Inclusion criteria

1. Received kidney transplant;
2. Receiving immunosuppressive regimen that includes MMF;
3. Patients with GI side effects on standard MMF doses or patients on reduced dose MMF with existing but tolerated/controlled GI side effects.
4. At least 18 years of age;
5. Willing to provide written informed consent; and
6. Able to meet all study requirements including completing questionnaires and completing four study visits.

Exclusion criteria

1. Patients with GI symptoms assumed or known not to be caused by MPA therapy (e.g. oral bisphosphonate induced, infectious diarrhea);
2. Acute rejection < 1 week prior to study enrollment;
3. Woman of child-bearing potential who is planning to become pregnant or is pregnant and/or lactating who is unwilling to use effective means of contraception;
4. Presence of psychiatric illness (i.e., schizophrenia, major depression) that, in the opinion of the site investigator, would interfere with study requirements;
5. Undergoing acute medical intervention or hospitalization;
6. Any other medical condition that, in the opinion of the site investigator based on recall or chart review would interfere with completing the study, including but not limited to, visual problems or cognitive impairment.
7. Receiving any investigational drug or have received any investigational drug within 30 days prior to study enrollment.

Additional protocol-defined inclusion/exclusion criteria may apply.