Idarubicin |
Idamycin |
Idarubicin Systematic (IUPAC) name 9-acetyl-7-( 4-amino-5-hydroxy-6-methyl- tetrahydropyran-2-yl) oxy-6,9, 11-trihydroxy- 7,8,9,10-tetrahydrotetracene-5,12-dione Identifiers CAS number 58957-92-9 ATC code L01DB06 PubChem 42890 DrugBank APRD00126 Chemical data Formula C26H27NO9 Mol. weight 497.494 g/mol Pharmacokinetic data Bioavailability ? Protein binding 97% Metabolism ? Half life 22 hours Excretion ? Therapeutic considerations P ...
Wikipedia - [full article]
Idarubicin Clinical Trials
- Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002989 - Active, not recruiting
Leukemia; Lymphoma; Multiple Myeloma
- Pravastatin, Idarubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00107523 - Active, not recruiting
adult acute myeloid leukemia
- Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00096122 - Active, not recruiting
adult acute erythroid leukemia; adult acute monoblastic and acute monocytic leukemia; adult acute myeloid leukemia; ...
- VELCADE in Combination With Idarubicin and Cytosine Arabinoside in Patients With Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00505700 - Active, not recruiting
Leukemia
- Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma
ClinicalTrials.gov Identifier: NCT00193973 - Active, not recruiting
Primary Central Nervous System Lymphoma
- Idarubicin, Cytarabine, and Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia Secondary to Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00077116 - Active, not recruiting
adult acute myeloid leukemia; Chronic Myelomonocytic Leukemia; Myelodysplastic Syndromes
- Phase I Using Velcade & Idarubicin in Elderly and Relapsed AML
ClinicalTrials.gov Identifier: NCT00382954 - Recruiting
Acute Myelogenous Leukemia
- Salvage Therapy With Idarubicin in Relapsing CNS Lymphoma
ClinicalTrials.gov Identifier: NCT00210366 - Recruiting
Lymphoma, B-Cell
- Idarubicin and High-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00528398 - Recruiting
Leukemia
- Tretinoin and Arsenic Trioxide With or Without Idarubicin in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00528450 - Recruiting
Leukemia
- Lestaurtinib, Cytarabine, and Idarubicin in Treating Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00469859 - Recruiting
Leukemia
- Arsenic Trioxide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00093483 - Recruiting
adult acute erythroid leukemia; adult acute monoblastic and acute monocytic leukemia; adult acute myeloid leukemia; secondary acute myeloid leukemia
- Risk-Adapted Therapy of Acute Myeloid Leukemia of Adults (18-60 Years) According to the Cytogenetic Result
ClinicalTrials.gov Identifier: NCT00146120 - Active, not recruiting
Acute Myeloid Leukemia
- Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002532 - Active, not recruiting
recurrent adult acute lymphoblastic leukemia
- Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006)
ClinicalTrials.gov Identifier: NCT00542971 - Recruiting
AML; High-Risk MDS; Acute Myeloid Leukemia; High-Risk Myelodysplastic Disorder
- Study Evaluating the Addition of Amifostine (Ethyol®) to Idarubicin and Cytosine Arabinoside in Older Patients with Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00086099 - Active, not recruiting
Leukemia; Acute Myeloid Leukemia
- Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00002816 - Active, not recruiting
Quality of Life; recurrent childhood acute lymphoblastic leukemia
- Interferon-alfa With or Without Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002868 - Active, not recruiting
chronic phase chronic myelogenous leukemia
- Dosing Study of Ara-C/EL625/Idarubicin in Refractory and Relapsed AML
ClinicalTrials.gov Identifier: NCT00074737 - Completed
Acute Myelogenous Leukemia
- Treatment of Acute Promyelocytic Leukemia With All-Trans Retinoic Acid (ATRA) and Idarubicin (AIDA)
ClinicalTrials.gov Identifier: NCT00465933 - Recruiting
Acute Promyelocytic Leukemia
- Vorinostat and Idarubicin in Treating Patients With Relapsed or Refractory Leukemia or Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00331513 - Recruiting
Leukemia; Myelodysplastic Syndromes
- Combination Chemotherapy in Treating Patients With Lymphoma
ClinicalTrials.gov Identifier: NCT00002835 - Active, not recruiting
Lymphoma
- Thalidomide, Cyclophosphamide, Oral Idarubicin and Dexamethasone (T-CID) in Patients with Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00124813 - Recruiting
Multiple Myeloma
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002517 - Active, not recruiting
Myeloid Leukemia; Myelodysplastic Syndromes; Refractory Anemia
- Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00003783 - Active, not recruiting
L2 childhood acute lymphoblastic leukemia; untreated childhood acute lymphoblastic leukemia; L1 childhood acute lymphoblastic leukemia; ...
- Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002833 - Active, not recruiting
Chronic Myelogenous Leukemia; Graft vs Host Disease; Philadelphia chromosome; Myeloid Leukemia; Refractory Anemia; Chronic Myelomonocytic Leukemia
- Combination Chemotherapy in Treating Children With Relapsed or Refractory Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00003729 - Active, not recruiting
L2 childhood acute lymphoblastic leukemia; L1 childhood acute lymphoblastic leukemia; recurrent childhood acute lymphoblastic leukemia
- Standard Idarubicin and Cytarabine for the Treatment of Acute Myeloid Leukemia (AML)
ClinicalTrials.gov Identifier: NCT00422591 - Recruiting
Leukemia; Acute Myeloid Leukemia; AML
- Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Myelofibrosis
ClinicalTrials.gov Identifier: NCT00006367 - Active, not recruiting
idiopathic myelofibrosis; Polycythemia Vera; Essential Thrombocythemia; Agnogenic Myeloid Metaplasia
- Cladribine, Cytarabine and Idarubicin in Patients with Relapsed Acute Myelocytic Leukemia (AML)
ClinicalTrials.gov Identifier: NCT00126321 - Recruiting
Leukemia, Myelocytic, Acute
- Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00005823 - Active, not recruiting
Acute Myeloid Leukemia; adult acute monoblastic and acute monocytic leukemia; atypical chronic myeloid leukemia; Chronic Myelomonocytic Leukemia; ...
- Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002658 - Active, not recruiting
Myeloid Leukemia; Neutropenia
- Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002926 - Active, not recruiting
Myelodysplastic Syndromes; Myeloid Leukemia; Refractory Anemia; Refractory Cytopenia
- Chemotherapy With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00052299 - Active, not recruiting
adult acute monoblastic and acute monocytic leukemia; adult acute myeloid leukemia; secondary acute myeloid leukemia
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002701 - Active, not recruiting
untreated adult acute myeloid leukemia; adult acute promyelocytic leukemia (M3)
- Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00003603 - Active, not recruiting
refractory plasma cell neoplasm; stage I multiple myeloma; stage II multiple myeloma; stage III multiple myeloma
- Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002549 - Active, not recruiting
adult acute myelomonocytic leukemia (M4); untreated adult acute myeloid leukemia; adult acute differentiated monocytic leukemia (M5b); ...
- Combination Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00003602 - Active, not recruiting
untreated adult acute myeloid leukemia; refractory anemia with excess blasts; refractory anemia with excess blasts in transformation; ...
- Gemtuzumab Ozogamicin With or Without Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00006122 - Active, not recruiting
untreated adult acute myeloid leukemia; adult acute differentiated monocytic leukemia (M5b); ...
- Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002719 - Active, not recruiting
adult acute myelomonocytic leukemia (M4); untreated adult acute myeloid leukemia; adult acute differentiated monocytic leukemia (M5b); ...
- Donor Lymphocytes to Prevent Graft-Versus-Host Disease in Patients With Chronic Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00004878 - Active, not recruiting
accelerated phase chronic myelogenous leukemia; Graft Versus Host Disease; Philadelphia chromosome positive chronic myelogenous leukemia; ...
- Monoclonal Antibody Therapy and Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia in Remission
ClinicalTrials.gov Identifier: NCT00002609 - Active, not recruiting
childhood acute myeloid leukemia in remission; childhood acute promyelocytic leukemia (M3); adult acute myeloid leukemia in remission; ...
