Estamustine |
Emcyt |
Article: Estramustine
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| Estramustine | |
| Systematic (IUPAC) name | |
| (17-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17- decahydro-6H-cyclopenta[a]phenanthren-3-yl) bis (2-chloroethyl)aminomethanoate | |
| Identifiers | |
| CAS number | 2998-57-4 |
| ATC code | L01XX11 |
| PubChem | 18140 |
| DrugBank | APRD00625 |
| Chemical data | |
| Formula | C23H31NCl2O3 |
| Mol. weight | 440.403 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | 20 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. | ? |
| Legal status | |
| Routes | ? |
Estramustine (Emcyt®) is a chemotherapy agent used to treat prostate cancer. It is a combination of estrogen and mechlorethamine, a nitrogen mustard.
| Chemotherapeutic agents (L01) - Chemotherapy regimens |
|---|
| L01A - Alkylating agents: Cyclophosphamide | Chlorambucil | Melphalan | Mechlorethamine | Ifosfamide | Busulfan | ThioTEPA | Lomustine | Streptozocin | Temozolomide | Dacarbazine | Cisplatin | Carboplatin | Oxaliplatin | Procarbazine | Uramustine |
| L01B - Antimetabolites: Methotrexate | Pemetrexed | Fludarabine Cytarabine | Fluorouracil | Floxuridine | Gemcitabine | Capecitabine |
| L01C - Plant alkaloids: Vinblastine | Vincristine | Vinorelbine | Etoposide | Paclitaxel | Docetaxel |
| L01D - Cytotoxic/antitumour antibiotics: Anthracycline family (Doxorubicin | Daunorubicin | Epirubicin | Idarubicin | Mitoxantrone) | Bleomycin | Mitomycin | Hydroxyurea |
| L01X - Other, including Topoisomerase inhibitors: Topotecan | Irinotecan |
Categories: Chemotherapeutic agents | Pharmacology stubs
Resources
- Emcyt (Drug Digest)
- Estamustine (Drug Digest)

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