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Mesna |
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Mesna Systematic (IUPAC) name sodium 2-sulfanylethanesulfonate Identifiers CAS number 19767-45-4 ATC code R05CB05 V03AF01 PubChem 29769 Chemical data Formula C2H5O3S2Na Mol. weight 164.181 g/mol Pharmacokinetic data Bioavailability 45–79% (Oral) Metabolism Oxidised in circulation Half life 0.36–8.3 hours Excretion Renal Therapeutic considerations Pregnancy cat. B1 (Au), B (U.S.) Legal status S4 (Au), POM (UK), ℞-only (U.S.) Routes Or ...
Wikipedia - [full article]
Mesna Clinical Trials
- Chemotherapy in Treating Patients With Retinoblastoma
ClinicalTrials.gov Identifier: NCT00002675 - Active, not recruiting
Retinoblastoma
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma
ClinicalTrials.gov Identifier: NCT00002740 - Active, not recruiting
disseminated neuroblastoma
- Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants with Brain Tumors
ClinicalTrials.gov Identifier: NCT00042367 - Active, not recruiting
Brain Tumors
- High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Combination Chemotherapy in Treating Women With High-Risk Breast Cancer
ClinicalTrials.gov Identifier: NCT00002784 - Active, not recruiting
Breast Cancer
- Combination Chemotherapy Followed by Radiation Therapy in Patients With Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00002822 - Active, not recruiting
Carcinoma, Small Cell
- Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma
ClinicalTrials.gov Identifier: NCT00002516 - Active, not recruiting
metastatic tumors of the Ewing's family; localized tumors of the Ewing's family
- High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer
ClinicalTrials.gov Identifier: NCT00002837 - Active, not recruiting
stage IV breast cancer; recurrent breast cancer
- Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00002816 - Active, not recruiting
Quality of Life; recurrent childhood acute lymphoblastic leukemia
- Phase II Study of Hyper-CVAD plus Imatinib Mesylate for Philadelphia-Positive Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00038610 - Active, not recruiting
Leukemia, Lymphocytic, Acute, L2
- Addition of Paclitaxel to High-Dose Combination Chemotherapy in Treating Women With Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00002628 - Active, not recruiting
stage IV breast cancer; recurrent breast cancer
- Chemotherapy, Radiation Therapy, Immunotherapy, and Bone Marrow Transplantation in Treating Patients With Neuroblastoma
ClinicalTrials.gov Identifier: NCT00002634 - Active, not recruiting
disseminated neuroblastoma; regional neuroblastoma; localized resectable neuroblastoma; recurrent neuroblastoma; localized unresectable neuroblastoma
- Anti-Human CD45 Monoclonal Antibodies in Patients with Advanced Leukemia Prior to Allogeneic Stem Cell Transplantation
ClinicalTrials.gov Identifier: NCT00057005 - Recruiting
Leukemia
- Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma
ClinicalTrials.gov Identifier: NCT00002804 - Active, not recruiting
nonmetastatic childhood soft tissue sarcoma; metastatic childhood soft tissue sarcoma
- Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma
ClinicalTrials.gov Identifier: NCT00002802 - Active, not recruiting
stage IVS neuroblastoma; disseminated neuroblastoma; localized unresectable neuroblastoma; regional neuroblastoma; localized resectable neuroblastoma
- High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer
ClinicalTrials.gov Identifier: NCT00002854 - Active, not recruiting
Breast Cancer; Gastrointestinal Cancer; Kidney Cancer; Musculoskeletal Cancer; Reproductive Cancer; Skin Cancer
- Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00002704 - Active, not recruiting
B-cell childhood acute lymphocytic leukemia; TdT positive childhood acute lymphocytic leukemia; recurrent childhood acute lymphocytic leukemia; ...
- Stem Cell Transplantation for Patients with Hematologic Malignancies
ClinicalTrials.gov Identifier: NCT00152139 - Active, not recruiting
Acute Lymphoblastic Leukemias; Acute Myelocytic Leukemia; Chronic Myeloid Leukemia; Juvenile Myelomonocytic Leukemia; Myelodysplastic Syndrome; ...
