Mitoxantrone |
Novantrone |
Mitoxantrone Systematic (IUPAC) name 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino) ethylamino]-anthracene-9,10-dione Identifiers CAS number 65271-80-9 ATC code L01DB07 PubChem 4212 DrugBank APRD00371 Chemical data Formula C22H28N4O6 Mol. weight 444.481 g/mol Pharmacokinetic data Bioavailability ? Protein binding 78% Metabolism Hepatic (CYP2E1) Half life 75 hours Excretion Urinary Therapeutic considerations Pregnancy cat. D (United State ...
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Mitoxantrone Clinical Trials
- Phase I Study of Weekly Intravenous PS-341 Plus Mitoxantrone
ClinicalTrials.gov Identifier: NCT00059631 - Active, not recruiting
Prostate Cancer
- Combination Chemotherapy Compared With Mitoxantrone in Treating Older Patients With Advanced Breast Cancer
ClinicalTrials.gov Identifier: NCT00002498 - Active, not recruiting
stage IV breast cancer; recurrent breast cancer
- Mitoxantrone With or Without Docetaxel in Treating Women With Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00002544 - Active, not recruiting
stage IV breast cancer; recurrent breast cancer
- Bortezomib and Mitoxantrone in Treating Patients With Advanced or Metastatic Androgen-Independent Prostate Cancer
ClinicalTrials.gov Identifier: NCT00082680 - Active, not recruiting
recurrent prostate cancer; stage III prostate cancer; stage IV prostate cancer
- Mitoxantrone and G-CSF in Treating Patients With Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00003183 - Active, not recruiting
stage IV prostate cancer; adenocarcinoma of the prostate; recurrent prostate cancer
- Mitomycin and Mitoxantrone in Treating Patients With Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00003003 - Active, not recruiting
recurrent adult acute myeloid leukemia; secondary acute myeloid leukemia
- Efficacy and Safety Study of Oral Fludarabine Phosphate in Combination With Mitoxantrone as First Line Treatment in Follicular NHL
ClinicalTrials.gov Identifier: NCT00185445 - Active, not recruiting
Non Hodgkin Lymphoma
- Hormone Therapy With or Without Mitoxantrone and Prednisone in Treating Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer
ClinicalTrials.gov Identifier: NCT00004124 - Active, not recruiting
adenocarcinoma of the prostate; stage I prostate cancer; stage II prostate cancer; stage III prostate cancer; stage IV prostate cancer; ...
- Mitoxantrone Following Surgery in Treating Patients With Prostate Cancer at High Risk for Recurrence
ClinicalTrials.gov Identifier: NCT00003858 - Active, not recruiting
stage III prostate cancer; stage II prostate cancer; adenocarcinoma of the prostate; stage IV prostate cancer; stage I prostate cancer
- Fludarabine, Mitoxantrone, and Dexamethasone (FND) Plus Rituximab for Lymphoma Patients
ClinicalTrials.gov Identifier: NCT00577993 - Active, not recruiting
Lymphoma
- Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers
ClinicalTrials.gov Identifier: NCT00015951 - Active, not recruiting
recurrent adult acute myeloid leukemia; relapsing chronic myelogenous leukemia; blastic phase chronic myelogenous leukemia; ...
