Fulvestrant |
Faslodex |
Fulvestrant, also known as ICI 182,780, is a drug treatment of hormone receptor positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.[1] It is administered as a once-monthly injection. Fulvestrant is marketed by AstraZeneca with the brand name Faslodex. ...
Wikipedia - [full article]
Fulvestrant Clinical Trials
- A Comparison of the Efficacy and Tolerability of Fulvestrant (FASLODEX™) in Women with Breast Cancer
ClinicalTrials.gov Identifier: NCT00099437 - Active, not recruiting
Breast Cancer
- Enzastaurin Plus Fulvestrant vs. Placebo Plus Fulvestrant in Breast Cancer
ClinicalTrials.gov Identifier: NCT00451555 - Recruiting
Breast Neoplasms
- A Pilot Clinical Trial to Evaluate the Biological Activity of Fulvestrant in Breast Ductal Carcinoma in Situ (DCIS)
ClinicalTrials.gov Identifier: NCT00183963 - Not yet recruiting
Breast Carcinoma
- Fulvestrant or Tamoxifen in Treating Postmenopausal Women Who Are Undergoing Surgery for Ductal Carcinoma in Situ of the Breast
ClinicalTrials.gov Identifier: NCT00126464 - Active, not recruiting
intraductal breast carcinoma; breast cancer in situ
- Anastrozole and Gefitinib Compared With Fulvestrant and Gefitinib in Treating Postmenopausal Women With Recurrent or Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00057941 - Active, not recruiting
recurrent breast cancer; stage IV breast cancer
- Anastrozole With or Without Fulvestrant as First-Line Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00075764 - Recruiting
stage IV breast cancer; recurrent breast cancer
- Tipifarnib and Fulvestrant as Second-Line Therapy in Treating Postmenopausal Women With Hormone Receptor-Positive Inoperable Locally Advanced or Metastatic Breast Cancer With Progressive Disease After Previous First-Line Endocrine Therapy
ClinicalTrials.gov Identifier: NCT00082810 - Active, not recruiting
recurrent breast cancer; stage IIIB breast cancer; stage IIIC breast cancer; stage IV breast cancer
- Fulvestrant in Treating Patients With Recurrent, Persistent, or Metastatic Endometrial Cancer
ClinicalTrials.gov Identifier: NCT00006903 - Recruiting
stage IV endometrial cancer; recurrent endometrial cancer
- Fulvestrant and/or Trastuzumab in Treating Postmenopausal Women With Stage IV Breast Cancer
ClinicalTrials.gov Identifier: NCT00138125 - Recruiting
stage IV breast cancer; recurrent breast cancer
- Gefitinib With or Without Fulvestrant in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00100854 - Active, not recruiting
stage IIIB non-small cell lung cancer; stage IV non-small cell lung cancer; recurrent non-small cell lung cancer
- Fulvestrant in Treating Patients With Advanced Prostate Cancer
ClinicalTrials.gov Identifier: NCT00244998 - Active, not recruiting
Prostate Cancer
- @FAME - Anastrozole and Fulvestrant Compared to Anastrozole as Adjuvant Treatment of Postmenopausal Patients With Breast Cancer
ClinicalTrials.gov Identifier: NCT00357110 - Active, not recruiting
Breast Cancer
- FINDER I - A Clinical Trial to Compare Efficacy and Tolerability of Fulvestrant 250mg, 250mg (Plus 250mg Loading Regimen) and 500mg
ClinicalTrials.gov Identifier: NCT00305448 - Active, not recruiting
Advanced Breast Cancer; Metastatic Breast Cancer
- A Clinical Trial to Compare Efficacy and Tolerability of Faslodex With Arimidex in Patients With Advanced Breast Cancer
ClinicalTrials.gov Identifier: NCT00274469 - Active, not recruiting
Metastatic Breast Cancer
- FACT - Anastrozole Monotherapy Versus Maximal Oestrogen Blockade With Anastrozole and Fulvestrant Combination Therapy
ClinicalTrials.gov Identifier: NCT00256698 - Recruiting
Breast Cancer
- FASLODEX and AROMASIN in Hormone Receptor Positive Postmenopausal Women with Advanced Breast Cancer
ClinicalTrials.gov Identifier: NCT00065325 - Active, not recruiting
Breast Neoplasms; Metastases, Neoplasm
- Fulvestrant With or Without Anastrozole or Exemestane Alone in Treating Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00253422 - Recruiting
Breast Cancer
- Exemestane in Combination With Fulvestrant in Postmenopausal Women With Hormone Sensitive Advanced Breast Cancer
ClinicalTrials.gov Identifier: NCT00201864 - Recruiting
Breast Cancer
- Fulvestrant (FASLODEX™) as a Treatment in Postmenopausal Women with Estrogen Receptor Positive Breast Cancer
ClinicalTrials.gov Identifier: NCT00093002 - Completed
Breast Cancer
- Fulvestrant in Treating Patients With Recurrent Prostate Cancer
ClinicalTrials.gov Identifier: NCT00217464 - Recruiting
Prostate Cancer
- Fulvestrant for the Treatment of Recurrent or Metastatic Endometrial Carcinoma.
