Nitric Oxide Clinical Trials

• Follow Up at School-Age of Children Who Participated in the Efficacy Study of Nitric Oxide for Premature Infants
  ClinicalTrials.gov Identifier: NCT00152542 - Active, not recruiting
  Prematurity, Respiratory distress syndrome,Hypoxemia
  
• The Effects of Nitric Oxide for Inhalation During Left Ventricular Assists Device (LVAD) Implantation
  ClinicalTrials.gov Identifier: NCT00060840 - Recruiting
  Congestive Heart Failure
  
• Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises
  ClinicalTrials.gov Identifier: NCT00094887 - Recruiting
  Anemia, Sickle Cell
  
• Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis
  ClinicalTrials.gov Identifier: NCT00142051 - Recruiting
  Sickle Cell Disease
  
• Inhaled Nitric Oxide and Transfusion Therapy for Patients with Sickle Cell Anemia and Secondary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00023296 - Active, not recruiting
  Sickle Cell Anemia; Pulmonary Hypertension
  
• NO Need to Ventilate: A Trial of Non-Invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn
  ClinicalTrials.gov Identifier: NCT00139217 - Recruiting
  Pulmonary Hypertension
  
• Study of Inhaled Nitric Oxide for Preterm Infants
  ClinicalTrials.gov Identifier: NCT00016523 - Active, not recruiting
  Respiratory Distress Syndrome; Infant, Premature; Sepsis; Pneumonia; Hypertension, Pulmonary
  
• Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange
  ClinicalTrials.gov Identifier: NCT00568347 - Active, not recruiting
  COPD
  
• Evaluation of Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange
  ClinicalTrials.gov Identifier: NCT00569348 - Active, not recruiting
  COPD
  
• Nitric Oxide Administration for Acute Respiratory Distress Syndrome
  ClinicalTrials.gov Identifier: NCT00240487 - Recruiting
  ARDS
  
• Effect of Budesonide on Exhaled Nitric Oxide in Asthmatic Children
  ClinicalTrials.gov Identifier: NCT00522782 - Recruiting
  Asthma
  
• Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma
  ClinicalTrials.gov Identifier: NCT00395096 - Active, not recruiting
  Asthma
  
• Possible Relation of Toll-Like Receptors and Nitric Oxide to Chronic Lung Disease
  ClinicalTrials.gov Identifier: NCT00245167 - Active, not recruiting
  Lung Diseases
  
• Inhaled Nitric Oxide in Neonates with Elevated A-a DO2 Gradients Not Requiring Mechanical Ventilation
  ClinicalTrials.gov Identifier: NCT00041548 - Completed
  Lung Disease; Hypoxemia; Respiratory Acidosis
  
• Nitric Oxide Inhalation Therapy to Relieve Chest Pain in Patients with Coronary Artery Disease
  ClinicalTrials.gov Identifier: NCT00014040 - Completed
  Coronary Disease; Myocardial Ischemia
  
• Prolonged Outcomes After Nitric Oxide (PrONOx)
  ClinicalTrials.gov Identifier: NCT00234247 - Active, not recruiting
  Lung Diseases; Bronchopulmonary Dysplasia; Infant, Premature; Developmental Disabilities; Developmental Delay Disorders
  
• Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in Adolescents
  ClinicalTrials.gov Identifier: NCT00114413 - Active, not recruiting
  Asthma
  
• Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants
  ClinicalTrials.gov Identifier: NCT00308633 - Recruiting
  Coronary Artery Disease (CAD)
  
• Effects of Nitrite on Blood Vessel Dilation in Normal Volunteers
  ClinicalTrials.gov Identifier: NCT00048477 - Completed
  Nitric Oxide; Endothelium-Derived Relaxing Factor; Healthy
  
• Study of Arginine Metabolism and Nitric Oxide Formation in Relation to Glutamine Supply in Severely Burned Patients.
  ClinicalTrials.gov Identifier: NCT00216970 - Recruiting
  Burn Injury
  
