Article: Tiagabine

Tiagabine
Systematic (IUPAC) name
(3S)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl] piperidine-3-carboxylic acid
Identifiers
CAS number	115103-54-3
ATC code	N03AG06
PubChem	60648
DrugBank	APRD00344
Chemical data
Formula	C20H25NO2S2
Mol. weight	375.55 g/mol
Pharmacokinetic data
Bioavailability	90%
Protein binding	96%
Metabolism	Hepatic (CYP450 system)
Half life	7-9 hours
Excretion	Fecal and renal
Therapeutic considerations
Pregnancy cat.	B3 (Au), C (U.S.)
Legal status	POM (UK), ℞-only (U.S.)
Routes	Oral

Tiagabine (IPA: [ˌtɪəgəˈbin]) is an anti-convulsive medication produced by Cephalon Inc. and marketed under the brand name Gabitril®. The medication is also used in the treatment for panic disorder as are a few other anticonvulsants.

Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.