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Interferon Beta-1a Injection (Rebif |
Rebif |
Image:Interferon beta-1a.png Interferon beta-1a Systematic (IUPAC) name Human interferon beta Identifiers CAS number 145258-61-3 ATC code L03AB07 PubChem ? DrugBank BTD00093 Chemical data Formula C908H1408N246O252S7 Mol. weight 20027.0 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life 10 hrs Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Interferon beta-1a is a drug ...
Wikipedia - [full article]
Interferon Beta-1a Injection (Rebif Clinical Trials
- Safety Study of Interferon Beta 1a to for Acute Stroke
ClinicalTrials.gov Identifier: NCT00097318 - Active, not recruiting
Cerebrovascular Accident
- Safety and Tolerability of Interferon-Beta-1a and Estroprogestins Association in MS Patients
ClinicalTrials.gov Identifier: NCT00151801 - Recruiting
Multiple Sclerosis
- Rebif® New Formulation in Relapsing Forms of Multiple Sclerosis (RMS)
ClinicalTrials.gov Identifier: NCT00110396 - Active, not recruiting
Multiple Sclerosis
- Minocycline as Add-on to Interferon-Beta-1a (Rebif®) in RRMS (Recycline)
ClinicalTrials.gov Identifier: NCT00381459 - Recruiting
Relapsing-Remitting Multiple Sclerosis
- Rebif® versus Copaxone® in the Treatment of Relapsing Remitting Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00078338 - Completed
Relapsing-Remitting Multiple Sclerosis
- Avonex (Interferon-Beta-1a) and Avonex Plus Methylprednisolone for the Treatment of Relapsing-Remitting MS
ClinicalTrials.gov Identifier: NCT00168766 - Active, not recruiting
Relapsing-Remitting Multiple Sclerosis
- Combination Therapy with Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00037102 - Active, not recruiting
Multiple Sclerosis
- Simvastatin as an Add-on Treatment to Interferon-Beta-1a for the Treatment of Relapsing-Remitting Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00492765 - Recruiting
Multiple Sclerosis
- Effect of Interferon Beta-1a (Avonex®) on Changes of Non-Conventional MRI Measures in Patients With MS
ClinicalTrials.gov Identifier: NCT00463710 - Completed
Multiple Sclerosis
- Is IFN-Beta Treatment in MS Useful After a Washout Period in Patients With Neutralizing Antibodies to Interferon Beta
ClinicalTrials.gov Identifier: NCT00493116 - Active, not recruiting
Relapsing-Remitting Multiple Sclerosis
- A Multicentre Phase III Study of Interferon-Beta-1a for the Treatment of Chronic Hepatitis C in Asian Patients
ClinicalTrials.gov Identifier: NCT00249860 - Completed
Hepatitis C
- EARLY IFNb-1a and Atorvastatin Combination Therapy of Isolated Clinical Syndrome Suggestive of Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00137176 - Recruiting
Multiple Sclerosis
- Safety and Efficacy of Interferon Beta-1a Rebif® for Treating Patients With Acute Symptoms of Ulcerative Colitis
ClinicalTrials.gov Identifier: NCT00303381 - Completed
Ulcerative Colitis
- Does Quality of Life Improve in Multiple Sclerosis Patients Treated With Interferon Beta-1a?
ClinicalTrials.gov Identifier: NCT00534261 - Completed
Relapsing Remitting Multiple Sclerosis
- Interferon-beta Treatment of Ulcerative Colitis
ClinicalTrials.gov Identifier: NCT00048347 - Recruiting
Ulcerative Colitis
- Safety and Efficacy Study of Doxycycline in Combination With Interferon-B-1a to Treat Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00246324 - Active, not recruiting
Multiple Sclerosis
- Investigating if Interferon-Beta Can be Used in Patients With MS After They Have Developed Neutralizing Antibodies
ClinicalTrials.gov Identifier: NCT00492466 - Active, not recruiting
Relapsing-Remitting Multiple Sclerosis
- Induction Therapy with a Single High Dose Bolus of Intravenous Methotrexate with Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting with a First Acute Demyelinating Event.