- High-Dose Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Poor-Prognosis Breast Cancer
ClinicalTrials.gov Identifier: NCT00002509 - Active, not recruiting
stage IIIB breast cancer; stage IIIA breast cancer; stage IV breast cancer; recurrent breast cancer; stage II breast cancer
- Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer
ClinicalTrials.gov Identifier: NCT00003042 - Active, not recruiting
stage IIIB breast cancer; inflammatory breast cancer
- Addition of Paclitaxel to High-Dose Combination Chemotherapy in Treating Patients With High-Risk Breast Cancer
ClinicalTrials.gov Identifier: NCT00002627 - Active, not recruiting
stage IIIB breast cancer; stage IIIA breast cancer; inflammatory breast cancer; stage II breast cancer
- Intensive Chemotherapy and Rituximab in the Treatment of Burkitt Lymphoma
ClinicalTrials.gov Identifier: NCT00126191 - Recruiting
Burkitt Lymphoma; Non-Hodgkins Lymphoma; Atypical Burkitt Lymphoma
- Bone Marrow Transplantation in Treating Patients With Lymphoma
ClinicalTrials.gov Identifier: NCT00002829 - Active, not recruiting
recurrent diffuse small lymphocytic/marginal zone lymphoma; Waldenstrom's Macroglobulinemia; recurrent grade I follicular small cleaved cell lymphoma; ...
- Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
ClinicalTrials.gov Identifier: NCT00002524 - Active, not recruiting
AIDS-related diffuse small cleaved cell lymphoma; AIDS-related small noncleaved cell lymphoma; AIDS-related diffuse mixed cell lymphoma; ...
- Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002549 - Active, not recruiting
adult acute myelomonocytic leukemia (M4); untreated adult acute myeloid leukemia; adult acute differentiated monocytic leukemia (M5b); ...
- Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Hodgkin's or Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002941 - Active, not recruiting
recurrent childhood lymphoblastic lymphoma; childhood diffuse large cell lymphoma; childhood immunoblastic large cell lymphoma; ...
- Chemotherapy and Radiation Therapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002510 - Active, not recruiting
recurrent diffuse small lymphocytic/marginal zone lymphoma; Waldenstrom's Macroglobulinemia; recurrent grade III follicular large cell lymphoma; ...
- Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002494 - Active, not recruiting
stage I adult diffuse small noncleaved cell/Burkitt's lymphoma; noncontiguous stage II adult diffuse small noncleaved cell/Burkitt's lymphoma; ...
- Effects of Mesna on Homocysteine in Kidney Failure
ClinicalTrials.gov Identifier: NCT00524199 - Completed
End Stage Renal Disease
- A Randomized Study of the Effect of Adjuvant Chemotherapy with Doxorubicin and Ifosfamide with Mesna in the Treatment of High-Grade Adult Extremity Soft Tissue Sarcoma
ClinicalTrials.gov Identifier: NCT00001300 - Completed
- Allogeneic (Donor) Bone Marrow Transplant to Treat Breast Cancer
ClinicalTrials.gov Identifier: NCT00005568 - No longer recruiting
Breast Cancer; Breast Neoplasm
- MESNA for Prevention of Acute Deterioration of Renal Function Following Contrast Agent Application
ClinicalTrials.gov Identifier: NCT00223548 - Completed
Chronic Renal Insufficiency; Serum Creatinine Concentration; Contrast Media Exposition
- Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002565 - Completed
Lymphoma
- Stem Cell Transplant to Treat Patients with Systemic Sclerosis
ClinicalTrials.gov Identifier: NCT00058578 - Completed
Systemic Sclerosis
- High Dose Chemo/Radiotherapy and Hematopoietic Stem Cell Transplant for Patients with Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00040482 - Completed
Multiple Sclerosis
- Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
ClinicalTrials.gov Identifier: NCT00002875 - Completed
untreated childhood medulloblastoma
- Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients with Aplastic Anemia
ClinicalTrials.gov Identifier: NCT00004323 - Completed
Aplastic Anemia
- High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002865 - Completed
recurrent adult acute lymphocytic leukemia
- Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00002785 - Completed
untreated childhood acute lymphoblastic leukemia
- Chemotherapy Plus Radiation Therapy Followed by Surgery in Treating Patients With Soft Tissue Sarcoma
ClinicalTrials.gov Identifier: NCT00002791 - Completed
recurrent adult soft tissue sarcoma; stage II adult soft tissue sarcoma; stage III adult soft tissue sarcoma
- Combination Chemotherapy in Treating Pediatric Patients With Stage III or IV Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002691 - Completed
stage III childhood lymphoblastic lymphoma; stage III childhood large cell lymphoma; stage IV childhood large cell lymphoma; ...
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