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Metronidazole Topical |
MetroCream; MetroGel; MetroLotion; Noritate Topical |
Metronidazole Systematic (IUPAC) name 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol Identifiers CAS number 443-48-1 ATC code J01XD01 PubChem 4173 DrugBank APRD00631 Chemical data Formula C6H9N3O3 Mol. weight 171.15 g/mol Pharmacokinetic data Bioavailability 100% (oral) 59–94% (rectal) Metabolism Hepatic Half life 6–7 hours Excretion Renal (60-80%), biliary (6–15%) Therapeutic considerations Pregnancy cat. B2 (Au) Legal status S4(AU) PO ...
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Metronidazole Topical Clinical Trials
- Evaluation of Topical 10% Metronidazole Ointment for the Treatment of Active Perianal Crohn's Disease
ClinicalTrials.gov Identifier: NCT00509639 - Recruiting
Crohn's Disease
- Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
ClinicalTrials.gov Identifier: NCT00066066 - Recruiting
Periodontitis; Periodontal Diseases
- Does Topical Steroid Treatment Impair the Adrenal Function?
ClinicalTrials.gov Identifier: NCT00476489 - Recruiting
Hypothalamus-Pituitary-Adrenal Axis Assessement; Topical Steroid Therapy in Chronic Skin Diseases
- Efficacy of Metronidazole Versus Metronidazole and Rifampin in CDAD Treatment
ClinicalTrials.gov Identifier: NCT00182429 - Completed
Clostridium Enterocolitis; Antibiotic-Associated Diarrhea; Pseudomembranous Colitis; Pseudomembranous Enterocolitis; Pseudomembranous Enteritis
- Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes
ClinicalTrials.gov Identifier: NCT00567528 - Recruiting
Soft Tissue Injuries; Comparison of Topical and Oral Ibuprofen
- Study to Compare the Acne Relapse Rate of Oral Minocycline to Oral Minocycline in Combination With Topical Tretinoin, Followed by Topical Tretinoin Alone
ClinicalTrials.gov Identifier: NCT00240513 - Recruiting
Acne Vulgaris
- Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-Abdominal Infection
ClinicalTrials.gov Identifier: NCT00195351 - Recruiting
Appendicitis; Cholecystitis; Cross Infection; Diverticulitis; Peritonitis
- Metronidazole for Pulmonary Tuberculosis (South Korea)
ClinicalTrials.gov Identifier: NCT00425113 - Recruiting
Tuberculosis; Multi-Drug Resistant Tuberculosis
- Response of Clostridium Difficile Infection to Metronidazole Therapy
ClinicalTrials.gov Identifier: NCT00304369 - Recruiting
Clostridium Enterocolitis; Pseudomembranous Colitis; Antibiotic-Associated Colitis
- Topical Amethocaine Gel for Intramuscular Injection in Term Neonates
ClinicalTrials.gov Identifier: NCT00267111 - Active, not recruiting
Pain
- An Imaging Trial of the Distribution of Topical Gel Formulations in the Human Vagina
ClinicalTrials.gov Identifier: NCT00214747 - Active, not recruiting
HIV Infections
- Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss
ClinicalTrials.gov Identifier: NCT00418730 - Active, not recruiting
Androgenetic Alopecia
- A Study to Determine the Optimal Tolerated Regime and Safety of PEP005 Topical Gel
ClinicalTrials.gov Identifier: NCT00427050 - Active, not recruiting
Actinic Keratoses
- Treating Periodontal Infection: Effects on Glycemic Control in People with Type 2 Diabetes
ClinicalTrials.gov Identifier: NCT00016835 - Active, not recruiting
Periodontal Disease; Diabetes Mellitus, Non-Insulin-Dependent
- A Trial Comparing Moxifloxacin Versus Levofloxacin Plus Metronidazole In Uncomplicated Pelvic Inflammatory Disease
ClinicalTrials.gov Identifier: NCT00453349 - Recruiting
Pelvic Inflammatory Disease
- A Phase 4 Trial Assessing CLOBEX Spray, 0.05% When Used as Monotherapy or as Add-on Therapy to Existing Systemic or Topical Anti-Psoriatic Agents.
