Lopinavir and Ritonavir Clinical Trials

• Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological Failure
  ClinicalTrials.gov Identifier: NCT00025727 - Active, not recruiting
  HIV Infections
  
• Differences in Blood Levels of Lopinavir/Ritonavir in HIV Infected Men and Women
  ClinicalTrials.gov Identifier: NCT00102986 - Active, not recruiting
  HIV Infections
  
• Safety and Effectiveness of Lopinavir/Ritonavir in HIV Infected Infants
  ClinicalTrials.gov Identifier: NCT00038480 - Active, not recruiting
  HIV Infections
  
• BLADE: Comparison of Once Daily Lopinavir/Ritonavir to Lopinavir/Ritonavir BID Dosing in HIV-Infected Subjects
  ClinicalTrials.gov Identifier: NCT00388492 - Not yet recruiting
  HIV Infections
  
• MEDICLAS Study (Metabolic Effects of Different Classes of AntiretroviralS)
  ClinicalTrials.gov Identifier: NCT00122226 - Active, not recruiting
  HIV Infections; HIV-Associated Lipodystrophy Syndrome
  
• A Study of the Contraceptive Patch and the Oral Contraceptive in HIV Infected Women Taking Lopinavir/Ritonavir
  ClinicalTrials.gov Identifier: NCT00125983 - Active, not recruiting
  HIV Infection; Contraception
  
• Safety of Saquinavir and High Doses of Lopinavir/Ritonavir in Children With HIV
  ClinicalTrials.gov Identifier: NCT00084058 - Active, not recruiting
  HIV Infections
  
• A Phase 3, Randomized, Open-Label, Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice-Daily Administration, When Co-Administered With NRTIs in Antiretroviral Naive HIV-1 Infected Subjects
  ClinicalTrials.gov Identifier: NCT00262522 - Active, not recruiting
  HIV Infection
  
• Safety of and Immune Response to Cyclosporine A in Combination with Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in Adults with Acute HIV Infection
  ClinicalTrials.gov Identifier: NCT00084149 - Active, not recruiting
  HIV Infections
  
• Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons with Drug Resistance
  ClinicalTrials.gov Identifier: NCT00046033 - Completed
  HIV Infections
  
• Anti-HIV Drugs During Pregnancy
  ClinicalTrials.gov Identifier: NCT00042289 - Active, not recruiting
  HIV Infections
  
• A Study of ABT-378/Ritonavir in HIV-Infected Patients
  ClinicalTrials.gov Identifier: NCT00004578 - Active, not recruiting
  HIV Infections
  
• RMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose Truvada
  ClinicalTrials.gov Identifier: NCT00272779 - Active, not recruiting
  HIV
  
• Induction Maintenance of Lopinavir/r in HIV-Infected Subjects
  ClinicalTrials.gov Identifier: NCT00159224 - Recruiting
  HIV-1 infection
  
• Pharmacokinetic and Efficacy of SQV/r 1500/100 Plus Tenofovir/Emtricitabine 300/200 mg
  ClinicalTrials.gov Identifier: NCT00476983 - Not yet recruiting
  Saquinavir/Ritonavir BID or Lopinavir/Ritonavir BID
  
• An Open Label, 3 Arms, Randomised Study To Compare The Efficacy And Safety Of Standard Dose Of Fosamprenavir/Ritonavir To 1) An Increased Dose Of Fosamprenavir (Doubled)/Ritonavir And 2) To Fosamprenavir (Double Dose)/Lopinavir/Ritonavir
  ClinicalTrials.gov Identifier: NCT00144833 - Terminated
  HIV-1 infection
  
• Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s)
  ClinicalTrials.gov Identifier: NCT00028301 - Completed
  HIV Infections
  
• Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIV
  ClinicalTrials.gov Identifier: NCT00027339 - Active, not recruiting
  HIV Infections
  
• Phase III Open Label Atazanavir (BMS-232632) in Combination with Ritonavir or Saquinavir, and Lopinavir/Ritonavir, each with Tenofovir and a Nucleoside in Subjects with HIV
  ClinicalTrials.gov Identifier: NCT00035932 - Active, not recruiting
  HIV Infections
  
• Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients
  ClinicalTrials.gov Identifier: NCT00028314 - Active, not recruiting
  HIV Infections; Lipodystrophy; Wasting Disease
  
• Pharmacokinetic Interactions Between Buprenorphine and Kaletra (Lopinavir/Ritonavir)
  ClinicalTrials.gov Identifier: NCT00571961 - Recruiting
  HIV Infections
  
