Pentosan Polysulfate Sodium |
Elmiron |
Pentosan Polysulfate Pentosan polysulfate (sold under the name Elmiron) was the first --and only-- oral medication approved by the US FDA for the treatment of interstitial cystitis, also known as painful bladder syndrome. Interstitial cystitis patients struggle with symptoms of urinary frequency, urgency, pressure and/or pain, as well as nocturia (frequent urination at night), dyspareunia (painful intercourse), pain and/or discomfort while sitting in a car, while driving and/or travell ...
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Pentosan Polysulfate Sodium Clinical Trials
- An Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis.
ClinicalTrials.gov Identifier: NCT00399139 - Recruiting
Interstitial Cystitis
- An Effectiveness and Safety Study of ELMIRON® (Pentosan Polysulfate Sodium) for the Treatment of Chronic Non-Bacterial Inflammation of the Prostate Gland.
ClinicalTrials.gov Identifier: NCT00236990 - Completed
Prostatitis
- Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy
ClinicalTrials.gov Identifier: NCT00003825 - Completed
Diarrhea; Quality of Life; radiation enteritis
- A Study to Assess the Effect of Montelukast Sodium with Concomitant Administration of Inhaled Budesonide in Asthmatic Patients.
ClinicalTrials.gov Identifier: NCT00140946 - Active, not recruiting
Asthma
- Dietary Patterns, Sodium Intake and Blood Pressure (DASH - Sodium)
ClinicalTrials.gov Identifier: NCT00000608 - Active, not recruiting
Cardiovascular Diseases; Heart Diseases; Hypertension; Vascular Diseases
- Safety Study of Fondaparinux Sodium to Prevent Venous Thromboembolic Events (APOLLO)
ClinicalTrials.gov Identifier: NCT00038961 - Active, not recruiting
Venous Thrombosis
- Study of T900607-sodium in previously treated patients with ovarian cancer.
ClinicalTrials.gov Identifier: NCT00043446 - Active, not recruiting
Ovarian Neoplasms
- Extension Study of Enteric-Coated Mycophenolate Sodium With Short-Term or no Steroid Use Compared With Enteric-Coated Mycophenolate Sodium With Standard Steroid Therapy in de Novo Kidney Recipients
ClinicalTrials.gov Identifier: NCT00240955 - Active, not recruiting
Renal Transplantation
- Risedronate Sodium on Bone in Postmenopausal Women with Hormone-Receptor-Positive Early Breast Cancer
ClinicalTrials.gov Identifier: NCT00082277 - Active, not recruiting
Breast Cancer
- Study of T900607-sodium in chemotherapy naive patients with hepatocellular carcinoma.
ClinicalTrials.gov Identifier: NCT00043433 - Active, not recruiting
Hepatocellular Carcinoma
- T138067 Sodium in Treating Patients With Advanced Refractory Cancer
ClinicalTrials.gov Identifier: NCT00003359 - Active, not recruiting
Leukemia; Lymphoma; Multiple Myeloma
- Safety and Efficacy Study of the Use of Sodium Pyruvate Bronchodilation in Asthmatics
ClinicalTrials.gov Identifier: NCT00262652 - Active, not recruiting
Mild to Moderate Asthma
- Prevention of Contrast Nephropathy by Sodium Bicarbonate Versus Sodium Chloride and N-Acetylcysteine
ClinicalTrials.gov Identifier: NCT00353340 - Recruiting
Acute Renal Failure Contrast Nephropathy
- Follow-Up Study of Safety of Enteric-Coated Mycophenolate Sodium in Patients Who Successfully Completed Study CERL080A301
ClinicalTrials.gov Identifier: NCT00149929 - Active, not recruiting
Renal transplant
- Follow-Up Study of Safety of Enteric-Coated Mycophenolate Sodium in Patients Who Successfully Completed Study CERL080A0107
ClinicalTrials.gov Identifier: NCT00149916 - Active, not recruiting
Renal transplant
- Follow-Up Study of Safety of Enteric-Coated Mycophenolate Sodium in Patients Who Successfully Completed Study CERL080A302
ClinicalTrials.gov Identifier: NCT00149864 - Active, not recruiting
Renal transplant
- Study Conducted in China of the Efficacy and Safety of Enteric-Coated Mycophenolate Sodium Versus Mycophenolate Mofetil in Adult De Novo Renal Transplant Patients
ClinicalTrials.gov Identifier: NCT00149903 - Active, not recruiting
Renal transplant
- A One-Year, Open Label Study to Investigate the Safety and the Effect of Enteric-Coated Mycophenolate Sodium (EC-MPS) in Combination with Cyclosporine Microemulsion in De Novo Kidney Transplant Recipients.