ClinicalTrials.gov Identifier: NCT00437216 - Active, not recruiting
Psoriasis
- Ketoprofen Topical Patch, 20% in the Treatment of Pain Associated With Osteoarthritis Flare of the Knee
ClinicalTrials.gov Identifier: NCT00365586 - Active, not recruiting
Osteoarthritis
- Microbial Associations in Periodontal Health and Disease
ClinicalTrials.gov Identifier: NCT00066001 - Recruiting
Periodontitis; Periodontal Diseases
- Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail
ClinicalTrials.gov Identifier: NCT00443820 - Active, not recruiting
Onychomycosis
- Efficacy, Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail
ClinicalTrials.gov Identifier: NCT00443898 - Active, not recruiting
Onychomycosis
- Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
ClinicalTrials.gov Identifier: NCT00002682 - Active, not recruiting
mucosa-associated lymphoid tissue; stage I diffuse small lymphocytic/marginal zone lymphoma
- Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-Abdominal Infection (cIAI)
ClinicalTrials.gov Identifier: NCT00230971 - Recruiting
Appendicitis; Cholecystitis; Diverticulitis; Intra-Abdominal Abscess; Intra-Abdominal Infection; Peritonitis
- Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants
ClinicalTrials.gov Identifier: NCT00433485 - Active, not recruiting
Neoplastic Syndrome; Non-Melanomatous Skin Cancer
- A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand
ClinicalTrials.gov Identifier: NCT00544297 - Active, not recruiting
Actinic Keratosis
- Safety and Efficacy Trial of the Use of A-007 Topical Gel in the Treatment of HSIL of the Cervix
ClinicalTrials.gov Identifier: NCT00285207 - Active, not recruiting
Cervical Intraepithelial Neoplasia; Uterine Cervical Dysplasia
- Topical Sunscreen in Preventing Skin Rash in Patients Receiving Drugs Such as Erlotinib or Cetuximab for Cancer
ClinicalTrials.gov Identifier: NCT00362986 - Active, not recruiting
Dermatologic Complications; Unspecified Adult Solid Tumor, Protocol Specific
- Study of Antibiotics in the Treatment of Colonic Crohn''s Disease
ClinicalTrials.gov Identifier: NCT00257699 - Recruiting
Crohn''s Disease
- Efficacy, Safety and Tolerability of Topical 10% Terbinafine Hydrogen Chloride Versus 5% Amorolfine Nail Lacquer in Patients With Mild to Moderate Toenail Onychomycosis
ClinicalTrials.gov Identifier: NCT00459537 - Active, not recruiting
Onychomycosis
- Efficacy of a New Topical Anesthetic
ClinicalTrials.gov Identifier: NCT00562211 - Recruiting
Pain
- Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain
ClinicalTrials.gov Identifier: NCT00351104 - Active, not recruiting
Sprain; Strain
- Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis
ClinicalTrials.gov Identifier: NCT00352625 - Active, not recruiting
Tendonitis; Bursitis
- Topical Tacrolimus 0.03% Ointment for Intractable Allergic Conjunctivitis: An Open Label Pilot Study
ClinicalTrials.gov Identifier: NCT00443105 - Active, not recruiting
Allergic Conjunctivitis
- A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris
ClinicalTrials.gov Identifier: NCT00421993 - Active, not recruiting
Acne Vulgaris
- Efficacy and Safety of Topical Bromfenac Ophthalmic Solution vs. Placebo in Subjects With Allergic Conjunctivitis
ClinicalTrials.gov Identifier: NCT00423007 - Active, not recruiting
Allergic Conjunctivitis
- Study of a New Dressing for Use With Topical Medications
ClinicalTrials.gov Identifier: NCT00234728 - Recruiting
Psoriasis
- Topical Agent for Treatment of Red Skin
ClinicalTrials.gov Identifier: NCT00279890 - Active, not recruiting
Rosacea; Bilaterally Symmetric Red Skin on Cheeks
- Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora
ClinicalTrials.gov Identifier: NCT00312338 - Active, not recruiting
Bacterial Conjunctivitis
- A Study of the Effect of Time on Topical Anesthetic Efficacy.
