Ketotifen Fumarate Ophthalmic |
ketotifen fumarate; Zaditor |
Ketotifen Systematic (IUPAC) name 4,9-dihydro-4-(1-methyl-4-piperidinylidene)- 10H-benzocyclohepta[1,2-b]thiopen-10-one Identifiers CAS number 34580-14-8 ATC code R06AX17 S01GX08 PubChem 3827 DrugBank APRD01061 Chemical data Formula C19H19NOS Mol. weight 309.426 g/mol Pharmacokinetic data Bioavailability 60% Protein binding 75% Metabolism Hepatic Half life 21 Hours Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status ...
Wikipedia - [full article]
Ketotifen Fumarate Ophthalmic Clinical Trials
- Safety and Efficacy Comparison Ketotifen Ophthalmic Solution with Emedastine in Patients with Seasonal Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00133627 - Completed
Seasonal allergic conjunctivitis
- Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
ClinicalTrials.gov Identifier: NCT00569777 - Active, not recruiting
Allergic Conjunctivitis
- TOBRADEX Ophthalmic Suspension Versus Tobramycin 0.3%/Dexamethasone 0.05% Ophthalmic Suspension
ClinicalTrials.gov Identifier: NCT00576251 - Recruiting
Ocular Inflammation Associated With Blepharaconjunctivitis
- The Safety of Tenofovir Disoproxil Fumarate Taken with Other Anti-HIV Drugs to Treat HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00007436 - Active, not recruiting
HIV Infections
- Tenofovir Disoproxil Fumarate in HIV-Infected Patients Who Have Not Had Success with Other Anti-HIV Drug Combinations
ClinicalTrials.gov Identifier: NCT00011089 - Active, not recruiting
HIV Infections
- Study of Treatment of Antiretroviral-Naive, HIV-1-Infected Patients Comparing Tenofovir Disoproxil Fumarate Administered in Combination with Lamivudine and Efavirenz Vs. Stavudine, Lamivudine and Efavirenz.
ClinicalTrials.gov Identifier: NCT00158821 - Active, not recruiting
HIV-1
- Tenofovir Disoproxil Fumarate (DF)/Emtricitabine/Efavirenz Versus Combivir/Efavirenz in Antiretroviral-Naive HIV-1 Infected Subjects
ClinicalTrials.gov Identifier: NCT00112047 - Active, not recruiting
HIV Infections
- Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug Therapy
ClinicalTrials.gov Identifier: NCT00109603 - Active, not recruiting
HIV Infections; Dyslipidemia; Hyperlipidemia; Hypercholesterolemia; Hypertriglyceridemia
- Safety and Blood Levels of Tenofovir Disoproxil Fumarate in HIV Infected Pregnant Women and Their Babies
ClinicalTrials.gov Identifier: NCT00120471 - Recruiting
HIV Infections
- Efavirenz Or Atazanazir/Ritonavir Given with Emtricitabine/Tenofovir Disoproxil Fumarate Or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
ClinicalTrials.gov Identifier: NCT00118898 - Active, not recruiting
HIV Infections
- Safety of Tenofovir Disoproxil Fumarate (TDF) in HIV Infected Pregnant Women and Their Infants
ClinicalTrials.gov Identifier: NCT00076791 - Recruiting
HIV Infections
- Immediate Versus Deferred Start of Anti-HIV Therapy in HIV Infected Adults Being Treated for Tuberculosis
ClinicalTrials.gov Identifier: NCT00108862 - Recruiting
HIV Infections; Tuberculosis
- Study of Efficacy and Safety of Seroquel (Quetiapine Fumarate) as Mono-Therapy for Acute Schizophrenic
ClinicalTrials.gov Identifier: NCT00428350 - Active, not recruiting
Schizophrenia