ClinicalTrials.gov Identifier: NCT00154245 - Active, not recruiting
Kidney Transplantation
- Pegaptanib Sodium (Macugen) Compared to Sham Injection in Patients with Diabetic Macular Edema (DME) Involving the Center of the Macula
ClinicalTrials.gov Identifier: NCT00148811 - Active, not recruiting
Diabetic Macular Edema
- Genasense™ (Oblimersen Sodium), Fludarabine, and Rituximab in Subjects with Chronic Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00078234 - Active, not recruiting
Chronic Lymphocytic Leukemia
- Safety Study of Oral Sodium Phenylbutyrate in Subjects with ALS (Amyotrophic Lateral Sclerosis)
ClinicalTrials.gov Identifier: NCT00107770 - Active, not recruiting
Amyotrophic Lateral Sclerosis
- Phase III Randomized Study of Sodium Dichloroacetate in Children with Congenital Lactic Acidosis
ClinicalTrials.gov Identifier: NCT00004490 - Active, not recruiting
Lactic Acidosis
- Trial of Xyrem® (Sodium Oxybate) for the Treatment of Narcolepsy
ClinicalTrials.gov Identifier: NCT00132873 - Recruiting
Narcolepsy
- Dose-Response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating Room
ClinicalTrials.gov Identifier: NCT00135668 - Recruiting
Controlled Hypotension
- Conversion Trial from Mycophenolate Mofetil (MMF) to Enteric-Coated Mycophenolate Sodium (EC-MPS) in Stable Transplanted Patients Suffering from Gastrointestinal (GI) Adverse Events While on Mycophenolate Mofetil Therapy (MMF) Therapy.
ClinicalTrials.gov Identifier: NCT00149942 - Active, not recruiting
Kidney and liver transplantation
- Clinical Investigation Into the Efficacy and Tolerability of Inhaled Treprostinil Sodium in Patients with Severe PAH
ClinicalTrials.gov Identifier: NCT00147199 - Recruiting
Pulmonary Arterial Hypertension
- Efficacy, Tolerability and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) with Cyclosporine Microemulsion and Steroids in Pediatric De Novo Renal Transplant Patients
ClinicalTrials.gov Identifier: NCT00154206 - Active, not recruiting
De novo pediatric renal transplantation
- Safety and Tolerability of Enteric-Coated Mycohenolate Sodium (EC-MPS) in Renal Transplant Patients with GI Intolerance
ClinicalTrials.gov Identifier: NCT00150020 - Recruiting
Renal Transplantation
- Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic Acidemia
ClinicalTrials.gov Identifier: NCT00004493 - Recruiting
Lactic Acidosis
- Effects of Divalproex Sodium on Food Intake, Energy Expenditure, and Posture Allocation
ClinicalTrials.gov Identifier: NCT00287053 - Active, not recruiting
Healthy
- A Study of Sitaxsentan Sodium in Subjects With Diastolic Heart Failure
ClinicalTrials.gov Identifier: NCT00303498 - Active, not recruiting
Ventricular Dysfunction, Left
- Sodium Stibogluconate and Interferon in Treating Patients With Advanced Solid Tumors, Lymphoma, or Myeloma
ClinicalTrials.gov Identifier: NCT00311558 - Active, not recruiting
Cancer
- Extension Study on the Safety and Efficacy of Enteric-Coated Mycophenolate Sodium in Kidney Transplant Recipients
ClinicalTrials.gov Identifier: NCT00239070 - Active, not recruiting
Renal Transplantation
- Extension Study of the Safety and Efficacy of Enteric-Coated Mycophenolate Sodium in Kidney Transplant Recipients
ClinicalTrials.gov Identifier: NCT00241059 - Active, not recruiting
Renal Transplantation
- Hemodynamic Effects of Aliskiren Compared to Captopril on the Kidney in Healthy Volunteers on a Low- and High- Sodium Diet
ClinicalTrials.gov Identifier: NCT00518765 - Active, not recruiting
Hypertension
- Sodium Salicylate in Treating Patients With Advanced Myelodysplastic Syndrome, Acute Myelogenous Leukemia, or Chronic Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00004245 - Active, not recruiting
adult acute myeloid leukemia; atypical chronic myeloid leukemia; childhood acute myeloid leukemia and other myeloid malignancies; ...
