Factor VIIa, Recombinant Clinical Trials

• Evaluation of Recombinant Factor VIIa in Patients With Severe Bleeding
  ClinicalTrials.gov Identifier: NCT00184548 - Recruiting
  Trauma
  
• Effect of rFVIIa on Peri-Operative Blood Loss in Patients Undergoing Major Burn
  ClinicalTrials.gov Identifier: NCT00243243 - Recruiting
  Burns
  
• "Salvage Use" of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00214656 - Recruiting
  Myocardial Ischemia; Blood Coagulation Disorders; Coronary Artery Disease; Heart Valve Diseases
  
• Recombinant Factor VIIa (NovoSeven) on Restoring Coagulation Activation
  ClinicalTrials.gov Identifier: NCT00375323 - Completed
  Hemophilia A
  
• Evaluation of Recombinant Factor VIIa in Patients With Severe Bleeding Due to Trauma
  ClinicalTrials.gov Identifier: NCT00323570 - Completed
  Trauma
  
• Dose Response to Recombinant Factor VIIa when administered for Bleed
  ClinicalTrials.gov Identifier: NCT00104455 - Completed
  Healthy
  
• Efficacy and Safety Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Previously Untreated Hemophilia A Patients
  ClinicalTrials.gov Identifier: NCT00157157 - Active, not recruiting
  Hemophilia A
  
• Preliminary Efficacy of Recombinant Factor VIIa (NovoSeven NiaStase) in Subjects with Brain Contusions
  ClinicalTrials.gov Identifier: NCT00123591 - Completed
  Contusion
  
• Recombinant Factor VIIa in Acute Intracerebral Haemorrhage
  ClinicalTrials.gov Identifier: NCT00426803 - Completed
  Spontaneous Intracerebral Haemorrhage
  
• Prophylaxis Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A
  ClinicalTrials.gov Identifier: NCT00243386 - Recruiting
  Hemophilia A
  
• Recombinant Human Keratinocyte Growth Factor in Unrelated and Related Transplants
  ClinicalTrials.gov Identifier: NCT00056875 - Active, not recruiting
  Graft Versus Host Disease
  
• Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1
  ClinicalTrials.gov Identifier: NCT00577577 - Recruiting
  Myotonic Dystrophy Type 1
  
• Dose Ranging Study of Recombinant Human Insulin-like Growth Factor I in Children with Hyperinsulinism
  ClinicalTrials.gov Identifier: NCT00004699 - Active, not recruiting
  Hyperinsulinism
  
• Phase II Long Term, Randomized Study of Recombinant Human Insulin-like Growth Factor I in Children with Hyperinsulinism
  ClinicalTrials.gov Identifier: NCT00004700 - Active, not recruiting
  Hyperinsulinism
  
• Recombinant Human Insulin-Like Growth Factor (rhIGF-1)Treatment of Short Stature Associated with IGF-1 Deficiency
  ClinicalTrials.gov Identifier: NCT00125190 - Active, not recruiting
  Insulin-Like Growth Factor-1 Deficiency; Primary IGF-1 Deficiency; IGF-1
  
• Dose-Response Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A
  ClinicalTrials.gov Identifier: NCT00289536 - Active, not recruiting
  Hemophilia A
  
• Safety study of Recombinant Factor XIII (rFXIII) in Patients with Congenital Factor XIII Deficiency
  ClinicalTrials.gov Identifier: NCT00056589 - Completed
  Congenital Factor XIII deficiency
  
• Safety and Efficacy Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Hemophilia A Patients Undergoing Surgery
  ClinicalTrials.gov Identifier: NCT00157105 - Completed
  Hemophilia A
  
• Recombinant Human Keratinocyte Growth Factor to Reduce Oral Mucositis in Hematologic Malignancy Patients Undergoing Peripheral Blood Stem Cell Transplantation After Radiation and High-dose Chemotherapy
  ClinicalTrials.gov Identifier: NCT00041665 - Completed
  Stomatitis
  
• Recombinant Human Factor IX (rFIX; BeneFIX®) in Previously Treated Patients (PTPs) with Hemophilia B
  ClinicalTrials.gov Identifier: NCT00093171 - Active, not recruiting
  Hemophilia B
  
• Study of Pharmacokinetics, Efficacy, and Safety of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients with Hemophilia A
  ClinicalTrials.gov Identifier: NCT00157040 - Completed
  Hemophilia A
  