ClinicalTrials.gov Identifier: NCT00037115 - Not yet recruiting
Demyelinating Disorders; Multiple Sclerosis; Optic Neuritis; Myelitis; Neuritis
- Safety and Efficacy of Treatment With Interferon Beta-1a Rebif® in Patients With Crohn’s Disease
ClinicalTrials.gov Identifier: NCT00304252 - Terminated
Crohn’s Disease
- Gene Expression in MS Patients Before and During Treatment With Interferon-Beta
ClinicalTrials.gov Identifier: NCT00202384 - Recruiting
Multiple Sclerosis
- A Study to Evaluate Rebif® New Formulation (IFN-Beta-1a) in Relapsing Remitting Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00441103 - Recruiting
Multiple Sclerosis, Relapsing-Remitting
- Randomized Study of Beta Interferon and Thalidomide in Patients with Adrenoleukodystrophy
ClinicalTrials.gov Identifier: NCT00004450 - Completed
Adrenoleukodystrophy
- Open Label Phase I Study To Evaluate the Safety of Combination Therapy With AZT and Interferon-Beta in Patients With AIDS Related Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00000695 - Completed
Sarcoma, Kaposi; HIV Infections
- The Safety and Effectiveness of Ganciclovir Plus Interferon Beta in Preventing the Return of Cytomegalovirus (CMV) of the Eyes in Patients with AIDS
ClinicalTrials.gov Identifier: NCT00002299 - Completed
Cytomegalovirus Retinitis; HIV Infections
- BEYOND Study - Betaferon/Betaseron Efficacy Yielding Outcomes of a New Dose in Multiple Sclerosis (MS) Patients
ClinicalTrials.gov Identifier: NCT00099502 - Active, not recruiting
Multiple Sclerosis
- Recombinant Human Interferon Beta-1a (Avonex) for the Treatment of Patients with HTLV-1-Associated Myelopathy (HAM)
ClinicalTrials.gov Identifier: NCT00001785 - Completed
HTLV-I Infection; Spinal Cord Disease; Tropical Spastic Paraparesis
- Rebif New Formulation (RNF) Quality of Life Study
ClinicalTrials.gov Identifier: NCT00472797 - Active, not recruiting
Relapsing Multiple Sclerosis
- Safety of Avonex Treatment in Multiple Sclerosis Patients With Neutralizing Antibodies to Interferon Beta Therapy
ClinicalTrials.gov Identifier: NCT00493077 - Recruiting
Multiple Sclerosis
- Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis
ClinicalTrials.gov Identifier: NCT00344253 - Recruiting
Uveitis, Intermediate; Macular Edema; Multiple Sclerosis
- Thymosin Plus PEG-Interferon in Hepatitis C Patients with Cirrhosis Who Did Not Respond to Interferon or Interferon Plus Ribavirin
ClinicalTrials.gov Identifier: NCT00039962 - Active, not recruiting
Hepatitis C; Hepatitis C, Chronic
- Interferon Alfa in Treating Children With HIV-Related Cancer
ClinicalTrials.gov Identifier: NCT00002621 - Active, not recruiting
Leukemia; Lymphoma
- Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug Users
ClinicalTrials.gov Identifier: NCT00194480 - Recruiting
Substance-Related Disorders; Hepatitis
- Safety and Efficacy of Avonex in Subjects with Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
ClinicalTrials.gov Identifier: NCT00099489 - Completed
Chronic Inflammatory Demyelinating Polyradiculoneuropathy; Guillain-Barre Syndrome
- Extension Study on Efficacy and Safety of Deferasirox Treatment in Patients With Beta-Thalassemia and Transfusional Hemosiderosis
ClinicalTrials.gov Identifier: NCT00171301 - Active, not recruiting
Beta-Thalassemia Major
- REbif FLEXible Dosing in Early MS
ClinicalTrials.gov Identifier: NCT00404352 - Recruiting
Multiple Sclerosis
- Genetic Factors Affecting the Severity of Beta Thalassemia
ClinicalTrials.gov Identifier: NCT00159042 - Recruiting
beta Thalassemia
- Thymosin Plus PEG-Interferon in Non-Cirrhotic Hepatitis C Patients Who Did Not Respond to Interferon or Interferon Plus Ribavirin
ClinicalTrials.gov Identifier: NCT00040027 - Active, not recruiting
Hepatitis C; Hepatitis C, Chronic
- Study of Protein Translocation in Patients With Beta-Oxidation Disorders
ClinicalTrials.gov Identifier: NCT00004348 - Active, not recruiting
Beta-Oxidation Disorder; Peroxisomal Disorders
- Beta-Blocker Continuation Versus Interruption in Heart Failure Worsening
ClinicalTrials.gov Identifier: NCT00162565 - Recruiting
Heart Failure,Congestive; beta-Adrenergic Blockers
- Insulin Glargine (Lantus) vs Sulfonylurea (SU) for BETA Cell Function (BETA Study)
ClinicalTrials.gov Identifier: NCT00562172 - Recruiting
Type 2 Diabetes Mellitus
- Standard High-Dose Alpha Interferon Versus Intermittent High-Dose Alpha Interferon
ClinicalTrials.gov Identifier: NCT00226408 - Recruiting
Adjuvant; Stage III Malignant Melanoma; Interferon Alpha; Therapy
- Interferon alfa in Treating Patients With Recurrent Unresectable Meningiomas and Malignant Meningiomas
ClinicalTrials.gov Identifier: NCT00002965 - Active, not recruiting
recurrent adult brain tumor
- Interferon beta in Treating Patients With Metastatic Cutaneous Melanoma or Ocular Melanoma
ClinicalTrials.gov Identifier: NCT00085306 - Completed
Recurrent Melanoma; Stage IV Melanoma; iris melanoma; ciliary body and choroid melanoma, medium/large size; extraocular extension melanoma; ...
