Not Signed In -
Dronabinol |
Marinol |
Clinical Trial: Comparing the Effects of Smoked and Oral Marijuana in Individuals with HIV/AIDS
This study is currently recruiting patients.
|
Purpose
Smoked marijuana (MJ) and dronabinol (also known as THC or by the trade name Marinol) are used to increase appetite, food intake, and weight in patients with HIV who experience unintended weight loss. This study will compare the effects of MJ and Marinol use in marijuana smokers who are HIV infected.
| Condition | Treatment or Intervention | Phase |
|---|---|---|
| HIV Infections | Drug: dronabinol | Phase I Phase II |
MedlinePlus related topics: AIDS
Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Efficacy Study
Official Title: THC and Marijuana--Effects in Individuals with HIV/AIDS
Expected Total Enrollment: 30
Study start: December 2001
Little is known about the efficacy and tolerability of oral THC versus smoked MJ in a clinically relevant population. Additionally, it is not clear how THC's effects vary as a function of the duration of treatment or the patient’s current patterns of smoked MJ use. This study directly compares 3 doses of smoked marijuana and 3 doses of Marinol across a range of behavioral measures in HIV infected marijuana smokers.
Outcome measures will include analysis of food intake, body composition, mood, physical symptoms (e.g., nausea, stomach pain), psychomotor task performance, and sleep.
Eligibility
Ages Eligible for Study: 21 Years - 50 Years, Genders Eligible for Study: Both
Criteria
Location and Contact Information
New York
New York State Psychiatric Institute, New York, New York, 10032, United States; Recruiting
Margaret Haney, PhD, Principal Investigator, New York State Psychiatric Institute
More Information
Record last reviewed: November 2004
Last Updated: November 18, 2004
Record first received: March 9, 2004
ClinicalTrials.gov Identifier: NCT00079560
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- Dronabinol (Drug Digest)
- Marinol (Drug Digest)
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