Quetiapine |
Seroquel |
Quetiapine Systematic (IUPAC) name 2-(2-(4-dibenzo[b,f][1,4]thiazepine- 11-yl-1-piperazinyl)ethoxy)ethanol Identifiers CAS number 111974-69-7 ATC code N05AH04 PubChem 5002 DrugBank APRD00675 Chemical data Formula C21H25N3O2S Mol. weight 383.5099 Pharmacokinetic data Bioavailability 100% in 1.5hr Metabolism Hepatic Half life 6 hours Excretion Renal Therapeutic considerations Pregnancy cat. C Legal status Rx Only Routes Oral Quetiapine ...
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Quetiapine Clinical Trials
- Study Measuring Differences in Cognition Due to Sedative Effects of Risperidone and Quetiapine in Stable Bipolar I Outpatients
ClinicalTrials.gov Identifier: NCT00097032 - Active, not recruiting
Bipolar Disorder
- Combination of Paroxetine CR and Quetiapine for the Treatment of Refractory Generalized Anxiety Disorder
ClinicalTrials.gov Identifier: NCT00113295 - Active, not recruiting
Anxiety Disorder
- Interaction between Cocaine and Quetiapine - 1
ClinicalTrials.gov Identifier: NCT00087750 - Active, not recruiting
Cocaine-Related Disorders
- Quetiapine Treatment for Symptoms Associated with Borderline Personality Disorder
ClinicalTrials.gov Identifier: NCT00122070 - Recruiting
Borderline Personality Disorder
- Efficacy of Quetiapine in the Treatment of Patients with Schizophrenia and a Comorbid Substance Use Disorder.
ClinicalTrials.gov Identifier: NCT00156715 - Active, not recruiting
Schizophrenia; Dual Diagnosis; Schizoaffective Disorder; Psychotic Disorder; Substance Abuse; Alcohol Abuse
- Study of Efficacy and Safety of Seroquel (Quetiapine Fumarate) as Mono-Therapy for Acute Schizophrenic
ClinicalTrials.gov Identifier: NCT00428350 - Active, not recruiting
Schizophrenia
- Unraveling the Relation of Patient's Profile and Therapeutical Effects of Atypicals, Including Quetiapine Effect
ClinicalTrials.gov Identifier: NCT00534222 - Active, not recruiting
Mania; Schizophrenia
- New Antipsychotic Strategies: Quetiapine and Risperidone vs. Fluphenazine in Treatment Resistant Schizophrenia
ClinicalTrials.gov Identifier: NCT00161018 - Active, not recruiting
Schizophrenia
- Quetiapine and the Dopaminergic Epigenetic Control
ClinicalTrials.gov Identifier: NCT00370500 - Recruiting
Schizophrenia
- A Study of Relapse Prevention and the Effectiveness of Long-Acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schiozaffective Disorder
ClinicalTrials.gov Identifier: NCT00216476 - Active, not recruiting
Schizophrenia; Psychotic Disorders
- Compare the Effects of Bifeprunox and Quetiapine on Weight Changes in Stable Schizophrenic Patients
ClinicalTrials.gov Identifier: NCT00396214 - Recruiting
Schizophrenia
- An Open-Label Study of Quetiapine Added to Oros Methylphenidate in the Treatment of ADHD and Aggressive Behavior
ClinicalTrials.gov Identifier: NCT00198211 - Active, not recruiting
Attention-Deficit/Hyperactivity Disorder, Combined Type; Disruptive Behavior Disorder
- A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
ClinicalTrials.gov Identifier: NCT00457366 - Recruiting
Agitation
- Study Evaluating The Safety, Tolerability, And Efficacy Of Switching From Quetiapine To Ziprasidone
ClinicalTrials.gov Identifier: NCT00406315 - Recruiting
Schizophrenia or Schizoaffective Disorder
