Dexrazoxane Injection |
Zinecard |
Dexrazoxane hydrochloride (Zinecard®, Pharmacia) is a medication used to protect the heart against the cardiotoxic side effects of anthracycline chemotherapy. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known. This pharmacology-related article is a stub. You can help Wikipedia by expanding it. Retrieved from "http://en.wikipedia.org/wiki/Dexrazoxane" Categories: Pharmacology stubs ...
Wikipedia - [full article]
Dexrazoxane Injection Clinical Trials
- Vincristine, Doxorubicin, Cyclophosphamide and Dexrazoxane (VACdxr) With or Without ImmTher for Newly Diagnosed High Risk Ewing's Sarcoma
ClinicalTrials.gov Identifier: NCT00038142 - Recruiting
Ewing's Sarcoma
- Dexrazoxane and Cisplatin in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00550901 - Active, not recruiting
Unspecified Adult Solid Tumor, Protocol Specific
- Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone Sarcoma
ClinicalTrials.gov Identifier: NCT00544778 - Active, not recruiting
Sarcoma
- TLK286 (Telcyta) vs. Doxil/Caelyx or Hycamtin in Platinum Refractory or Resistant Ovarian Cancer
ClinicalTrials.gov Identifier: NCT00057720 - Active, not recruiting
Ovarian Neoplasms
- Penile Injection Anxiety
ClinicalTrials.gov Identifier: NCT00582231 - Recruiting
Penile Injection Therapy; Erectile Dysfunction; Radical Pelvic Surgery
- Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma
ClinicalTrials.gov Identifier: NCT00003937 - Completed
cardiac toxicity; localized osteosarcoma
- Safety of KAI-9803 for Injection with Angioplasty following Heart Attack
ClinicalTrials.gov Identifier: NCT00093197 - Active, not recruiting
Myocardial Infarction
- A Study to Evaluate the Effects of Two Vitamin D Analogs, Zemplar® Injection and Hectorol® Injection, on Intestinal Absorption of Calcium in Patients With Stage 5 Chronic Kidney Disease
ClinicalTrials.gov Identifier: NCT00257920 - Recruiting
Stage 5 Chronic Kidney Disease (CKD); Secondary Hyperparathyroidism
- Combination Chemotherapy and Radiation Therapy in Treating Children With Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00004034 - Active, not recruiting
L2 childhood acute lymphoblastic leukemia; untreated childhood acute lymphoblastic leukemia; cardiac toxicity; ...
- Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00002827 - Active, not recruiting
stage II childhood Hodgkin's disease; stage III childhood Hodgkin's disease; cardiac toxicity; stage I childhood Hodgkin's disease; ...
- Study of TLK199 HCl Liposomes for Injection in Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00035867 - Active, not recruiting
Myelodysplastic Syndromes
- Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors
ClinicalTrials.gov Identifier: NCT00039481 - Completed
cardiac toxicity; unspecified childhood solid tumor, protocol specific
- Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
ClinicalTrials.gov Identifier: NCT00548197 - Recruiting
Intravitreal Bevacizumab Injection; Pars Plana Vitrectomy; Tractional Retinal Detachment; Diabetic Retinopathy
- Adverse Drug Reactions of Different Brands of Ceftazidime Injection
ClinicalTrials.gov Identifier: NCT00173901 - Active, not recruiting
Infection
- Topical Amethocaine Gel for Intramuscular Injection in Term Neonates
ClinicalTrials.gov Identifier: NCT00267111 - Active, not recruiting
Pain
- Validation of Self-Reported Needle Sharing Among Injection Drug Users
ClinicalTrials.gov Identifier: NCT00341081 - Active, not recruiting
Viral Infection
- EPC by Intracoronary Injection in Patients With Chronic Stable Angina
ClinicalTrials.gov Identifier: NCT00384514 - Active, not recruiting
Coronary Artery Disease
- A Effectiveness and Safety Study of AQUAVAN® Injection (AQUAVAN; Fospropofol Disodium) for Sedation During Colonoscopy
ClinicalTrials.gov Identifier: NCT00125424 - Active, not recruiting
Colonoscopy; Colon Polyps; Endoscopic sedation; Endoscopic outcomes; Endoscopy
- The Necessity of an Injection-Meal-Interval in Patients With Type 2 Diabetes Mellitus and Therapy With Human Insulin
ClinicalTrials.gov Identifier: NCT00529165 - Recruiting
Diabetes Mellitus Type 2; Injection to Meal Time; Human Insulin
- Comparison Between Type A Botulinum Toxin Injection and Corticosteroid Injection in the Treatment of Tennis Elbow
ClinicalTrials.gov Identifier: NCT00395616 - Recruiting
Type A Botulinum Toxin; Tennis Elbow
- Safety and Effects of Implanted (Autologous) Skeletal Myoblasts (MyoCell) Using an Injection Catheter = SEISMIC Trial
ClinicalTrials.gov Identifier: NCT00375817 - Active, not recruiting
Myocardial Infarction; Heart Failure, Congestive
- Study of MEDI-522 Administered by Subcutaneous Injection to Adults With Plaque Psoriasis
ClinicalTrials.gov Identifier: NCT00192517 - Active, not recruiting
Psoriasis
- A 2-Year Study of Patients With Schizophrenia Who Are Treated With Long-Acting Risperidone Injection.