- Effectiveness of Nucleoside Supplementation and Substituting Tenofovir Disoproxil Fumarate for Other Drugs in Anti-HIV Regimens in Reversing Fat Loss in HIV Infected Adults
ClinicalTrials.gov Identifier: NCT00119379 - Recruiting
HIV Infections; Lipodystrophy; Metabolic Diseases; Nutrition Disorders
- Combigan Ophthalmic Solution(Brimonidine 0.2% and Timolol 0.5%)With Latanoprost Compared With Latanoprost Monotherapy
ClinicalTrials.gov Identifier: NCT00442312 - Active, not recruiting
Glaucoma
- Phase III, Long-Term, Open-Label, Extension Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis
ClinicalTrials.gov Identifier: NCT00567918 - Active, not recruiting
Keratoconjunctivitis; Conjunctivitis
- One Hour Preoperative Gatifloxacin
ClinicalTrials.gov Identifier: NCT00350363 - Recruiting
Ophthalmic Surgery
- The Safety and Effectiveness of PMPA Prodrug in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002396 - Active, not recruiting
HIV Infections
- Montelukast Post-Marketing Comparative Study With Ketotifen
ClinicalTrials.gov Identifier: NCT00446056 - Completed
Asthma
- Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome
ClinicalTrials.gov Identifier: NCT00370747 - Active, not recruiting
Dry Eye Syndromes
- Evaluation of the Onset and Duration of Action of Bepotastine Besilate Ophthalmic Solution in Acute Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00424398 - Active, not recruiting
Conjunctivitis, Allergic
- Safety/Efficacy of Bromfenac Ophthalmic Solution for Ocular Inflammation and Pain Associated With Cataract Surgery
ClinicalTrials.gov Identifier: NCT00333918 - Active, not recruiting
Pain; Inflammation
- Efficacy and Safety of Topical Bromfenac Ophthalmic Solution vs. Placebo in Subjects With Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00423007 - Active, not recruiting
Allergic Conjunctivitis
- Evaluation of Efficacy of Ophthalmic Solution in Induced Acute Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00241319 - Active, not recruiting
Allergic Conjunctivitis
- Quetiapine Fumarate (SEROQUEL) in the Treatment of Adolescent Patients With Schizophrenia and Bipolar I Disorder
ClinicalTrials.gov Identifier: NCT00227305 - Active, not recruiting
Schizophrenia; Bipolar I Disorder
- Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients
ClinicalTrials.gov Identifier: NCT00050895 - Active, not recruiting
HIV Infections
- Extended Safety Study of Tenofovir Disoproxil Fumarate (TDF) Among HIV-1 Negative Men
ClinicalTrials.gov Identifier: NCT00131677 - Active, not recruiting
HIV Infection
- Evaluation of Efficacy of Ophthalmic Solution in Induced Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00244543 - Active, not recruiting
Allergic Conjunctivitis
- Evaluation of Efficacy of Ophthalmic Solution in Seasonal Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00364091 - Active, not recruiting
Allergic Conjunctivitis
- A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy
ClinicalTrials.gov Identifier: NCT00102206 - Active, not recruiting
HIV Infections
- Anti-HIV Drugs During Pregnancy
ClinicalTrials.gov Identifier: NCT00042289 - Active, not recruiting
HIV Infections
- Evolution of L74V or K65R Mutations in VIremic Subjects on Tenofovir Disoproxil Fumarate (TDF) or Abacavir (ABC) (EVITA)
ClinicalTrials.gov Identifier: NCT00312169 - Recruiting
HIV Infections