ClinicalTrials.gov Identifier: NCT00334295 - Recruiting
Endometrial Carcinoma
- Bevacizumab Given With Either Anastrozole or Fulvestrant With Trastuzumab for Postmenopausal Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00405938 - Recruiting
Breast Cancer; Breast Neoplasms
- Phase II Trial of Capecitabine Plus Fulvestrant in First Line Treatment of Hormone Receptor Positive Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00534417 - Recruiting
Metastatic Breast Cancer
- Fulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-Positive and Expresses HER2
ClinicalTrials.gov Identifier: NCT00390455 - Recruiting
Breast Cancer
- Fulvestrant in Hormone Refractory Prostate Cancer
ClinicalTrials.gov Identifier: NCT00476645 - Recruiting
Prostate Cancer
- FINDER II - A Clinical Trial to Compare Efficacy and Tolerability of Fulvestrant 250mg, 250mg Plus 250mg Loading Regimen and 500mg
ClinicalTrials.gov Identifier: NCT00313170 - Recruiting
Advanced Breast Cancer; Metastatic Breast Cancer
- Fulvestrant (Faslodex) + Anastrozol (Arimidex) vs Anastrozol
ClinicalTrials.gov Identifier: NCT00543127 - Not yet recruiting
Breast Cancer
- Randomized, Double Blind Multicenter Phase II Study of Time to Progression on Fulvestrant in Combination With Erlotinib or Placebo in Hormone Receptor-Positive Metastatic Breast Cancer (MBC) Subjects Who Progressed on First Line Hormonal Therapy
ClinicalTrials.gov Identifier: NCT00570258 - Recruiting
Metastatic Breast Cancer
- AZD2171 in Addition to Fulvestrant in Patients With Advanced Breast Cancer
ClinicalTrials.gov Identifier: NCT00454805 - Recruiting
Advanced Breast Cancer
- Phase 2 Study of Combined Fulvestrant and RAD001 in Advanced/Metastatic Breast Cancer After Aromatase Inhibitor Failure
ClinicalTrials.gov Identifier: NCT00570921 - Not yet recruiting
Breast Cancer
- ICI 182780 in Treating Women With Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00012025 - Active, not recruiting
stage IV breast cancer; recurrent breast cancer; stage IIIB breast cancer; stage IIIC breast cancer
- Fulvestrant in Premenopausal Women with Hormone Receptor-Positive Breast Cancer
ClinicalTrials.gov Identifier: NCT00146601 - Completed
Invasive Breast Cancer; Stage IV Breast Cancer; Hormone Receptor-Positive Breast Cancer
- Fulvestrant and Bevacizumab in Treating Patients With Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00423917 - Suspended
Breast Cancer
- ICI 182780 in Treating Women With Stage I or Stage II Primary Breast Cancer
ClinicalTrials.gov Identifier: NCT00010153 - Completed
stage I breast cancer; stage II breast cancer

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