Drotrecogin alfa |
Xigris |
Image:Drotrecogin alfa.png Drotrecogin alfa Systematic (IUPAC) name Activated human protein C Identifiers CAS number 60202-16-6 ATC code B01AD10 PubChem ? DrugBank BTD00068 Chemical data Formula C1786H2779N509O519S29 Mol. weight 55000 g/mol Pharmacokinetic data Bioavailability 100 % (i.v. application only) Metabolism through endogenous plasma protease inhibitors Half life less than 2 hours Excretion ? Therapeutic considerations Pregnancy ca ...
Wikipedia - [full article]
Resources
- Drotrecogin alfa (Drug Digest)
- Xigris (Drug Digest)
Drotrecogin alfa News Headlines
- Lilly Plans New Clinical Trial Of Xigris(R)
MedicalNewsToday - Tue, 27 Feb 2007 08:00 EST
- Human Genome Sciences Initiates Phase 3 Clinical Trial Of Albuferon(R) With Ribavirin In Patients With Chronic Hepatitis C Genotypes 2 And 3
MedicalNewsToday - Wed, 28 Feb 2007 08:00 EST
- Dainippon Sumitomo Pharma Announces Launch Of "Replagal(R) 3.5 Mg" For Anderson-Fabry Disease
MedicalNewsToday - Sun, 18 Feb 2007 08:00 EST
- Biolex Therapeutics Announces Initiation Of Locteron(TM) Phase 2 Clinical Study In Chronic Hepatitis C
MedicalNewsToday - Wed, 31 Jan 2007 08:00 EST
- Copegus Approved In Japan As Combination Therapy With Pegasys For Patients With Chronic Hepatitis C
MedicalNewsToday - Mon, 29 Jan 2007 08:00 EST
- Amgen Responds To Reports About Use And Safety Of EPOGEN And Aranesp In CKD Anemia Therapy
MedicalNewsToday - Mon, 11 Dec 2006 08:00 EST
- Majority Of Cancer-Related Anemia Patients Treated With PROCRIT(R) (Epoetin Alfa) Once Every Three Weeks Achieved Target Hemoglobin
MedicalNewsToday - Sat, 09 Dec 2006 08:00 EST
- Assisted Living Compensation Report Released - First Ever Details On Salaries, From Front-line To Corner Office
MedicalNewsToday - Fri, 01 Dec 2006 08:00 EST
- New Phase 2 Data Show Promise Of Aranesp(R) Treatment For Anemia Of Cancer
MedicalNewsToday - Mon, 11 Dec 2006 08:00 EST
- Majority Of Anemic Chronic Kidney Disease Pre-Dialysis Patients Achieved Target Hemoglobin Range With PROCRIT® (Epoetin Alfa)
MedicalNewsToday - Thu, 23 Nov 2006 08:00 EST
- Final Phase 2 Data Continue To Show Promising Results After One Year Of Aranesp(R) Treatment For Anemia In Patients With Myelodysplastic Syndromes
MedicalNewsToday - Mon, 11 Dec 2006 08:00 EST
- Majority Of Anemic Chronic Kidney Disease Pre-Dialysis Patients Achieved Target Hemoglobin Range With PROCRIT(R) (Epoetin Alfa) Therapy
MedicalNewsToday - Mon, 20 Nov 2006 08:00 EST
- District Court Judge Denies Preliminary Injunction In Ortho V. Amgen Suit
MedicalNewsToday - Thu, 23 Nov 2006 08:00 EST
- Amgen Receives Complete Response Letter For Extended Dosing Of Aranesp(R) For Patients With Chronic Kidney Disease And Anemia
MedicalNewsToday - Sun, 15 Oct 2006 07:00 EST
- Study Shows Patient Preference For Gonal-f(R) RFF Pen To Treat Infertility
MedicalNewsToday - Tue, 26 Sep 2006 07:00 EST
- Amgen Launches Aranesp Prefilled Sureclick™ Autoinjector For Treatment Of Anemia
MedicalNewsToday - Sun, 10 Sep 2006 11:00 EST
- New Autoinjector Offers Secure And Simple Way To Administer Anemia Treatment Associated With Chemotherapy And Chronic Kidney Disease
MedicalNewsToday - Sun, 10 Sep 2006 07:00 EST
- Advate's Safety Profile Confirmed For Haemophilia Therapy
MedicalNewsToday - Mon, 21 Aug 2006 07:00 EST
- African Americans Have Lower Response Rate To Standard Therapy For Hepatitis C
MedicalNewsToday - Sat, 19 Aug 2006 10:00 EST