- Late Phase 2 Study of OPC-12759 Ophthalmic Suspension
ClinicalTrials.gov Identifier: NCT00475319 - Recruiting
Dry Eye Syndromes
- Once-Daily PI/NNRTI Therapy Combinations for Treatment Naive, HIV Infected Patients in Resource-limited Conditions
ClinicalTrials.gov Identifier: NCT00084136 - Active, not recruiting
HIV Infections
- Quetiapine Fumarate (SEROQUEL) and Placebo in the Treatment of Acutely Ill Patients with Schizophrenia
ClinicalTrials.gov Identifier: NCT00085891 - Completed
Schizophrenia
- Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men
ClinicalTrials.gov Identifier: NCT00458393 - Recruiting
HIV Infections
- Safety Study of Ophthalmic Solution in Healthy, Normal Volunteers
ClinicalTrials.gov Identifier: NCT00223951 - Active, not recruiting
Healthy Volunteers Eligible for Study; Drug Being Developed for Allergic Conjunctivitis
- Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Adolescent Patients with Schizophrenia
ClinicalTrials.gov Identifier: NCT00090324 - Completed
Schizophrenia
- Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIV
ClinicalTrials.gov Identifier: NCT00027339 - Active, not recruiting
HIV Infections
- Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Children and Adolescent Patients with Bipolar I Mania
ClinicalTrials.gov Identifier: NCT00090311 - Completed
Bipolar Disorder
- Examining The Efficacy, Safety And Improved Tolerability Of Travoprost BAK Free Ophthalmic Solution (Travatan-Z) Compared To Prior Prostaglandin Therapy
ClinicalTrials.gov Identifier: NCT00444665 - Recruiting
Glaucoma
- Evaluation and Treatment Protocol for Potential Research Participants With Inherited Ophthalmic Diseases
ClinicalTrials.gov Identifier: NCT00559234 - Recruiting
Cataract; Glaucoma; Retinitis Pigmentosa; Macular Degeneration; Strabismus
- A Study to Compare Tenofovir Versus Hepsera (Adefovir) for the Treatment of HBeAg Negative Chronic Hepatitis B
ClinicalTrials.gov Identifier: NCT00117676 - Active, not recruiting
Chronic Hepatitis B
- Study of Anti-HIV Therapy Intensification
ClinicalTrials.gov Identifier: NCT00034086 - Active, not recruiting
HIV Infections
- A Study to Compare Tenofovir versus Hepsera (adefovir) for the Treatment of Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B
ClinicalTrials.gov Identifier: NCT00116805 - Active, not recruiting
Chronic Hepatitis B
- Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine/TDF, & Entecavir in the Treatment of Chronic HBV in Subjects w/Decompensated Liver Disease.
ClinicalTrials.gov Identifier: NCT00298363 - Recruiting
Chronic Hepatitis B
- Nine Month Course of Anti-HIV Medications for People Recently Infected with HIV
ClinicalTrials.gov Identifier: NCT00090779 - Recruiting
HIV Infections
- Quetiapine Fumarate (SEROQUEL) used as an Adjunct to Mood Stabilizers in the Treatment of Bipolar I Disorders
ClinicalTrials.gov Identifier: NCT00107731 - Completed
Bipolar Disorder
- Repository for Inherited Eye Diseases
ClinicalTrials.gov Identifier: NCT00378742 - Recruiting
Retinitis Pigmentosa; Inherited Ophthalmic Diseases
- Using Device Delivering Ophthalmic Solution in a Spray Form Instead of Eye Drops
ClinicalTrials.gov Identifier: NCT00565630 - Not yet recruiting
Cataract
- Study of INS365 Ophthalmic Solution in a Controlled Adverse Environment in Patients with Dry Eye
