The study's purpose is to improve alcoholism treatment by investigating the combined effectiveness of a psychotherapy (Coping Skills Training and Cue Exposure Treatment - CSTCET) with naltrexone in a randomized clinical trial. Individuals will receive 2 weeks of CSTCET or a control treatment as inpatients followed by 12 consecutive weeks of receiving either naltrexone or placebo as outpatients. Followups at 24, 48, and 72 weeks after treatment is completed.

Ages Eligible for Study:  18 Years   -   65 Years,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Meets criteria for alcohol dependence.

Exclusion Criteria:

• Current diagnosis of dependence on other substances except nicotine.
• A history of psychosis or current psychotic symptoms.
• Current suicidality, homocidality, or psychiatric symptoms that require additional medication.
• Current use of disulfiram (Antabuse).
• Evidence of significant cerebral, renal, thyroid, or cardiac disease.
• History of opioid abuse in the previous year.
• History of cirrhosis, hepatocellular disease, or elevated bilirubin.
• Females who are pregnant, nursing, or not using a reliable method of birth control.