The purpose of this study is to look at the benefits of tiotropium, an approved drug for the treatment of bronchospasm associated with COPD (chronic obstructive pulmonary disease), in a population of patients with COPD who are of African American descent.

Condition	Treatment or Intervention	Phase
Chronic Obstructive Pulmonary Disease	Drug: Tiotropium Bromide Inhalation Powder	Phase IV

Further Study Details: 

Ages Eligible for Study:  40 Years and above,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Male or female of African descent
• 40 years of age or older
• Diagnosis of COPD
• History of smoking at least one pack per day for at least 10 years
• Currently experiencing shortness of breath at least with exertion

Exclusion Criteria:

• Asthma
• Recent myocardial infarction or hospitalization for congestive heart failure

Craig S. Conoscenti, MD      203-798-4764    cconosce@rdg.boehringer-ingelheim.com

Alabama
      Birmingham VA Medical Center, Birmingham,  Alabama,  35294,  United States; Recruiting
      Cooper Green Hospital, Birmingham,  Alabama,  35233,  United States; Recruiting
      UAB Medical Center, Birmingham,  Alabama,  35294,  United States; Recruiting
California
      VA Greater Los Angeles Health Care System, Sepulveda,  California,  91343,  United States; Recruiting
      UCLA David Geffen School of Medicine, Los Angeles,  California,  90024,  United States; Recruiting
Connecticut
      Waterbury Pulmonary Associates, Waterbury,  Connecticut,  06708,  United States; Recruiting
      Yale School of Medicine, New Haven,  Connecticut,  06502,  United States; Recruiting
Florida
      The Bay Pines Foundation-VAMC, Bay Pines,  Florida,  33744,  United States; Recruiting
      Emerald Coast Research Association, Panama City,  Florida,  32405,  United States; Recruiting
Georgia
      Emory Crawford Long, Atlanta,  Georgia,  30308,  United States; Recruiting
Louisiana
      LSU MC-Shreveport Div Pulmonary-Critical Care Medicine, Shreveport,  Louisiana,  71103,  United States; Recruiting
      LSU School of Medicine, New Orleans,  Louisiana,  70112,  United States; Recruiting
New York
      Bronx VA Pulmonary Section, Bronx,  New York,  10468,  United States; Recruiting
North Carolina
      Pulmonary and Critical Care, Greenville,  North Carolina,  27834,  United States; Recruiting
Pennsylvania
      Arcuri Clinical Research, Philadelphia,  Pennsylvania,  19142,  United States; Not yet recruiting
      Temple University Hospital, Philadelphia,  Pennsylvania,  19140,  United States; Recruiting
South Carolina
      Spartanburgh Pharmceutical Research, Spartanburg,  South Carolina,  29307,  United States; Recruiting
      Low Country Lung and Critical Care P.A., Charleston,  South Carolina,  29406,  United States; Recruiting
Texas
      Ben Taub Gen. Hospital Baylor College of Medecine, Houston,  Texas,  77030,  United States; Recruiting
      M.E. D. VA Medical Center Pulmonary Section, Houston,  Texas,  77030,  United States; Recruiting

Study ID Numbers:  BI-205.294
Record last reviewed:  March 2005
Last Updated:  April 1, 2005
Record first received:  March 31, 2005
ClinicalTrials.gov Identifier:  NCT00106821
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-04-08