ClinicalTrials.gov Identifier: NCT00037661 - Completed
Keratoconjunctivitis Sicca
- NNRTI- Versus PI-Containing Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child Transmission of HIV
ClinicalTrials.gov Identifier: NCT00089505 - Recruiting
HIV Infections
- Safety and Effectiveness of Tenofovir Disoproxil Fumarate (Tenofovir DF) Plus Other Anti-HIV Drugs in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002450 - Completed
HIV Infections
- Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women who Take Nevirapine During Pregnancy
ClinicalTrials.gov Identifier: NCT00099632 - Recruiting
HIV Infections
- Safety Study of Bromfenac Ophthalmic Solution in Subjects With Diffuse Diabetic Macular Edema (DME) Refractory to Laser
ClinicalTrials.gov Identifier: NCT00491166 - Recruiting
Diabetic Macular Edema
- Study of Tenofovir Disoproxil Fumarate (TDF) for Prevention of HIV
ClinicalTrials.gov Identifier: NCT00122486 - Completed
HIV Infections
- Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma
ClinicalTrials.gov Identifier: NCT00443924 - Recruiting
Ocular Hypertension; Open Angle Glaucoma
- A Compassionate Use Study of Tenofovir Disoproxil Fumarate as Treatment for HIV Infection
ClinicalTrials.gov Identifier: NCT00002453 - Completed
HIV Infections
- Evaluating Quetiapine Fumarate (SEROQUEL) in the Treatment of Alcohol Dependency in Patients with Bipolar Disorder
ClinicalTrials.gov Identifier: NCT00114686 - Completed
Bipolar Disorder; Alcoholism
- Safety and Efficacy Trial of the Use of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Patients with Bipolar Depression
ClinicalTrials.gov Identifier: NCT00060489 - Completed
Bipolar Disorder; Depression, Bipolar
- Tenofovir Disoproxil Fumarate (TDF) in HIV-1 Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00016588 - Completed
HIV Infections
- IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension
ClinicalTrials.gov Identifier: NCT00527501 - Recruiting
Open-Angle Glaucoma; Ocular Hypertension
- Effectiveness and Safety of Tiotropium Bromide Alone Vs Tiotropium Bromide and Formoterol Fumarate in Subjects with COPD
ClinicalTrials.gov Identifier: NCT00139932 - Completed
Pulmonary Disease, Chronic Obstructive
- Quetiapine Treatment for Symptoms Associated with Borderline Personality Disorder
ClinicalTrials.gov Identifier: NCT00122070 - Recruiting
Borderline Personality Disorder
- Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma
ClinicalTrials.gov Identifier: NCT00079417 - Recruiting
intraocular retinoblastoma
- Phase IV study of TRAVATAN 0.004% in subjects with iris pigmentation changes
ClinicalTrials.gov Identifier: NCT00047554 - Recruiting
Open-Angle Glaucoma; Ocular Hypertension
- Systemic Vincristine, Carboplatin, and Etoposide, Subtenon Carboplatin, and Local Ophthalmic Therapy With or Without Low-Dose Radiation Therapy in Treating Children With Intraocular Retinoblastoma
ClinicalTrials.gov Identifier: NCT00072384 - Recruiting
intraocular retinoblastoma
- A Study Exploring an Induction-Maintenance Kaletra-Based Therapy Versus a Sustiva-Based Regimen in Previously Non-Treated, HIV-1/HCV Co-Infected Subjects
ClinicalTrials.gov Identifier: NCT00121017 - Not yet recruiting
HIV Infection; Hepatitis C
- Bioavailability of Bimatoprost Ophthalmic Solution in Human Aqueous.
