of Therapeutic Drug Monitoring of Protease Inhibitors On Virologic Success and Tolerance of HAART
ClinicalTrials.gov Identifier: NCT00122590 - Terminated
HIV Infections
- Efficacy and Tolerability of an Antiretroviral Bi-Therapy in HIV Infected Patients with Multidrug Resistance
ClinicalTrials.gov Identifier: NCT00120783 - Terminated
HIV Infections
- Treatment of Classical Non-HIV-Related Kaposi's Sarcoma With the Antiviral Drug Indinavir
ClinicalTrials.gov Identifier: NCT00362310 - Terminated
Classical Kaposi's Sarcoma
- Safety and Effectiveness of 3 Anti-HIV Treatments in Patients Who Have Failed Previous Treatments Containing Nelfinavir
ClinicalTrials.gov Identifier: NCT00006326 - Terminated
HIV Infections
- Controlled Clinical Trial of Antiviral Cytotoxic T Lymphocyte (CTL) Infusion Following Combination Antiretroviral Drug Therapy for Asymptomatic HIV-1 Infection
ClinicalTrials.gov Identifier: NCT00000875 - Terminated
HIV Infections
- Safety and Effectiveness of an Anti-HIV Drug Combination With and Without Hydroxyurea in Patients With Early HIV Infection
ClinicalTrials.gov Identifier: NCT00006339 - Terminated
HIV Infections
- A Study of the Safety and Effectiveness of Hydroxyurea in Patients on Potent Antiretroviral Therapy and Who Have Less Than 200 Copies/ml of HIV RNA in Their Blood
ClinicalTrials.gov Identifier: NCT00000916 - Terminated
HIV Infections

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