Recent studies have investigated the use of local anesthetics (i.e. lidocaine, mepivacaine) to lessen the pain experienced with minor gynecologic procedures such as endometrial biopsy and office hysteroscopy. Local anesthetic injected into the uterine cavity has been demonstrated effective in some studies at decreasing patient pain associated with these intrauterine procedures at an anesthetic concentration of at least 2%. Based on this evidence, we hypothesized that an intrauterine lidocaine infusion may reduce patient pain during first trimester abortions.

Condition	Intervention
Pain	Drug: Intrauterine lidocaine infusion 4%

Further Study Details: 

Primary Outcomes: VAS scores during cervical dilation and uterine aspiration
Secondary Outcomes: Patient satisfaction, symptoms, lidocaine levels
Expected Total Enrollment:  80

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Female

Accepts Healthy Volunteers

Criteria

Inclusion Criteria:

• Age > 18 years old
• Good general health
• English speaking
• Confirmation of gestational age by ultrasound
• Body weight > 100 lbs.
• Pregnancy < 11 weeks

Oregon
      Planned Parenthood of the Columbia Willamette, Portland,  Oregon,  97206,  United States

Study chairs or principal investigators

Alison B Edelman, MD, MPH,  Principal Investigator,  OHSU   

Study ID Numbers:  OHSU IRB 6876
Last Updated:  July 25, 2005
Record first received:  July 20, 2005
ClinicalTrials.gov Identifier:  NCT00121329
Health Authority: United States: Institutional Review Board
ClinicalTrials.gov processed this record on 2005-08-02