- Effect of Nitrite on Exercise Physiology and Metabolism
ClinicalTrials.gov Identifier: NCT00105222 - Active, not recruiting
- Nitrite Infusion Studies
ClinicalTrials.gov Identifier: NCT00102271 - Active, not recruiting
- Safety and Efficacy of Enteric-Coated Mycophenolate Sodium (EC-MPS) Plus Valsartan in Patients With Kidney Transplants (MYTHOS
ClinicalTrials.gov Identifier: NCT00308425 - Active, not recruiting
De Novo Renal Transplantation
- Phase II Randomized Study of Alendronate Sodium for Osteopenia in Patients with Gaucher's Disease
ClinicalTrials.gov Identifier: NCT00004488 - Recruiting
Gaucher's Disease; Osteopenia
- Efficacy and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) in Kidney Transplant Recipients
ClinicalTrials.gov Identifier: NCT00229138 - Active, not recruiting
Kidney Transplantation
- A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
ClinicalTrials.gov Identifier: NCT00330460 - Active, not recruiting
Osteoporosis; Osteopenia
- Photodynamic Therapy Using Porfimer Sodium in Treating Patients Who Are Undergoing Surgery for Recurrent Malignant Astrocytoma
ClinicalTrials.gov Identifier: NCT00118222 - Active, not recruiting
Mixed Gliomas; adult anaplastic astrocytoma; recurrent adult brain tumor; adult giant cell glioblastoma; adult gliosarcoma
- Dialysate Sodium Individualization in Hemodialysis
ClinicalTrials.gov Identifier: NCT00259714 - Recruiting
Hypertension in Hemodialysis Patients
- Double-Blind, Placebo-Controlled Divalproex Sodium ER in Bipolar I or Bipolar II Depression
ClinicalTrials.gov Identifier: NCT00194116 - Active, not recruiting
Bipolar Disorder
- A Multicenter, Randomized Placebo Controlled Pilot MicroCT Study to Estimate the Effect of Treatment With Denosumab (AMG 162) and Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density
ClinicalTrials.gov Identifier: NCT00293813 - Active, not recruiting
Osteoporosis
- Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders
ClinicalTrials.gov Identifier: NCT00004767 - Completed
Amino Acid Metabolism, Inborn Errors
- Extension Study of Enteric-Coated Mycophenolate Sodium in Combination With Full Dose or Reduced Dose Cyclosporine Microemulsion in Patients With de Novo Kidney Transplants
ClinicalTrials.gov Identifier: NCT00238940 - Active, not recruiting
Renal Transplantation
- Pleurectomy/Decortication With or Without Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate
ClinicalTrials.gov Identifier: NCT00165503 - Active, not recruiting
Pleural Mesothelioma; Malignant Pleural Mesothelioma
- Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate
ClinicalTrials.gov Identifier: NCT00165516 - Active, not recruiting
Pleural Mesothelioma; Malignant Pleural Mesothelioma
- Extension Study to Assess Tolerability and Safety of Enteric-Coated Mycophenolate Sodium in Renal Transplant Recipients Who Received Mycophenolate Mofetil
ClinicalTrials.gov Identifier: NCT00238966 - Active, not recruiting
Renal Transplantation
- Study of Enteric-Coated Mycophenolate Sodium Maintenance Therapy in Patients With Renal Transplant Receiving Cyclosporine Microemulsion and Steroids,
ClinicalTrials.gov Identifier: NCT00239057 - Active, not recruiting
Maintenance Renal Transplantation
- Enteric-Coated Mycophenolate Sodium on Quality of Life in Patients With Gastrointestinal Symptoms Related to Mycophenolate Mofetil Therapy After Kidney Transplantation
ClinicalTrials.gov Identifier: NCT00239005 - Not yet recruiting
Renal Transplant
- Clinical Study to Evaluate the Tolerability, Safety and Efficacy of Enteric-Coated Mycophenolate Sodium After Equimolar Conversion From Mycophenolate Mofetil (MMF) in Patients With Renal Transplant
ClinicalTrials.gov Identifier: NCT00171379 - Active, not recruiting
Prevention of Acute Rejection After Kidney Transplantation
- Clinical Study to Evaluate the Tolerability, Safety and Efficacy of Enteric-Coated Mycophenolate Sodium, After Equimolar Conversion From Mycophenolate Mofetil (MMF), in Patients With Stable Renal Transplant Receiving Tacrolimus
ClinicalTrials.gov Identifier: NCT00171392 - Active, not recruiting