ClinicalTrials.gov Identifier: NCT00246194 - Active, not recruiting
Schizophrenia
- IOP Reduction After Anecortave Acetate Injection in Glaucoma Patients
ClinicalTrials.gov Identifier: NCT00533962 - Active, not recruiting
Glaucoma; Intraocular Pressure
- Behavioral Intervention for HIV and HCV-Uninfected Injection Drug Users
ClinicalTrials.gov Identifier: NCT00164372 - Active, not recruiting
HIV Infections; Hepatitis C
- Comparison of Efficacy Between Silicone Ahmed Glaucoma Valves With and Without Intravitreal Triamcinolone Injection
ClinicalTrials.gov Identifier: NCT00491712 - Active, not recruiting
Neovascular Glaucoma
- A Trial to Reduce Hepatitis C Among Injection Drug Users - 1
ClinicalTrials.gov Identifier: NCT00218192 - Active, not recruiting
HCV Negative Status; HCV Risk Behavior
- A Phase I/II Study of Chondrogen Delivered by Intra-Articular Injection Following Meniscectomy
ClinicalTrials.gov Identifier: NCT00225095 - Active, not recruiting
Recovery Following Partial Medial Meniscectomy
- Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00361842 - Active, not recruiting
Colorectal Neoplasms
- Intrathecal and Systemic Chemotherapy Combined With Radiation Therapy in Treating Young Patients With Newly Diagnosed Central Nervous System Atypical Teratoid/Rhabdoid Tumors
ClinicalTrials.gov Identifier: NCT00084838 - Recruiting
childhood rhabdoid tumor of the central nervous system
- Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00005578 - Completed
stage II childhood Hodgkin's disease; stage III childhood Hodgkin's disease; stage IV childhood Hodgkin's disease; cardiac toxicity; ...
- Doxorubicin HCI Liposome Injection Versus Weekly Docetaxel in Patients First Relapse Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00193037 - Active, not recruiting
Breast Cancer
- Vitamin K Injections for the Treatment of Painful Menstruation
ClinicalTrials.gov Identifier: NCT00104546 - Active, not recruiting
Dysmenorrhea
- Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma
ClinicalTrials.gov Identifier: NCT00077285 - Recruiting
childhood rhabdomyosarcoma; childhood soft tissue sarcoma; Muscle Cancer
- Injection Of AJCC Stage IIB, IIC, III And IV Melanoma Patients With A Multi-Epitope Peptide Vaccine Using GM-CSF DNA As An Adjuvant: A Pilot Trial To Assess Safety And Immunity
ClinicalTrials.gov Identifier: NCT00580060 - Active, not recruiting
Melanoma
- A Clinical Trial on Topotect® (Dexrazoxane) in the Treatment of Accidental Extravasation of Anthracyclines
ClinicalTrials.gov Identifier: NCT00548704 - Completed
Extravasation
- Efficacy of TopotectTM (Dexrazoxane) for Accidental Extravasation of Anthracyclines
ClinicalTrials.gov Identifier: NCT00548561 - Completed
Anthracycline Extravasation
- Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Injection Drug Users
ClinicalTrials.gov Identifier: NCT00004740 - Active, not recruiting
Tuberculosis
- Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads
ClinicalTrials.gov Identifier: NCT00054951 - Active, not recruiting
Hepatocellular Carcinoma
- Study of Pasireotide Long Acting Release (LAR) Injection in Patients With Acromegaly and Patients With Carcinoid Disease
ClinicalTrials.gov Identifier: NCT00446082 - Active, not recruiting
Carcinoid Tumor; Acromegaly
- Patients Preference With Self-Injection: The PRISM Study
ClinicalTrials.gov Identifier: NCT00253396 - Recruiting
Bruises
- Safety and Efficacy of PolyHeme(R) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-Hospital Setting
