Hydroxyurea Clinical Trials

• Hydroxyurea in Treating Patients With Unresectable Benign Meningioma
  ClinicalTrials.gov Identifier: NCT00003590 - Active, not recruiting
  recurrent adult brain tumor; grade I meningioma
  
• A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy
  ClinicalTrials.gov Identifier: NCT00083746 - Active, not recruiting
  Spinal Muscular Atrophy
  
• Hydroxyurea Plus Combination Chemotherapy in Patients With Non-small Cell Lung Cancer
  ClinicalTrials.gov Identifier: NCT00002887 - Active, not recruiting
  recurrent non-small cell lung cancer
  
• Hydroxyurea for the Treatment of Patients with Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00001197 - Active, not recruiting
  Sickle Cell Anemia
  
• Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH)
  ClinicalTrials.gov Identifier: NCT00000586 - Active, not recruiting
  Anemia, Sickle Cell; Hematologic Diseases; Hemoglobinopathies
  
• Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00143572 - Active, not recruiting
  Anemia, Sickle Cell
  
• A Pilot Therapeutic Trial Using Hydroxyurea in Type II and III Spinal Muscular Atrophy Patients
  ClinicalTrials.gov Identifier: NCT00084006 - Active, not recruiting
  Spinal Muscular Atrophy
  
• Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00056433 - Active, not recruiting
  Sickle Cell Anemia
  
• Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00023959 - Active, not recruiting
  Head and Neck Cancer
  
• Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes
  ClinicalTrials.gov Identifier: NCT00004404 - Recruiting
  Sickle Cell Anemia
  
• Pediatric Hydroxyurea in Sickle Cell Anemia (BABY HUG)
  ClinicalTrials.gov Identifier: NCT00006400 - Recruiting
  Blood Disease; Anemia, Sickle Cell
  
• Stroke with Transfusions Changing to Hydroxyurea (SWITCH)
  ClinicalTrials.gov Identifier: NCT00122980 - Recruiting
  Hemochromatosis; Cerebrovascular Accident; Anemia, Sickle Cell; Blood Disease
  
• Hydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma
  ClinicalTrials.gov Identifier: NCT00006119 - Active, not recruiting
  recurrent adult brain tumor; grade III meningioma; grade I meningioma; grade II meningioma
  
• Homoharringtonine Compared With Hydroxyurea for Chronic Myelogenous Leukemia That Has Not Responded to Interferon alfa
  ClinicalTrials.gov Identifier: NCT00004933 - Active, not recruiting
  Philadelphia chromosome positive chronic myelogenous leukemia; chronic phase chronic myelogenous leukemia; refractory chronic myelogenous leukemia
  
• Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00004492 - Recruiting
  Sickle Cell Anemia
  
• Phase III Study of Imatinib Mesylate in Combination with Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients with Temozolomide Resistant Progressive Glioblastoma
  ClinicalTrials.gov Identifier: NCT00154375 - Completed
  Glioblastoma multiforme, astrocytoma
  
• Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma
  ClinicalTrials.gov Identifier: NCT00354913 - Recruiting
  Brain and Central Nervous System Tumors
  
• A Pilot Theraputic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients
  ClinicalTrials.gov Identifier: NCT00568698 - Active, not recruiting
  Muscular Atrophy, Spinal
  
• Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma
  ClinicalTrials.gov Identifier: NCT00387933 - Recruiting
  Brain and Central Nervous System Tumors
  
• The Safety and Effectiveness of Hydroxyurea and ddI Used Individually or Together in HIV-Infected Patients
  ClinicalTrials.gov Identifier: NCT00001074 - Completed
  HIV Infections
  
• Efficacy and Safety of Imatinib Mesylate Plus Hydroxyurea (HU) in Patients With Recurrent Glioblastoma Multiforme (GBM)
  ClinicalTrials.gov Identifier: NCT00290771 - Active, not recruiting
  Recurrent Glioblastoma Multiforme (GBM)
  
• Efficacy and Safety of Imatinib Mesylate Plus Hydroxyurea (HU) in Patients With Recurrent Glioblastoma Multiforme (GBM)
  ClinicalTrials.gov Identifier: NCT00292149 - Active, not recruiting
  Recurrent Glioblastoma Multiforme (GBM)
  
• A Pilot Theraputic Trial Using Hydroxyurea in Type II and Type III Spinal Muscular Atrophy Patients
  ClinicalTrials.gov Identifier: NCT00568802 - Active, not recruiting
  Muscular Atrophy, Spinal
  
• Evaluating the Safety and Effectiveness of Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease (CHAMPS)
  ClinicalTrials.gov Identifier: NCT00532883 - Recruiting
  Hemoglobin SC Disease
  
• PHASE III TRIAL COMPARING, NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY VERSUS THE SAME NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY ASSOCIATED WITH DAILY HYDROXYUREA IN THE TREATMENT OF LOCALLY ADVANCED UNDIFFERENTIATED CARCIN
  ClinicalTrials.gov Identifier: NCT00180973 - Active, not recruiting
  LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE UCNT
  