- Study of Quetiapine Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomanic Symptoms or Mild Manic Symptoms
ClinicalTrials.gov Identifier: NCT00277667 - Active, not recruiting
Bipolar Disorder
- Quetiapine for the Treatment of Insomnia in Alzheimer''s Disease
ClinicalTrials.gov Identifier: NCT00232570 - Not yet recruiting
Alzheimer''s Disease
- Efficacy and Safety of Quetiapine in Treating Affective Symptoms of Patients With First-Episode Psychosis-a Pilot Study
ClinicalTrials.gov Identifier: NCT00511277 - Recruiting
Schizophrenia
- Treatment and Outcome of Early Onset Bipolar Disorder
ClinicalTrials.gov Identifier: NCT00048802 - Active, not recruiting
Bipolar Disorder
- Naturalistic Study, Comparison of Divalproex ER and Quetiapine for Adults With Acute Mania or Mixed Episodes
ClinicalTrials.gov Identifier: NCT00397020 - Recruiting
Bipolar Disorder
- Quetiapine Fumarate (SEROQUEL) in the Treatment of Adolescent Patients With Schizophrenia and Bipolar I Disorder
ClinicalTrials.gov Identifier: NCT00227305 - Active, not recruiting
Schizophrenia; Bipolar I Disorder
- A Randomized, Double-Blind, Placebo-Controlled Add-On Trial Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
ClinicalTrials.gov Identifier: NCT00223249 - Active, not recruiting
Bipolar Disorder; Alcohol Abuse/Dependence
- A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-Release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder
ClinicalTrials.gov Identifier: NCT00309699 - Active, not recruiting
Bipolar Disorder; Mood Disorders
- Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD)
ClinicalTrials.gov Identifier: NCT00237393 - Recruiting
PTSD
- Quetiapine (Seroquel) Maintenance Treatment in Early Onset Bipolar Spectrum Disorders
ClinicalTrials.gov Identifier: NCT00252226 - Recruiting
Bipolar Disorder
- Quetiapine Augmentation for Treatment-Resistant PTSD
ClinicalTrials.gov Identifier: NCT00292370 - Recruiting
Stress Disorders, Post-Traumatic; Combat Disorders
- Comparison of Continuing Olanzapine to Switching to Quetiapine in Overweight or Obese Patients with Schizophrenia and Schizoaffective Disorder
ClinicalTrials.gov Identifier: NCT00090012 - Completed
Schizophrenia
- A Non-Interventional Naturalistic Project to Investigate the Effect of the Use of SMS Text Service on Treatment Adherence in Patients Treated With Seroquel® (Quetiapine)
ClinicalTrials.gov Identifier: NCT00533260 - Recruiting
Bipolar Disorder; Schizophrenia
- The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence
ClinicalTrials.gov Identifier: NCT00434876 - Recruiting
Alcoholism; Sleep Initiation and Maintenance Disorders
- Quetiapine Fumarate (SEROQUEL) and Placebo in the Treatment of Acutely Ill Patients with Schizophrenia
ClinicalTrials.gov Identifier: NCT00085891 - Completed
Schizophrenia
- Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Adolescent Patients with Schizophrenia
ClinicalTrials.gov Identifier: NCT00090324 - Completed
Schizophrenia
- Quetiapine Augmentation Versus Clomipramine Augmentation of SSRI for Obsessive-Compulsive Disorder Patients
ClinicalTrials.gov Identifier: NCT00564564 - Active, not recruiting
Obsessive Compulsive Disorder
- Quetiapine and Cognition
ClinicalTrials.gov Identifier: NCT00517387 - Not yet recruiting
Unipolar Depression
- BMI and Metabolic Changes Following Switch to Aripiprazole From Olanzapine, Risperidone and Quetiapine.
