Article: Famciclovir

Famciclovir
Systematic (IUPAC) name
[2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)-butyl] acetate
Identifiers
CAS number	104227-87-4
ATC code	J05AB09 S01AD07
PubChem	3324
DrugBank	APRD00600
Chemical data
Formula	C14H19N5O4
Mol. weight	321.332 g/mol
Pharmacokinetic data
Bioavailability	75–77%
Protein binding	20-25%
Metabolism	Hepatic, circulation, intestinal wall (to penciclovir)
Half life	2–2.3 hours
Excretion	Renal, faecal
Therapeutic considerations
Pregnancy cat.	B1 (Au), B (U.S.)
Legal status	S4 (Au), POM (UK), ℞-only (U.S.)
Routes	Oral

Famciclovir (INN) (IPA: [pɛnˈsaɪklovir]) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is a prodrug form of penciclovir with improved oral bioavailability. Famciclovir is marketed under the trade name Famvir (Novartis).

See also

• Penciclovir

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