- Combination Chemotherapy in Treating Older Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002576 - Active, not recruiting
Lymphoma
- Calcitriol, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00182741 - Active, not recruiting
Prostate Cancer
- Phase II Study of Fludarabine and Mitoxantrone, Followed by GM-CSF and Rituximab
ClinicalTrials.gov Identifier: NCT00208975 - Recruiting
Lymphoma
- Trial of GM-CSF Given in Combination With Ketoconazole and Mitoxantrone in Patients With Progressive Prostate Cancer
ClinicalTrials.gov Identifier: NCT00447473 - Recruiting
Prostatic Neoplasms
- Cyclosporine and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002688 - Active, not recruiting
Leukemia, Myeloid
- Vaccine Therapy Plus Sargramostim Following Chemotherapy in Treating Patients With Previously Untreated Aggressive Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00004197 - Active, not recruiting
Lymphoma
- Gemcitabine and Mitoxantrone in Treating Patients With Relapsed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00268242 - Recruiting
Adult Acute Erythroid Leukemia; Adult Acute Monoblastic and Acute Monocytic Leukemia; Adult Acute Myeloid Leukemia
- Bendamustine and Mitoxantrone in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00274963 - Recruiting
Leukemia
- Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Relapsed or Refractory Acute Leukemia
ClinicalTrials.gov Identifier: NCT00470197 - Recruiting
Leukemia
- Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00407966 - Recruiting
Leukemia
- Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer
ClinicalTrials.gov Identifier: NCT00546377 - Recruiting
Leukemia; Lymphoma
- Chemotherapy in Treating Patients Who Have Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00003343 - Active, not recruiting
stage IV prostate cancer
- Gemtuzumab Ozogamicin in Combination with A-HAM in Refractory AML (GO-A-HAM)
ClinicalTrials.gov Identifier: NCT00143975 - Active, not recruiting
Leukemia, Myeloid, Acute
- Combination Chemotherapy in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002905 - Active, not recruiting
AIDS-related peripheral/systemic lymphoma
- Ixabepilone, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy and Chemotherapy
ClinicalTrials.gov Identifier: NCT00331344 - Recruiting
Prostate Cancer
- XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer (TROPIC)
ClinicalTrials.gov Identifier: NCT00417079 - Recruiting
Neoplasms; Prostatic Neoplasms
- Therapy of Acute Myeloid Leukemia in Patients Over the Age of 60 : DA Versus Mitoxantrone With Intermittent AraC
ClinicalTrials.gov Identifier: NCT00180167 - Recruiting
Leukemia, Nonlymphocytic, Acute
- Chemotherapy Followed by Zevalin for Relapsed Mantle Cell Lymphoma
ClinicalTrials.gov Identifier: NCT00119730 - Active, not recruiting
Mantle Cell Lymphoma
- Study of VELCADE® With Mitoxantrone and Etoposide for Leukemias
ClinicalTrials.gov Identifier: NCT00410423 - Recruiting
Relapsed Acute Leukemia; Refractory Acute Leukemia
- Phase II GM-CSF Plus Mitoxantrone in Hormone Refractory Prostate Cancer
ClinicalTrials.gov Identifier: NCT00477087 - Recruiting
Prostate Cancer
- High Dose Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Therapy in Treating Women With Metastatic or Recurrent Breast Cancer
ClinicalTrials.gov Identifier: NCT00003032 - Active, not recruiting
stage IV breast cancer; recurrent breast cancer
- Combination Chemotherapy Plus Filgrastim in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00032149 - Active, not recruiting
AIDS-Related Lymphoma
- Vinblastine, Cyclophosphamide, Procarbazine, Prednisolone, Etoposide, Mitoxantrone, and Bleomycin in Treating Older Patients With Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00079105 - Recruiting
stage I adult Hodgkin's lymphoma; stage II adult Hodgkin's lymphoma; stage III adult Hodgkin's lymphoma; stage IV adult Hodgkin's lymphoma
- Combination Chemotherapy in Treating Older Women With Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00010075 - Active, not recruiting
stage IV breast cancer; recurrent breast cancer
- Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer
ClinicalTrials.gov Identifier: NCT00003893 - Active, not recruiting
stage I breast cancer
- Combination Chemotherapy in Treating Pain in Patients With Hormone Refractory Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00003232 - Active, not recruiting
Pain; adenocarcinoma of the prostate; recurrent prostate cancer; Quality of Life
- Study of Rebif® Compared With no Treatment in the Therapy of Relapsing Multiple Sclerosis After Mitoxantrone