• Drug Interaction Study of Lopinavir/Ritonavir and Gemfibrozil
  ClinicalTrials.gov Identifier: NCT00474201 - Recruiting
  HIV Infections; Cholesterol
  
• Abacavir/Lamivudine Versus Emtricitabine/Tenofovir Both In Combination With Lopinavir/Ritonavir For The Treatment Of HIV
  ClinicalTrials.gov Identifier: NCT00244712 - Active, not recruiting
  HIV Infections
  
• Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects
  ClinicalTrials.gov Identifier: NCT00043966 - Completed
  HIV Infections
  
• Safety of Lopinavir/Ritonavir (Kaletra) in HIV/HCV co-Infected Subjects vs Baseline Liver Biopsy Metavir Score
  ClinicalTrials.gov Identifier: NCT00234975 - Active, not recruiting
  HIV Infection
  
• Amprenavir/Ritonavir or Saquinavir/Ritonavir in HIV-Infected Patients Following Failure with Kaletra (lopinavir/ritonavir) as Their Second Protease Inhibitor.
  ClinicalTrials.gov Identifier: NCT00038519 - Completed
  HIV Infections
  
• A 48 week study looking at the effectiveness of giving saquinavir/ritonavir, twice daily plus emtricitabine/tenofovir, once daily compared to giving lopinavir/ritonavir twice daily plus emtricitabine/tenofovir once daily in HIV-1 patients not previously t
  ClinicalTrials.gov Identifier: NCT00105079 - Active, not recruiting
  HIV Infections
  
• Dual Versus Triple Protease Inhibitor Combinations, Including Ritonavir, in HIV Infected People
  ClinicalTrials.gov Identifier: NCT00028366 - Completed
  HIV Infections
  
• Drug Interactions of Echinacea, Ginseng, and Ginkgo Biloba Taken with Lopinavir/Ritonavir in Healthy Volunteers
  ClinicalTrials.gov Identifier: NCT00103012 - Recruiting
  
  
• A Study of Two Different Doses of ABT-378/Ritonavir in HIV-Infected Patients Who Have Taken Protease Inhibitors and Non-Nucleoside Reverse Transcriptase Inhibitors
  ClinicalTrials.gov Identifier: NCT00038636 - Completed
  HIV Infections
  
• Lopinavir/Ritonavir in Combination with Saquinavir Mesylate or Lamivudine/Zidovudine to Explore Metabolic Toxicities in Antiretroviral HIV-Infected Subjects
  ClinicalTrials.gov Identifier: NCT00043953 - Completed
  HIV Infections
  
• A Study of HIV-Disease Development in Aging
  ClinicalTrials.gov Identifier: NCT00006144 - Active, not recruiting
  HIV Infections
  
• Comparative Pharmacokinetics (PK) Study of Efavirenz or Lopinavir/Ritonavir Between Older and Younger HIV-Infected Adults
  ClinicalTrials.gov Identifier: NCT00179335 - Recruiting
  HIV Infections
  
• High Dose Ritonavir/Lopinavir Liquid Formulation in Salvage Therapy for Protease Inhibitor Resistant HIV Disease
  ClinicalTrials.gov Identifier: NCT00247143 - Recruiting
  HIV; AIDS
  
• NRTI-Sparing Pilot Study
  ClinicalTrials.gov Identifier: NCT00143689 - Active, not recruiting
  HIV; Mitochondrial Toxicity
  
• Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth
  ClinicalTrials.gov Identifier: NCT00102960 - Active, not recruiting
  HIV Infections
  
• Effect of HIV Protease Inhibitor Drugs on Glucose and Insulin Metabolism.
  ClinicalTrials.gov Identifier: NCT00135434 - Completed
  HIV
  
• Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients
  ClinicalTrials.gov Identifier: NCT00050895 - Active, not recruiting
  HIV Infections
  
• A 48 week study comparing treatment with saquinavir + lopinavir/ritonavir in combination with enfuvirtide HAART versus saquinavir + lopinavir/ritonavir + other nucleoside combinations to see the efficacy of these treatments in patients infected with HIV-1
  ClinicalTrials.gov Identifier: NCT00100984 - Terminated
  HIV
  
• Comparison of Treatment Simplification by LPV/r Vs Current Treatment Continuation in HIV-Infected Patients
  ClinicalTrials.gov Identifier: NCT00140751 - Active, not recruiting
  HIV Seropositivity
  
• A Study to Compare Anti-HIV Drugs Given Twice a Day or Once a Day, With or Without Direct Observation
  ClinicalTrials.gov Identifier: NCT00036452 - Active, not recruiting
  HIV Infections
  
