Not Signed In -
Methotrexate |
Rheumatrex; Trexall |
Clinical Trial: Assessment of Rituximab''s Immunomodulatory Synovial Effects (The ARISE Study)
This study is currently recruiting patients.
Verified by University of California, San Diego September 2005
|
Purpose
Using repeated arthroscopic biopsies of patients with rheumatoid arthritis, we will assess changes in the immune response that occur as a result of treatment with rituximab.
| Condition | Intervention | Phase |
|---|---|---|
| Rheumatoid Arthritis active disease despite concomitant methotrexate | Drug: arthroscopic biopsy | Phase II |
MedlinePlus related topics: Rheumatoid Arthritis
Study Type: Interventional
Study Design: Diagnostic, Non-Randomized, Open Label, Active Control, Single Group Assignment, Safety/Efficacy Study
Official Title: Assessment of the Immunomodulatory Effects of Rituximab in Seropositive Rheumatoid Arthritis Using Arthroscopic Synovial Biopsies
Eligibility
Ages Eligible for Study: 18 Years - 75 Years, Genders Eligible for Study: Both
Criteria
Inclusion Criteria:
- Active rheumatoid arthritis use of concomitant methotrexate
Exclusion Criteria:
- Use of DMARDs/biologics other than methotrexate serious medical conditions that would preclude the use of the treating agent
Location and Contact Information
Please refer to this study by ClinicalTrials.gov identifier NCT00147966
Arthur Kavanaugh, MD 858-657-7040 akavanaugh@ucsd.edu
California
UCSD CIT, La Jolla, California, 92093, United States; Recruiting
Jessica Hallinan 858-657-7042 jhallinan@ucsd.edu
Study chairs or principal investigators
Arthur Kavanaugh, MD, Principal Investigator, UCSD CIT
More Information
Study ID Numbers: 041569
Last Updated: September 6, 2005
Record first received: September 2, 2005
ClinicalTrials.gov Identifier: NCT00147966
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-09-13
Last Updated: September 6, 2005
Record first received: September 2, 2005
ClinicalTrials.gov Identifier: NCT00147966
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-09-13
Resources
- Methotrexate (Drug Digest)
- Methotrexate (Cleveland Clinic)
email this page
print this page
bookmark this page
feedback on this page