• Inhaled Nitric Oxide in Prevention/Treatment of Ischemia-Reperfusion Lung Injury Related to Lung Transplantation
  ClinicalTrials.gov Identifier: NCT00060450 - Completed
  Ischemia-Reperfusion Injury
  
• Nitric Oxide and the Autonomic Nervous System
  ClinicalTrials.gov Identifier: NCT00178919 - Recruiting
  Hypertension; Pure Autonomic Failure
  
• Assessment of Utility of Exhaled Nitric Oxide Measurement for Treatment Monitoring in Children With Asthma
  ClinicalTrials.gov Identifier: NCT00500253 - Recruiting
  Asthma
  
• Role of Nitric Oxide in Malaria
  ClinicalTrials.gov Identifier: NCT00527163 - Recruiting
  Malaria; Pulmonary Hypertension
  
• Monitoring Asthma Treatment Using Exhaled Nitric Oxide
  ClinicalTrials.gov Identifier: NCT00562991 - Recruiting
  Asthma
  
• Effects of Inhaled Nitric Oxide in the Treatment of Acute Hypoxemic Respiratory Failure (AHRF) in Pediatrics
  ClinicalTrials.gov Identifier: NCT00041561 - Terminated
  Respiratory Insufficiency; Anoxemia
  
• Inhaled Nitric Oxide and Neuroprotection in Premature Infants
  ClinicalTrials.gov Identifier: NCT00515281 - Not yet recruiting
  Prematurity; Bronchopulmonary Dysplasia; Intraventricular Hemorrhage; Periventricular Leukomalacia
  
• Controlled Nitric Oxide Releasing Patch Versus Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis
  ClinicalTrials.gov Identifier: NCT00317629 - Recruiting
  Cutaneous Leishmaniasis
  
• Clinical Trial for the Treatment of Diabetic Foot Ulcers Using a Nitric Oxide Releasing Patch: PATHON
  ClinicalTrials.gov Identifier: NCT00428727 - Recruiting
  Diabetic Foot
  
• Pilot Study of Inhaled Nitric Oxide to Treat Pulmonary Insufficiency in Congenital Heart Disease
  ClinicalTrials.gov Identifier: NCT00543933 - Recruiting
  Pulmonary Insufficiency
  
• Safety and Efficacy Study of Nitric Oxide for Inhalation on Chronic Lung Disease in Premature Babies
  ClinicalTrials.gov Identifier: NCT00551642 - Recruiting
  Lung Disease
  
• The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)
  ClinicalTrials.gov Identifier: NCT00346970 - Recruiting
  Metabolic Syndrome
  
• Nitric Oxide in Myocardial Infarction Size
  ClinicalTrials.gov Identifier: NCT00568061 - Recruiting
  Acute Myocardial Infarction; ST Elevation MI; STEMI
  
• Safety and Efficacy Study of Nitric Oxide in Patients Going Through Lung Transplantation
  ClinicalTrials.gov Identifier: NCT00570245 - Recruiting
  Lung Transplantation
  
• Safety and Tolerability of Inhaled Nitric Oxide in Patients With Cystic Fibrosis
  ClinicalTrials.gov Identifier: NCT00570349 - Recruiting
  Cystic Fibrosis
  
• The Use of Exhaled Nitric Oxide in Conjunction With the Asthma Control Test to Determine Asthma Control in Pediatric Patients
  ClinicalTrials.gov Identifier: NCT00575445 - Recruiting
  Asthma
  
• Iloprost-Study: Comparison of Nitric Oxide to Iloprost (Ventavis) for Treatment of Pulmonary Hypertension in Children After Cardiopulmonary Bypass Surgery
  ClinicalTrials.gov Identifier: NCT00235521 - Recruiting
  Pulmonary Hypertension
  
• Alpha-Adrenoceptor Vascular Function In Chronic Kidney Disease Focus On The Role Of Endothelial Nitric Oxide
  ClinicalTrials.gov Identifier: NCT00356265 - Recruiting
  Chronic Kidney Disease; Hypertension
  