- Chemotherapy in Treating Patients With Newly Diagnosed Acute or Chronic Myelogenous Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002800 - Active, not recruiting
accelerated phase chronic myelogenous leukemia; untreated adult acute myeloid leukemia; de novo myelodysplastic syndrome; ...
- Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002761 - Active, not recruiting
relapsing chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia; chronic phase chronic myelogenous leukemia
- Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00016159 - Active, not recruiting
adult acute myeloid leukemia in remission; childhood acute myeloid leukemia in remission; adult acute promyelocytic leukemia (M3); ...
- Combination Chemotherapy in Treating Patients With Relapsed Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00003758 - Active, not recruiting
acute leukemia; childhood cancer; hematopoietic/lymphoid cancer; Cancer; Leukemia; cellular diagnosis, childhood acute myeloid leukemia; ...
- Clofarabine Combinations in Relapsed/Refractory AML, MDS and Myeloid Blast Phase CML
ClinicalTrials.gov Identifier: NCT00067028 - Recruiting
Acute Myeloid Leukemia; Myelodysplastic Syndrome; Chronic Myeloid Leukemia
- Chemotherapy, Interferon, and Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002771 - Active, not recruiting
chronic phase chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia; ...
- High Dose Chemotherapy, Peripheral Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002945 - Active, not recruiting
adult acute myelomonocytic leukemia (M4); untreated adult acute myeloid leukemia; adult acute monocytic leukemia (M5); ...
- Chemotherapy, Biological Therapy, and/or Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00025402 - Active, not recruiting
chronic phase chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia; ...
- Randomized Phase Iii-Study On Valproic Acid In Combination With All-Trans Retinoic Acid, Standard Induction- And Consolidation Therapy In Older Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00151255 - Recruiting
Acute myeloid leukemia, age > 60 years
- Randomized Phase Ii-Study On Valproic Acid, All-Trans Retinoic Acid And Their Combination In Induction And Consolidation Therapy As Well As Pegfilgrastim After Consolidation Therapy In Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00151242 - Recruiting
Acute Myeloid Leukemia
- Combination Chemotherapy Plus Biological Therapy in Treating Patients With Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00003405 - Active, not recruiting
untreated adult acute myeloid leukemia; childhood acute megakaryocytic leukemia (M7); adult acute differentiated monocytic leukemia (M5b); ...
- Bevacizumab, Idarubicin, and Cytarabine in Treating Patients With Blast Phase Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00023920 - Completed
blastic phase chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia
- Combination Chemotherapy With or Without Interferon alfa in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003639 - Active, not recruiting
stage III grade II follicular mixed cell lymphoma; stage IV grade II follicular mixed cell lymphoma; ...
- Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00096148 - Completed
adult acute erythroid leukemia; adult acute monoblastic and acute monocytic leukemia; adult acute myeloid leukemia; ...
- Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002565 - Completed
Lymphoma
- Chemotherapy in Treating Children With Recurrent Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00003178 - Completed
Acute Myeloid Leukemia
- Amifostine and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00003268 - Completed
adult acute myeloid leukemia; Drug Toxicity
- Combination Chemotherapy in Treating Patients With Stage II or Stage III Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00006232 - Completed
stage II multiple myeloma; stage III multiple myeloma
- Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002812 - Completed
L2 childhood acute lymphoblastic leukemia; untreated childhood acute lymphoblastic leukemia; L1 childhood acute lymphoblastic leukemia
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002798 - Completed
Myeloid Leukemia; Refractory Anemia
- Phase II Study of Intensive Chemotherapy Followed by Autologous Peripheral Blood Stem Cell Transplantion in Patients With Chronic Myelogenous Leukemia or High Risk Acute Leukemia
ClinicalTrials.gov Identifier: NCT00004905 - Completed
adult acute myeloid leukemia in remission; chronic phase chronic myelogenous leukemia; recurrent adult acute myeloid leukemia; ...

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