• A Multicenter Study to Assess the Tolerability of Once Daily Lopinavir/Ritonavir (LPV/r) Liquid Versus Capsules
  ClinicalTrials.gov Identifier: NCT00281606 - Not yet recruiting
  HIV Infection
  
• A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy
  ClinicalTrials.gov Identifier: NCT00102206 - Active, not recruiting
  HIV Infections
  
• A simplified Kaletra® (lopinavir/ritonavir)-based therapy versus a Sustiva® (efavirenz)-based standard of care in previously non-treated HIV-infected subjects
  ClinicalTrials.gov Identifier: NCT00075231 - Completed
  HIV Infections
  
• Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children
  ClinicalTrials.gov Identifier: NCT00260078 - Active, not recruiting
  HIV Infections
  
• A Study of Lopinavir/Ritonavir Tablets Comparing Once-Daily Versus Twice-Daily Dosing in Antiretroviral-Experienced, HIV-1 Infected Subjects
  ClinicalTrials.gov Identifier: NCT00358917 - Recruiting
  HIV Infection
  
• Anti-HIV Treatment Interruptions in HIV Infected Adults in South Africa
  ClinicalTrials.gov Identifier: NCT00100646 - Active, not recruiting
  HIV Infections
  
• Lopinavir/Ritonavir Monotherapy vs Standard HAART in HIV/HCV Coinfected Patients Starting Treatment With Anti HCV Therapy
  ClinicalTrials.gov Identifier: NCT00437684 - Recruiting
  HIV Infections; Hepatitis C
  
• Lopinavir/Ritonavir Monotherapy vs Standard HAART in HIV/HCV Coinfected ARV Naive Patients Starting Treatment With Anti HCV Therapy
  ClinicalTrials.gov Identifier: NCT00437476 - Recruiting
  HIV Infections; Hepatitis C
  
• Open Label, 48 Week Study of the Ability of Lopinavir/Ritonavir to Influence the Immune Response in Patients Who Are on an HIV Suppressive Regimen But Have Demonstrated a Blunted Immune Recovery.
  ClinicalTrials.gov Identifier: NCT00344487 - Recruiting
  HIV
  
• Safety and Effectiveness of Lopinavir/Ritonavir in Individuals Who Have Failed Prior HIV Therapy
  ClinicalTrials.gov Identifier: NCT00357552 - Not yet recruiting
  HIV Infections
  
• Comparison of Anti-HIV Drug Combinations to Prevent Mother-to-Child Transmission of HIV
  ClinicalTrials.gov Identifier: NCT00086359 - Active, not recruiting
  HIV Infections
  
• A Study of ABT-378/Ritonavir Combination in HIV-Infected Patients Who Have Taken Protease Inhibitors
  ClinicalTrials.gov Identifier: NCT00004580 - Completed
  HIV Infections
  
• Nine Month Course of Anti-HIV Medications for People Recently Infected with HIV
  ClinicalTrials.gov Identifier: NCT00090779 - Recruiting
  HIV Infections
  
• When to Start Anti-HIV Drugs in Children Infected With HIV
  ClinicalTrials.gov Identifier: NCT00234091 - Recruiting
  HIV Infections
  
• Study of the 48-Week Virologic and Immunologic Response to Lopinavir/ritonavir (Kaletra) in HIV Positive Adult Patients
  ClinicalTrials.gov Identifier: NCT00116636 - Recruiting
  HIV Infections
  
• Anti-HIV Drug Regimens With or Without Protease Inhibitors and Drug Level Monitoring in HIV Infected Adolescents
  ClinicalTrials.gov Identifier: NCT00075907 - Active, not recruiting
  HIV Infections
  
• ABT-378/Ritonavir and Efavirenz in HIV-Infected Patients Who Have Taken More Than One Protease Inhibitor in the Past
  ClinicalTrials.gov Identifier: NCT00004582 - Completed
  HIV Infections
  
• Study of Anti-HIV Therapy Intensification
  ClinicalTrials.gov Identifier: NCT00034086 - Active, not recruiting
  HIV Infections
  
• Emtricitabine Given Once A Day with Other Anti-HIV Drugs in Children with HIV
  ClinicalTrials.gov Identifier: NCT00017992 - Recruiting
  HIV Infections
  
• NNRTI- Versus PI-Containing Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child Transmission of HIV
  ClinicalTrials.gov Identifier: NCT00089505 - Recruiting
  HIV Infections
  
• Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women who Take Nevirapine During Pregnancy
  ClinicalTrials.gov Identifier: NCT00099632 - Recruiting
  HIV Infections
  