Prevention of Acute Rejection After Kidney Transplantation
- Extension Study on the Efficacy and Safety of Enteric-Coated Mycophenolate Sodium Administered in de Novo Kidney Transplant Patients
ClinicalTrials.gov Identifier: NCT00239018 - Active, not recruiting
De Novo Kidney Transplantation
- Sodium Channel Expression in Human Teeth
ClinicalTrials.gov Identifier: NCT00575263 - Recruiting
Dental Pulp Disease
- Corticosteroid Therapy of Septic Shock - Corticus
ClinicalTrials.gov Identifier: NCT00147004 - Active, not recruiting
Shock, Septic
- ATX-101 (Sodium Deoxycholate for Injection) for the Treatment of Superficial Lipomas
ClinicalTrials.gov Identifier: NCT00422188 - Recruiting
Lipoma
- Prevention of Contrast Induced Nephropathy With Sodium Bicarbonate
ClinicalTrials.gov Identifier: NCT00472563 - Recruiting
Acute Kidney Failure
- Sodium Thiosulfate Treatment of Vascular Calcification in ESRD
ClinicalTrials.gov Identifier: NCT00568399 - Recruiting
Hemodialysis; Cardiovascular Diseases
- Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00019695 - Active, not recruiting
Stage IV Prostate Cancer; Bone Metastases; Adenocarcinoma of the Prostate; Recurrent Prostate Cancer
- Boronophenylalanine-Fructose Complex (BPA-F) and/or Sodium Borocaptate (BSH) Followed By Surgery in Treating Patients With Thyroid Cancer, Head and Neck Cancer, or Liver Metastases
ClinicalTrials.gov Identifier: NCT00062348 - Recruiting
Endocrine Cancer; Gastrointestinal Cancer; Head and Neck Cancer; metastatic cancer
- Formation and Severity of Pressure Ulcers Associated With 4% Albumin Vs. 0.9% Sodium Chloride
ClinicalTrials.gov Identifier: NCT00228657 - Active, not recruiting
Pressure Ulcer, Area; Pressure Ulcer, Grade; Albumin Level; Risk Score; Length of ICU Stay
- The Efficacy Study of Sodium Hyaluronate to Treat Symptomatic Hip Osteoarthritis
ClinicalTrials.gov Identifier: NCT00330135 - Active, not recruiting
Symptomatic Hip Osteoarthritis
- Efficacy of Combination Product (Sumatriptan Succinate/Naproxen Sodium) in Eletriptan Non-Responders.
ClinicalTrials.gov Identifier: NCT00382993 - Recruiting
Migraine
- Efficacy of Combination Product (Sumatriptan Succinate/Naproxen Sodium) in Eletriptan Non-Responders.
ClinicalTrials.gov Identifier: NCT00383162 - Recruiting
Migraine
- Sodium Phenylbutyrate for Treating Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder
ClinicalTrials.gov Identifier: NCT00345605 - Active, not recruiting
Argininosuccinic Aciduria; Amino Acid Metabolism, Inborn Errors; Urea Cycle Disorders
- Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors
ClinicalTrials.gov Identifier: NCT00238173 - Active, not recruiting
Bone Marrow Suppression; Brain and Central Nervous System Tumors; Drug Toxicity; Long-Term Effects Secondary to Cancer Therapy in Children
- Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine Changes
ClinicalTrials.gov Identifier: NCT00345800 - Recruiting
Narcolepsy With Cataplexy
- Clinical Trial of Sodium Bicarbonate to Prevent Contrast-Induced Nephropathy
ClinicalTrials.gov Identifier: NCT00424320 - Recruiting
Acute Kidney Failure
- An Approved Drug to Study a New Indication for Allergic Rhinitis
ClinicalTrials.gov Identifier: NCT00127647 - Active, not recruiting
Rhinitis, Allergic, Seasonal
- Effect of High and Low Sodium Diets on Blood Pressure in Hypertensive Patients Treated With Aliskiren
ClinicalTrials.gov Identifier: NCT00441064 - Recruiting
Hypertension
- Study to Assess Effects of Age, Weight, and Body Composition on the Pharmacokinetics of IV Diclofenac Sodium
ClinicalTrials.gov Identifier: NCT00509743 - Recruiting
Healthy
- Gene Therapy for the Treatment of Brain Tumors
ClinicalTrials.gov Identifier: NCT00001328 - Active, not recruiting
Brain Neoplasm; Neoplasm Metastasis
- Safety and Efficacy of Risedronate in the Treatment of Osteogenesis Imperfecta in Children
ClinicalTrials.gov Identifier: NCT00106028 - Active, not recruiting
Osteogenesis Imperfecta
- Efficacy and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) in Renal Transplant Patients
ClinicalTrials.gov Identifier: NCT00239083 - Recruiting
Kidney Transplantation