- Interferon alfa Following Surgery in Treating Patients With Stage III Melanoma
ClinicalTrials.gov Identifier: NCT00006249 - Active, not recruiting
stage III melanoma
- Combination Chemotherapy With or Without Interleukin-2 and Interferon alfa in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00003027 - Active, not recruiting
Stage IV Melanoma
- Combined Chelation Treatment with Deferiprone and Deferoxamine in Thalassemia Major
ClinicalTrials.gov Identifier: NCT00103753 - Active, not recruiting
beta-Thalassemia
- Dexamethasone Plus Interferon alfa in Treating Patients With Primary Systemic Amyloidosis
ClinicalTrials.gov Identifier: NCT00002849 - Active, not recruiting
primary systemic amyloidosis
- Phase II Cladribine Add-on to Rebif New Formulation in MS Subjects With Active Disease (ONWARD)
ClinicalTrials.gov Identifier: NCT00436826 - Recruiting
Multiple Sclerosis
- TLK286 (Telcyta) vs. Doxil/Caelyx or Hycamtin in Platinum Refractory or Resistant Ovarian Cancer
ClinicalTrials.gov Identifier: NCT00057720 - Active, not recruiting
Ovarian Neoplasms
- Interferon alfa With or Without Combination Chemotherapy Plus Interleukin-2 in Treating Patients With Melanoma
ClinicalTrials.gov Identifier: NCT00002882 - Active, not recruiting
stage III melanoma
- Combination Chemotherapy, Interferon alfa, and Interleukin-2 in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00002669 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma
- Interferon alfa With or Without Interleukin-2 and Fluorouracil in Treating Patients With Advanced Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00053820 - Active, not recruiting
Stage IV Renal Cell Cancer
- Serotonin 1A Agonists and Cognition in Schizophrenia
ClinicalTrials.gov Identifier: NCT00178971 - Active, not recruiting
Schizophrenia; Schizoaffective Disorder
- Cardiac T2* in Beta-Thalassemia Patients on Deferasirox Treatment
ClinicalTrials.gov Identifier: NCT00447694 - Recruiting
Beta-Thalassemia; Iron Overload
- Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major
ClinicalTrials.gov Identifier: NCT00336362 - Recruiting
Beta-Thalassemia
- PEG-Interferon alfa-2b in Treating Patients With Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00045279 - Active, not recruiting
Stage IV Renal Cell Cancer
- Safety and antiviral study of ACH-126, 443 (beta-L-Fd4C) in the treatment of adults with HIV infection and modestly detectable viral load.
