Isoniazid |
INH; Nydrazid |
Image:Isoniazid.png Isoniazid Systematic (IUPAC) name pyridine-4-carbohydrazide Identifiers CAS number 54-85-3 ATC code J04AC01 PubChem 3767 DrugBank APRD01055 Chemical data Formula C6H7N3O Mol. weight 137.139 g/mol Pharmacokinetic data Bioavailability ? Protein binding Very low (0-10%) Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Isoniazid (also called i ...
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Isoniazid Clinical Trials
- A Study of the Effectiveness and Tolerability of Weekly Rifapentine/Isoniazid for Three Months Versus Daily Isoniazid for Nine Months for the Treatment of Latent Tuberculosis Infection
ClinicalTrials.gov Identifier: NCT00023452 - Recruiting
Tuberculosis
- Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Injection Drug Users
ClinicalTrials.gov Identifier: NCT00004740 - Active, not recruiting
Tuberculosis
- A Non-Comparative Study of the Efficacy of a Largely-Intermittent, Six-Month Tuberculosis Treatment Regimen Among Patients Who Will Not Receive Isoniazid Due to Initial Isoniazid Resistance or Intolerance
ClinicalTrials.gov Identifier: NCT00023374 - Active, not recruiting
Tuberculosis
- A Trial of Isoniazid for the Reversion of Interferon Gamma ELISPOT in TB Case Contacts
ClinicalTrials.gov Identifier: NCT00130325 - Recruiting
Tuberculosis
- Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers with HIV
ClinicalTrials.gov Identifier: NCT00080119 - Recruiting
HIV Infections; Tuberculosis; Pneumocystis carinii Pneumonia
- LTBI Rx in Jail
ClinicalTrials.gov Identifier: NCT00128206 - Active, not recruiting
Tuberculosis
- Isoniazid Prophylaxis With Concomitant Cotrimoxazole in HIV-Infected Children
ClinicalTrials.gov Identifier: NCT00330304 - Recruiting
Tuberculosis
- TBTC Study 28: Moxifloxacin Vs Isoniazid for TB Treatment
ClinicalTrials.gov Identifier: NCT00144417 - Active, not recruiting
Tuberculosis
- Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-Infected Persons in Botswana
ClinicalTrials.gov Identifier: NCT00164281 - Active, not recruiting
Tuberculosis; HIV Infections
- Treatment of Latent Tuberculosis Infection With Isoniazid
ClinicalTrials.gov Identifier: NCT00293228 - Recruiting
Tuberculosis
- Tuberculosis Prevention for HIV Infected Adults
ClinicalTrials.gov Identifier: NCT00057122 - Active, not recruiting
HIV Infections; Tuberculosis
- Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection
ClinicalTrials.gov Identifier: NCT00000636 - Active, not recruiting
HIV Infections; Tuberculosis
- Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Suspected Latent Tuberculous Infection
ClinicalTrials.gov Identifier: NCT00000959 - Active, not recruiting
HIV Infections; Tuberculosis
- Isoniazid Dose Adjustment According to NAT2 Genotype (IDANAT2)
ClinicalTrials.gov Identifier: NCT00571753 - Not yet recruiting
Pulmonary Tuberculosis
- A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin
ClinicalTrials.gov Identifier: NCT00000778 - Completed
HIV Infections; Tuberculosis
- TBTC Study 26 PK: Rifapentine Pharmacokinetics in Children During Treatment of Latent TB Infection
ClinicalTrials.gov Identifier: NCT00164450 - Recruiting
Tuberculosis
- Efficacy of Once-Weekly Rifapentine and Isoniazid in Treatment of Tuberculosis
ClinicalTrials.gov Identifier: NCT00023335 - Completed
Pulmonary Tuberculosis
- Pharmacokinetics of Intermittent Isoniazid
ClinicalTrials.gov Identifier: NCT00023348 - Completed
HIV Infections; Tuberculosis
- Isoniazid Plus HAART to Prevent TB in HIV-Infected Persons
ClinicalTrials.gov Identifier: NCT00463086 - Not yet recruiting
Tuberculosis; Mycobacterial Diseases; HIV Infections
- Short-Course Isoniazid and Rifampin Compared With Isoniazid for Latent Tuberculosis Infection
ClinicalTrials.gov Identifier: NCT00397709 - Terminated
Tuberculosis
- Kidney Transplants in People with HIV Infection
ClinicalTrials.gov Identifier: NCT00023478 - Active, not recruiting
HIV Infections; End-Stage Renal Disease
- Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients with HIV-Related Tuberculosis Treated with a Rifabutin-Based Regimen
ClinicalTrials.gov Identifier: NCT00018083 - Recruiting
Tuberculosis; HIV Infections
- Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-Infected Adults (ANRS 12136 TEMPRANO)
ClinicalTrials.gov Identifier: NCT00495651 - Not yet recruiting
HIV Infections; Tuberculosis
- TBTC Study 27: Moxifloxacin Vs Ethambutol for TB Treatment
ClinicalTrials.gov Identifier: NCT00140309 - Completed
Tuberculosis, Pulmonary
- High-Dose Isoniazid Adjuvant Therapy for Multidrug Resistant Tuberculosis
ClinicalTrials.gov Identifier: NCT00513396 - Completed
Tuberculosis, Multidrug-Resistant
- Treatment Shortening Trial
ClinicalTrials.gov Identifier: NCT00130247 - Suspended
Tuberculosis
- Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients with Tuberculosis
ClinicalTrials.gov Identifier: NCT00004736 - Completed
HIV Infections; Tuberculosis
- Preventive Treatment Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection
ClinicalTrials.gov Identifier: NCT00000638 - Completed
HIV Infections; Tuberculosis
- The Treatment of Tuberculosis in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001033 - Completed
HIV Infections; Tuberculosis
- Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis
ClinicalTrials.gov Identifier: NCT00000950 - Completed
HIV Infections; Tuberculosis
- Pharmacokinetics of Intermittent Rifabutin and Isoniazid with Daily Efavirenz
ClinicalTrials.gov Identifier: NCT00023413 - Completed
HIV Infections; Tuberculosis
- Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-desacetyl Rifapentine
ClinicalTrials.gov Identifier: NCT00023387 - Completed
Tuberculosis
- A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in
ClinicalTrials.gov Identifier: NCT00000796 - Completed
HIV Infections; Tuberculosis

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