ClinicalTrials.gov Identifier: NCT00312598 - Recruiting
Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder; Mood Disorders With Psychotic Features
- Group Cognitive Behavioral Therapy (CBT I) Vs. Quetiapine for Residual Insomnia Impairing Recovery Among Elderly With Stable Major Affective Disorders
ClinicalTrials.gov Identifier: NCT00462618 - Recruiting
Insomnia
- Switching Medication to Treat Schizophrenia
ClinicalTrials.gov Identifier: NCT00044655 - Recruiting
Schizophrenia
- Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Children and Adolescent Patients with Bipolar I Mania
ClinicalTrials.gov Identifier: NCT00090311 - Completed
Bipolar Disorder
- Double-Blind Placebo-Controlled Trial of Quetiapine in Anorexia Nervosa
ClinicalTrials.gov Identifier: NCT00518973 - Recruiting
Anorexia Nervosa
- Quetiapine Decreases Smoking in Patients With Chronic Schizophrenia
ClinicalTrials.gov Identifier: NCT00231101 - Recruiting
Smoking Behavior in Schizophrenia
- Quetiapine Induced Neuroplasticity in Schizophrenic Patients: A Combined TMS and VBM Study
ClinicalTrials.gov Identifier: NCT00554658 - Not yet recruiting
Schizophrenia
- Efficacy Study of Quetiapine Plus Topiramate for Reducing Cannabis Consumption and Bipolar Mania
ClinicalTrials.gov Identifier: NCT00393978 - Recruiting
Bipolar Disorder; Cannabis-Related Disorder
- High Dose of Quetiapine in Treating Subjects With Treatment Refractory Schizophrenia or Schizoaffective Disorder
ClinicalTrials.gov Identifier: NCT00297947 - Recruiting
Schizophrenia; Schizoaffective Disorder
- Quetiapine Efficacy in Bipolar Depression Study
ClinicalTrials.gov Identifier: NCT00523601 - Recruiting
Bipolar Depression
- Quetiapine vs. Placebo in Alcohol Relapse Prevention - a Pilot Study
ClinicalTrials.gov Identifier: NCT00561587 - Recruiting
Alcohol Relaps Prevention; Alcoholism; Alcohol Drinking; Alcohol Consumption; Alcohol Abuse
- A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence
ClinicalTrials.gov Identifier: NCT00227123 - Recruiting
Bipolar Disorder; Cocaine Dependence; Amphetamine Dependence
- Quetiapine for Mania In Preschool Children 4 to 6 Years of Age With Bipolar Disorder
ClinicalTrials.gov Identifier: NCT00181883 - Recruiting
Bipolar Disorder; Mania
- Quetiapine Fumarate (SEROQUEL) used as an Adjunct to Mood Stabilizers in the Treatment of Bipolar I Disorders
ClinicalTrials.gov Identifier: NCT00107731 - Completed
Bipolar Disorder
- Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency
ClinicalTrials.gov Identifier: NCT00498628 - Not yet recruiting
Alcoholism; Alcohol Abuse
- Methamphetamine-Quetiapine Interactions in Humans
ClinicalTrials.gov Identifier: NCT00567866 - Not yet recruiting
Methamphetamine Dependence
- An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence
ClinicalTrials.gov Identifier: NCT00223210 - Recruiting
Bipolar Disorder; Cocaine Dependence
- Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder
ClinicalTrials.gov Identifier: NCT00306540 - Recruiting
Post-Traumatic Stress Disorder
- Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD
ClinicalTrials.gov Identifier: NCT00579280 - Recruiting
Bipolar Disorder; Panic Disorder; Generalized Anxiety Disorder
- "A Double-Blind Randomized Placebo Controlled Study of Quetiapine for the Treatment of Depression in Adolescents With Bipolar Disorder"
ClinicalTrials.gov Identifier: NCT00232414 - Completed
Bipolar I Disorder; With Acute Depressive Episode
- Evaluating Quetiapine Fumarate (SEROQUEL) in the Treatment of Alcohol Dependency in Patients with Bipolar Disorder
ClinicalTrials.gov Identifier: NCT00114686 - Completed
Bipolar Disorder; Alcoholism
- Safety and Efficacy Trial of the Use of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Patients with Bipolar Depression
ClinicalTrials.gov Identifier: NCT00060489 - Completed
Bipolar Disorder; Depression, Bipolar
- Seroquel Acute Manic
ClinicalTrials.gov Identifier: NCT00139074 - Active, not recruiting
Bipolar I Disorder (DSM-IV 296.01, DSM-IV 296.4, DSM-IV 296.61)
- Quetiapine for Primary Insomnia Patients : A Randomized Controlled Trial
ClinicalTrials.gov Identifier: NCT00328822 - Not yet recruiting
Primary Insomnia
- Quetiapine for Bipolar Disorder and Alcohol Dependence
ClinicalTrials.gov Identifier: NCT00457197 - Recruiting
Bipolar Disorder; Alcohol Dependence
- Quetiapine vs Haloperidol Decanoate for the Long Term Treatment of Schizophrenia and Schizoaffective Disorder
ClinicalTrials.gov Identifier: NCT00018642 - Completed
Schizophrenia; Schizoaffective Disorder
- Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder.