ClinicalTrials.gov Identifier: NCT00076648 - Active, not recruiting
Hemorrhagic Shock
- Fluocinolone Acetonide Implant Compared to Sham Injection in Patients With Diabetic Macular Edema
ClinicalTrials.gov Identifier: NCT00344968 - Active, not recruiting
Diabetic Macular Edema
- Injection Site Study In Patients With Type 2 Diabetes Mellitus (T2DM) And Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00394030 - Active, not recruiting
Type 2 Diabetes Mellitus
- Study of Taxoprexin Injection vs. Dacarbazine in Patients with Metastatic Malignant Melanoma
ClinicalTrials.gov Identifier: NCT00087776 - Active, not recruiting
Malignant Melanoma
- Insulin Glargine Injection Treatment in Place of Thiazolidinedione (TZD), Sulfonylurea, or Metformin in Triple Agent Therapy for Type 2 Diabetes Mellitus (T2DM) Adult Subjects With Unsatisfactory Control
ClinicalTrials.gov Identifier: NCT00283049 - Active, not recruiting
Diabetes Mellitus, Type 2
- Study of TPI 287 in Patients with Advanced Malignancies
ClinicalTrials.gov Identifier: NCT00113724 - Active, not recruiting
Neoplasms
- A Study to Determine the Effectiveness and Safety of Risperidone in the Prevention of Bipolar Mood Episodes
ClinicalTrials.gov Identifier: NCT00132678 - Active, not recruiting
Bipolar Disorder
- Azithromycin/Bicillin for treatment of early syphilis
ClinicalTrials.gov Identifier: NCT00031499 - Active, not recruiting
Syphilis
- Treating High Risk Leukemia with CD40 Ligand & IL-2 Gene Modified Tumor Vaccine.
ClinicalTrials.gov Identifier: NCT00058799 - Active, not recruiting
Leukemia
- Intraocular Pressure Immediately Following Intravitreous Injection of Ranibizumab
ClinicalTrials.gov Identifier: NCT00417703 - Recruiting
Choroidal Neovascularization
- Botulinum Toxin Injection for the Management of BPH
ClinicalTrials.gov Identifier: NCT00451191 - Recruiting
Benign Prostatic Hyperplasia
- Dysport® Injection in the Treatment of Chronic Lateral Epicondylitis
ClinicalTrials.gov Identifier: NCT00497913 - Recruiting
Tennis Elbow
- A Phase 2 open-label clinical study using intravenous Paxceed™ to treat patients with rheumatoid arthritis
ClinicalTrials.gov Identifier: NCT00055133 - Active, not recruiting
Rheumatoid Arthritis
- ATX-101 (Sodium Deoxycholate for Injection) for the Treatment of Superficial Lipomas
ClinicalTrials.gov Identifier: NCT00422188 - Recruiting
Lipoma
- The ORIGIN Trial (Outcome Reduction with Initial Glargine Intervention)
ClinicalTrials.gov Identifier: NCT00069784 - Active, not recruiting
Diabetes Mellitus, Non-Insulin-Dependent
- Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma
ClinicalTrials.gov Identifier: NCT00307606 - Recruiting
Breast Neoplasms; Mastectomy
- To Find the Best Dose of pVGI.1(VEGF2) to Benefit Angina Patients when given with an Experimental Injection Catheter
ClinicalTrials.gov Identifier: NCT00090714 - Active, not recruiting
Angina Pectoris
- Safety and Effectiveness of SeeMore (EVP 1001-1 Injection) for MRI in Heart Patients
ClinicalTrials.gov Identifier: NCT00340925 - Recruiting
Myocardial Infarction
- Sentinel Lymph Node Biopsy Using Peritumoral Injection With Blue Dye Confirmation
ClinicalTrials.gov Identifier: NCT00575744 - Recruiting
Breast Cancer
- An Observational Study Evaluating SYMLIN® (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes
ClinicalTrials.gov Identifier: NCT00229658 - Active, not recruiting
Type 1 Diabetes Mellitus; Type 2 Diabetes Mellitus