• Antiviral Responses to a Nevirapine-Based Regimen Versus a Lopinavir/Ritonavir-Based Regimen in HIV Infected Infants Who Have or Have Not Received Single Dose Nevirapine for the Prevention of Mother-to-Child Transmission of HIV
  ClinicalTrials.gov Identifier: NCT00307151 - Recruiting
  HIV Infections
  
• Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving Birth
  ClinicalTrials.gov Identifier: NCT00109590 - Recruiting
  HIV Infections
  
• When to Start Anti-HIV Drugs in Patients with Opportunistic Infections
  ClinicalTrials.gov Identifier: NCT00055120 - Active, not recruiting
  HIV Infections; AIDS-Related Opportunistic Infections
  
• Randomized, Open-Label, Comparative Safety and Efficacy Study of Tipranavir Boosted with Low-Dose Ritonavir (TPV/RTV) Versus Genotypically-Defined Protease Inhibitor/Ritonavir (PI/RTV) in Multiple Antiretroviral Drug-Experienced Patients (RESIST 2)
  ClinicalTrials.gov Identifier: NCT00144170 - Active, not recruiting
  HIV Infections
  
• BOOST: Study of Increased Dosage of Lopinavir/Ritonavir (LPV/r)
  ClinicalTrials.gov Identifier: NCT00414284 - Completed
  HIV Infections
  
• PI Vs. NNRTI Based Therapy for HIV Advanced Disease
  ClinicalTrials.gov Identifier: NCT00162643 - Recruiting
  Acquired Immunodeficiency Syndrome
  
• Comparing the Effectiveness of a Triple Nucleoside Reverse Transcriptase Inhibitor Regimen Versus a Protease Inhibitor-Based Regimen In the Prevention of Mother-to-Child Transmission of HIV
  ClinicalTrials.gov Identifier: NCT00270296 - Recruiting
  HIV Infections
  
• A Phase 3 Study Comparing Two Boosted Protease Inhibitor-Based HAART Regimens in HIV-Infected Patients Experiencing Their First Virologic Failure While Receiving an NNRTI-Containing HAART Regimen
  ClinicalTrials.gov Identifier: NCT00135395 - Completed
  HIV/AIDS
  
• Ritonavir-Boosted GS-9137 Vs. Ritonavir-Boosted Protease Inhibitor(s) in Combination With Background ART.
  ClinicalTrials.gov Identifier: NCT00298350 - Active, not recruiting
  HIV; HIV-1; Human Immunodeficiency Virus
  
• Evaluation of Four Anti-HIV Treatment Strategies in Resource-Limited South African Communities
  ClinicalTrials.gov Identifier: NCT00255840 - Active, not recruiting
  HIV Infections
  
• A Multi-Centre, Double-Blinded, Randomized, Placebo-Controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory Syndrome
  ClinicalTrials.gov Identifier: NCT00578825 - Not yet recruiting
  Severe Acute Respiratory Syndrome
  
• A Study of Ritonavir (an Anti-HIV Drug) in HIV-Positive Infants and Children
  ClinicalTrials.gov Identifier: NCT00000952 - Active, not recruiting
  HIV Infections
  
• The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment
  ClinicalTrials.gov Identifier: NCT00005118 - Active, not recruiting
  HIV Infections
  
• Study of HIV Patients with Undetectable Viral Load and Abnormal Lipids Switching to Atazanavir/Ritonavir
  ClinicalTrials.gov Identifier: NCT00120393 - Active, not recruiting
  HIV Infections
  
• The Effect of Lopinavir/Ritonavir on Endothelial Function
  ClinicalTrials.gov Identifier: NCT00076414 - Completed
  Healthy
  
• Pharmacokinetic Study of Rosuvastatin and Lopinavir/Ritonavir in HIV Patients
  ClinicalTrials.gov Identifier: NCT00184951 - Completed
  HIV Infections; Hyperlipidemia
  
• Effectiveness of ABT-378/Ritonavir Plus Lamivudine Plus Efavirenz Plus Tenofovir DF in HIV-Infected Patients
  ClinicalTrials.gov Identifier: NCT00038220 - Completed
  HIV Infections
  
• Trial of TMC114/Ritonavir (RTV) in HIV-1 Infected Treatment Experienced Subjects
  ClinicalTrials.gov Identifier: NCT00081588 - Active, not recruiting
  HIV Infections
  
• Salvage Therapy With Amprenavir, Lopinavir and Ritonavir in HIV-Infected Patients in Virological Failure.
  ClinicalTrials.gov Identifier: NCT00196625 - Completed
  HIV Infections
  