ClinicalTrials.gov Identifier: NCT00521365 - Not yet recruiting
Bipolar Disorder; Affective Psychosis, Bipolar; Mania; Manic Disorder; Manic State
- Venlafaxine Augmentation
ClinicalTrials.gov Identifier: NCT00253266 - Not yet recruiting
Treatment Resistant Depression
- Effect of Quetiapine on Negative Symptoms and Cognition
ClinicalTrials.gov Identifier: NCT00305422 - Completed
Schizophrenia
- The Impact of Quetiapine on the Drug Abuse Patterns of Addicted Schizophrenic Patients
ClinicalTrials.gov Identifier: NCT00295412 - Completed
Schizophrenia; Substance Use Disorders
- Safety and Efficacy Maintenance Study of Quetiapine SR to Treat GAD Patients.
ClinicalTrials.gov Identifier: NCT00314210 - Completed
Anxiety Disorders
- Dose Finding of Quetiapine Fumarate 200mg vs 400mg in First Episode Psychosis
ClinicalTrials.gov Identifier: NCT00449397 - Completed
Psychosis
- Fast Titration Of Quetiapine Versus Currently Approved Titration
ClinicalTrials.gov Identifier: NCT00254813 - Completed
Psychotic Disorders
- Rapid Dose Escalation of Quetiapine Versus Conventional Escalation in Acute Schizophrenic Patients
ClinicalTrials.gov Identifier: NCT00254787 - Completed
Schizophrenia
- Quetiapine Fumarate Bipolar Maintenance Monotherapy
ClinicalTrials.gov Identifier: NCT00314184 - Completed
Bipolar Disorder
- Evaluation of Effectiveness and Safety of Paliperidone ER (Extended-Release) Compared With Quetiapine in Patients With Schizophrenia
ClinicalTrials.gov Identifier: NCT00334126 - Completed
Schizophrenia
- Schizophrenia Sensory Gating Deficit With Quetiapine
ClinicalTrials.gov Identifier: NCT00536783 - Completed
Schizophrenia
- Antipsychotic Response in Schizophrenia
ClinicalTrials.gov Identifier: NCT00018668 - Completed
Schizophrenia
- CATIE- Schizophrenia Trial
ClinicalTrials.gov Identifier: NCT00014001 - Completed
Schizophrenia
- Efficacy and Safety of Quetiapine Compared With Valproate in the Treatment of Patients With Bipolar Disorder and Rapid Cycling
ClinicalTrials.gov Identifier: NCT00254774 - Completed
Bipolar Disorder
- Efficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in the Treatment of Major Depressive Disorders
ClinicalTrials.gov Identifier: NCT00326144 - Completed
Major Depressive Disorder
- Efficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in Combination With an Antidepressant in the Treatment of Major Depressive Disorders
ClinicalTrials.gov Identifier: NCT00326105 - Completed
Major Depressive Disorder
- The Use of Quetiapine (Seroquel) in the Treatment of Social Phobia: Public Speaking Environment
ClinicalTrials.gov Identifier: NCT00407199 - Completed
Social Phobia
- Open label trial exploring a switch from oral medications, to risperidone depot microspheres
ClinicalTrials.gov Identifier: NCT00034775 - Completed
Schizophrenia
- Confirmatory Study of Seroquel® in the Treatment of Bipolar Depression
ClinicalTrials.gov Identifier: NCT00083954 - Completed
Bipolar Disorder
- A Study of Quetiapine for the Treatment of Mood Disorders in Adolescents
ClinicalTrials.gov Identifier: NCT00221468 - Completed
Mood Disorders
- Verkes Borderline Study: The Effect of Quetiapine on Borderline Personality Disordered Patients
ClinicalTrials.gov Identifier: NCT00254748 - Completed