• Safety and Effectiveness of Combining Hydroxyurea (HU) with Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults
  ClinicalTrials.gov Identifier: NCT00002427 - Completed
  HIV Infections
  
• A Study to Compare the Safety and Effectiveness of Anagrelide and Hydroxyurea in High-Risk Essential Thrombocythaemia Patients.
  ClinicalTrials.gov Identifier: NCT00202644 - Recruiting
  Thrombocythemia, Hemorrhagic
  
• Interferon-alfa With or Without Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
  ClinicalTrials.gov Identifier: NCT00002868 - Active, not recruiting
  chronic phase chronic myelogenous leukemia
  
• Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00270478 - Recruiting
  Sickle Cell Disease; Chronic Kidney Disease; Pulmonary Hypertension
  
• A Randomized, Double-Blind, Placebo-Controlled Trial of Hydroxyurea in Spinal Muscular Atrophy
  ClinicalTrials.gov Identifier: NCT00485511 - Recruiting
  Spinal Muscular Atrophy
  
• A Randomized, Placebo-Controlled Study of the Safety and Efficacy of Efavirenz, Didanosine, and Stavudine in Combination With or Without Hydroxyurea in Antiretroviral Naive or Experienced HIV-Infected Patients
  ClinicalTrials.gov Identifier: NCT00002230 - Completed
  HIV Infections
  
• Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00305175 - Recruiting
  Sickle Cell Disease
  
• A Pilot Open Label Trial of HIV Therapy with d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects with Early Asymptomatic HIV Infection
  ClinicalTrials.gov Identifier: NCT00002176 - Completed
  HIV Infections
  
• A Pilot Open Label Trial of HIV Therapy with d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects with Recent HIV Infection
  ClinicalTrials.gov Identifier: NCT00002177 - Completed
  HIV Infections
  
• Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer
  ClinicalTrials.gov Identifier: NCT00019474 - Active, not recruiting
  Pancreatic Cancer; Gastric Cancer; adult primary liver cancer
  
• Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)
  ClinicalTrials.gov Identifier: NCT00001958 - Completed
  Beta Thalassemia; Hemoglobinopathy
  
• A Study of TNFerade™ With Concomitant Radiotherapy, Fluorouracil, and Hydroxyurea (TNF-FHX) in Patients With Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00496535 - Recruiting
  Head and Neck Cancer; Head and Neck Neoplasms
  
• Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00002951 - Active, not recruiting
  Gastrointestinal Cancer; Neck Cancer; Oral Cancer; Throat Cancer
  
• Fluorouracil, Hydroxyurea, Cetuximab and Twice-Daily Intensity Radiation Therapy for Advanced Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00462735 - Recruiting
  Head and Neck Cancer; Cancer of the Pharynx; Cancer of the Larynx; Nose Neoplasms; Paranasal Sinus Neoplasms; Cancer of the Oral Cavity
  
• Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia
  ClinicalTrials.gov Identifier: NCT00002674 - Active, not recruiting
  accelerated phase chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia; ...
  
• Effectiveness of Early or Delayed Addition of Hydroxyurea to a Three-Drug Anti-HIV Drug Combination Including Didanosine, in Advanced HIV Patients Who Failed a First or Second Anti-HIV Triple-Drug Therapy
  ClinicalTrials.gov Identifier: NCT00008866 - Completed
  HIV Infections
  
• VNP40101M in Treating Patients With Acute Myelogenous Leukemia or High-Risk Myelodysplasia
  ClinicalTrials.gov Identifier: NCT00083187 - Active, not recruiting
  adult acute myeloid leukemia; atypical chronic myeloid leukemia; Chronic Myelomonocytic Leukemia; myelodysplastic and myeloproliferative disease; ...
  
• Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00350844 - Recruiting
  Sickle Cell Disease; Pulmonary Hypertension
  
• Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00005823 - Active, not recruiting
  Acute Myeloid Leukemia; adult acute monoblastic and acute monocytic leukemia; atypical chronic myeloid leukemia; Chronic Myelomonocytic Leukemia; ...
  
• Combination Chemotherapy Combined with Radiation Therapy in Treating Patients Who Have Stage II or Stage III Cancer of the Esophagus
  ClinicalTrials.gov Identifier: NCT00008047 - Active, not recruiting
  stage II esophageal cancer; stage III esophageal cancer
  
• Hydroxyurea in Treating Patients With Epstein-Barr Virus-Associated Primary CNS Lymphoma and AIDS
  ClinicalTrials.gov Identifier: NCT00002940 - Completed
  AIDS-related primary CNS lymphoma
  
• Interferon alfa in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
  ClinicalTrials.gov Identifier: NCT00002869 - Active, not recruiting
  Philadelphia chromosome positive chronic myelogenous leukemia; chronic phase chronic myelogenous leukemia; ...
  
• Combination Chemotherapy and Interferon alfa Followed by Surgery and/or Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer
  ClinicalTrials.gov Identifier: NCT00004897 - Active, not recruiting
  squamous cell carcinoma of the esophagus; stage III esophageal cancer; Adenocarcinoma of the Esophagus; stage I esophageal cancer; ...
  
• Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea
  ClinicalTrials.gov Identifier: NCT00480974 - Not yet recruiting
  Sickle Cell Anemia; Sickle Cell Thalassemia
  
• Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG)
  ClinicalTrials.gov Identifier: NCT00000602 - Completed
  Anemia, Sickle Cell; Hematologic Diseases; Hemoglobinopathies
  
• Chemotherapy, Interferon, and Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia
  ClinicalTrials.gov Identifier: NCT00002771 - Active, not recruiting
  chronic phase chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia; ...
  
• Safety and Effectiveness of an Anti-HIV Drug Combination With and Without Hydroxyurea in Patients With Early HIV Infection
  ClinicalTrials.gov Identifier: NCT00006339 - Terminated
  HIV Infections
  
• Chemotherapy, Biological Therapy, and/or Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia
  ClinicalTrials.gov Identifier: NCT00025402 - Active, not recruiting
  chronic phase chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia; ...
  
• Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Advanced Cancer of the Mouth, Pharynx, or Larynx
  ClinicalTrials.gov Identifier: NCT00004094 - Active, not recruiting
  stage IV squamous cell carcinoma of the lip and oral cavity; stage IV squamous cell carcinoma of the nasopharynx; ...
  
• Docetaxel Based Chemotherapy Plus Or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE)
  ClinicalTrials.gov Identifier: NCT00117572 - Recruiting
  Cancer of the Pharynx; Cancer of the Larynx; Cancer of the Nasal Cavity; Paranasal Sinus Neoplasms; Cancer of the Oral Cavity
  
• A Study of the Safety and Effectiveness of Hydroxyurea in Patients on Potent Antiretroviral Therapy and Who Have Less Than 200 Copies/ml of HIV RNA in Their Blood
  ClinicalTrials.gov Identifier: NCT00000916 - Terminated
  HIV Infections
  
• Hydroxyurea to Prevent Stroke in Children With Sickle Cell Anemia and Elevated TCD Flow Velocity
  ClinicalTrials.gov Identifier: NCT00402480 - Completed
  Stroke
  
• Imatinib Mesylate With or Without Interferon Alfa or Cytarabine Compared With Interferon Alfa Followed by Allogeneic Stem Cell Transplantation in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia
  ClinicalTrials.gov Identifier: NCT00055874 - Recruiting
  chronic phase chronic myelogenous leukemia; childhood chronic myelogenous leukemia
  
• A Study of MKC-442 in Combination with Other Anti-HIV Drugs
  ClinicalTrials.gov Identifier: NCT00002412 - Completed
  HIV Infections
  
• Safety and Effectiveness of a Combination Anti-HIV Drug Treatment
  ClinicalTrials.gov Identifier: NCT00005018 - Completed
  HIV Infections
  
• A Study to Compare the Effectiveness of Different Anti-HIV Drug Regimens in Keeping Levels of HIV in the Blood as Low as Possible
  ClinicalTrials.gov Identifier: NCT00000939 - Completed
  HIV Infections
  
• Combination Drug Treatment of Pediatric HIV Infection
  ClinicalTrials.gov Identifier: NCT00001818 - Completed
  HIV Infection
  
• Radiation Therapy in Treating Patients With Glioblastoma
  ClinicalTrials.gov Identifier: NCT00019058 - Completed
  adult glioblastoma multiforme
  
• Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer
  ClinicalTrials.gov Identifier: NCT00004089 - Completed
  anaplastic thyroid cancer
  
• Hydroxyurea in Young Children With Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00519701 - Completed
  Sickle Cell Anemia
  
• A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
  ClinicalTrials.gov Identifier: NCT00000919 - Completed
  HIV Infections
  
• Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Mouth Cancer
  ClinicalTrials.gov Identifier: NCT00004901 - Completed
  lip and oral cavity cancer; Oropharyngeal Cancer; Head and Neck Cancer
  
• Comparison of Combination Chemotherapy Regimens in Treating Patients With Advanced Stomach Cancer
  ClinicalTrials.gov Identifier: NCT00003172 - Completed
  stage III gastric cancer; recurrent gastric cancer; stage IV gastric cancer
  
• A study of the efficacy and safety of ICA-17043 (with or without hydroxyurea) in patients with sickle cell anemia.
  ClinicalTrials.gov Identifier: NCT00040677 - Completed
  Sickle Cell Disease; Sickle Cell Anemia
  
• A Study Evaluating the Long-Term Safety of ICA-17043 in Sickle Cell Disease Patients With or Without Hydroxyurea Therapy
  ClinicalTrials.gov Identifier: NCT00294541 - Terminated
  Sickle Cell Disease; Sickle Cell Anemia
  
• The Safety and Effectiveness of Didanosine Plus Stavudine Plus Nevirapine Combined with MKC-442 in HIV-Infected Patients Who Have Not Had Success with Protease Inhibitors
  ClinicalTrials.gov Identifier: NCT00002418 - Terminated
  HIV Infections
  
• The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success with Protease Inhibitors
  ClinicalTrials.gov Identifier: NCT00002420 - Terminated
  HIV Infections