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Procarbazine |
Matulane |
Procarbazine Systematic (IUPAC) name N-(1-methylethyl)-4-[(N'-methylhydrazino)methyl]benzamide Identifiers CAS number 671-16-9 ATC code L01XB01 PubChem 4915 DrugBank APRD00695 Chemical data Formula C12H19N3O Mol. weight 221.299 g/mol Pharmacokinetic data Bioavailability ? Metabolism Hepatic, Renal Half life 10 minutes Excretion Renal Therapeutic considerations Pregnancy cat. D(US) Legal status ℞ Prescription only Routes Oral (Gel ...
Wikipedia - [full article]
Procarbazine Clinical Trials
- Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma
ClinicalTrials.gov Identifier: NCT00074191 - Active, not recruiting
intraocular lymphoma; primary central nervous system lymphoma
- Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas
ClinicalTrials.gov Identifier: NCT00003564 - Active, not recruiting
adult glioblastoma multiforme; adult anaplastic astrocytoma; adult anaplastic oligodendroglioma; recurrent adult brain tumor; Mixed Gliomas
- Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
ClinicalTrials.gov Identifier: NCT00005796 - Active, not recruiting
Brain Tumor
- Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma
ClinicalTrials.gov Identifier: NCT00052455 - Recruiting
adult glioblastoma; adult anaplastic astrocytoma; recurrent adult brain tumor; adult giant cell glioblastoma; adult gliosarcoma
- Methotrexate and Temozolomide Versus Methotrexate, Procarbazine, Vincristine and Cytarabine
ClinicalTrials.gov Identifier: NCT00503594 - Recruiting
Lymphoma
- Oral Combination Chemotherapy in Treating Elderly Patients With Intermediate or High-Grade Non-Hodgkin's Lymphomas
ClinicalTrials.gov Identifier: NCT00003113 - Active, not recruiting
Lymphoma
- Combination Chemotherapy and Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Oligodendroglioma
ClinicalTrials.gov Identifier: NCT00003101 - Active, not recruiting
adult anaplastic oligodendroglioma; adult well-differentiated oligodendroglioma; Adult Oligodendroglioma
- Vinblastine, Cyclophosphamide, Procarbazine, Prednisolone, Etoposide, Mitoxantrone, and Bleomycin in Treating Older Patients With Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00079105 - Recruiting
stage I adult Hodgkin's lymphoma; stage II adult Hodgkin's lymphoma; stage III adult Hodgkin's lymphoma; stage IV adult Hodgkin's lymphoma
- Combination Chemotherapy in Treating Patients With AIDS-Related Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00003114 - Active, not recruiting
HIV-associated Hodgkin's disease; AIDS-Related Lymphoma
- Phase II Study of RT-PEPC in Relapsed Mantle Cell Lymphoma
ClinicalTrials.gov Identifier: NCT00151281 - Recruiting
Non-Hodgkin''s Lymphoma
- Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma
ClinicalTrials.gov Identifier: NCT00003375 - Active, not recruiting
Adult Oligodendroglioma; adult noninfiltrating astrocytoma; adult infiltrating astrocytoma
- Immunotherapy Combined With Chemotherapy Followed by Radiation Therapy and Chemotherapy in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
ClinicalTrials.gov Identifier: NCT00059956 - Active, not recruiting
primary central nervous system lymphoma
- Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma
ClinicalTrials.gov Identifier: NCT00002840 - Active, not recruiting
adult anaplastic oligodendroglioma; Mixed Gliomas; recurrent adult brain tumor
- Procarbazine in Treating Patients With Recurrent Brain Tumor
ClinicalTrials.gov Identifier: NCT00004004 - Completed
Brain Tumor; Oligodendroglioma; Glioblastoma; Astrocytoma
- Chemotherapy, Filgrastim, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma
ClinicalTrials.gov Identifier: NCT00003929 - Active, not recruiting
AIDS-related primary CNS lymphoma; primary central nervous system lymphoma
- Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas
ClinicalTrials.gov Identifier: NCT00003788 - Active, not recruiting
recurrent adult brain tumor; adult glioblastoma multiforme; adult anaplastic astrocytoma
- Combination Chemotherapy in Treating Children With Progressive Brain Tumors
ClinicalTrials.gov Identifier: NCT00002944 - Active, not recruiting
recurrent childhood brain stem glioma; recurrent childhood visual pathway glioma; recurrent childhood cerebellar astrocytoma; ...
- Radiation Therapy or No Radiation Therapy Following Chemotherapy in Treating Patients With Stage III or Stage IV Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00002462 - Active, not recruiting
stage III adult Hodgkin's disease; stage IV adult Hodgkin's disease
- Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00003421 - Active, not recruiting
stage II adult Hodgkin's disease; stage III adult Hodgkin's disease; stage IV adult Hodgkin's disease; stage I adult Hodgkin's disease
- Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors
ClinicalTrials.gov Identifier: NCT00002463 - Active, not recruiting
untreated childhood cerebellar astrocytoma; low-grade childhood cerebral astrocytoma; ...
- SU-101 Compared With Procarbazine in Treating Patients With Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00003293 - Completed
adult glioblastoma multiforme; Quality of Life; recurrent adult brain tumor
- Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00004010 - Active, not recruiting
stage III childhood Hodgkin's disease; stage IV childhood Hodgkin's disease; childhood lymphocyte predominant Hodgkin's disease; ...
- Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplantation in Treating Children With Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00025064 - Active, not recruiting
stage II childhood Hodgkin's lymphoma; stage I childhood Hodgkin's lymphoma; stage III childhood Hodgkin's lymphoma; ...
- Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00049439 - Active, not recruiting
AIDS-related diffuse large cell lymphoma; AIDS-related diffuse mixed cell lymphoma; AIDS-related diffuse small cleaved cell lymphoma; ...
- Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma
ClinicalTrials.gov Identifier: NCT00079092 - Completed
adult anaplastic astrocytoma; adult anaplastic oligodendroglioma; adult brain tumor; adult glioblastoma; Mixed Gliomas
- Intratumoral Transferrin-CRM107 Compared With Best Standard Chemotherapy in Treating Patients With Progressive and/or Recurrent Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00087230 - Recruiting
adult glioblastoma; recurrent adult brain tumor; adult giant cell glioblastoma; adult gliosarcoma
- Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00049595 - Recruiting
adult lymphocyte depletion Hodgkin's lymphoma; adult mixed cellularity Hodgkin's lymphoma; adult nodular sclerosis Hodgkin's lymphoma; ...
- Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma
ClinicalTrials.gov Identifier: NCT00002806 - Completed
adult infiltrating astrocytoma
- Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma
ClinicalTrials.gov Identifier: NCT00002569 - Completed
adult anaplastic oligodendroglioma; Mixed Gliomas
Resources
- Matulane (Drug Digest)
- Procarbazine (Drug Digest)
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