Borderline Personality Disorder
- Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo and Active Control in Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00321490 - Completed
Major Depressive Disorder
- A comparison of Seroquel vs. Risperidone in Schizophrenia
ClinicalTrials.gov Identifier: NCT00034905 - Completed
Schizophrenia
- Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00320268 - Completed
Major Depressive Disorder
- Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Generalized Anxiety Disorder
ClinicalTrials.gov Identifier: NCT00329264 - Completed
Generalized Anxiety Disorder
- A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and of Quetiapine Fumarate (Seroquel®) as Potentiation SSRI’s, and SNRI’s Treatment in Major Depression With Anxiety
ClinicalTrials.gov Identifier: NCT00229645 - Completed
Major Depression With Comorbid Anxiety Symptoms
- Quetiapine Fumarate as Monotherapy in the Maintenance Treatment of Patients With Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00278941 - Completed
Major Depressive Disorder
- Open-Label Comparative Study of Risperidone Versus Olanzapine Versus Quetiapine for Mania in Children and Adolescents With Bipolar I and Bipolar II Disorder
ClinicalTrials.gov Identifier: NCT00182013 - Completed
Bipolar Spectrum Disorder
- Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)
ClinicalTrials.gov Identifier: NCT00043849 - Completed
Dementia; Parkinson Disease
- CATIE-Alzheimer's Disease Trial
ClinicalTrials.gov Identifier: NCT00015548 - Completed
Alzheimer's Disease
- Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo & Active Control in Generalized Anxiety Disorder
ClinicalTrials.gov Identifier: NCT00329446 - Completed
Generalized Anxiety Disorder
- Addition of Quetiapine in Obsessive Compulsive Disorder - Westenberg Study
ClinicalTrials.gov Identifier: NCT00318539 - Completed
Obsessive Compulsive Disorder
- Treatment of Depression With Quetiapine
ClinicalTrials.gov Identifier: NCT00174603 - Suspended
Major Depression With Psychotic Features
- Quetiapine for Cocaine Use and Cravings
ClinicalTrials.gov Identifier: NCT00232336 - Completed
Cocaine-Related Disorders; Substance-Related Disorders
- Quetiapine Augmentation in Severe Obsessive Compulsive Disorder
ClinicalTrials.gov Identifier: NCT00254735 - Completed
Obsessive Compulsive Disorder
- Quetiapine in Social Anxiety Disorder
ClinicalTrials.gov Identifier: NCT00215254 - Completed
Social Anxiety Disorder
- Seroquel plus Mood Stabilizer Compared to Placebo plus Mood Stabilizer in the Maintenance of Bipolar I Disorder
ClinicalTrials.gov Identifier: NCT00081380 - Completed
Bipolar Disorder
- Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia Patients
ClinicalTrials.gov Identifier: NCT00375557 - Terminated
Alzheimer's Disease; Dementia; Behavioral Symptoms
- Rapid Versus Conventional Titration of Quetiapine in Schizophrenia/Schizoaffective Disorder
ClinicalTrials.gov Identifier: NCT00457899 - Terminated
Schizophrenia; Schizoaffective Disorders; Psychotic Disorders
- Efficacy of Quetiapine in Generalised Social Anxiety Disorder
ClinicalTrials.gov Identifier: NCT00302770 - Terminated
Social Anxiety Disorder

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