• Lenalidomide and Recombinant Human Stem Cell Factor for Treatment of Myelodysplasia
  ClinicalTrials.gov Identifier: NCT00434239 - Recruiting
  Myelodysplasia
  
• A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers
  ClinicalTrials.gov Identifier: NCT00351767 - Active, not recruiting
  Diabetic Foot Ulcers
  
• Sequential Vaccinations in Prostate Cancer Patients
  ClinicalTrials.gov Identifier: NCT00060528 - Active, not recruiting
  Prostatic Neoplasms
  
• Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure
  ClinicalTrials.gov Identifier: NCT00225901 - Recruiting
  Liver Failure, Acute
  
• Study of Pharmacokinetics, Efficacy and Safety of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Hemophilia A Patients - A Continuation of Clinical Study 069901
  ClinicalTrials.gov Identifier: NCT00157053 - Completed
  Hemophilia A
  
• Biological Therapy in Treating Patients Undergoing Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation for Hematologic Cancer
  ClinicalTrials.gov Identifier: NCT00004061 - Active, not recruiting
  Leukemia; Lymphoma
  
• Study to Evaluate the Safety, Tolerability and Immunogenicity of Recombinant Botulinum Vaccine A/B in Healthy Adults
  ClinicalTrials.gov Identifier: NCT00098098 - Recruiting
  Recombinant Botulinum Vaccine a/B
  
• Study of Recombinant Human Insulin-Like Growth Factor I in Patients with Severe Insulin Resistance
  ClinicalTrials.gov Identifier: NCT00004419 - Recruiting
  Insulin Resistance; Hyperglycemia
  
• A Study to Evaluate the Efficacy and Safety of Palifermin (Recombinant Human Keratinocyte Growth Factor, rHuKGF) for the Reduction of Oral Mucositis in Subjects with Advanced Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00131638 - Active, not recruiting
  Head and Neck Cancer
  
• Short Term Study of Recombinant Human Insulin-like Growth Factor I in Children with Hyperinsulinism
  ClinicalTrials.gov Identifier: NCT00004825 - Completed
  Hyperinsulinism
  
• Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Unilateral Knee Replacement
  ClinicalTrials.gov Identifier: NCT00357656 - Recruiting
  Hemophilia A
  
• Vaccine Therapy and GM-CSF in Treating Patients With Prostate Cancer That Progressed After Surgery and/or Radiation Therapy
  ClinicalTrials.gov Identifier: NCT00108732 - Active, not recruiting
  recurrent prostate cancer; stage I prostate cancer; stage II prostate cancer; stage III prostate cancer
  
• Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) with Advate (FLrFVIII) in Hemophilia A
  ClinicalTrials.gov Identifier: NCT00141843 - Active, not recruiting
  Hemophilia A
  
• Study Evaluating B-Domain Deleted Recombinant Factor VIII (BDDrFVIII, ReFacto AF) in Patients With Hemophilia A Undergoing Elective Major Surgery
  ClinicalTrials.gov Identifier: NCT00243659 - Recruiting
  Hemophilia A
  
• Active Specific Intranodal Immunotherapy of Recombinant Vaccinia Virus in Locally Advanced to Metastatic Melanoma
  ClinicalTrials.gov Identifier: NCT00116597 - Active, not recruiting
  Melanoma
  
• Continuously Infused Intracerebral (IC) Recombinant-Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (r-metHuGDNF) for the Treatment of Idiopathic Parkinson's Disease
  ClinicalTrials.gov Identifier: NCT00006488 - Completed
  Parkinson Disease
  
• A Phase I Feasibility Study of an Intraprostatic PSA-Based Vaccine in Prostate Cancer Patients with Local Failure Following Radiotherapy
  ClinicalTrials.gov Identifier: NCT00096551 - Recruiting
  Prostatic Neoplasms
  
• Diet/Growth Factor Mechanisms of Gut Adaptation
  ClinicalTrials.gov Identifier: NCT00067860 - Recruiting
  Short Bowel Syndrome
  
• Factor VIIa in Acute Intracerebral Haemorrhage
  ClinicalTrials.gov Identifier: NCT00266006 - Completed
  Intracerebral Haemorrhage
  
• A Randomized, Open-Label, Phase II, International Study of Subcutaneous Recombinant Interleukin-2 (Proleukin) With and Without Concomitant Antiretroviral Therapy in Patients with HIV-1 Infection and CD4+ Cell Counts Greater Than or Equal to 300/mm(3)
  ClinicalTrials.gov Identifier: NCT00106730 - Recruiting
  