• Inhaled Nitric Oxide in Pulmonary Embolism
  ClinicalTrials.gov Identifier: NCT00565253 - Recruiting
  Pulmonary Embolism
  
• Role of nitric oxide in cirrhosis: relationship with systemic hemodynamics, renal function, vasoactive systems and endotoxemia
  ClinicalTrials.gov Identifier: NCT00005107 - Recruiting
  Cirrhosis; Liver Cirrhosis
  
• Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers
  ClinicalTrials.gov Identifier: NCT00545298 - Recruiting
  Venous Stasis Ulcers
  
• Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide
  ClinicalTrials.gov Identifier: NCT00569530 - Not yet recruiting
  Surfactant Dysfunction; Bronchopulmonary Dysplasia
  
• Zileuton and Exhaled Nitric Oxide in Asthmatics
  ClinicalTrials.gov Identifier: NCT00575861 - Completed
  Asthma
  
• Role of Endothelin- and Nitric Oxide-System in the Regulation of Optic Nerve Head Blood Flow During Changes in Ocular Perfusion Pressure
  ClinicalTrials.gov Identifier: NCT00406731 - Recruiting
  Ocular Physiology; Optic Disk; Regional Blood Flow
  
• Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After Transplantation
  ClinicalTrials.gov Identifier: NCT00582010 - Not yet recruiting
  Reperfusion Injury; Liver Injury
  
• Effects of Endotoxin in Normal Human Volunteers
  ClinicalTrials.gov Identifier: NCT00001303 - Active, not recruiting
  Healthy; Lung Disease; Sepsis; Septic Shock
  
• Biomarkers of iNOS Activity in COPD, Asthma, Healthy Control
  ClinicalTrials.gov Identifier: NCT00159302 - Completed
  Healthy smokers; Healthy non-smokers; Patients with mild asthma; Patints with COPD (GOLD II)
  
• NORDIC: Improving Nitric Oxide-Derived Oxidants Using Rosiglitazone in Non-Diabetic Dilated Cardiomyopathy
  ClinicalTrials.gov Identifier: NCT00293137 - Not yet recruiting
  Chronic Systolic Heart Failure (Dilated Cardiomyopathy)
  
• Effects of Growth Hormone on the Nitric Oxide Pathway
  ClinicalTrials.gov Identifier: NCT00470002 - Completed
  Cardiovascular Disease
  
• Dietary Nitrate and Nitrite to Increase Nitric Oxide in Patients with Coronary Artery Disease
  ClinicalTrials.gov Identifier: NCT00069654 - Recruiting
  Coronary Arteriosclerosis
  
• Pilot Study On The Role Of Nitric Oxide In Alpha 1-Adrenergic Vasoreactivity
  ClinicalTrials.gov Identifier: NCT00240058 - Completed
  Blood Pressure
  
• Early Inhaled Nitric Oxide for Respiratory Failure in Newborns
  ClinicalTrials.gov Identifier: NCT00005773 - Completed
  Hypertension, Pulmonary; Respiratory Insufficiency; Infant, Newborn, Diseases; Meconium Aspiration; Persistent Fetal Circulation Syndrome; ...
  
• STUDIES OF ACUTE LUNG INJURY (ALI) AND ACUTE RESPIRATORY DISTRESS SYNDROME
  ClinicalTrials.gov Identifier: NCT00159510 - Recruiting
  septic shock, acute lung injury
  
• Effect of Nitric Oxide Donor on Endothelial Progenitor Cells in Patients with Coronary Artery Disease
  ClinicalTrials.gov Identifier: NCT00090558 - Completed
  
  
• Development of a Hospital-Based Home Program for the Use of Inhaled Nitric Oxide in the Chronic Management of Severe Cardiopulmonary Diseases
  ClinicalTrials.gov Identifier: NCT00041574 - Terminated
  Pulmonary Hypertension; Lung Disease; Sickle Cell Disease; Cardiac transplant; Lung transplant
  