ClinicalTrials.gov Identifier: NCT00355446 - Completed
Cataract
- Next Generation Ophthalmic Irrigating Solution Posterior Segment Study
ClinicalTrials.gov Identifier: NCT00333203 - Completed
Eye Diseases
- Safety and Efficacy of Next Generation Ophthalmic Irrigating Solution Compared to BSS Plus
ClinicalTrials.gov Identifier: NCT00333268 - Completed
Cataract
- Dose-Response Study of OPC-12759 Ophthalmic Suspension
ClinicalTrials.gov Identifier: NCT00234078 - Completed
Dry Eye Syndromes
- Study of Tenofovir Disoproxil Fumarate (TDF) for Prevention of HIV
ClinicalTrials.gov Identifier: NCT00122512 - Terminated
Human Immunodeficiency Virus
- Dose Finding of Quetiapine Fumarate 200mg vs 400mg in First Episode Psychosis
ClinicalTrials.gov Identifier: NCT00449397 - Completed
Psychosis
- Study of Mometasone Furoate/Formoterol Fumarate Inhalation Combination in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00418509 - Completed
Healthy
- Effect of Brimonidine Tartrate Ophthalmic Solution 0.15% on Pupil Diameter in Normal Eyes
ClinicalTrials.gov Identifier: NCT00413751 - Completed
Healthy
- Quetiapine Fumarate Bipolar Maintenance Monotherapy
ClinicalTrials.gov Identifier: NCT00314184 - Completed
Bipolar Disorder
- Safety and Tolerability of Ciclesonide and Formoterol Fumarate Inhaled Once Daily in Patients With Asthma (18 to 75 y) (BY9010/M1-506)
ClinicalTrials.gov Identifier: NCT00314509 - Completed
Asthma
- A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients with Open-Angle Glaucoma or Ocular Hypertension
ClinicalTrials.gov Identifier: NCT00061529 - Completed
Open-Angle Glaucoma; Ocular Hypertension
- Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients
ClinicalTrials.gov Identifier: NCT00352807 - Completed
Cataract
- Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis
ClinicalTrials.gov Identifier: NCT00406887 - Completed
Anterior Uveitis; Panuveitis
- Study of Difluprednate Ophthalmic Emulsion in the Treatment of Severe Uveitis
ClinicalTrials.gov Identifier: NCT00407056 - Completed
Uveitis; Panuveitis
- Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis
ClinicalTrials.gov Identifier: NCT00405496 - Completed
Anterior Uveitis
- Study of Difluprednate Ophthalmic Emulsion in the Treatment of Postoperative Inflammation
ClinicalTrials.gov Identifier: NCT00406497 - Completed
Inflammation
- Study of Difluprednate Ophthalmic Emulsion in the Treatment of Postoperative Inflammation
ClinicalTrials.gov Identifier: NCT00407225 - Completed
Inflammation
- Study of Difluprednate Ophthalmic Emulsion in Postoperative Inflammation
ClinicalTrials.gov Identifier: NCT00406341 - Completed
Inflammation
- Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis
ClinicalTrials.gov Identifier: NCT00567762 - Completed
Keratoconjunctivitis; Conjunctivitis
- Role of Metabolites in Nicotine Dependence (4) - 13
ClinicalTrials.gov Identifier: NCT00000296 - Completed
Tobacco Use Disorder
- Role of Metabolites in Nicotine Dependence (1) - 1
ClinicalTrials.gov Identifier: NCT00000284 - Completed
Tobacco Use Disorder
- Role of Metabolites in Nicotine Dependence (2) - 5
ClinicalTrials.gov Identifier: NCT00000288 - Completed
Tobacco Use Disorder
- Efficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in the Treatment of Major Depressive Disorders
ClinicalTrials.gov Identifier: NCT00326144 - Completed
Major Depressive Disorder
- Efficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in Combination With an Antidepressant in the Treatment of Major Depressive Disorders
ClinicalTrials.gov Identifier: NCT00326105 - Completed
Major Depressive Disorder
- Confirmatory Study of Seroquel® in the Treatment of Bipolar Depression
ClinicalTrials.gov Identifier: NCT00083954 - Completed
Bipolar Disorder
- Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo and Active Control in Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00321490 - Completed
Major Depressive Disorder
- A comparison of Seroquel vs. Risperidone in Schizophrenia
ClinicalTrials.gov Identifier: NCT00034905 - Completed
Schizophrenia
- Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00320268 - Completed
Major Depressive Disorder
- Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Generalized Anxiety Disorder
ClinicalTrials.gov Identifier: NCT00329264 - Completed
Generalized Anxiety Disorder
- Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome
ClinicalTrials.gov Identifier: NCT00198536 - Completed
Dry Eye Syndromes
- A Comparison of Two Drug Combinations Used in HIV-Infected Patients Who Never Have Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00005573 - Completed
HIV Infections
- Study of Efficacy of Levofloxacin 0.5% Ophthalmic Solution Administered Three Times a Day for Bacterial Conjunctivitis
ClinicalTrials.gov Identifier: NCT00565123 - Completed
Bacterial Conjunctivitis

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