• Study of TMC114 and Low Dose Ritonavir in HIV-1 Infected Subjects
  ClinicalTrials.gov Identifier: NCT00071097 - Active, not recruiting
  HIV Infections
  
• Ritonavir and Agenerase Treatment for Patients Who Have Failed Previous Anti-HIV Treatment
  ClinicalTrials.gov Identifier: NCT00006591 - Active, not recruiting
  HIV Infections
  
• Tipranavir/Ritonavir in HIV Patients with Limited Treatment Options
  ClinicalTrials.gov Identifier: NCT00062660 - Active, not recruiting
  HIV Infections
  
• A Randomized Trial of the Efficacy and Safety of a Strategy of Starting with Nelfinavir Versus Ritonavir Added to Background Antiretroviral (AR) Nucleoside Therapy in HIV-Infected Individuals with CD4+ Cell Counts Less than or Equal to 200/mm3
  ClinicalTrials.gov Identifier: NCT00000859 - Active, not recruiting
  HIV Infections
  
• Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs
  ClinicalTrials.gov Identifier: NCT00006397 - Active, not recruiting
  HIV Infections
  
• A 48-Week, Randomised, Study to Describe the Pharmacokinetic Profile and Durability of Atazanavir-Saquinavir-Ritonavir Once Daily and Describe the Pharmacokinetic Profile of Saquinavir-Ritonavir Using Saquinavir 500mg Formulation: the ASK-500 Study
  ClinicalTrials.gov Identifier: NCT00192608 - Active, not recruiting
  HIV Infections
  
• Ritonavir and Indinavir in Children Failing Other Anti-HIV Treatment
  ClinicalTrials.gov Identifier: NCT00012519 - Active, not recruiting
  HIV Infections
  
• Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
  ClinicalTrials.gov Identifier: NCT00002451 - Active, not recruiting
  HIV Infections
  
• Comparison of GW433908/Ritonavir to Nelfinavir When Used with Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs
  ClinicalTrials.gov Identifier: NCT00009061 - Active, not recruiting
  HIV Infections
  
• Atazanavir/Ritonavir Maintenance Therapy
  ClinicalTrials.gov Identifier: NCT00084019 - Active, not recruiting
  HIV Infections
  
• A Study Exploring an Induction-Maintenance Kaletra-Based Therapy Versus a Sustiva-Based Regimen in Previously Non-Treated, HIV-1/HCV Co-Infected Subjects
  ClinicalTrials.gov Identifier: NCT00121017 - Not yet recruiting
  HIV Infection; Hepatitis C
  
• Tipranavir in Combination with Ritonavir in HIV-Infected Children
  ClinicalTrials.gov Identifier: NCT00076999 - Active, not recruiting
  HIV Infections
  
• Study Comparing Efficacy and Safety of Darunavir Boosted With Ritonavir to HART With 2 NRTI and Darunavir Boosted With Ritonavir in HIV-1 Infected Patients
  ClinicalTrials.gov Identifier: NCT00421551 - Recruiting
  HIV Infections
  
• Amprenavir/Ritonavir, Saquinavir/Ritonavir or Efavirenz in HIV-Infected Patients Following Failure with Kaletra (ABT-378/Ritonavir) as Their First Protease Inhibitor Based HAART
  ClinicalTrials.gov Identifier: NCT00038532 - Completed
  HIV Infections
  
• A PK Study of a Combination of Indinavir, Ritonavir and Amprenavir
  ClinicalTrials.gov Identifier: NCT00148785 - Recruiting
  Antiretroviral drugs
  
• Dual Boosted - Protease Inhibitor (PI) Pharmacokinetics (PK) Trial
  ClinicalTrials.gov Identifier: NCT00056641 - Completed
  HIV Infections
  
• Treatment Simplification by Darunavir/Ritonavir 800/100 mg Once a Day Versus a Triple Combination Therapy With Darunavir/Ritonavir
  ClinicalTrials.gov Identifier: NCT00458302 - Recruiting
  Acquired Immunodeficiency Syndrome Virus; HIV Infections; AIDS Virus; Human Immunodeficiency Virus
  
• 48-Week Study Of GW433908 And Ritonavir Or GW433908 Alone, Twice Daily In Pediatric Patients With HIV Infection
  ClinicalTrials.gov Identifier: NCT00089583 - Recruiting
  HIV Infections
  
• Efavirenz Or Atazanazir/Ritonavir Given with Emtricitabine/Tenofovir Disoproxil Fumarate Or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
  ClinicalTrials.gov Identifier: NCT00118898 - Active, not recruiting
  HIV Infections