Not Signed In -
Haloperidol Tablets |
Haldol Tablets |
Clinical Trial: Maintenance Treatment Vs. Stepwise Drug Discontinuation in First-Episode Schizophrenia
This study is no longer recruiting patients.
|
Purpose
| Condition | Intervention | Phase |
|---|---|---|
| Schizophrenia Psychoses | Drug: Haloperidol Risperidone | Phase IV |
MedlinePlus related topics: Mental Health; Schizophrenia
Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title: Maintenance Treatment Vs. Stepwise Drug Discontinuation After One Year of Maintenance Treatment in First-Episode Schizophrenia
Secondary Outcomes: 1 year course regarding psychopathology; social and cognitive functioning; side-effects; drop-out; quality of life
Expected Total Enrollment: 71
Study start: November 2001; Study completion: December 2006
Last follow-up: April 2006; Data entry closure: September 2006
Eligibility
Inclusion Criteria:
- First-episode in schizophrenia (according ICD-10 F20)
- Age between 18 and 55
- Informed consent
- One year neuroleptic maintenance treatment
- Reaching stable course
Exclusion Criteria:
- Residence outside of the catchment area
- Legal reasons
- Insufficient knowledge of the german language
- Substance abuse or addiction
- Pregnancy
- Serious physical illness
- Organic brain disease
- Contraindication to neuroleptic treatment
Location Information
Germany, North Rhine-Westphalia
German Research Network on Schizophrenia, Department of Psychiatry and Psychotherapy at the Heinrich-Heine-University Düsseldorf, Düsseldorf, North Rhine-Westphalia, 40629, Germany
Wolfgang Gaebel, Professor, Study Chair, Department of Psychiatry and Psychotherapy at the Heinrich-Heine-University of Düsseldorf, Rhineland State Clinics Düsseldorf, Bergische Landstraße 2, 40629 Düsseldorf, Germany
More Information
Publications
Gaebel W, Moller HJ, Buchkremer G, Ohmann C, Riesbeck M, Wolwer W, Von Wilmsdorff M, Bottlender R, Klingberg S. Pharmacological long-term treatment strategies in first episode schizophrenia--study design and preliminary results of an ongoing RCT within the German Research Network on Schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2004 Apr;254(2):129-40.
Last Updated: September 11, 2005
Record first received: September 7, 2005
ClinicalTrials.gov Identifier: NCT00159120
Health Authority: Germany: Federal Institute for Drugs and Medicinal Devices
ClinicalTrials.gov processed this record on 2005-09-13
Resources
- Haldol Tablets (Drug Digest)
- Haloperidol Tablets (Drug Digest)
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