- A Study to Evaluate Nutropin AQ for the Treatment of Growth Restriction in Children with Cystic Fibrosis
ClinicalTrials.gov Identifier: NCT00079742 - Active, not recruiting
Cystic Fibrosis
- Injection Methods in Finding the Sentinel Lymph Node During Lymphatic Mapping and Sentinel Lymph Node Biopsy in Patients With Invasive Breast Cancer
ClinicalTrials.gov Identifier: NCT00438477 - Active, not recruiting
Breast Cancer
- Comparison Study of Operation and Percutaneous Ethanol Injection Therapy for Small, Solitary HCC
ClinicalTrials.gov Identifier: NCT00357422 - Recruiting
Hepatocellular Carcinoma
- Comparison Study of Transarterial Chemoembolization and Percutaneous Ethanol Injection for Multiple, Small HCCs
ClinicalTrials.gov Identifier: NCT00357474 - Recruiting
Hepatocellular Carcinoma
- Safety Study of IHL-305 (Irinotecan Liposome Injection) to Treat Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00364143 - Recruiting
Cancer
- The Impact of an Epidural Ropivacaine-Neostigmine Injection for Perineal Analgesia at the End of Labor.
ClinicalTrials.gov Identifier: NCT00407290 - Recruiting
Pregnancy; Vaginal Delivery
- Sub-Tenon’s Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System for Cataract Surgery
ClinicalTrials.gov Identifier: NCT00431028 - Recruiting
Inflammation; Bacterial Infections
- This is a Prospective, Randomized, Double-Blind Study Comparing Intravesical Injection of Botox® to Placebo.
ClinicalTrials.gov Identifier: NCT00479596 - Recruiting
Overactive Bladder
- Phase I/II Dose Escalation Study of VELCADE® and Docetaxel in Patients with Advanced Androgen-Independent Prostate Cancer
ClinicalTrials.gov Identifier: NCT00064610 - Active, not recruiting
Prostatic Neoplasms
- Safety and Efficacy Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients with ALS
ClinicalTrials.gov Identifier: NCT00125203 - Active, not recruiting
Amyotrophic Lateral Sclerosis; Sialorrhea
- Intramyocardial Injection of Autologous Aldehyde Dehydrogenase-Bright Stem Cells for Therapeutic Angiogenesis
ClinicalTrials.gov Identifier: NCT00314366 - Recruiting
Coronary Artery Disease
- Corticosteroid Injection for Common Upper Extremity Problems
ClinicalTrials.gov Identifier: NCT00438672 - Recruiting
Lateral Elbow Pain; deQuervain’s Tendonitis; CMC Arthritis
- Injection of ex Vivo Amplified G-CSF Mobilised Autologous Peripheral Blood Stem Cell Transplantation
ClinicalTrials.gov Identifier: NCT00461955 - Recruiting
Multiple Myeloma
- A Phase 1 Safety Study of Single and Repeated Doses of JSM6427 (Intravitreal Injection) to Treat AMD
ClinicalTrials.gov Identifier: NCT00536016 - Recruiting
Macular Degeneration
- Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis
ClinicalTrials.gov Identifier: NCT00144820 - Active, not recruiting
Osteoarthritis, Knee
- Phase 2b Study of VELCADE Alone and VELCADE plus Irinotecan in Patients with Relapsed or Refractory Colorectal Carcinoma
ClinicalTrials.gov Identifier: NCT00051987 - Active, not recruiting
Colorectal Carcinoma
- Safety Study of MBP-426 (Liposomal Oxaliplatin Suspension for Injection) to Treat Advanced or Metastatic Solid Tumors
ClinicalTrials.gov Identifier: NCT00355888 - Recruiting
Cancer
- Feasibility Study of the Effect of Intra-Dermal Insulin Injection on Blood Glucose Levels After Eating
ClinicalTrials.gov Identifier: NCT00553488 - Recruiting
Diabetes Mellitus, Type 1
- Factors Predicting Efficacy of Allergen Injection Immunotherapy for Grass Pollen Hayfever: a Pilot Study.