  
• Safety/Efficacy Study of Oral Recombinant Human Lactoferrin in Renal Cell Carcinoma
  ClinicalTrials.gov Identifier: NCT00095186 - Active, not recruiting
  Carcinoma, Renal Cell
  
• Safety and Immunogenicity of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small Cell Lung Cancer
  ClinicalTrials.gov Identifier: NCT00062907 - Recruiting
  Non-small cell lung cancer
  
• An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or
  ClinicalTrials.gov Identifier: NCT00002255 - Completed
  HIV Infections
  
• Vaccine Therapy in Treating Patients With Metastatic Melanoma
  ClinicalTrials.gov Identifier: NCT00002817 - Active, not recruiting
  stage III melanoma; Stage IV Melanoma; Recurrent Melanoma
  
• A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory Neuropathy
  ClinicalTrials.gov Identifier: NCT00000842 - Completed
  HIV Infections; Peripheral Nervous System Disease
  
• Vaccine Therapy With or Without Sargramostim in Treating Patients With Cancer
  ClinicalTrials.gov Identifier: NCT00009958 - Active, not recruiting
  unspecified adult solid tumor, protocol specific
  
• Vaccine Therapy in Treating Patients With Metastatic Breast Cancer
  ClinicalTrials.gov Identifier: NCT00003761 - Active, not recruiting
  stage IV breast cancer; recurrent breast cancer
  
• Docetaxel With or Without Vaccine Therapy and GM-CSF in Treating Patients With Metastatic Breast Cancer
  ClinicalTrials.gov Identifier: NCT00217750 - Recruiting
  Male Breast Cancer; recurrent breast cancer; stage IV breast cancer
  
• A Phase I Trial of Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (rHuGM-CSF), Recombinant Alpha Interferon and Azidothymidine (AZT) in AIDS-Associated Kaposi's Sarcoma
  ClinicalTrials.gov Identifier: NCT00000694 - Completed
  Sarcoma, Kaposi; HIV Infections
  
• Use of NovoSeven® in Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00154427 - Recruiting
  Post-operative bleeding following cardiac surgery
  
• Comparison Between Recombinant Versus Urinary hCG for Ovulation Induction
  ClinicalTrials.gov Identifier: NCT00415766 - Active, not recruiting
  Infertility
  
• Study of the Efficacy of Human Recombinant Factor VIII (Kogenate FS) Reconstituted in Pegylated Liposomes.
  ClinicalTrials.gov Identifier: NCT00245297 - Completed
  Haemophilia A
  
• Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 for Children With Noonan Syndrome
  ClinicalTrials.gov Identifier: NCT00351221 - Terminated
  Noonan Syndrome
  
• Growth Factor to Prevent Oral Mucositis in Patients With Hematologic Cancer
  ClinicalTrials.gov Identifier: NCT00004132 - Completed
  Leukemia; Lymphoma; Multiple Myeloma
  
• Study of Recombinant Human Thrombin for Bleeding During Autologous Skin Grafting
  ClinicalTrials.gov Identifier: NCT00371215 - Active, not recruiting
  Surgical Hemostasis
  
• Vaccines to Treat Metastatic Carcinoma
  ClinicalTrials.gov Identifier: NCT00088413 - Recruiting
  Adenocarcinoma
  
• Vaccine Therapy and Sargramostim With or Without Docetaxel in Treating Patients With Metastatic Lung Cancer or Metastatic Colorectal Cancer
  ClinicalTrials.gov Identifier: NCT00088933 - Active, not recruiting
  Colon Cancer; Non-small cell lung cancer; Rectal Cancer; Small Cell Lung Cancer
  
• Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
  ClinicalTrials.gov Identifier: NCT00262288 - Active, not recruiting
  Genetic Disorders
  
• Recombinant Human Antithrombin (rhAT) in Patients with Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery
  ClinicalTrials.gov Identifier: NCT00110513 - Recruiting
  Antithrombin III Deficiency
  
• Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer
  ClinicalTrials.gov Identifier: NCT00006225 - Active, not recruiting
  Breast Cancer; Leukemia; Lymphoma; Male Breast Cancer; myelodysplastic and myeloproliferative diseases; plasma cell neoplasm
  