ClinicalTrials.gov Identifier: NCT00353041 - Recruiting
Pain
- New Topical Treatment for Continued Pain After Shingles
ClinicalTrials.gov Identifier: NCT00566904 - Recruiting
Postherpetic Neuralgia
- Evaluation of Topical B12 for the Treatment of Childhood Atopic Dermatitis
ClinicalTrials.gov Identifier: NCT00465699 - Recruiting
Eczema
- A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers
ClinicalTrials.gov Identifier: NCT00351767 - Active, not recruiting
Diabetic Foot Ulcers
- Topical Imiquimod in Treating Patients With Recurrent Paget's Disease of the Vulva
ClinicalTrials.gov Identifier: NCT00504023 - Recruiting
Vulvar Cancer
- Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma
ClinicalTrials.gov Identifier: NCT00003151 - Active, not recruiting
contiguous stage II diffuse small lymphocytic/marginal zone lymphoma; stage I diffuse small lymphocytic/marginal zone lymphoma
- The Purpose of This Study is to Determine Whether Topical Application of PEP005 is Safe for the Treatment of Common Wart(s)
ClinicalTrials.gov Identifier: NCT00546611 - Recruiting
Warts
- An Imaging Trial of the Distribution of Topical Gel in the Human Vagina: Assessment of Bare Spots
ClinicalTrials.gov Identifier: NCT00214812 - Recruiting
HIV Infections
- Photodynamic Therapy Using Topical Aminolevulinic Acid in Treating Patients With Actinic Keratosis
ClinicalTrials.gov Identifier: NCT00524485 - Recruiting
Precancerous/Nonmalignant Condition
- Dose-Ranging Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss
ClinicalTrials.gov Identifier: NCT00471510 - Recruiting
Androgenetic Alopecia
- A Prospective Study of the Effect of Topical Sodium Hyaluronate Immediately Post-PKP on Time to Reepithelialization
ClinicalTrials.gov Identifier: NCT00570648 - Recruiting
Corneal Transplantation
- Ocular Hypertension Treatment Study (OHTS)
ClinicalTrials.gov Identifier: NCT00000125 - Active, not recruiting
Ocular Hypertension; Glaucoma
- Analgesia and Wound Healing Assessment Following Topical Morphine Applied to Patients With Cutaneous Cancer Related Pain
ClinicalTrials.gov Identifier: NCT00306020 - Recruiting
Ulcer; Wounds and Injuries
- To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC
ClinicalTrials.gov Identifier: NCT00432185 - Recruiting
Superficial Basal Cell Carcinoma
- The Sun Protection Effect and Efficacy in Treatment of Sunburn Using Topical Corticosteroids.
ClinicalTrials.gov Identifier: NCT00206882 - Recruiting
Sunburn
- Efficacy and Tolerability Study of Topical Ciclosporin in a Psoriasis Plaque Test
ClinicalTrials.gov Identifier: NCT00578370 - Recruiting
Psoriasis
- Optimizing Hepatitis B Vaccine Response Through the Use of a Topical Immune Modulator
ClinicalTrials.gov Identifier: NCT00175435 - Recruiting
Hepatitis B
- Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test
ClinicalTrials.gov Identifier: NCT00236171 - Recruiting
Psoriasis Vulgaris
- Topical PH-10 Aqueous Hydrogel and Photodynamic Therapy for Psoriasis
ClinicalTrials.gov Identifier: NCT00555646 - Recruiting
Plaque Psoriasis
- Topical 5-ALA Photodynamic Therapy for the Treatment of Verruca Vulgaris
ClinicalTrials.gov Identifier: NCT00155584 - Recruiting
Warts
- Bicillin L-A vs Placebo for the Treatment of Chronic, Plaque-Type Psoriasis Unresponsive to Topical Medications
ClinicalTrials.gov Identifier: NCT00427609 - Recruiting
Psoriasis
- Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis of the Knee: Trial I
ClinicalTrials.gov Identifier: NCT00546507 - Recruiting
Osteoarthritis
- Corneal Thinning During Topical Bevacizumab Therapy