ClinicalTrials.gov Identifier: NCT00040157 - Active, not recruiting
HIV Infections
- Beta Alethine in Treating Patients With Low-Grade Lymphoma
ClinicalTrials.gov Identifier: NCT00007839 - Active, not recruiting
Lymphoma
- Paroxetine for the Treatment of Interferon Related Side Effects for Hepatitis C
ClinicalTrials.gov Identifier: NCT00209118 - Active, not recruiting
Hepatitis C; Depression; Interferon-Alpha Associated Side Effects
- Interleukin-12 and Interferon alfa in Treating Patients With Metastatic Malignant Melanoma
ClinicalTrials.gov Identifier: NCT00026143 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma
- Combination Chemotherapy Plus Interferon alfa or Rituximab in Treating Patients With Stage III or Stage IV Lymphoma
ClinicalTrials.gov Identifier: NCT00004039 - Active, not recruiting
Lymphoma
- Reduction of Immunosuppression Plus Interferon alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant
ClinicalTrials.gov Identifier: NCT00002657 - Active, not recruiting
Lymphoma; Multiple Myeloma
- Tretinoin Plus Interferon alfa in Treating Patients With Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00003656 - Active, not recruiting
Stage IV Renal Cell Cancer; recurrent renal cell cancer
- Interferon alfa, Isotretinoin, and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00062010 - Active, not recruiting
Recurrent Small Cell Lung Cancer
- Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer
ClinicalTrials.gov Identifier: NCT00002504 - Active, not recruiting
Lymphoma; Leukemia
- Temozolomide plus PEG-Interferon alfa-2B in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00014261 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Efficacy of Pegylated Interferon On Liver Fibrosis in Co-Infected Patient with HIV and C Hepatitis Who Failed to Active Treatment for HCV
ClinicalTrials.gov Identifier: NCT00122616 - Active, not recruiting
HIV Infections; Hepatitis C, Chronic
- Combination Chemotherapy With or Without Interferon alfa in Treating Patients With Previously Untreated Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00002556 - Active, not recruiting
stage I multiple myeloma; stage II multiple myeloma; stage III multiple myeloma
- Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy
ClinicalTrials.gov Identifier: NCT00474838 - Recruiting
Type 2 Diabetes Mellitus; Pancreatic Beta Cell Function; Glucotoxicity
- Valopicitabine When Administered Alone and in Combination with Interferon to Treatment-Naive Patients with Hepatitis C
ClinicalTrials.gov Identifier: NCT00120835 - Active, not recruiting
Chronic Hepatitis C
- Beta Blockers Versus Variceal Band Ligation and Beta Blockers for Primary Prophylaxis of Variceal Bleeding
ClinicalTrials.gov Identifier: NCT00409084 - Recruiting
Esophageal Varices
- Randomized Trial of Beta-Carotene and Macular Degeneration
ClinicalTrials.gov Identifier: NCT00000152 - Active, not recruiting
Macular Degeneration
- A Safety and Efficacy Study of Prophylactically Administered Pegylated Interferon alfa-2a (Pegasys) plus Ribavirin vs. No Prophylaxis Following Liver Transplantation for Hepatitis C
ClinicalTrials.gov Identifier: NCT00087633 - Active, not recruiting
Hepatitis C
- PEG-Interferon alfa-2b, Sargramostim, and Thalidomide in Treating Patients With Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00090870 - Active, not recruiting
Stage IV Renal Cell Cancer
- Sorafenib With or Without Interferon Alfa-2b in Treating Patients With Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00126594 - Active, not recruiting
renal clear cell carcinoma; Stage IV Renal Cell Cancer
- Interferon alfa-2b in Treating Patients With Melanoma and Early Lymph Node Metastasis
ClinicalTrials.gov Identifier: NCT00004196 - Active, not recruiting
stage I melanoma; stage II melanoma; stage III melanoma
- Oblimersen and Interferon alfa in Treating Patients With Metastatic Renal Cell Cancer
ClinicalTrials.gov Identifier: NCT00059813 - Active, not recruiting
Stage IV Renal Cell Cancer; recurrent renal cell cancer
- Valopicitabine Alone and Together with Pegylated Interferon in Patients with Chronic Hepatitis C Who Have Failed to Respond to Standard Therapy
ClinicalTrials.gov Identifier: NCT00120861 - Active, not recruiting
Chronic Hepatitis C
- Betaferon®/ Betaseron® (Interferon Beta-1b) in Patients With Chronic Viral Cardiomyopathy