ClinicalTrials.gov Identifier: NCT00283140 - Recruiting
Relapsing Remitting Multiple Sclerosis
- Combination Chemotherapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
ClinicalTrials.gov Identifier: NCT00006114 - Active, not recruiting
adenocarcinoma of the prostate; stage IV prostate cancer; recurrent prostate cancer
- Combination Chemotherapy in Treating Patients With Lymphoma
ClinicalTrials.gov Identifier: NCT00002835 - Active, not recruiting
Lymphoma
- Phase II Study of Irofulven in Patients with Hormone-Refractory Prostate Cancer
ClinicalTrials.gov Identifier: NCT00124566 - Active, not recruiting
Prostate Cancer
- Combination Therapy With Fludarabine, Mitoxantrone and Rituximab in Mantle Cell Lymphoma
ClinicalTrials.gov Identifier: NCT00183989 - Recruiting
Mantle Cell Lymphoma
- Study of Liposome Encapsulated Mitoxantrone (LEM) in Patients with Advanced Cancer
ClinicalTrials.gov Identifier: NCT00024492 - Completed
Tumors
- Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
ClinicalTrials.gov Identifier: NCT00003633 - Active, not recruiting
adenocarcinoma of the prostate; stage IV prostate cancer; recurrent prostate cancer
- Comparison of Three Combination Chemotherapy Regimens in Treating Women With Stage I or Stage II Breast Cancer
ClinicalTrials.gov Identifier: NCT00004237 - Active, not recruiting
stage I breast cancer; stage II breast cancer
- A Phase I/II Study of AMD3100 With Mitoxantrone, Etoposide and Cytarabine (AMD3100+MEC) in Relapsed or Refractory AML
ClinicalTrials.gov Identifier: NCT00512252 - Recruiting
Relapsed or Refractory AML
- Combination Therapy in Treating Patients With Advanced Prostate Cancer That Have Not Responded to Hormone Therapy
ClinicalTrials.gov Identifier: NCT00004001 - Active, not recruiting
adenocarcinoma of the prostate; stage IV prostate cancer; recurrent prostate cancer
- Mitoxantrone, Prednisone Plus Sorafenib in Taxane-Refractory Metastatic Hormone Refractory Prostate Cancer (HRPC)
ClinicalTrials.gov Identifier: NCT00452387 - Recruiting
Metastatic Prostate Cancer
- Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002531 - Active, not recruiting
non-T, non-B adult acute lymphoblastic leukemia; untreated adult acute lymphoblastic leukemia; B-cell adult acute lymphoblastic leukemia; ...
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002517 - Active, not recruiting
Myeloid Leukemia; Myelodysplastic Syndromes; Refractory Anemia
- Chemotherapy With or Without Biological Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
ClinicalTrials.gov Identifier: NCT00005847 - Active, not recruiting
adenocarcinoma of the prostate; stage IV prostate cancer; recurrent prostate cancer
- Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002674 - Active, not recruiting
accelerated phase chronic myelogenous leukemia; Philadelphia chromosome positive chronic myelogenous leukemia; ...
- Combination Chemotherapy Followed by Surgery in Treating Patients With Localized Prostate Cancer
ClinicalTrials.gov Identifier: NCT00017563 - Active, not recruiting
adenocarcinoma of the prostate; stage II prostate cancer; stage III prostate cancer
- High-Dose Chemotherapy and Autologous Blood Cell Transplantation in Treating Patients With Primary, Locally Advanced, or Stage IV Breast Cancer
ClinicalTrials.gov Identifier: NCT00003068 - Active, not recruiting
stage IIIB breast cancer; Drug Toxicity; stage IIIA breast cancer; stage IV breast cancer; recurrent breast cancer
- Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003650 - Active, not recruiting
stage I childhood lymphoblastic lymphoma; stage II childhood lymphoblastic lymphoma; stage III childhood lymphoblastic lymphoma; ...
- Filgrastim and Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Hodgkin's Lymphoma or Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00005985 - Active, not recruiting
Hodgkin's lymphoma; adult T-cell leukemia and lymphoma; Non-Hodgkin's Lymphoma
- Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00005823 - Active, not recruiting
Acute Myeloid Leukemia; adult acute monoblastic and acute monocytic leukemia; atypical chronic myeloid leukemia; Chronic Myelomonocytic Leukemia; ...
- Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002658 - Active, not recruiting
Myeloid Leukemia; Neutropenia
- Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma
ClinicalTrials.gov Identifier: NCT00002766 - Active, not recruiting
Philadelphia chromosome positive chronic myelogenous leukemia; adult acute lymphoblastic leukemia; adult lymphoblastic lymphoma; ...