ClinicalTrials.gov Identifier: NCT00515684 - Recruiting
Corneal Neovascularization
- Dermal Substitute and Topical Negative Pressure in Burns
ClinicalTrials.gov Identifier: NCT00548314 - Recruiting
Burns
- Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children
ClinicalTrials.gov Identifier: NCT00521703 - Recruiting
Dyspepsia; Malabsorption Syndrome; Gastroesophageal Reflux Disease; Abdominal Pain
- Immunogenicity and Safety Study of Topical Recombinant Thrombin in Surgical Hemostasis
ClinicalTrials.gov Identifier: NCT00491608 - Recruiting
Spine Surgery; Vascular Surgery
- Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis of the Knee: Trial II
ClinicalTrials.gov Identifier: NCT00546832 - Recruiting
Osteoarthritis
- Efficacy and Safety of Topical Versus Systemic Treatment in Postherpetic Neuralgia and Diabetic Polyneuropathic Pain
ClinicalTrials.gov Identifier: NCT00414349 - Recruiting
Neuropathic Pain
- Efficacy of Topical Cyclosporin for Ocular Rosacea
ClinicalTrials.gov Identifier: NCT00348335 - Recruiting
Rosacea
- Comparison Study of Topical Acne Regimens
ClinicalTrials.gov Identifier: NCT00419523 - Recruiting
Acne
- Effectiveness of Topical Thalidomide to Treat Chronic Graft-Versus-Host-Disease Related Stomatitis
ClinicalTrials.gov Identifier: NCT00075023 - Recruiting
- Study Mild Intermittent Asthma to Assess the Topical Safety and Tolerability of Albuterol Sulfate Acu-30™ DPI
ClinicalTrials.gov Identifier: NCT00565591 - Recruiting
Allergic Asthma
- Determine the efficacy of topical tretinoin cream for the prevention of nonmelanoma skin cancer
ClinicalTrials.gov Identifier: NCT00007631 - Active, not recruiting
nonmelanoma skin cancer
- Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts
ClinicalTrials.gov Identifier: NCT00499967 - Recruiting
Genital Warts
- PK and PD of Calcitriol BID Topical Treatment in Adolescents With Plaque Psoriasis
ClinicalTrials.gov Identifier: NCT00419666 - Recruiting
Chronic Plaque Psoriasis
- Topical Romidepsin in Treating Patients With Stage I or Stage II Cutaneous T-Cell Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00477698 - Recruiting
Lymphoma
- Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis
ClinicalTrials.gov Identifier: NCT00426985 - Recruiting
Tendonitis; Bursitis
- To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions
ClinicalTrials.gov Identifier: NCT00493064 - Recruiting
Retinal Vein Occlusion
- A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)
ClinicalTrials.gov Identifier: NCT00576108 - Recruiting
Postherpetic Neuralgia; Shingles; Herpes Zoster; Neuropathic Pain
- Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation
ClinicalTrials.gov Identifier: NCT00556478 - Recruiting
Premature Ejaculation
- Helicobacter - Lymphoma - Radiation Part I: Eradication, Part II: Radiation
ClinicalTrials.gov Identifier: NCT00154440 - Recruiting
Lymphoma, Mucosa-Associated Lymphoid Tissue; B-cell Non-Hodgkin''y Lymphoma of the stomach, primary gastric
- A Comparison of EpiCept™ NP-1 Topical Cream vs. Oral Gabapentin in Postherpetic Neuralgia (PHN)
ClinicalTrials.gov Identifier: NCT00475904 - Recruiting
Post Herpetic Neuralgia; PHN; Neuropathy; Nerve Pain
- Pilot Study of the Safety and Clinical Efficacy of Topical Dermacyn™ Wound Care to Treat Mild Diabetic Foot Infections
ClinicalTrials.gov Identifier: NCT00516958 - Recruiting
Foot Ulcer, Diabetic
- Effectiveness and Safety of Topical Bevacizumab (Avastin) for Treatment of Corneal Neovascularization
ClinicalTrials.gov Identifier: NCT00512876 - Recruiting
Corneal Neovascularization
