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Ofloxacin

Floxin

Article: Ofloxacin

Image:Ofloxacin.png
Ofloxacin
Systematic (IUPAC) name
(+/-)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)- 7-oxo-7H-pyrido [1,2,3-de]-1, 4-benzoxazine-6-carboxylic acid
Identifiers
CAS number 82419-36-1
ATC code J01MA01 J01MA02, J01MA12, S01AX11, S01AX13, S01AX19, S03AA07
PubChem 4583
DrugBank APRD00502
Chemical data
Formula C18H20FN3O4
Mol. weight 361.368 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 32%
Metabolism  ?
Half life 9 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C (US)
Legal status

Perscription Only (US)
Routes topical (ear drops)

Ofloxacin sold under the brand name Floxin in the US. It is a quinolone antibiotic. Ofloxacin is the racemic mixture of the chiral compound. The biologically active enantiomer is sold separately under the name of levofloxacin. It is an alternative treatment to ciprofloxacin for anthrax.



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July 25, 2008


Page Updated: July 22, 2006
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