• ENIGMA - Evaluation of Nitrous Oxide In the Gas Mixture for Anaesthesia: a Randomised Controlled Trial
  ClinicalTrials.gov Identifier: NCT00164047 - Recruiting
  Quality of Recovery From Anaesthesia; Effects of Nitrous Oxide Following Anaesthesia; Induced Endothelial Dysfunction
  
• Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets
  ClinicalTrials.gov Identifier: NCT00027157 - Completed
  Healthy
  
• Sleep Apnea and Oxidative Stress and Nitric Oxide
  ClinicalTrials.gov Identifier: NCT00547937 - Completed
  Sleep Apnea Syndromes
  
• Nitric Oxide-Releasing Acetylsalicyclic Acid in Preventing Colorectal Cancer in Patients at High Risk of Colorectal Cancer
  ClinicalTrials.gov Identifier: NCT00331786 - Completed
  Colorectal Cancer
  
• Inhaled Nitric Oxide Study for Respiratory Failure in Newborns.
  ClinicalTrials.gov Identifier: NCT00005776 - Terminated
  Hypertension, Pulmonary; Respiratory Insufficiency; Infant, Newborn, Diseases; Meconium Aspiration; Persistent Fetal Circulation Syndrome; ...
  
• Nitric Oxide to Improve Blood Flow in Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00009581 - Completed
  Sickle Cell Anemia
  
• Nitric Oxide, Endothelin-1, and the Patency of Ductus Arteriosus in Preterm Infants
  ClinicalTrials.gov Identifier: NCT00162903 - Completed
  Patent Ductus Arteriosus
  
• Vascular Effects of Endothelium-Derived Versus Hemoglobin-Transported Nitric Oxide in Healthy Subjects
  ClinicalTrials.gov Identifier: NCT00001963 - Completed
  Diabetes Mellitus; Healthy; Hypercholesterolemia; Hypertension
  
• Nitrous Oxide for Analgesia During Colonoscopy
  ClinicalTrials.gov Identifier: NCT00318825 - Recruiting
  Pain
  
• 50% Nitrous Oxide and 50% Oxygen (MEOPA) Conscious Sedation Versus Placebo in Fiberoptic Bronchoscopy
  ClinicalTrials.gov Identifier: NCT00392522 - Active, not recruiting
  Fiberoptic Bronchoscopy
  
• Effects of Nitric Oxide and Nitroglycerin in Patients with Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00001716 - Completed
  Chest Pain; Sickle Cell Anemia
  
• Titanium Nitride Oxide Coated Stents and Paclitaxel Eluting Stents for Acute Myocardial Infarction
  ClinicalTrials.gov Identifier: NCT00495664 - Active, not recruiting
  Acute Myocardial Infarction
  
• Effect of Nitrous Oxide on Intravenous Closed-Loop Anesthesia
  ClinicalTrials.gov Identifier: NCT00547209 - Recruiting
  General Anesthesia
  
• Allergy Towards Grass and Bronchial Inflammation - Related to Immunotherapy and Exhaled Nitrogen Oxide
  ClinicalTrials.gov Identifier: NCT00312312 - Recruiting
  Asthma, Bronchial; Allergic Rhinitis; Hypersensitivity, Immediate
  
• Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly
  ClinicalTrials.gov Identifier: NCT00212147 - Recruiting
  Avitaminosis; Delirium, Dementia, Amnestic, Cognitive Disorders
  
• A Study of the Safety and Efficacy of Nitric Oxide Reduction in Patients with Cardiogenic Shock After a Heart Attack
  ClinicalTrials.gov Identifier: NCT00112281 - Terminated
  Shock, Cardiogenic
  
• Combidex USPIO - Ultra-Small Superparamagnetic Iron Oxide
  ClinicalTrials.gov Identifier: NCT00188695 - Recruiting
  Uterine Neoplasms; Cervix Neoplasms; Bladder Neoplasms; Prostatic Neoplasms
  