• Treatment With Recombinant Human GH in Children With Short Stature Secondary to a Long Term Corticoid Therapy
  ClinicalTrials.gov Identifier: NCT00174187 - Active, not recruiting
  Growth Retardation
  
• Recombinant Human Prolactin for Lactation Induction
  ClinicalTrials.gov Identifier: NCT00181649 - Recruiting
  Relative lactation insufficiency
  
• Neoadjuvant Intravesical Vaccine Therapy in Treating Patients With Bladder Carcinoma Who Are Undergoing Cystectomy
  ClinicalTrials.gov Identifier: NCT00072137 - Recruiting
  Bladder Cancer
  
• Study of Recombinant Interleukin 21 in Combination With Rituxan for Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00347971 - Active, not recruiting
  Lymphoma, Non-Hodgkin
  
• Recombinant Human Relaxin for the Treatment of Decompensated CHF
  ClinicalTrials.gov Identifier: NCT00406575 - Active, not recruiting
  Congestive Heart Failure (CHF)
  
• Recombinant Human Relaxin (rhRlx) in Pregnant Women Scheduled for Induction of Labor
  ClinicalTrials.gov Identifier: NCT00259103 - Active, not recruiting
  Labor, Induced
  
• Study of Recombinant Modified Process Hepatitis B Vaccine in Older Adults
  ClinicalTrials.gov Identifier: NCT00440531 - Active, not recruiting
  Haemophilus Infections; Hepatitis B
  
• One Year Study to Evaluate Three Different Adjuvanted Doses of the Recombinant Plague Vaccine (rF1 and rV Antigens)
  ClinicalTrials.gov Identifier: NCT00246467 - Active, not recruiting
  Plague
  
• Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gout
  ClinicalTrials.gov Identifier: NCT00111657 - Recruiting
  Gout
  
• Evaluate Tolerability of a Recombinant DNA HIV-1 Vaccine in Healthy Adults
  ClinicalTrials.gov Identifier: NCT00187148 - Active, not recruiting
  Human Immunodeficiency Virus; HIV Infections
  
• Single-Blind, Controlled Safety and Immunogenicity Study of Recombinant MVA Virus to Treat HIV Infection
  ClinicalTrials.gov Identifier: NCT00390078 - Active, not recruiting
  HIV Infections
  
• Keratinocyte Growth Factor to Prevent Acute GVHD
  ClinicalTrials.gov Identifier: NCT00031148 - Completed
  Graft-vs-Host Disease
  
• Efficacy and Safety of FVIIa on Rebleeding After Surgery for Spontaneous Intracerebral Hemorrhage
  ClinicalTrials.gov Identifier: NCT00128050 - Recruiting
  Spontaneous Intracerebral Hemorrhage (ICH)
  
• A Prospective, Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia (Aplastic Anemia) Mediated by Erythropoietin Antibodies Among Patients With Chronic Kidney Failure and Subcutaneous Exposure to Recombinant Erythropoietin Products
  ClinicalTrials.gov Identifier: NCT00391287 - Recruiting
  Erythropoietin, Recombinant; Kidney Failure, Chronic; Pure Red-Cell Aplasia; Red-Cell Aplasia, Pure
  
• NGR-TNF in Treating Patients With Advanced Solid Tumors
  ClinicalTrials.gov Identifier: NCT00098943 - Active, not recruiting
  adult solid tumor; Endocrine Cancer; Gastrointestinal Cancer; Head and Neck Cancer; kidney and urinary cancer
  
• High Dose of Activated Recombinant Human Factor VII for Treatment of Mild/Moderate Joint Bleeds in Haemophilia Patients With Inhibitors
  ClinicalTrials.gov Identifier: NCT00571584 - Completed
  Haemophilia
  
• Safety and Efficacy of Recombinant Grass Pollen Allergen Cocktail in the Treatment of Allergic Rhinoconjunctivitis
  ClinicalTrials.gov Identifier: NCT00309036 - Active, not recruiting
  Grass Pollen Allergy
  
• Specific Immunotherapy With Recombinant Birch Pollen Allergen rBet v1-FV
  ClinicalTrials.gov Identifier: NCT00266526 - Active, not recruiting
  Birch Pollen Allergy
  
• Safety and Efficacy of Recombinant Birch Pollen Allergen in the Treatment of Allergic Rhinoconjunctivitis
  ClinicalTrials.gov Identifier: NCT00309062 - Active, not recruiting
  Birch Pollen Allergy
  