- Aranesp May Lower Hospitalization Risk And All-Cause Mortality In Heart Failure Patients With Anemia, Based On A Prespecified Pooled Analysis
MedicalNewsToday - Mon, 26 Jun 2006 06:00 EST
- Study Explores Use Of PROCRIT(R) (Epoetin Alfa) Once Every Two Weeks As Initiation Treatment For Chemotherapy-Related Anemia
MedicalNewsToday - Sun, 04 Jun 2006 06:00 EST
- Study Of Aranesp(R) Dosed Every Two Weeks Versus Epoetin Alfa Dosed Weekly
MedicalNewsToday - Mon, 22 May 2006 06:00 EST
- ASCO 2006 - Plenary Session: Renal Cell Cancer
MedicalNewsToday - Sun, 11 Jun 2006 11:00 EST
- European Medicines Agency Adopts First Positive Opinion For A Medicinal Product Derived From Transgenic Biotechnology
MedicalNewsToday - Mon, 05 Jun 2006 02:00 EST
- Hepatitis C Patients Benefit From Combination Of VX-950 And Pegylated Interferon
MedicalNewsToday - Tue, 02 May 2006 06:00 EST
- FDA Approves First Treatment For Pompe Disease
MedicalNewsToday - Mon, 01 May 2006 06:00 EST
- Pompe Disease Drug Myozyme Gets FDA Approval
MedicalNewsToday - Sat, 29 Apr 2006 12:00 EST
- Update On Oral HCV Protease Inhibitor SCH 503034 Clinical Development Program For Hepatitis C
MedicalNewsToday - Wed, 26 Apr 2006 06:00 EST
- Kaiser Daily Health Policy Report Highlights Recent Developments In Medicare
MedicalNewsToday - Thu, 06 Apr 2006 07:00 EST
- FDA Approves Extended Dosing Of Aranesp
MedicalNewsToday - Thu, 30 Mar 2006 08:00 EST
- Amgen''s Phase 3 RED-HF(TM) Trial Will Evaluate The Clinical Effect Of Treating Anemia In Patients With Symptomatic Heart Failure
MedicalNewsToday - Sun, 19 Mar 2006 11:00 EST
- Gilead Sciences Welcomes Guidance From Nice On Treatment Of Chronic Hepatitis B
MedicalNewsToday - Thu, 23 Feb 2006 12:00 EST
- People With Chronic Hepatitis B To Benefit From Guidance On New Drugs And Treatments, UK
MedicalNewsToday - Wed, 22 Feb 2006 01:00 EST
- Some Highlights From The February 15 JNCI
MedicalNewsToday - Sun, 19 Feb 2006 02:00 EST
- Some Highlights From The February 15 JNCI
MedicalNewsToday - Sun, 19 Feb 2006 02:00 EST
- Schering-Plough Initiates PEG-INTRON(R) Maintenance Study In Patients Coinfected With Hepatitis C And HIV
MedicalNewsToday - Sun, 15 Jan 2006 11:00 EST
- Chronic Hepatitis C Treatment, Peg-Intron(R) And Rebetol(R) Approved In Japan
MedicalNewsToday - Tue, 27 Dec 2005 11:00 EST
- Head-To-Head Study Of Treatments For Chemotherapy-Related Anemia Published In The Oncologist
MedicalNewsToday - Fri, 23 Sep 2005 06:00 EST
- Phase 3 Trial Starts to Evaluate the Impact of Treating Anemia with Darbepoetin Alfa in Patients with Heart Failure
MedicalNewsToday - Tue, 06 Sep 2005 12:00 EST
- Procrit® (Epoetin Alfa) Maintenance Treatment For Patients With Anemia From Chronic Kidney Disease
MedicalNewsToday - Mon, 15 Aug 2005 09:00 EST
- Major Response with Aranesp(R) in Anemic Patients with Myelodysplastic Syndromes (MDS)
MedicalNewsToday - Sun, 10 Jul 2005 06:00 EST
- Major response with Aranesp(R) in anemic patients with MDS
MedicalNewsToday - Thu, 07 Jul 2005 04:00 EST
- NeoRecormon offers patients maximum anaemia control with minimum injection discomfort compared to Aranesp
MedicalNewsToday - Fri, 03 Jun 2005 05:00 EST
- Treating children with chronic hepatitis C - PegInterferon-alfa-2b with ribavirin shows promise
MedicalNewsToday - Mon, 02 May 2005 06:00 EST
- Chemotherapy-Induced Anemia - Amgen Submits Supplemental Biologics License Application for Aranesp Extended Dosing
MedicalNewsToday - Mon, 09 May 2005 04:00 EST

Not Signed In -