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Cancer
ClinicalTrials.gov Identifier: NCT00003297 - Active, not recruiting
recurrent ovarian epithelial cancer; stage III ovarian epithelial cancer; stage IV ovarian epithelial cancer
- Peripheral Stem Cell Transplantation With Specially Treated Stem Cells in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00005998 - Active, not recruiting
Hodgkin's Disease; Lymphocytic Lymphoma
- Chemotherapy With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00052299 - Active, not recruiting
adult acute monoblastic and acute monocytic leukemia; adult acute myeloid leukemia; secondary acute myeloid leukemia
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002701 - Active, not recruiting
untreated adult acute myeloid leukemia; adult acute promyelocytic leukemia (M3)
- Phase II Study of Novantrone(R) (Mitoxantrone) and Etoposide in Patients with HIV Associated Large Cell and Immunoblastic Lymphomas
ClinicalTrials.gov Identifier: NCT00002003 - Completed
Lymphoma, Non-Hodgkin; HIV Infections
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003957 - Active, not recruiting
recurrent grade III follicular large cell lymphoma; recurrent adult immunoblastic large cell lymphoma; recurrent adult diffuse mixed cell lymphoma; ...
- Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002549 - Active, not recruiting
adult acute myelomonocytic leukemia (M4); untreated adult acute myeloid leukemia; adult acute differentiated monocytic leukemia (M5b); ...
- Chemotherapy Followed by Donor White Blood Cells Plus Interleukin-2 in Treating Patients With Acute Myeloid or Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00005802 - Active, not recruiting
adult acute lymphoblastic leukemia; adult acute myeloid leukemia; childhood acute lymphoblastic leukemia; childhood acute myeloid leukemia
- Combination Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00003602 - Active, not recruiting
untreated adult acute myeloid leukemia; refractory anemia with excess blasts; refractory anemia with excess blasts in transformation; ...
- Gemtuzumab Ozogamicin With or Without Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00006122 - Active, not recruiting
untreated adult acute myeloid leukemia; adult acute differentiated monocytic leukemia (M5b); ...
- Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002719 - Active, not recruiting
adult acute myelomonocytic leukemia (M4); untreated adult acute myeloid leukemia; adult acute differentiated monocytic leukemia (M5b); ...
- Combination Chemotherapy Followed By Filgrastim or Sargramostim in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00053131 - Active, not recruiting
recurrent adult acute myeloid leukemia; recurrent childhood acute myeloid leukemia; recurrent adult acute lymphoblastic leukemia; ...
- Amifostine and High-Dose Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00003407 - Active, not recruiting
untreated adult acute myeloid leukemia; Drug Toxicity; secondary myelodysplastic syndrome; recurrent adult acute myeloid leukemia; ...
- Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00006045 - Active, not recruiting
adult acute differentiated monocytic leukemia (M5b); adult acute myeloblastic leukemia without maturation (M1); ...
- Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00006250 - Active, not recruiting
stage III grade 1 follicular lymphoma; stage III grade 2 follicular lymphoma; stage III grade 3 follicular lymphoma; ...
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Aggressive Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003215 - Active, not recruiting
adult diffuse large cell lymphoma; adult diffuse mixed cell lymphoma; adult immunoblastic large cell lymphoma; anaplastic large cell lymphoma
- Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00002700 - Active, not recruiting
untreated adult acute lymphoblastic leukemia; stage I adult lymphoblastic lymphoma; stage III adult lymphoblastic lymphoma; ...
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00003436 - Active, not recruiting
refractory anemia with excess blasts in transformation; refractory anemia with excess blasts; childhood acute promyelocytic leukemia (M3); ...
- Cellular Adoptive Immunotherapy in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndromes That Relapsed After Donor Stem Cell Transplant
ClinicalTrials.gov Identifier: NCT00107354 - Active, not recruiting
adult acute lymphoblastic leukemia; adult acute myeloid leukemia; childhood acute lymphoblastic leukemia; ...
- Ixabepilone Compared With Mitoxantrone and Prednisone in Treating Patients With Refractory Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00058084 - Completed
adenocarcinoma of the prostate; recurrent prostate cancer; stage IV prostate cancer
- Randomized Phase Iii-Study On Valproic Acid In Combination With All-Trans Retinoic Acid, Standard Induction- And Consolidation Therapy In Older Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00151255 - Recruiting
Acute myeloid leukemia, age > 60 years
- Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00005613 - Active, not recruiting
recurrent diffuse small lymphocytic/marginal zone lymphoma; recurrent adult diffuse small cleaved cell lymphoma; ...
