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Granisetron |
Kytril |
Granisetron Systematic (IUPAC) name 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)- indazole-3-carboxamide Identifiers CAS number 109889-09-0 ATC code A04AA02 PubChem 3510 DrugBank APRD01002 Chemical data Formula C18H24N4O Mol. weight 312.41 g/mol Pharmacokinetic data Bioavailability 60% Protein binding 65% Metabolism Hepatic Half life 3–14 hours Excretion Renal 11–12%, faecal 38% Therapeutic considerations Pregnancy cat. B1 (Au), L ...
Wikipedia - [full article]
Granisetron Clinical Trials
- Granisetron to Prevent Nausea and Vomiting After Chemotherapy in Patients With Malignant Disease
ClinicalTrials.gov Identifier: NCT00005024 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy
ClinicalTrials.gov Identifier: NCT00231478 - Active, not recruiting
Post-Operative Nausea and Vomiting
- A Study of Ramosetron Plus DX, Dexamethasone, Compared to Granisetron Plus DX for the Prevention of Vomiting and Nausea.
ClinicalTrials.gov Identifier: NCT00272285 - Active, not recruiting
Vomiting; Nausea
- Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma
ClinicalTrials.gov Identifier: NCT00004219 - Active, not recruiting
stage I testicular cancer; testicular seminoma; nausea and vomiting
- The Antigagging Effect of Granisetron (Kytril), an Antiemetic Drug, in Dental Situations
ClinicalTrials.gov Identifier: NCT00502437 - Not yet recruiting
Antiggaging Effect; Antiemetic; Granisetron; Gag Reflex; Dental Situations
- To Study the Safety and Effectiveness of a Granisetron Patch to Treat Chemotherapy-Induced Nausea and Vomiting (CINV)
ClinicalTrials.gov Identifier: NCT00273468 - Not yet recruiting
Chemotherapy-Induced Nausea and Vomiting
- Drugs to Reduce the Side Effects of Chemotherapy
ClinicalTrials.gov Identifier: NCT00003213 - Active, not recruiting
solid tumor; Nausea; Vomiting
- Comparative Study of Palonosetron With Granisetron as a Control in Patients Receiving Highly Emetogenic Chemotherapy
ClinicalTrials.gov Identifier: NCT00359567 - Recruiting
Chemotherapy-Induced Nausea and Vomiting
- Aprepitant Plus Palonosetron Versus Granisetron in the Prevention of Nausea and the Emesis Induced by Chemotherapy in Patients Treated With Haematopoietic Progenitors
ClinicalTrials.gov Identifier: NCT00415103 - Recruiting
Nausea; Emesis
- Granisetron, Dexamethasone, Prochlorperazine, Aprepitant, and Palonosetron in Preventing Nausea in Women Undergoing Chemotherapy for Breast Cancer
ClinicalTrials.gov Identifier: NCT00475085 - Recruiting
Breast Cancer; Nausea and Vomiting
- The Pharmacokinetic Interaction Between Oral Casopitant and Oral Dolasetron, Granisetron or Rosiglitazone in Subjects
ClinicalTrials.gov Identifier: NCT00511823 - Recruiting
Postoperative Nausea and Vomiting; Chemotherapy-Induced Nausea and Vomiting
- Acupressure and Acustimulation Wrist Bands for the Prevention of Nausea and Vomiting Caused by Chemotherapy
ClinicalTrials.gov Identifier: NCT00003817 - Active, not recruiting
unspecified adult solid tumor, protocol specific; Quality of Life; nausea and vomiting
- Aprepitant, Granisetron, and Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Cyclophosphamide Before a Stem Cell Transplant
ClinicalTrials.gov Identifier: NCT00293384 - Recruiting
Brain and Central Nervous System Tumors; Breast Cancer; Chronic Myeloproliferative Disorders; Gestational Trophoblastic Tumor; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases; Nausea and Vomiting; Ovarian Cancer; Testicular Germ Cell Tumor
- Randomized Crossover Pharmacokinetic Evaluation of Subcutaneous Versus Intravenous Granisetron in Cancer Patients
ClinicalTrials.gov Identifier: NCT00450853 - Completed
Vomiting
- Ginger in Treating Nausea in Patients Receiving Chemotherapy for Cancer
ClinicalTrials.gov Identifier: NCT00040742 - Recruiting
nausea and vomiting; unspecified adult solid tumor, protocol specific
- Comparison of Antiemetic Drugs in Preventing Delayed Nausea After Chemotherapy in Patients With Cancer
ClinicalTrials.gov Identifier: NCT00020657 - Completed
unspecified adult solid tumor, protocol specific; nausea and vomiting; Quality of Life
Resources
- Granisetron (Drug Digest)
- Kytril (Drug Digest)
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