- Adalimumab in Combination With Topical Treatment (Calcipotriol/Betamethasone) in Subjects With Moderate to Severe Psoriasis and Insufficient Response to Classic Systemic Treatment
ClinicalTrials.gov Identifier: NCT00574249 - Recruiting
Chronic Plaque Psoriasis
- Topical Imiquimod Compared With Surgery in Treating Patients With Basal Cell Skin Cancer
ClinicalTrials.gov Identifier: NCT00066872 - Active, not recruiting
basal cell carcinoma of the skin
- Efficacy Study of Topical Application of Nifedipine Cream to Treat Vulvar Vestibulitis
ClinicalTrials.gov Identifier: NCT00496184 - Recruiting
Vulvar Diseases; Vulvar Pain; Vestibulitis; Vestibulodynia; Vulvodynia
- Mechanisms of Skin Repair by Topical Estrogen
ClinicalTrials.gov Identifier: NCT00113100 - Completed
Skin Wrinkling
- Topical Halofuginone Hydrobromide in Treating Patients With HIV-Related Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00064142 - Active, not recruiting
epidemic Kaposi's sarcoma; recurrent Kaposi's sarcoma
- A Phase 3 Study to Compare the Safety and Efficacy of 5% Dapsone Topical Gel, (DTG) Twice Daily in Combination with Once Daily Vehicle Control, Adapalene Gel 0.1% or Benzoyl Peroxide Gel 4%.
ClinicalTrials.gov Identifier: NCT00151541 - Completed
Acne Vulgaris
- The Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent GVHD Related Dry Eye
ClinicalTrials.gov Identifier: NCT00553735 - Recruiting
Graft Versus Host Disease Related Dry Eye
- A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy
ClinicalTrials.gov Identifier: NCT00476151 - Recruiting
Diabetic Peripheral Neuropathy; Neuralgia
- Topical Cyclosporine and Disease Progression
ClinicalTrials.gov Identifier: NCT00567983 - Recruiting
Disease Progression; Disease Severity; Staining; Schirmers; OSDI
- Topical Steroid Treatment for Eosinophilic Esophagitis
ClinicalTrials.gov Identifier: NCT00275561 - Recruiting
Eosinophilic Esophagitis
- Topical Avastin for Treatment of Corneal Neovascularization
ClinicalTrials.gov Identifier: NCT00559936 - Recruiting
Corneal Neovascularization
- Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer
ClinicalTrials.gov Identifier: NCT00296036 - Recruiting
Breast Cancer; Drug Toxicity; Unspecified Adult Solid Tumor, Protocol Specific
- Evaluation of Adherence to Topical Agents: Applying Communication Technology to Improve Sunscreen Use
ClinicalTrials.gov Identifier: NCT00535769 - Not yet recruiting
Skin Cancer
- 62% & 15% Ethanol in Emollient Gel as Topical Male Microbicides
ClinicalTrials.gov Identifier: NCT00469547 - Not yet recruiting
Sexually Transmitted Infection
- Study of the Safety and Acceptability of UC-781 Vaginal Microbicide
ClinicalTrials.gov Identifier: NCT00132444 - Recruiting
HIV
- Topical Ocular Mecamylamine in Diabetic Macular Edema (DME)
ClinicalTrials.gov Identifier: NCT00536692 - Recruiting
Diabetic Macular Edema
- Topical Antibiotics and Intravitreous Injections
ClinicalTrials.gov Identifier: NCT00410891 - Recruiting
Intravitreous; Injections
- Evaluation of Topical Mitomycin C as Adjuvant Drug to Esophageal Dilation in Children
ClinicalTrials.gov Identifier: NCT00551824 - Recruiting
Esophageal Stricture; Caustic Esophageal Stricture; Peptic Esophageal Stricture; Post-Surgical Esophageal Stricture
- Effects of Common Topical Glaucoma Therapy on Optic Nerve Head Blood Flow Autoregulation During Increased Arterial Blood Pressure and Artificially Elevated Intraocular Pressure in Healthy Humans
ClinicalTrials.gov Identifier: NCT00275756 - Recruiting
Glaucoma; Ocular Physiology; Regional Blood Flow
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