• Prepubertal Children with Growth Failure Associated with Primary IGF-1 Deficiency
  ClinicalTrials.gov Identifier: NCT00125164 - Active, not recruiting
  Insulin-Like Growth Factor-1 Deficiency; Primary IGF-1 Deficiency
  
• The Serum Tissue Factor Level in Lung Cancer Patients as a Prognostic Factor
  ClinicalTrials.gov Identifier: NCT00257179 - Recruiting
  Lung Cancer
  
• Stem Cell Factor Medication for Aplastic Anemia
  ClinicalTrials.gov Identifier: NCT00001398 - Completed
  Aplastic Anemia; Pancytopenia
  
• Biological Therapy in Treating Patients With Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00005853 - Active, not recruiting
  Myelodysplastic Syndromes
  
• A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma
  ClinicalTrials.gov Identifier: NCT00002262 - Completed
  Sarcoma, Kaposi; HIV Infections
  
• A Study to Test the Safety of Recombinant Interleukin-2 (rIL-2) in HIV-Infected Children
  ClinicalTrials.gov Identifier: NCT00000849 - Active, not recruiting
  HIV Infections
  
• Vaccine Therapy, GM-CSF, and Interferon Alfa-2b in Treating Patients With Locally Advanced or Metastatic Cancer That Expresses Carcinoembryonic Antigen (CEA)
  ClinicalTrials.gov Identifier: NCT00217373 - Recruiting
  unspecified adult solid tumor, protocol specific
  
• Efficacy and Safety From a Recombinant Folding Variant of Bet v 1
  ClinicalTrials.gov Identifier: NCT00554983 - Recruiting
  Allergy
  
• Safety, Tolerability and Immunogenicity of Recombinant Anthrax Vaccine Compared With Anthrax Vaccine Adsorbed
  ClinicalTrials.gov Identifier: NCT00170469 - Active, not recruiting
  Bacillus Anthracis (Anthrax)
  
• Biological Therapies Following Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Advanced Breast Cancer
  ClinicalTrials.gov Identifier: NCT00005993 - Active, not recruiting
  Lymphoma; Breast Cancer
  
• Study of Subcutaneous Rehydration With Recombinant Human Hyaluronidase for Infants and Children
  ClinicalTrials.gov Identifier: NCT00477152 - Recruiting
  Dehydration
  
• Title: A Phase 2 (a), Dose-Blinded, Block-Randomized, Dose and Schedule Selection Study to Evaluate the Immunogenicity and Safety of the Recombinant Plague Vaccine rF1V in Healthy Volunteers
  ClinicalTrials.gov Identifier: NCT00332956 - Active, not recruiting
  Healthy Volunteers
  
• A Pilot Study of Recombinant Human Relaxin (rhRlx) in Compensated Congestive Heart Failure
  ClinicalTrials.gov Identifier: NCT00259116 - Active, not recruiting
  Heart Failure, Congestive
  
• Can Recombinant Human Intrinsic Factor Be Used for Evaluation of the Vitamin B12 Absorption?
  ClinicalTrials.gov Identifier: NCT00279552 - Completed
  Vitamin B12 Deficiency
  
• Total Therapy II
  ClinicalTrials.gov Identifier: NCT00083551 - Active, not recruiting
  Multiple Myeloma
  
• Effects of Epidermal Growth Factor Receptor Inhibitors on the Skin of Cancer Patients Receiving Epidermal Growth Factor Receptor Inhibitors
  ClinicalTrials.gov Identifier: NCT00483457 - Recruiting
  Unspecified Adult Solid Tumor, Protocol Specific
  
• Study of Recombinant Porcine Factor VIII (FVIII) in Hemophilia and Inhibitors to FVIII
  ClinicalTrials.gov Identifier: NCT00245245 - Completed
  Hemophilia A
  
• A Study of the Efficacy and Safety of Highly Purified Menotrophin Versus Recombinant Follitropin Alfa
  ClinicalTrials.gov Identifier: NCT00257556 - Recruiting
  Infertility
  
• Safety, Tolerability and Pharmacodynamic Effects of Sublingual Immunotherapy (Tablets) With Recombinant Bet v1
  ClinicalTrials.gov Identifier: NCT00396149 - Recruiting
  Allergy
  
• Efficacy and Safety Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients in Canada With Hemophilia A - A Continuation of Baxter Study 060101
  ClinicalTrials.gov Identifier: NCT00189982 - Completed
  Hemophilia A