- Combination Chemotherapy Plus Biological Therapy in Treating Patients With Acute Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00003405 - Active, not recruiting
untreated adult acute myeloid leukemia; childhood acute megakaryocytic leukemia (M7); adult acute differentiated monocytic leukemia (M5b); ...
- Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00109837 - Recruiting
L1 adult acute lymphoblastic leukemia; L2 adult acute lymphoblastic leukemia; untreated adult acute lymphoblastic leukemia
- Pixantrone or Other Chemotherapy Drugs in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00101049 - Recruiting
adult diffuse large cell lymphoma; adult diffuse mixed cell lymphoma; adult immunoblastic large cell lymphoma; anaplastic large cell lymphoma; ...
- Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003728 - Recruiting
acute undifferentiated leukemia; childhood acute lymphoblastic leukemia; childhood lymphoblastic lymphoma
- Mitoxantrone and Prednisone With or Without Leflunomide in Treating Patients With Stage IV Prostate Cancer
ClinicalTrials.gov Identifier: NCT00004071 - Completed
stage IV prostate cancer; recurrent prostate cancer; Quality of Life
- Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia
ClinicalTrials.gov Identifier: NCT00016016 - Completed
adult acute lymphoblastic leukemia; adult acute myeloid leukemia; secondary acute myeloid leukemia
- Registry to Evaluate Novantrone (R) Effects in Worsening Multiple Sclerosis (RENEW)
ClinicalTrials.gov Identifier: NCT00016614 - No longer recruiting
Multiple Sclerosis
- Estramustine, Docetaxel, and Carboplatin for Patients With Hormone Refractory Prostate Cancer Progressing After Mitoxantrone-Based Chemotherapy.
ClinicalTrials.gov Identifier: NCT00183924 - Completed
Prostate Adenocarcinoma
- Fludarabine, Mitoxantrone and Rituximab in Relapsed or Primary Failing Advanced Follicular Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00169208 - Completed
Follicular Lymphoma
- Study Evaluating Mitoxantrone in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00146159 - Terminated
Secondary Progressive Multiple Sclerosis
- Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00002565 - Completed
Lymphoma
- A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease)
ClinicalTrials.gov Identifier: NCT00304291 - Completed
Neuromyelitis Optica; Myelitis, Transverse; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System
- A Study to Evaluate the Safety and Effectiveness of Novantrone Therapy Followed by Copaxone Treatment for Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00203086 - Completed
Relapse Remitting Multiple Sclerosis
- Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00002259 - Completed
Sarcoma, Kaposi; HIV Infections
- Phase 2 Study of the Activity and Safety of Fludarabine, Cyclophosphamide, and Mitoxantrone Plus Rituximab (FCM-R) With Pegfilgrastim (Neulasta) as Frontline Therapy for Patients < 70 Years With Chronic Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00254410 - Suspended
Chronic Lymphocytic Leukemia
- Combination Chemotherapy and Bone Marrow Transplantation in Treating Patients With Refractory or Recurrent Ovarian Cancer
ClinicalTrials.gov Identifier: NCT00002474 - Completed
recurrent ovarian epithelial cancer
- Combination Chemotherapy in Treating Patients With Recurrent or Refractory Leukemia or Lymphoma
ClinicalTrials.gov Identifier: NCT00047021 - Completed
childhood Hodgkin's lymphoma; childhood non-Hodgkin's lymphoma; Leukemia; Lymphoma; myelodysplastic and myeloproliferative diseases
- Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Persistent or Platinum Refractory Stage III or IV Ovarian Cancer
ClinicalTrials.gov Identifier: NCT00003080 - Completed
stage III ovarian epithelial cancer; stage IV ovarian epithelial cancer; recurrent ovarian epithelial cancer
- Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002805 - Completed
recurrent childhood acute myeloid leukemia; secondary acute myeloid leukemia; Previously Treated Myelodysplastic Syndrome

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