- Study Evaluating Pantoprazole Sodium Enteric-Coated Spheroid Suspension In Infants With Presumed GERD
ClinicalTrials.gov Identifier: NCT00259012 - Recruiting
Gastroesophageal Reflux
- Effects of Sodium Intake on(PK)/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker
ClinicalTrials.gov Identifier: NCT00310778 - Recruiting
Healthy
- Low Sodium Diet and Behavioral Intervention for Reversing Arterial Stiffening in Overweight Individuals
ClinicalTrials.gov Identifier: NCT00366990 - Recruiting
Cardiovascular Diseases; Obesity
- A Prospective Study of the Effect of Topical Sodium Hyaluronate Immediately Post-PKP on Time to Reepithelialization
ClinicalTrials.gov Identifier: NCT00570648 - Recruiting
Corneal Transplantation
- Comparison of Study Drug With Alendronate on How it Effects Glucocorticoid-Induced Osteoporosis
ClinicalTrials.gov Identifier: NCT00051558 - Active, not recruiting
Osteoporosis
- Efficacy and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients
ClinicalTrials.gov Identifier: NCT00312143 - Active, not recruiting
De Novo Kidney Transplant Recipients
- Carboplatin, Cyclophosphamide, and Etoposide or Etoposide Phosphate With or Without Sodium Thiosulfate in Treating Patients With High-Grade Glioma
ClinicalTrials.gov Identifier: NCT00075387 - Recruiting
adult anaplastic astrocytoma; adult anaplastic ependymoma; adult anaplastic oligodendroglioma; adult brain tumor; adult glioblastoma; ...
- Efficacy and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients
ClinicalTrials.gov Identifier: NCT00238953 - Recruiting
Renal Transplantation
- A Study to Examine the Effectiveness and Safety of Oral Ibandronate Given Once Monthly in Postmenopausal Women with Osteopenia
ClinicalTrials.gov Identifier: NCT00129623 - Active, not recruiting
Bone Disease, Metabolic; Osteopenia
- A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients with AIDS Who Have Not Had Success with Ganciclovir
ClinicalTrials.gov Identifier: NCT00002301 - Active, not recruiting
Cytomegalovirus Retinitis; HIV Infections
- Study of the Safety and Effectiveness of Rabeprazole in Treatment of Helicobacter Pylori Infection in Adults.
ClinicalTrials.gov Identifier: NCT00216450 - Active, not recruiting
Bacterial Infections; Helicobacter Infections
- Investigation Into the Therapeutic Dosage of Fondaparinux Sodium, a Medication Used to Prevent Blood Clots in Morbidly Obese Volunteers
ClinicalTrials.gov Identifier: NCT00436787 - Recruiting
Venous Thrombosis; Pulmonary Embolism
- Risperidone and Divalproex Sodium With MRI Assessment in Pediatric Bipolar
ClinicalTrials.gov Identifier: NCT00176202 - Recruiting
Bipolar Disorder
- Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia.
ClinicalTrials.gov Identifier: NCT00423605 - Recruiting
Fibromyalgia
- A Safety and Efficacy Study of Xyrem® (Sodium Oxybate) to Treat Fibromyalgia.
ClinicalTrials.gov Identifier: NCT00423813 - Recruiting
Fibromyalgia
- Urine Chloride/Creatinine Ratio for Estimation of Urine Sodium
ClinicalTrials.gov Identifier: NCT00324883 - Recruiting
Hypertension
- SOLID-Effect of Risedronate Sodium at Distal Radius in Colle's Fracture.
ClinicalTrials.gov Identifier: NCT00460733 - Recruiting
Colles' Fracture
- Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00034307 - Active, not recruiting
Pulmonary Hypertension
- Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease
ClinicalTrials.gov Identifier: NCT00095472 - Active, not recruiting
Sickle Cell Anemia
- Vasoreactivity in Carriers of Genetic Polymorphisms
ClinicalTrials.gov Identifier: NCT00160888 - Recruiting
Healthy
- Nitrite Infusion in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00103025 - Recruiting
- Enhancing Slow Wave Sleep With Sodium Oxybate
ClinicalTrials.gov Identifier: NCT00506974 - Recruiting
Sleep
- Observational Cohort Study of Sodium, Weight and CVD
ClinicalTrials.gov Identifier: NCT00006308 - Active, not recruiting
Cardiovascular Diseases; Heart Diseases; Hypertension
Resources
- Elmiron (Drug Digest)
- Pentosan Polysulfate Sodium (Drug Digest)

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