ClinicalTrials.gov Identifier: NCT00135629 - Active, not recruiting
Seasonal Allergic Rhinoconjunctivitis
- Valganciclovir in Patients with CMV Retinitis and AIDS Who Cannot Take Drugs by Injection
ClinicalTrials.gov Identifier: NCT00017784 - Active, not recruiting
Cytomegalovirus Retinitis; HIV Infections
- Vincristine, DOXIL® (Doxorubicin HCl Liposome Injection) and Dexamethasone vs. Vincristine, Doxorubicin, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00344422 - Active, not recruiting
M-Protein; Multiple Myeloma; Myeloma; Myeloma Proteins
- Depo-Provera: Evaluation of BMDensity and Total Body Ca Adolescent DP150CI Users and Non-Hormonal Contraception
ClinicalTrials.gov Identifier: NCT00139685 - Active, not recruiting
Contraception; Bone Density
- Evaluation of the Effects of L-Carnitine Injection in Patients Undergoing Hemodialysis
ClinicalTrials.gov Identifier: NCT00173706 - Recruiting
Cardiac Complications; Signs and Symptoms; Muscle Weakness; Anemia; Hypotension
- Thal/Dex (Thalidomide and Dexamethasone) vs. Dd-T (Doxil, Dexamethasone and Thalidomide) in Multiple Myeloma Patients
ClinicalTrials.gov Identifier: NCT00097981 - Active, not recruiting
Multiple Myeloma
- Treatment of Chronic Lymphocytic B-Leukemia with IL-2 and CD-40 Autologous Tumor Cells
ClinicalTrials.gov Identifier: NCT00058786 - Active, not recruiting
Chronic Lymphocytic B-Leukemia
- EUS-Guided Pancreatic Injection of Cyst (EPIC) Trial
ClinicalTrials.gov Identifier: NCT00233038 - Recruiting
Pancreatic Cystadenoma.
- Pore Excision, Curettage, and Injection of Cymetra for Pilonidal Disease
ClinicalTrials.gov Identifier: NCT00493493 - Recruiting
Pilonidal Sinus
- One Time Injection of Bacteria to Treat Solid Tumors That Have Not Responded to Standard Therapy
ClinicalTrials.gov Identifier: NCT00358397 - Recruiting
Tumors
- Programmed Intermittent Epidural Bolus Time Interval and Injection Volume
ClinicalTrials.gov Identifier: NCT00417027 - Recruiting
Analgesia, Epidural
- Does Intravitreal Injection of Triamcinolone Acetonide Impairs the Adrenal Function
ClinicalTrials.gov Identifier: NCT00561236 - Recruiting
Secondary Adrenal Insuffisency
- Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer
ClinicalTrials.gov Identifier: NCT00016276 - Completed
cardiac toxicity; stage IIIB breast cancer; stage IIIA breast cancer; inflammatory breast cancer; stage IV breast cancer
- Efficacy and Safety of Hematide™ Injection in the Treatment of Anemia in Patients With Chronic Kidney Disease
ClinicalTrials.gov Identifier: NCT00314795 - Recruiting
Anemia
- Lunch Time Insulin Injection by School Nurse for Poorly Controlled Diabetes
ClinicalTrials.gov Identifier: NCT00340613 - Recruiting
Type 1 Diabetes
- Ultrasound Guided Sandostatin LAR Injection in Acromegaly
ClinicalTrials.gov Identifier: NCT00552071 - Recruiting
Acromegaly
- Cardiovascular Safety Study of Magnevist® Injection at Two Dose Levels and Two Injection Rates in Normal Subjects
ClinicalTrials.gov Identifier: NCT00310596 - Completed
Healthy
- A Phase 4 Pharmacokinetic Study of Hectorol Injection and Zemplar Injection in CKD Subjects on Hemodialysis
ClinicalTrials.gov Identifier: NCT00454350 - Completed
Secondary Hyperparathyroidism
- Open-Label Phase 1/2 Study of VELCADE (Bortezomib) for Injection in Patients With Light-Chain (AL)-Amyloidosis
ClinicalTrials.gov Identifier: NCT00298766 - Recruiting
Amyloidosis
- Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Joint
ClinicalTrials.gov Identifier: NCT00403273 - Recruiting
Arthroplasty, Replacement, Knee
- Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug Users
ClinicalTrials.gov Identifier: NCT00194480 - Recruiting
Substance-Related Disorders; Hepatitis
Resources
- Dexrazoxane Injection (Drug Digest)
- Zinecard (Drug Digest)

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