• Homocysteine After Nitrous Oxide Anesthesia
  ClinicalTrials.gov Identifier: NCT00482456 - Completed
  Anesthesia, General; Adverse Effects; Nitrous Oxide
  
• The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial
  ClinicalTrials.gov Identifier: NCT00430989 - Not yet recruiting
  Coronary Artery Disease
  
• Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16
  ClinicalTrials.gov Identifier: NCT00000264 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2
  ClinicalTrials.gov Identifier: NCT00000250 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7
  ClinicalTrials.gov Identifier: NCT00000255 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Effects of Combined Alcohol and Nitrous Oxide Intake - 15
  ClinicalTrials.gov Identifier: NCT00000263 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14
  ClinicalTrials.gov Identifier: NCT00000262 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4
  ClinicalTrials.gov Identifier: NCT00000252 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Role of Instructions in Nitrous Oxide Effects and Choice - 10
  ClinicalTrials.gov Identifier: NCT00000258 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Subjective Effects of Nitrous Oxide in Dental Patients - 17
  ClinicalTrials.gov Identifier: NCT00000265 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Preprocedural Fasting and Nitrous Oxide -Oxygen Inhalation Analgesia for Dental Treatment of Children
  ClinicalTrials.gov Identifier: NCT00263289 - Not yet recruiting
  Vomiting
  
• Effects of Nitrous Oxide: A Dose-Response Analysis - 5
  ClinicalTrials.gov Identifier: NCT00000253 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3
  ClinicalTrials.gov Identifier: NCT00000251 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Effects of Subanesthetic Concentrations of Nitrous Oxide - 1
  ClinicalTrials.gov Identifier: NCT00000249 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8
  ClinicalTrials.gov Identifier: NCT00000256 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Analysis of Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium
  ClinicalTrials.gov Identifier: NCT00253006 - Terminated
  Painful Bladder Syndrome; Interstitial Cystitis; Bladder Disease; Incontinence
  
• Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12
  ClinicalTrials.gov Identifier: NCT00000260 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13
  ClinicalTrials.gov Identifier: NCT00000261 - Completed
  Alcohol-Related Disorders; Opioid-Related Disorders; Substance-Related Disorders
  
• Effects of Alcohol History on Effects of Nitrous Oxide - 9
  ClinicalTrials.gov Identifier: NCT00000257 - Completed
  Alcohol-Related Disorders; Opioid-Related Disorders; Substance-Related Disorders
  
• Intraoperative Nitrous Oxide and Postoperative Pain for Patients With Current Opioid Treatment
  ClinicalTrials.gov Identifier: NCT00210158 - Completed
  Chronic Pain
  
• Clinical Performance of Extended All-Ceramic Fixed Partial Dentures Based on Zircon-Oxide Ceramics.
  ClinicalTrials.gov Identifier: NCT00176189 - Completed
  Tooth Loss, Teeth Replaced Using All Ceramic FPDs
  
• Quantifying Nitrous Oxide Effect on Depth of Anaesthesia Using Theoretically Based Time Series Modelling
  ClinicalTrials.gov Identifier: NCT00226837 - Completed
  Depth of Anaesthesia
  
• The Effect of N2O Administration on Arterial Oxygenation
  ClinicalTrials.gov Identifier: NCT00146250 - Completed
  Pulmonary function under anaesthesia.
  
• Sevoflurane vs Isoflurane Inhalation at Subanesthetic Concentrations - 11
  ClinicalTrials.gov Identifier: NCT00000259 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Isoflurane at Subanesthetic Concentrations - 6
  ClinicalTrials.gov Identifier: NCT00000254 - Completed
  Opioid-Related Disorders; Substance-Related Disorders
  
• Evaluation of Pain Intensity During Bone Marrow Biopsy Performed With Inhalation of Pre-Mixed 50 Per Cent Nitrous Oxide and Oxygen Mixture.
  ClinicalTrials.gov Identifier: NCT00219713 - Terminated
  Pain