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A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Solid Tumors - Article


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Valproic Acid Injection

Depacon; Valproate Sodium


Clinical Trial: A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Solid Tumors

This study is currently recruiting patients.
Verified by Merck August 2005

Sponsored by: Merck
Information provided by: Merck
ClinicalTrials.gov Identifier: NCT00127127

Purpose

The primary purpose of this trial is to determine the maximum tolerated dose (MTD), or the maximum acceptable dose (MAD) and evaluate the dose limiting toxicity (DLT) of oral suberoylanilide hydroxamic acid in patients with solid tumors.
Condition Intervention Phase
Tumors
  Drug: MK0683, Suberoylanilide hydroxamic acid (SAHA)
 Phase I

MedlinePlus related topics:  Cancer;   Cancer Alternative Therapies

Study Type: Interventional
Study Design: Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety Study

Eligibility

Ages Eligible for Study:  20 Years   -   75 Years,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

Exclusion Criteria:

  • Patients with history of immunotherapy, radiotherapy, surgery, or chemotherapy during the previous 4 weeks; previous treatment is 5 or more chemotherapeutic regimens.
  • Any uncontrolled concomitant illness
  • Are pregnant or breast-feeding
  • Serious drug or food allergy

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00127127

Call For Information      +81-3-5203-8218 

Japan, Chuoku
      Call For Site Information, Tokyo,  Chuoku,  103-8416,  Japan; Recruiting

Study chairs or principal investigators

Medical Monitor,  Study Director,  Merck   

More Information

Study ID Numbers:  2005_040
Last Updated:  August 19, 2005
Record first received:  August 3, 2005
ClinicalTrials.gov Identifier:  NCT00127127
Health Authority: Japan: Ministry of Health, Labor and Welfare
ClinicalTrials.gov processed this record on 2005-08-23


Source: ClinicalTrials.gov
Cache Date: August 24, 2005

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Page Updated: June 1, 2005
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