Floxuridine |
Fluorodeoxyuridine; FUDR |
Image:Floxuridine.png Floxuridine Systematic (IUPAC) name 5-fluoro-1-[4-hydroxy-5- (hydroxymethyl)tetrahydrofuran-2-yl]- 1H-pyrimidine-2,4-dione Identifiers CAS number 50-91-9 ATC code ? PubChem 5790 DrugBank APRD00692 Chemical data Formula C9H11FN2O5 Mol. weight 246.193 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes & ...
Wikipedia - [full article]
Floxuridine Clinical Trials
- Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00002842 - Active, not recruiting
stage IV colon cancer; Stage IV rectal cancer; recurrent colon cancer; recurrent rectal cancer; liver metastases
- Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00361842 - Active, not recruiting
Colorectal Neoplasms
- Oxaliplatin and Capecitabine With or Without Hepatic Arterial Infusion of Floxuridine in Patients Who Are Undergoing Surgery and/or Ablation for Liver Metastases From Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00268463 - Active, not recruiting
Liver Metastases; Stage IV Colon Cancer; Stage IV Rectal Cancer; Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum
- Floxuridine and Dexamethasone as a Hepatic Arterial Infusion and Bevacizumab in Treating Patients With Primary Liver Cancer That Cannot be Removed by Surgery
ClinicalTrials.gov Identifier: NCT00410956 - Recruiting
Liver Cancer
- Study of 5-Fluorouracil and Leucovorin and Intra-Abdominal Floxuridine Chemoradiation in Patients With Fully Resected Locally Advanced Gastric Adenocarcinoma
ClinicalTrials.gov Identifier: NCT00183911 - Recruiting
Gastric Adenocarcinoma; Gastric Cancer
- Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy and Bevacizumab in Treating Patients With Colorectal Cancer That Has Spread to the Liver
ClinicalTrials.gov Identifier: NCT00492999 - Recruiting
Colorectal Cancer; Metastatic Cancer
- Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
ClinicalTrials.gov Identifier: NCT00026234 - Active, not recruiting
Colon Cancer; liver metastases; Rectal Cancer
- Intraperitoneal Floxuridine in Gastric Carcinoma
ClinicalTrials.gov Identifier: NCT00058916 - Recruiting
Stomach Neoplasms
- Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases from Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00008294 - Active, not recruiting
Colon Cancer; liver metastases; Rectal Cancer
- Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer
ClinicalTrials.gov Identifier: NCT00005049 - Active, not recruiting
female reproductive cancer; Gastrointestinal Cancer; unclassified and other cancer
- Hepatic Arterial Infusion W/Floxuridine & Dexamethasone Combination W/Chemo W/W/Out Bevacizumab for Hepatic Mets From Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00200200 - Recruiting
Hepatic Metastases; Colorectal Cancer
- Combination Chemotherapy Before and After Surgery in Treating Patients With Stomach Cancer
ClinicalTrials.gov Identifier: NCT00002783 - Active, not recruiting
stage III gastric cancer; stage II gastric cancer; stage IV gastric cancer; adenocarcinoma of the stomach
- Floxuridine, Dexamethasone, and Irinotecan After Surgery in Treating Patients With Liver Metastases From Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00003753 - Completed
Colon Cancer; liver metastases; Rectal Cancer
- Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver
ClinicalTrials.gov Identifier: NCT00004142 - Active, not recruiting
recurrent colon cancer; liver metastases; Stage IV rectal cancer; recurrent rectal cancer; stage IV colon cancer
- Combination Chemotherapy Followed by Surgery in Treating Patients With Stomach Cancer
ClinicalTrials.gov Identifier: NCT00004103 - Active, not recruiting
stage I gastric cancer; stage II gastric cancer; stage III gastric cancer; stage IV gastric cancer
- Combination Chemotherapy Followed by Surgery and Intraperitoneal Chemotherapy in Treating Patients With Locally Advanced Stomach Cancer
ClinicalTrials.gov Identifier: NCT00006038 - Active, not recruiting
stage III gastric cancer; stage III esophageal cancer; Adenocarcinoma of the Esophagus; stage II gastric cancer; stage IV gastric cancer; ...
- Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00059930 - Recruiting
Colon Cancer; liver metastases; Rectal Cancer
- Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum
ClinicalTrials.gov Identifier: NCT00005860 - Completed
Pancreatic Cancer; Gastric Cancer; Colorectal Cancer; adult primary liver cancer; ovarian epithelial cancer; Colon Cancer
- Hepatic Arterial Infusion With Floxuridine and Systemic Irinotecan After Surgery in Treating Patients With Hepatic (Liver) Metastases From Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00063960 - Completed
stage IV colon cancer; adenocarcinoma of the colon; adenocarcinoma of the rectum; Stage IV rectal cancer; liver metastases
- Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Treating Patients With Primary Liver Cancer That Cannot Be Removed By Surgery
ClinicalTrials.gov Identifier: NCT00310102 - Completed
Liver Cancer
- Local and Systemic Chemotherapy with or without Isolated Liver Perfusion for Patients with Inoperable Metastatic Colorectal Cancers of the Liver
ClinicalTrials.gov Identifier: NCT00011427 - Completed
Colorectal Cancer
- A Phase I Study of Isolated Hepatic Perfusion with Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver
ClinicalTrials.gov Identifier: NCT00001576 - Completed
Colorectal Neoplasm; Liver Neoplasm; Neoplasm Metastasis
- Combination Chemotherapy in Treating Patients With Liver Metastases from Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00002716 - Completed
Colon Cancer; liver metastases; Rectal Cancer

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