ClinicalTrials.gov Identifier: NCT00185250 - Completed
Cardiomyopathies; Heart Diseases
- Beta Alethine in Treating Patients With Waldenstrom's Macroglobulinemia
ClinicalTrials.gov Identifier: NCT00041379 - Active, not recruiting
Waldenstrom's Macroglobulinemia
- Interferon alfa and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00002847 - Active, not recruiting
Stage IV Renal Cell Cancer; recurrent renal cell cancer
- Safety and Tolerability of Pegylated Interferon (PEG-IFN) Alfa-2a in HIV Infected People
ClinicalTrials.gov Identifier: NCT00078442 - Active, not recruiting
HIV Infections
- Interferon alfa-2b With or Without Thalidomide in Treating Patients With Metastatic or Unresectable Kidney Cancer
ClinicalTrials.gov Identifier: NCT00005966 - Active, not recruiting
stage III renal cell cancer; Stage IV Renal Cell Cancer
- Comparison of Alemtuzumab and Rebif Efficacy in Multiple Sclerosis, Study One
ClinicalTrials.gov Identifier: NCT00530348 - Recruiting
Multiple Sclerosis, Relapsing-Remitting
- Comparison of Alemtuzumab and Rebif Efficacy in Multiple Sclerosis, Study Two
ClinicalTrials.gov Identifier: NCT00548405 - Recruiting
Multiple Sclerosis, Relapsing-Remitting
- Interleukin-2, Interferon alfa, and Fluorouracil Compared With Observation in Treating Patients Who Have Undergone Surgery for Kidney Cancer
ClinicalTrials.gov Identifier: NCT00053807 - Active, not recruiting
stage III renal cell cancer; Stage IV Renal Cell Cancer
- A Study to Evaluate the Combination of Pegylated Interferon Alfa Plus Valopicitabine in Patients with Hepatitis C
ClinicalTrials.gov Identifier: NCT00118768 - Active, not recruiting
Chronic Hepatitis C
- Vaccine Therapy Compared With Interferon alfa in Treating Patients With Stage III Melanoma
ClinicalTrials.gov Identifier: NCT00003715 - Active, not recruiting
stage III melanoma
- Isotretinoin, Interferon alfa, and Vitamin E in Treating Patients With Stage III or Stage IV Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00054561 - Active, not recruiting
Hypopharyngeal Cancer; Laryngeal Cancer; lip and oral cavity cancer; Oropharyngeal Cancer
- Interleukin-12 Followed by Interferon alfa in Treating Patients With Advanced Cancer
ClinicalTrials.gov Identifier: NCT00003451 - Active, not recruiting
Cancer
- PEDS-C: Pegylated Interferon +/- Ribavirin for Children with Hepatitis C
ClinicalTrials.gov Identifier: NCT00100659 - Active, not recruiting
Chronic Hepatitis C
- Adjuvant Chemoradiotherapy and Interferon alfa in Treating Patients With Resected Pancreatic Cancer
ClinicalTrials.gov Identifier: NCT00059826 - Active, not recruiting
stage I pancreatic cancer; stage II pancreatic cancer; stage III pancreatic cancer; adenocarcinoma of the pancreas
- Cisplatin, Interferon alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
ClinicalTrials.gov Identifier: NCT00003263 - Active, not recruiting
localized malignant mesothelioma
- Efficacy of Pegylated Interferon Alone in Egyptian Patients with Acute Hepatitis C (ANRS 1213)
ClinicalTrials.gov Identifier: NCT00158522 - Recruiting
Hepatitis C
- Interferon-Gamma With Interferon Alpha and Ribavirin for Hepatitis C Non-Responders
ClinicalTrials.gov Identifier: NCT00538811 - Recruiting
Hepatitis C; Genotype 3; Non-Responders; Relapsers
- Pegylated Interferon Therapy for Acute Hepatitis C Infection in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00132210 - Recruiting
Hepatitis C
- Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer
ClinicalTrials.gov Identifier: NCT00002475 - Active, not recruiting
Breast Cancer; Colorectal Cancer; kidney tumor; Lung Cancer; Pancreatic Cancer; pleura cancer
- SU011248 versus Interferon-alfa as First-Line Systemic Therapy for Patients with Metastatic Renal Cell Carcinoma
ClinicalTrials.gov Identifier: NCT00083889 - Active, not recruiting
Renal Cell Carcinoma
- Interferon-alfa With or Without Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002868 - Active, not recruiting
chronic phase chronic myelogenous leukemia
- Safety and antiviral study of ACH-126, 443 (beta-L-Fd4C) in the treatment of adults with chronic Hepatitis B infection.
ClinicalTrials.gov Identifier: NCT00037622 - Active, not recruiting
Chronic Hepatitis B
Resources
- Interferon Beta-1a Injection (Rebif(R)) (Drug Digest)
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